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Characterization of the generalized permeability jail in tight reservoirs by analyzing relative-permeability curves and numerical simulation

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Petroleum Science 2023年第5期20卷 2939-2950页

作者： Feng-Peng lai Zhi-Ping Li He-Xin wei wei Zhang School of Energy Resources China University of GeosciencesBeijing100083China Beijing Key Laboratory of Unconventional Natural Gas Geological Evaluation and Development Engineering Beijing100083China Changchun Oil Production Plant of Jilin Oilfield PetroChinaChangchun130062JilinChina Changqing Oilfield Company PetroChinaXi'an710018ShaanxiChina

This study comprehensively characterizes the boundary values of generalized permeability jail in tight reservoirs through relative-permeability curve analysis,numerical simulation,and economic evaluation.A total number of 108 relative-permeability curves of rock samples from tight reservoirs were obtained,and the characteristics of relative-permeability curves were *** irreducible water saturation(Swi)mainly ranges from 20% to 70%,and the residual gas saturation(Sgr)ranges from 5% to 15% for 55% of the *** relative-permeability curves are categorized into six types(Category-Ⅰ to Ⅵ)by analyzing the following characteristics:The relative permeability of gas at Swi,the relative permeability of water at Sgr,and the relative permeability corresponding to the isotonic *** relative permeability curves were normalized to facilitate numerical simulation and evaluate the impact of different types of curves on production *** results of simulation show significant difference in production performance for different types of relative-permeability curves:Category-Ⅰ corresponds to the case with best well performance,whereas Categories-Ⅴ and Ⅵ correspond to the cases with least production *** results of economic evaluation show a generalized permeability jail for Categories-Ⅳ,Ⅴ,and Ⅵ,and the permeability jail develops when the relative permeability of gas and water is below *** study further quantifies the range of micro-pore parameters corresponding to the generalized permeability jail for a tight sandstone reservoir.

关键词： Generalized permeability jail Characterization Relative permeability curve Numerical simulation Pore structure

Analytic Solutions for the Spectral Responses of RCA-Grating-Based Waveguide Devices

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Chinese Physics Letters 2012年第12期29卷 102-104页

作者： ZENG Xiang-Kai wei lai School of Optoelectronic Information Chongqing University of TechnologyChongqing 4000542Department of Electronic and Information EngineeringHong Kong Polytechnic UniversityHong Kong

Analytic solutions(ASs)for the spectral responses of waveguide devices with raised-cosine-apodized(RCA)gratings are *** waveguide devices include short-and long-period RCA-gratings,RCA-grating-based interferometers as Fabry-Perot,Mach-Zehnder and Michelson *** calculations based on the analytic solutions are demonstrated and compared with those based on the transfer matrix(TM)method preferred,which has confirmed that the AS-based analysis is with enough accuracy and several thousands times the efficiency of the TM method.

关键词： interferometer waveguide Waveguide

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魏福良教授治疗失眠症经验举隅

中国中医药现代远程教育 2025年第2期23卷 71-74页

作者：陈赟魏福良安徽中医药大学第二附属医院脑病五科安徽合肥230061

文章对魏福良教授治疗失眠症的经验进行了总结。失眠症为中医临床常见病,安徽省名老中医魏福良主任医师认为其诊治需从“五脏藏神”理论着手,诊脉查舌,辨证论治。魏师精研针、灸、药结合之道,用针本神,以脏腑辨证为本,精研刺灸之法,脏... 详细信息

文章对魏福良教授治疗失眠症的经验进行了总结。失眠症为中医临床常见病,安徽省名老中医魏福良主任医师认为其诊治需从“五脏藏神”理论着手,诊脉查舌,辨证论治。魏师精研针、灸、药结合之道,用针本神,以脏腑辨证为本,精研刺灸之法,脏腑经络并治,令阴平阳秘;针药同施,内外并治,脏腑气血阴阳调和而神自安。

关键词：不寐失眠针灸疗法魏福良名医经验

Design of a Two-Step Calibration Method of Kinematic Parameters for Serial Robots

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Chinese Journal of Mechanical Engineering 2017年第2期30卷 438-448页

作者： wei WANG Lei WANG Chao yun School of Mechanical Engineering and Automation Beihang University State Key Lab of Digital Manufacturing Equipment and Technology Huazhong University of Science and Technology

Serial robots are used to handle workpieces with large dimensions, and calibrating kinematic parameters is one of the most efficient ways to upgrade their accuracy. Many models are set up to investigate how many kinematic parameters can be identified to meet the minimal principle, but the base frame and the kinematic parameter are indistinctly calibrated in a one-step way. A two-step method of calibrating kinematic parameters is proposed to improve the accuracy of the robot＇s base frame and kinematic parameters. The forward kinematics described with respect to the measuring coordinate frame are established based on the product- of-exponential （POE） formula. In the first step the robot＇s base coordinate frame is calibrated by the unit quaternion form. The errors of both the robot＇s reference configuration and the base coordinate frame＇s pose are equivalently transformed to the zero-position errors of the robot＇s joints. The simplified model of the robot＇s positioning error is established in second-power explicit expressions. Then the identification model is finished by the least square method, requiring measuring position coordinates only. The complete subtasks of calibrating the robot＇ s 39 kinematic parameters are finished in the second step. It＇s proved by a group of calibration experiments that by the proposed two-step calibration method the average absolute accuracy of industrial robots is updated to 0.23 mm. This paper presents that the robot＇s base frame should be calibrated before its kinematic parameters in order to upgrade its absolute positioning accuracy.

关键词： Kinematic parameter Calibration Error model Product of exponential Industrial robot

Radiation damage of 1Cr18Ni9Ti and Zr-Ti-Al alloys due to energetic particle irradiation

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Acta Metallurgica Sinica(English Letters) 2012年第1期25卷 29-39页

作者： Maosheng CHAI Wensheng lai Zhengcao LI wei FENG Department of Materials Science and Engineering Tsinghua UniversityBeijing 100084China

The radiation damage of 1Cr18Ni9Ti stainless steel and the Zr-Ti-Al alloy by 200 keV Xe＋ ions bombardment at the fluence ranging from 1×1014 to 8×1015 ions/cm2 has been investigated by conventional transmission electron microscope, X-ray diffraction line profile analysis （XRDLPA） and nanoindentation. XRDLPA shows that the order of magnitude of dislocation density in both materials remains almost unchanged up to the highest irradiation dose. Selected-area electron diffraction combined with bright and dark field image indicates that 1Cr18Ni9Ti is more easily damaged than the Zr-Ti-Al alloy. With increasing the ions fluence, the radiation damage became more severe in 1Cr18Ni9Ti, accompanied with phase transition and partial amorphization. The nano-hardness was found to increase rapidly with increasing ion fluence till the dose of 1×1015 ions/cm2, and then gradually saturate with dose. The enhancement of hardness in irradiated materials is due to irradiation-induced defects acting as barriers to dislocation motion.

关键词： Damage structure Zr-Ti-Al alloy 1Cr18Ni9Ti stainless steel XRD TEM Irradiation Depth profile

Net zero emission goals demand worldwide cooperation

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National Science Review 2023年第11期10卷 93-95页

作者： Shi Xue Dou wei-Hong lai Chris Cook Institute of Energy Materials Science University of Shanghai for Science and Technology Institute for Superconducting and Electronic Materials University of Wollongong Faculty of Engineering and Information Sciences University of Wollongong

The serious threat of climate change has become a reality of daily life all over the world. There is no priority facing humans at present more urgent than climate change. The goal of achieving net zero emissions (NZEs) within a time frame short enough to avoid catastrophic changes can only be accomplished through worldwide cooperation.

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High Temperature Seedless Synthesis of Au NRs Using BDAC/CTAB Co-surfactant

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Chinese Journal of Chemical Physics 2008年第5期21卷 476-480页

作者： Min Li lai wei Xian Zhang Xue-feng Yu Department of Physics Key Laboratory of Acoustic and Photonic Materials and Devices of Ministry of Education Wuhan University Wuhan 430072 China

Au nanorods have been successfully synthesized at 90 ℃ by using hexadecyltrimethylammonium bromide （CTAB） and benzyldimethylammoniumchloride hydrate （BDAC） co-surfactant. At 90 ℃, the reaction time was less than 10 s, and the longitudinal surface plasmon absorption band could vary between 680 and 770 nm by adjusting the molar ratio of BDAC to CTAB from 2 to 0.5. At 90 ℃, nanorods with a longitudinal surface plasmon absorption peak of 770 nm can be obtained when the molar ratio of BDAC to CTAB was 3：2.

关键词： Au nanorod Hexdecyltrimethylammonium bromide Benzyldimethylammoniumchloride hydrate High temperature

Frequency of IL-10-producing regulatory B cells associated with disease activity in thyroid-associated orbitopathy

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International Journal of Ophthalmology(English edition) 2018年第9期11卷 1458-1462页

作者： yun-Gang Ding Guo Chen Qian Li Xiao-Feng Wen lai wei Hua-Sheng Yang State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060Guangdong ProvinceChina Qindao Ludong Eye Hospital Qingdao 266600Shandong ProvinceChina Ningxia Eye Hospital People's Hospital of Ningxia Hui Autonomous Regionthe First Clinical College of Northwest University for Nationalitiesthe Cooperative Teaching Hospital of North Minzu UniversityYinchuan 750001Ningxia Hui Autonomous RegionChina

AIM： To investigate the association between IL-10-producing regulatory B（B10） cells and the clinical features of thyroid-associated orbitopathy（TAO）. METHODS： A total of 30 patients with TAO were recruited at Zhongshan Ophthalmic Center from May 2015 to December 2015. Peripheral blood mononuclear cells（PBMCs） were separated from blood samples of 30 TAO patients and 16 healthy controls and stimulated with CD40 ligand and CpG for 48h. The frequency of IL-10＋ B cells was examined by flow cytometry and the correlation between the frequency of IL-10＋ B cells and clinical features of TAO was analyzed by SPSS. RESULTS： The frequency of IL-10＋ B cells among CD19＋ B cells in TAO patients was significantly lower than in healthy controls（TAO： 4.66%±1.88% vs healthy control： 6.82%±2.40%, P〈0.01）. The frequency of IL-10＋ B cells showed a positive correlation with disease activity of TAO measured by Clinical Activity Score（CAS）（r=0.50, P〈0.01）, and became higher in TAO patients with family history of Graves＇ disease（GD）（P=0.04）. CONCLUSION： The decrease of the frequency of IL-10＋ B cells in TAO patients indicates the deficiency of B10 cells in TAO, and the positive association with disease activity suggests its important role in TAO inflammation regulation.

关键词： thyroid-associated orbitopathy regulatory B cells interleukin-10 flow cytometry

Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

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Science China Chemistry 2025年第01期 369-376页

作者： Song-Meng Wang Hao Nian Yan-Fang Wang Li-Shuo Zheng Yu-Tao Zheng Yi-wei Dong Liping Huang Xiaoping Wang wei Jiang Liu-Pan Yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of N-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

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