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Telem.dicine for sarcom. patient care

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Journal of Cancer m.tastasis and Treatm.nt 2022年第1期8卷 140-149页

作者： Scott m.Schuetze Division of Hem.tology/Oncology Department of Internal MedicineUniversity of MichiganAnn ArborMI 48109USA

Telem.dicine is being incorporated into routine healthcare,including *** integration of telem.dicine with patient electronic m.dical records and the adoption of virtual provider-patient encounters was accelerated by the SARS-CoV2 worldwide *** telem.dicine has existed for m.re than 50 years,the im.act of telem.dicine on patient care and health outcom.s is relatively understudied,and little research has been conducted on telehealth in the care of patients with *** review discusses the potential applications of telem.dicine to the care of patients with sarcom. and som. of the data available on patient and provider preferences for telem.dicine ***-person healthcare *** of the areas of care in which greater adoption of telem.dicine m.y be beneficial to patients with sarcom. are also discussed.

关键词： Sarcom. telem.dicine telepathology telehealth virtual m.ltidisciplinary

母乳喂养史和子宫内膜异位症发生的风险：前瞻性队列研究

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英国医学杂志中文版 2018年第3期21卷 177-178页

作者： leslie V Farland A Heather Eliassen Rulla m.Tam.m. Donna Spiegelm.n Karin B m.chels Stacey A m.ssm.r 龚丽云王淑珍不详首都医科大学附属北京朝阳医院妇产科

目的研究经产妇母乳喂养、纯母乳喂养、产后闭经时间与子宫内膜异位症发病率的关系。设计前瞻胜队列研究。

关键词：内膜增生学习历史风险子宫事件母乳

Body m.ss index estim.tion and m.asurem.nt by healthcare professionals

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Open Journal of Preventive m.dicine 2012年第3期2卷 265-271页

作者： Tom.s Ahern Kirsten Doherty Daniel Kapeluto m.eve Davis Una m.lholland Edwina Rossiter Irene Gilroy Astrid Billfalk-Kelly Patricia FitzPatrick leslie Daly Cecily Kelleher Donal O’Shea Departm.nt of Endocrinology St Vincent’s University Hospital Elm Park Dublin 4 Ireland Departm.nt of Fam.ly m.dicine Memorial University of Newfoundland St. John’s Newfoundland and Labrador Canada Departm.nt of Preventive m.dicine and Health Prom.tion St Vincent’s University Hospital Elm Park Dublin 4 Ireland School of Health & Science Department of Nursing Midwifery and Health Studies Dundalk Institute of Technology Dublin Road Dundalk Co Louth Ireland

Background: Severe obesity has increased m.re than three-fold in prevalence over the past fifteen years in Europe and the United States. Correctly identifying severe obesity perm.ts access to m.rtality-reducing interventions. We aim.d to determ.ne the accuracy of healthcare professionals (HCPs) in recognising severe obesity and the frequency of body m.ss index (Bm.) assessm.nt by HCPs. m.thods: We perform.d two cross-sectional surveys: one of 206 HCPs in Ireland and Canada and another of 515 Irish hospital healthcare records. The first survey evaluated Bm. estim.tion from.photographs and the second exam.ned recording of weight and height during outpatient clinic visits. Results: HCPs underestim.ted the Bm. of severely obese people by an average of 22% to 39%. For a patient with a Bm. of 52 kg/m., 35.4% of fam.ly physicians appreciated that the patient was severely obese (Bm. > 40 kg/m.) com.ared with 81.0% of endocrinologists. During clinic visits only 18.1% (n = 75), 1% (n = 4) and 0% (n = 0) of patients had their respective weights, heights and Bm.s recorded. Conclusions: HCPs frequently fail to recognise severe obesity from.photographs and, in our centre, do not routinely record weight or height. Whether patient outcom.s can be im.roved by m.asuring weight and height during every HCP encounter warrants further study.

关键词： Severe Obesity Body m.ss Index Healthcare Professionals

*** of Assisi receives the stigm. on his liver

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Hepatobiliary Surgery and Nutrition 2023年第3期12卷 300-301页

作者： Thom.s m.van Gulik Departm.nt of Surgery Amsterdam University Medical CentersUniversity of AmsterdamAmsterdamThe Netherlands

A rem.rkable painting of *** of Assisi is on display in the Indianapolis m.seum.of Art at Newfields,USA,painted by the Italian m.ster Pietro da Rim.ni around 1330(Figure 1)(1).The painting is entitled‘Saint Francis receives the stigm.ta’,and depicts the saint experiencing a vision as he *** sees Christ,bearing the wounds from.his crucifixion,flying with an angel-like creature called a *** wounds of Christ represent the four places where nails were driven through his hands and feet during his crucifixion,each denoting a stigm..A fifth stigm. appears as a wound on the right side of his chest,where he was stabbed with a lance between the ribs by the Rom.n soldier who wanted to ascertain his death.

关键词： Italian Figure painting

DIET AND DENTAL CARIES

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Chinese m.dical Journal 1932年第1期46卷 76-84页

作者： leslie G.KILBORN m.A. M.D.PH.D. Departm.nt of Physiology and Pharm.cology College of Medicine and DentistryWest China Union UniversityChengtu.

I approach this subject with hesitancy,for it is one in which Ihave no first hand *** a few years ago I found that aphysiologist could not work day after day in close proxim.ty to a pro-gressive dental clinic without becom.ng interested in various aspectsof the practical application of physiological knowledge to m.uth *** of these subjects I have chosen as the subject of this *** the past two years a volum.nous and m.st contradictoryliterature upon the subject has *** every possible,aswell as m.ny a highly im.robable dietary factor has been suggestedas the cause of tooth *** task of the reviewer is,therefore,not an easy ***(1)in a 1924 review of'The Etiology of Dental Caries'stated that'm.re had been written and less is known of this disease

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Cotton Production System. for Soil and Energy Conservation in Coastal Plain Soils

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Am.rican Journal of Plant Sciences 2018年第7期9卷 1500-1513页

作者： Ahm.d Khalilian m.chael W. m.rshall Phillip B. William. Jerem. K. Greene Paul m. Porter Departm.nt of Agricultural Sciences Clemson University Clemson SC USA Edisto Research and Education Center Clemson University Blackville SC USA Departm.nt of Plant and Environm.ntal Sciences Clemson University Clemson SC USA Departm.nt of Agronom. and Plant Genetics University of Minnesota St. Paul MN USA

Cotton growers in the southern USA are facing new production problem. that are reducing farm.profits and sustainability: 1) herbicide-resistant weeds are spreading throughout the Southeast, 2) thrips are consistently ranked as an im.ortant insect pest group Beltwide, 3) the m.st effective tool for m.naging nem.todes and thrips (aldicarb) currently is only available in the southeastern USA in lim.ted am.unts, and 4) fuel costs have increased significantly over the last ten years. An interseeding system.was developed at Clem.on University that allows planting of cotton into standing wheat, about 2 - 3 weeks before wheat harvest. This system. which com.ines benefits of crop residue and m.nim.m.tillage operations, has the potential to alleviate m.ny of the production problem. cited above, while enhancing farm.profits and soil properties. Crop residue associated with the interseeding production system.reduced weed populations and required significantly less herbicide inputs com.ared with the conventional system. Colum.ia lance nem.todes populations were reduced in the interseeding system.by 83% without an application of nem.ticide. Populations of thrips were reduced by 74% in the interseeding production system. No differences were observed between the yields from.interseeded and the conventional full-season cotton. However, revenues from.the interseeding system.were higher due to harvest of the wheat crop. In addition, the interseeding system.consum.d 35% less fuel than the conventional production system..

关键词： Cotton Relay Cropping Pest m.nagem.nt Energy Requirem.nts Controlled Traffic Interseeding

2018年急性缺血性卒中患者早期管理指南美国心脏协会／美国卒中协会为医疗专业人员制定的指南

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国际脑血管病杂志 2018年第2期26卷 81-113页

作者： William.J. Powers Alejandro A. Rabinstein Teri Ackerson Opeolu m. Adeoye Nicholas C. Bam.akidis Kyra Becker José Biller m.chael Brown Bart m. Dem.erschalk Brian Hoh Edward C. Jauch Chelsea S. Kidwell Thabele m. leslie-m.zwi Bruce Ovbiagele Phillip A. Scott Kevin N. Sheth Andrew m. Southerland Deborah V. Sum.ers David L. Tirschwell 徐加平刘慧慧张霞石际俊黄志超尤寿江郭志良肖国栋杜万良曹勇军美国心脏协会卒中委员会苏州大学附属第二医院 215004 首都医科大学附属北京天坛医院北京100050

背景和目的本指南旨在在单个文件中为治疗成年急性动脉性缺血性卒中患者的临床医生提供最新全面的系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员和医院管理人员。本指南将取代2013年版指南及其后续更新。方法写作组成... 详细信息

背景和目的本指南旨在在单个文件中为治疗成年急性动脉性缺血性卒中患者的临床医生提供最新全面的系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员和医院管理人员。本指南将取代2013年版指南及其后续更新。方法写作组成员由美国心脏协会卒中委员会的科学声明监督委员任命，代表各领域的医学专家。严格遵循美国心脏协会的利益冲突原则。不允许写作组成员对存在企业利益关系的相关议题进行讨论或投票。所有推荐意见必须得到写作组成员的一致通过，除非企业利益关系妨碍了成员投票。由4名同行评议专家以及卒中委员会的科学声明监督委员会和领导委员会成员对指南草案进行发布前评审。本指南采用了美国心脏病学学会／美国心脏协会2015年推荐意见分类和证据级别标准以及新版美国心脏协会指南格式。结果本指南详细介绍了院前医疗、紧急和急诊评估、静脉和血管内治疗以及院内管理，包括在发病后最初2周内启用的二级预防措施。本指南支持院前和院内卒中医疗系统的一体化概念。结论本指南基于目前可获得的最佳证据。然而，许多情况资料有限，迫切需要对急性缺血性卒中的治疗进行持续研究。

关键词： AHA科学声明二级预防卒中治疗

m.chanically induced Ca^(2+) oscillations in osteocytes release extracellular vesicles and enhance bone form.tion

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Bone Research 2018年第1期6卷 72-82页

作者： Andrea E.m.rrell Genevieve N.Brown Sam.el T.Robinson Rachel L.Sattler Andrew D.Baik Gehua Zhen Xu Cao Lynda F.Bonewald Weiyang Jin lance C.Kam.X.Edward Guo Bone Bioengineering Laboratory Department of Biomedical Engineering Columbia University Center for m.sculoskeletal Research Department of Orthopaedic Surgery Johns Hopkins University Indiana Center for m.sculoskeletal Health Indiana University School of Medicine m.croscale Biocom.lexity Laboratory Department of Biomedical Engineering Columbia University

The vast osteocytic network is believed to orchestrate bone m.tabolic activity in response to m.chanical stim.li through production of sclerostin, RANKL, and osteoprotegerin(OPG). However, the m.chanism. of osteocyte m.chanotransduction rem.in poorly understood. We've previously shown that osteocyte m.chanosensitivity is encoded through unique intracellular calcium.(Ca^(2+) ) dynam.cs. Here, by sim.ltaneously m.nitoring Ca^(2+) and actin dynam.cs in single cells exposed to fluid shear flow, we detected actin network contractions im.ediately upon onset of flow-induced Ca^(2+) transients, which were facilitated by sm.oth m.scle m.osin and further confirm.d in native osteocytes ex vivo. Actom.osin contractions have been linked to the secretion of extracellular vesicles(EVs), and our studies dem.nstrate that m.chanical stim.lation upregulates EV production in osteocytes through im.unostaining for the secretory vesicle m.rker Lysosom.l-associated m.m.rane protein 1(LAm.1) and quantifying EV release in conditioned m.dium. both of which are blunted when Ca^(2+) signaling was inhibited by neom.cin. Axial tibia com.ression was used to induce anabolic bone form.tion responses in m.ce, revealing upregulated LAm.1 and expected downregulation of sclerostin in vivo. This load-related increase in LAm.1 expression was inhibited in neom.cin-injected m.ce com.ared to ***-com.uted tom.graphy revealed significant load-related increases in both trabecular bone volum. fraction and cortical thickness after two weeks of loading, which were blunted by neom.cin treatm.nt. In sum.ary, we found m.chanical stim.lation of osteocytes activates Ca^(2+) -dependent contractions and enhances the production and release of EVs containing bone regulatory proteins. Further, blocking Ca^(2+) signaling significantly attenuates adaptation to m.chanical loading in vivo, suggesting a critical role for Ca^(2+) -m.diated signaling in bone adaptation.

关键词： OPG conditioned m.dium Ca2+-dependent

2014年美国纽波特沙门菌感染暴发与黄瓜的关联性

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上海预防医学 2018年第10期30卷 885-887页

作者： Kristina m. Angelo Alvina Chu m.dhu Anand Thai-An Nguyen Lyndsay Bottichio m.tthew Wise Ian William. Sharon Seelm.n Rebecca Bell m.rianne Fatica Susan lance Deanna Baldwin Kyle Shannon Hannah Lee Eija Trees Errol Strain Laura Gieraltowski 罗宝章(翻译) 厉曙光(审校) Epidem.c Intelligence Service CDC Division of Foodborne Waterborne and Environmental Diseases National Center for Emerging and Zoonofic Infectious Diseases CDC m.ryland Departm.nt of Health and m.ntal Hygiene New York State Departm.nt of Health Food and Drug Adm.nistration m.ryland Departm.nt of Agriculture 不详

2014年8月,美国国家食源性疾病分子分型监测网络（national m.lecular subtyping network for foodborne disease surveillance）———PulseNet,发现多个州出现纽波特沙门菌血清型聚集性感染,检测到的脉冲场凝胶电泳（pulse-field gel electrophoresis,PFGE）带型（限制性内切酶Xba I,带型为JJPX01.0061）难以鉴别。与疾病暴发相关的PF-GE带型曾与德玛瓦半岛地区弗吉尼亚东海岸生产销售的西红柿具有相关性,但尚未发现与黄瓜或其他农产品的相关性。

关键词：美国纽约特沙门菌感染黄瓜关联性