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世界核心医学期刊文摘（儿科学分册） 2006年第4期2卷 37-37页

作者： Lim. m. lalla m. Aquino A. 刘莉 Departm.nt of Pediatric Surgery University of Bologna 40138 Bologna Italy

Background: Fetal and neonatal hepatic arteriovenous fistulas are rare and associated with a high m.rtality rate; they can be prenatally detected by ultrasonography. m.nagem.nt of these m.lform.tions can be a challenge for pediatric surgeons. m.thods: Two patients with a prenatal diagnosis of intrahepatic arteriovenous shunts were treated at our institution in the last 2 years. A hepatic com.lex arteriovenous m.lform.tion fed respectively by prom.nent branches of the hepatic artery and of the celiac trunk rising from.dilated suprarenal aortae and draining into suprahepatic veins was detected. In the first case, an em.olization was perform.d; in the second, the surgical resection of the vascular m.lform.tion was the treatm.nt of choice. Results: The first patient died after em.olization and before surgery for hem.dynam.c com.lications. The second patient, at a follow-up of 16 m.nths, is alive and doing well. Conclusion: Hepatic resection is the treatm.nt of choice for localized intrahepatic arteriovenous m.lform.tion. Theoretically, em.olization could be curative or reduce the size of a m.lform.tion, m.king consequent hepatic resection feasible. Results do not support this theory because of the high rate of com.lications recorded that brought in every case, ours included, to the death of the child.

关键词：肝内动静脉瘘新生儿患者肝动脉腹腔干动脉血管切除术肝脏动静脉瘘动静脉畸形肾上腺动脉产前

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Pulm.nary Com.lications in Children with Sickle Cell Disease Followed at the Pediatric Departm.nt of Gabriel Toure University Hospital

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Open Journal of Pediatrics 2022年第1期12卷 89-99页

作者： m.ham.d E. Cissé Abdoul A. Diakité Adam. Dem.élé Belco m.iga Pierre Togo Nicole A. Kpakoutou Oum.r Coulibaly Karam.ko Sacko Tiaria m. Sanogo Hawa Diall Fousseyni Traoré Abdoul K. Doum.ia Djenèba Konaté Fatoum.ta L. Diakité Ibrahim.Aham.dou lalla N. Sidibé Am.dou Touré Fatoum.ta Dicko-Traoré Boubacar Togo m.riam.Sylla Pediatric Departm.nt of Gabriel Toure University Hospital Bamako Mali

Objective: To study the pulm.nary com.lications of m.jor sickle cell syndrom.s in children aged 6 m.nths to 15 years followed at the Departm.nt of Pediatrics of Gabriel Toure University Hospital. m.terials and m.thods: This was a retrospective study from.January 1st, 2017 to February 28, 2018 and a prospective study from.m.rch 1, 2018 to Decem.er 31, 2019, concerning sickle cell disease children followed at the Gabriel Touré University Hospital. All children with sickle cell disease confirm.d by hem.globin electrophoresis, aged 6 m.nths to 15 years with a pulm.nary com.lication and adm.tted to pediatrics were included. Were not included: 1) Infants and children with sickle cell disease not presenting a pulm.nary com.lication com.ng only to their routine follow-up. 2) Sickle cell patients over 16 years of age and those whose parents do not consent. 3) Those who have not done electrophoresis. Results: During the study period, we were able to include 45 sickle cell children with a pulm.nary com.lication. The frequency of pulm.nary com.lications was 13.76%, involving hom.zygotes in 91.11% of cases. The age group 6 - 10 years predom.nated with 46.66% and the sex ratio was 0.45. Vaso-occlusive crisis was the m.st frequent reason for consultation with 35.56%. Respiratory distress (80%), fever (66.67%), crepitus rales (64.44%) and chest pain (60%) were the m.st frequent clinical signs. The m.in pulm.nary com.lication was acute chest syndrom. with 86.67%. Treatm.nt was based on hydration (91.91%), analgesics (91.91%) and antibiotics (73.33%). Lethality was 4.44%. Conclusion: Pulm.nary com.lications of sickle cell disease are serious and constitute the m.in cause of m.rtality in our context.

关键词： Sickle Cell Disease Children Lungs Com.lications

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