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Telehealth utilization among Egyptian population and health institutional readiness:An exploratory study

中西医结合护理杂志(英文) 2023年第3期5卷 188-196页

作者： Basma Mohamed OSMAN Maaly Zayed MOHAMED Shaimaa Ali Mohamed ISMAIL lamiaa saad abd allah Marwa Mamdouh SHABAN Department of Community Health Nursing Faculty of NursingCairo UniversityCairoEgypt Department of Nursing Administration Faculty of NursingCairo UniversityCairoEgypt

Objective:This study aimed to assess the public’s perspectives and the health institutions’readiness for telehealth utilization in ***:A cross-sectional study design was employed,and data were collected from a convenient sample of 800 Egyptian citizens and 26 nursing administrators and information technology personnel from 16 governmental hospitals and 10 private hospitals between January and March *** Egyptian community utilization of telehealth questionnaire and the telemedicine hospital readiness assessment were used to collect the ***:The results revealed that 35.1%of the general Egyptian population used telehealth services and 43%expressed willingness to use them in *** perceived by the general Egyptian population,the most prevalent barriers to telehealth utilization were communication barriers(97.6%),lack of confidence in health professionals(77.6%),technological limitations(72.5%),the need for physical examination(25%),and privacy concerns(10%).Regarding hospital readiness,42%of governmental hospitals were not taking any initiative to implement telehealth services,and 15.4%were at the beginner level,meaning that some steps had been ***,the hospital was still far from being able to implement telehealth *** contrast,private hospitals were either at the beginner or advanced ***:Although the use of telehealth services in Egypt has increased,there is a need to address the barriers to public utilization and improve hospitals’readiness to implement telehealth services to enhance public usage.

关键词： Attitude barriers hospital readiness public use telehealth nursing practice nursing administration

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Artificial Fish Swarm for Multi Protein Sequences Alignment in Bioinformatics

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Computers, Materials & Continua 2022年第9期72卷 6091-6106页

作者： Medhat A.Tawfeek saad Alanazi A.A.abd El-Aziz Department of Computer Science College of Computer and Information SciencesJouf UniversitySaudi Arabia(KSA Department of Computer Science Faculty of Computers and InformationMenoufia UniversityEgypt Department of Information Systems College of Computer and Information SciencesJouf UniversitySaudi Arabia(KSA) Department of Information Systems and Technology Faculty of Graduates Studies and ResearchCairo UniversityEgypt

The alignment operation between many protein sequences or DNAsequences related to the scientific bioinformatics application is very *** is a trade-off in the objectives in the existing techniques of MultipleSequence Alignment (MSA). The techniques that concern with speed ignoreaccuracy, whereas techniques that concern with accuracy ignore speed. Theterm alignment means to get the similarity in different sequences with highaccuracy. The more growing number of sequences leads to a very complexand complicated problem. Because of the emergence;rapid development;anddependence on gene sequencing, sequence alignment has become importantin every biological relationship analysis process. Calculating the numberof similar amino acids is the primary method for proving that there is arelationship between two sequences. The time is a main issue in any alignmenttechnique. In this paper, a more effective MSA method for handling themassive multiple protein sequences alignment maintaining the highest accuracy with less time consumption is proposed. The proposed method dependson Artificial Fish Swarm (AFS) algorithm that can break down the mostchallenges of MSA problems. The AFS is exploited to obtain high accuracyin adequate time. ASF has been increasing popularly in various applicationssuch as artificial intelligence, computer vision, machine learning, and dataintensive application. It basically mimics the behavior of fish trying to getthe food in nature. The proposed mechanisms of AFS that is like preying,swarming, following, moving, and leaping help in increasing the accuracy andconcerning the speed by decreasing execution time. The sense organs that aidthe artificial fishes to collect information and vision from the environmenthelp in concerning the accuracy. These features of the proposed AFS make thealignment operation more efficient and are suitable especially for large-scaledata. The implementation and experimental results put the proposed AFS as afirst choice in th

关键词： Multiple sequence alignment swarm intelligence artificial fish swarm protein sequences

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Facile Synthesis of Naphtho[2,3-dJthiazoles, Naphtho[2,3-e]-[1,3,4]thiadiazines and Bis（naphtho[2,3-d]thiazolyl）copper（ll） Derivatives from Heteroylthiosemicarbazides

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Chinese Journal of Chemistry 2016年第8期34卷 814-822页

作者： Alaa A. Hassan Nasr K. Mohamed lamiaa E. abd EI-Haleem Stefan Brase Martin Nieger Chemistry Department Faculty of Science Minia University 61519 EI-Minia A. R. Egypt Institute of Organic Chemistry Karlsruhe Institute of Technology Fritz-Haber-Weg 6 76131 Karlsruhe Germany Laboratory of Inorganic Chemistry Department of Chemistry University of Helsinki P.O.Box55 (A. I. Virtasenaukio 1) 00014 Helsinki Finland

A one step synthesis protocol for the conversion of heteroylthiosemicarbazides and 2,3‐dichloro‐1,4‐naphthoquinone to naphtho[2,3‐ d ]thiazoles, naphtho[2,3‐ e ][1,3,4]thiadiazines as well as bis(naphtho[2,3‐ d ]thiazolyl)copper(II) derivatives is described. The products were conclusively confirmed by single crystal X‐ray analyses. A mechanism for the formation of the products is presented.

关键词： heteroylthiosemicarbazides 2,3‐dichloro‐1,4‐naphthoquinone naphtho[2,3‐d]thiazoles naphtho[2,3‐e]thiadiazines bis(naphtho[2,3‐d]thiazolyl)copper(II) derivatives

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The Gravitomagnetic and Field Magnetic Centrifugal Force Using Force and Four-Dimensional Potential Concepts

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Natural Science 2022年第3期14卷 125-132页

作者： Mohamed Yahia Shirgawi Zoalnoon Ahmed Abeid allah saad Mubarak Dirar abd-Alla Yagoub Department of Physics Faculty of Art and Science at Al Muznab Al Qassim University Buraydah Saudi Arabia Department of Physics Faculty of Arts and Sciences at Dhahran Aljanoub King Khalid University Abha Saudi Arabia Department of Physics Faculty of Science Sudan University of Science and Technology Khartoum Sudan

Unification of fundamental forces is the dream of physics. Nevertheless, unfortunately gravitational force operators to be isolated in its geometrical content from other forces. This encourages some researchers to propose the so-called gravimagnetic field to unify gravity with other forces and to explain some cosmological problems at the early universe. This motivates to construct a new model to confirm the existence of gravitomagnetic and a corresponding magnetic field associated with any field. Using the formal Newton definition of force and considering the magnetic force to be related to the time varying mass, the magnetic force is shown to be equal to the centrifugal force. This equality is typical when treating a particle as string. Using also the definition of force in terms of potential and electric force only, energy is shown to be conserved. The Newton force can be defined also in terms of four-dimensional potential with the time varying part related to the magnetic potential. When the particle is treated as a string, energy conservation holds, while for ordinary particle, the Lagrangian is conserved. The energy conservation holds for special relativity also for energy per unit mass. The definition of acceleration for forces that obeys inverse square law shows also the magnetic force is equal to the centrifugal force.

关键词： Gravitomagnetic Force Magnetic Force Newton Force Special Relativity Centrifugal Force Energy Lagrangian

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Wireless Sensor Networks Routing Attacks Prevention with Blockchain and Deep Neural Network

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Computers, Materials & Continua 2022年第3期70卷 6127-6140页

作者： Mohamed Ali Ibrahim A.abd El-Moghith Mohamed N.El-Derini saad M.Darwish Higher Institute for Tourism Hotels and ComputerAl-SeyoufAlexandria21533Egypt Department of Information Technology Institute of Graduate Studies and ResearchAlexandria University21526Egypt Department of Computer and Systems Engineering Faculty of EngineeringAlexandria UniversityAlexandria21544Egypt

Routing is a key function inWireless Sensor Networks(WSNs)since it facilitates data transfer to base *** attacks have the potential to destroy and degrade the functionality ofWSNs.A trustworthy routing system is essential for routing security andWSN *** methods have been implemented to build trust between routing nodes,including the use of cryptographic methods and centralized ***,the majority of routing techniques are unworkable in reality due to the difficulty of properly identifying untrusted routing node *** the moment,there is no effective way to avoid malicious node *** a consequence of these concerns,this paper proposes a trusted routing technique that combines blockchain infrastructure,deep neural networks,and Markov Decision Processes(MDPs)to improve the security and efficiency of WSN *** authenticate the transmission process,the suggested methodology makes use of a Proof of Authority(PoA)mechanism inside the blockchain *** validation group required for proofing is chosen using a deep learning approach that prioritizes each node’s *** are then utilized to determine the suitable next-hop as a forwarding node capable of securely transmitting *** to testing data,our routing system outperforms current routing algorithms in a 50%malicious node routing scenario.

关键词： Wireless sensor networks trusted routing deep neural network blockchain markov decision

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Mesenchymal stem cells are more effective than captopril in reverting cisplatin-induced nephropathy

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BIOCELL 2019年第2期43卷 73-79页

作者： ENTSAR A.saad REDA S.EL-DEMERDASH EMAN M.abd EI-FATTAH Chemistry Department Faculty of ScienceDamietta UniversityDamiettaEgypt Urology&Nephrology Center Faculty of MedicineMansoura UniversityEgypt

Cisplatin is a powerful anticancer drug but its nephrotoxic effects limit its clinical *** aimed to evaluate the effect of mesenchymal stem cells(MSCs)injection or of captopril to counteract the cisplatin-induction of *** isolation,preparation and tracking,transforming growth factor-β(TGF-β)and interleukin-10(IL-10)expressions,kidney function tests,oxidative stress state,and histological examinations were ***-induced nephropathy was indicated biochemically and confirmed *** treatment showed normal kidney architecture and significantly decreased oxidative stress and TGF-β while increased IL-10 and improved kidney function *** treated with cisplatin+captopril showed noticeable kidney histopathological *** positive impact of MSCs in amelioration of cisplatin-induced nephropathy via their ability to motivate functional and structural renal repair is evidenced.

关键词： Histopathology IL-10 Minerals Nephropathy Oxidative stress PCR Repair TGF-β

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Effects of cucumber mosaic virus-infected chilli plants on non-vector Bemisia tabaci (Hemiptera Aleyrodidae)

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Insect Science 2019年第1期26卷 76-85页

作者： Khalid A.saad M.N.Mohamad Roff Rebecca H.Hallett Idris B.abd-Ghani Faculty of Science and Technology School of Environmental and Natural Resource SciencesNational University MalaysiaBangi SelangorMalaysia Horticulture Research Centre HeadquartersMARDI-UPMSerdang SelangorMalaysia School of Environmental Sciences University of GuelphGuelphOntarioCanada

Plant virus infections are known to alter host plant attractiveness and suitability for insect *** study was conducted to determine how cucumber mosaic virus (CMV)-infected chilli plants affect the fitness and settling preferences ofnonvector whitefly,Bemisia tabaci adults under dual-choice conditions with volatile organic compounds analyzed using solid phase microextraction coupled with gas chromatography-mass spectrometry (GC-MS).Results showed that the presence of CIVIV in chilli plants substantially affects the settling preferences of the ***,which preferred to settle on noninfected *** of the egg stage and the longevity and fecundity of adult *** on CMV-infected chilli plants were not markedly different from those on noninfected chilli *** contrast,the developmental time from egg to adult was significantly reduced in CMV-infected chilli plants compared to the noninfected *** results also showed that CMV-infected chilli plants released significantly more linalool and phenylacetaldehyde than noninfected ***,it was suggested that the behavioral response of *** might be modified by CMV-infected plants,which alter the release of specific headspace *** on these results,the modification of plant volatile profiles may help in enhancing the effectiveness of biological control and the protection of crop plants against ***.

关键词： Bromoviridae Capsicum anmium cucumovirus in sect-pathogen interactions whitefly

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Mechanism of antagonistic effects of Andrographis paniculata methanolic extract against Staphylococcus aureus

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Asian Pacific Journal of Tropical Medicine 2017年第7期10卷 747-757页

作者： Roslinah Mohamad Hussain Zayan Nabilah Rasyidah abd.Razak Wan Mazlina Md saad Maimunah Mustakim Department of Medical Laboratory Technology Faculty of Health SciencesUniversiti Teknologi MARA(UiTM)SelangorMalaysia

Objective: To investigate the effects of Andrographis paniculata(Burm.f.) Wall. Ex Nees(A. paniculata) on expressions and activities of catalase, superoxide dismutase and alkylhydroperoxide reductase C in Staphylococcus aureus(S. aureus) with respect to its survival in vitro. Methods: Antioxidative property of methanolic leaves extract of A. paniculata(0.06 mg/m L). Minimum inhibitory concentration(MIC) was determined by its ability to reduce hydrogen peroxide(H_2O_2) toxicity against S. aureus ATCC 25923(3.8×10~8 cfu/m L). Effects of the extract on expressions of kat A(encoding catalase), sod A and sod M [encoding superoxide dismutases(SODs)], and ahp C [encoding alkylhydroperoxide reductase C(AhpC)] in S. aureuswere determined by RT-q PCR and corresponding enzyme activity assays were performed. Nitroblue tetrazolium reduction(NBT) assay was performed to determine effects of the extract on intracellular and extracellular levels of O_2-in S. aureus. Results: Cells challenged with 7.5 mmol/L H_2O_2 showed 0% survival in 30 min whereas 25% survived after treatment with the extract and H_2O_2. Cells that were treated with the extract alone had 43% survival in the same exposure period. Expressions of sod A and sod M genes in extract-treated cells were lowered 0.8-fold and 0.7-fold, respectively with decrease in total SOD activity of 26.8 U compared to untreated cells, 32.4 U(P<0.05). In contrast, extract-treated S. aureus cells showed 3.3-fold increase in kat A expression with corresponding increase in catalase activity of 1.828 U compared to untreated cells which was 1.248 U,(P<0.05). More profoundly, ahp C expression was increased 61-fold in extract-treated cells,(P<0.05) with corresponding increase in Ahp C activity of 0.018 U compared to untreated cells, 0.012U,(P<0.05). Extract-treated cells had significantly lower intra-and extracellular O_2-levels with absorbance readings(A_(575nm)) of 0.340 and 0.524 compared to untreated cells which were 0.516 and 0.928(P<0.05)

关键词： Antagonistic effects Andrographis paniculata Oxidative stress resistance Staphylococcus aureus Superoxide dismutase Catalase

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Biosynthesis of raw starch degradingβ-cyclodextrin glycosyltransferase by immobilized cells of Bacillus licheniformis using potato wastewater

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BIOCELL 2021年第6期45卷 1661-1672页

作者： YASSER S.MOSTAFA saad A.ALAMRI SULIMAN A.ALRUMMAN TAREK H.TAHA MOHAMED HASHEM MAHMOUD MOUSTAFA lamiaa I.FAHMY Department of Biology College of ScienceKing Khalid UniversityAbha9004Saudi Arabia Prince Sultan Bin abdulaziz Center for Environmental and Tourism Research and Studies King Khalid UniversityAbha9004Saudi Arabia Environmental Biotechnology Department Genetic Engineering and Biotechnology Research InstituteCity of Scientific Research&Technological ApplicationsNew Borg El-Arab City21934Egypt Department of Botany and Microbiology Faculty of ScienceAssiut UniversityAssiut71515Egypt Department of Botany and Microbiology Faculty of ScienceSouth Valley UniversityQena83523Egypt Department of Microbiology and Immunology Faculty of PharmacyOctober University for Modern Science and ArtGiza12451Egypta

The study was sought to enhance the synthesis of thermal stableβ-cyclodextrin glycosyltransferase(β-CGTase)using potato wastewater as a low-cost medium and assess the degree to which it is efficient for industrial production ofβ-cyclodextrin(β-CD)from raw potato *** bacteria producingβ-CGTase was isolated from Saudi Arabia and the promising strain was identified as Bacillus licheniformis using phylogenetic analysis of the 16S rRNA ***-encapsulated cultures exhibited twice-fold ofβ-CGTase production more than free *** electron microscopy(SEM)of polymeric capsules indicated the potential for a longer shelf-life,which promotes the restoration of activity in bacterial cells across semi-continuous fermentation ofβ-CGTase production for 252 *** optimal conditions forβ-CGTase synthesis using potato wastewater medium were at 36 h,pH of 8.0,and 50°C with 0.4%potato starch and 0.6%yeast extract as carbon and nitrogen sources,*** purified enzyme showed a specific activity of 63.90 U/mg with a molecular weight of∼84.6 kDa as determined by SDS-PAGE *** high enzyme activity was observed up to 60°C,and complete stability was achieved at 75°*** levels of activity and stability were shown at pH 8.0,and the pH range from 7.0–10.0,*** enzyme has an appreciable affinity for raw potato starch with a Km of 5.7×10−6 M and a Vmax of 87.71μmoL/mL/min.β-CD production was effective against 25 U/g of raw potato *** outcomes demonstrated its feasibility to develop a fermentation process by integrating the cost-effective production ofβ-CGTase having distinctive properties forβ-CD production with ecofriendly utilization of potato wastewater.

关键词： Potato wastewater Bacillus licheniformis β-CGTase 16S rDNA gene Semi-continuous fermentation β-cyclodextrin

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A smart simple spectrophotometric method for simultaneous determination of binary mixtures

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Journal of Pharmaceutical Analysis 2012年第5期2卷 382-385页

作者： Eman S.Elzanfaly Ahmed S.saad abd Elaziz B.abd Elaleem Analytical Chemistry Department Faculty of PharmacyCairo UniversityKasr-El Aini Street11562 CairoEgypt

A new simple spectrophotometric method was developed for the simultaneous determination of drugs with interfering spectra in binary mixtures without previous separation. The new method is based on a simple modification for the ratio subtraction method. This modification enabled wider range of application. The proposed ratio difference method was applied for the determination of brimonidine and timolol in laboratory prepared mixtures with mean percentage recoveries 100.40±2.29 and 101.23± 1.30 respectively, and in their pharmaceutical formulation with mean percentage recoveries 101.08±0.44 and 100.66±0.52 respectively. The suggested ratio difference method was validated according to USP guidelines and can be applied for routine aualitv control testing.

关键词： Spectrophotometry Ratio difference Binary mixtures Brimonidine Timolol

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