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Journal of Iron and Steel Research International 2024年第3期31卷 622-633页

作者： Pu Wang liang Chen Qun-wei Tang Wei-tao li Shao-xiang li Jia-quan Zhang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Weifang Special Steel Group Co..Ltd. Weifang 262400ShandongChina School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China

The propagation form of internal cracks induced by continuous casting soft reduction and the control strategy for enhancing the internal quality of 45 steel through industrial trials and a three-dimensional flow-heat transfer-solidification coupling model were *** results showed that the internal cracks induced by soft reduction exhibited a characteristic of being"coarse in the middle and fine at both ends",and displayed an elliptical arc distribution on the loose side of the strand cross *** cracks originated within the brittle temperature range and propagated inward to the liquid impenetrable temperature and outward to the zero ductility temperature or *** control strategy for enhancing the internal quality of the 45 steel strand through soft reduction is to adjust the casting speed or the reduction zone appropriately,ensuring that the central solid fraction of the reduction zone falls within the range of *** this point,a reasonable reduction amount is allocated to eliminate the center shrinkage cavities and center segregation,even if it results in minor reduction-induced cracks.

关键词： Continuous casting Soft reduction Crack propagation Internal quality Control strategy

A Modeling Study Recurrent Tuberculosis Towards End TB Strategy—China,2025-2035

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China CDC weekly 2024年第35期6卷 885-890页

作者： tao li Xin Du Zhongwei Jia Yanlin Zhao Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Chinese Center for Disease Control and Prevention BeijingChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina Center for Intelligent Public Health Institute for Artificial IntelligencePeking UniversityBeijingChina Department of Global Health School of Public HealthPeking UniversityBeijingChina Center for Drug Abuse Control and Prevention National Institute of Health Data SciencePeking UniversityBeijingChina

Summary What is already known about this topic?The recurrence of tuberculosis(TB)following successful treatment presents a significant *** is added by this report?Achieving the global End TB Strategy milestones and targets with the current strategies in China is ***,interventions following recovery to prevent recurrence,in conjunction with preventive treatment for latent TB infection(LTBI),will aid in meeting these objectives.

关键词： Strategy tuberculosis treatment

Boosting High-Voltage Practical lithium Metal Batteries with Tailored Additives

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Nano-Micro Letters 2024年第12期16卷 23-41页

作者： Jinhai You Qiong Wang Runhong Wei li Deng Yiyang Hu li Niu Jingkai Wang Xiaomei Zheng Junwei li Yao Zhou Jun-tao li College of Energy Xiamen UniversityXiamen 361005People’s Republic of China Magnetism Key Laboratory of Zhejiang Province College of Materials and ChemistryChina Jiliang UniversityHangzhou 310018People’s Republic of China Laboratory for Soft Matter and Biophysics Department of Physics and AstronomyKU Leuven3001 LeuvenBelgium State Key Lab of Physical Chemistry of Solid Surface College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005People’s Republic of China Department of Chemical Engineering KU LeuvenCelestijnenlaan 200F3001 LeuvenBelgium College of Chemistry and Chemical Engineering Northwest Normal UniversityLanzhou 730070GansuPeople’s Republic of China

The lithium(li)metal anode is widely regarded as an ideal anode material for high-energy-density ***,uncontrolled li dendrite growth often leads to unfavorable interfaces and low Coulombic efficiency(CE),limiting its broader ***,an ether-based electrolyte(termed FGN-182)is formulated,exhibiting ultra-stable li metal anodes through the incorporation of liFSI and liNO3 as dual *** synergistic effect of the dual salts facilitates the formation of a highly robust SEI film with fast li+transport ***,li||Cu half cells exhibit an average CE reaching up to 99.56%.In particular,pouch cells equipped with high-loading lithium cobalt oxide(LCO,3 mAh cm^(-2))cathodes,ultrathin li chips(25μm),and lean electrolytes(5 g Ah-1)demonstrate outstanding cycling performance,retaining 80%capacity after 125 *** address the gas issue in the cathode under high voltage,cathode additives 1,3,6-tricyanohexane is incorporated with FGN-182;the resulting high-voltage LCO||li(4.4 V)pouch cells can cycle steadily over 93 *** study demonstrates that,even with the use of ether-based electrolytes,it is possible to simultaneously achieve significant improvements in both high li utilization and electrolyte tolerance to high voltage by exploring appropriate functional additives for both the cathode and anode.

关键词： li metal anode li dendrites liNO_(3) 1,3,6-tricyanohexane Pouch cells

Image format pipeline and instrument diagram recognition method based on deep learning

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Biomimetic Intelligence & Robotics 2024年第1期4卷 36-44页

作者： Guanqun Su Shuai Zhao tao li Shengyong liu Yaqi li Guanglong Zhao Zhongtao li Shandong Qingniao IIoT Co. ltd.Jinan 250014China Jinan Housing and Urban-Rural Development Bureau Jinan 250012China State Grid Shandong Electric Extrahigh Voltage Company Jinan 250018China School of Information Science and Engineering University of JinanJinan 250022China

In this study,we proposed a recognition method based on deep artificial neural networks to identify various elements in pipelines and instrumentation diagrams(P&ID)in image formats,such as symbols,texts,and ***,the P&ID image format is recognized manually,and there is a problem with a high recognition error rate;therefore,automation of the above process is an important issue in the processing plant *** China National Offshore Petrochemical Engineering *** the image set used in this study,which contains 51 P&ID drawings in the *** converted the PDF P&ID drawings to PNG P&IDs with an image size of 8410×*** addition,we used labeling software to annotate the images,divided the dataset into training and test sets in a 3:1 ratio,and deployed a deep neural network for *** method proposed in this study is divided into three *** first step segments the images and recognizes symbols using YOLOv5+*** second step determines text regions using character region awareness for text detection,and performs character recognition within the text region using the optical character recognition *** third step is pipeline recognition using YOLOv5+*** symbol recognition accuracy was 94.52%,and the recall rate was 93.27%.The recognition accuracy in the text positioning stage was 97.26%and the recall rate was 90.27%.The recognition accuracy in the character recognition stage was 90.03%and the recall rate was 91.87%.The pipeline identification accuracy was 92.9%,and the recall rate was 90.36%.

关键词： Deep learning Image processing Piping and instrumentation Object recognition Pipeline recognition

Numerically investigation of particle distribution in industrial-scale DTB crystallizer based on CFD

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Particuology 2024年第10期93卷 186-202页

作者： Jinju Ma Weiyu Wang Wei Huang Wei liu Xinding Yao tao li Baozeng Ren School of Environment Engineering Yellow River Conservancy Technical InstituteKaifeng475004China School of Chemical Engineering Zhengzhou UniversityZhengzhou450001China School of Chemistry and Chemical Engineering Wuhan University of Science and TechnologyWuhan430081China Kaifeng Engineering Research Center for Municipal Wastewater Treatment Kaifeng475004China Henan Engineering Technology Research Center of Green Coating Materials 475004KaifengChina

The suspension state of crystals in the crystallizer is one of the important indicators for evaluating the adaptability of the *** study adopted the Euler-Eulerian two-fluid model to simulate and analyze the fluid motion of solid-liquid two-phase flow in the industrial-grade DTB crystallization kettle,as well as the phase suspension distribution of crystal *** main influencing factors investigated are:the heat transfer effect,the height of the bottom of the crystallizer,the number and position of the stirring paddle,crystal size and crystal volume *** on the research of Euler-Eulerian method to simulate fluids,the Euler-Lagrangian method was further used to simulate the motion state of particle phases with different particle sizes in the *** was found that the designed DTB crystallizer has good recycle mixing *** particles can be mixed evenly during the operation,which can fully realize the solid-liquid mixing and suspension effect of the drug under study.

关键词： Draff tube baffle(DTB)crystallizer Two-fluid model Numerical simulation Turbulence modelling

Bimetallic nanoparticles as cascade sensitizing amplifiers for low-dose and robust cancer radio-immunotherapy

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Acta Pharmaceutica Sinica B 2024年第4期14卷 1787-1800页

作者： Yupeng Wang lina Wang tao li Min Ouyang Hejian Xiong Dongfang Zhou Department of Ultrasonic Diagnosis Zhujiang HospitalKey Laboratory of Mental Health of the Ministry of EducationNMPA Key Laboratory for Research and Evaluation of Drug Metabolism&Guangdong Provincial Key Laboratory of New Drug ScreeningSchool of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China Testing and Analysis Center Hebei Normal UniversityShijiazhuang 050024China Department of Mechanical Engineering The University of Texas at DallasRichardsonTX 75080USA

Radiotherapy(RT)is one of the most feasible and routinely used therapeutic modalities for treating malignant *** particular,immune responses triggered by RT,known as radio-immunotherapy,can partially inhibit the growth of distantly spreading tumors and recurrent ***-ever,the safety and efficacy of radio-immunotherapy is impeded by the radio-resistance and poor immu-nogenicity of ***,we report oxaliplatin(IV)-iron bimetallic nanoparticles(OXA/Fe NPs)as cascade sensitizing amplifiers for low-dose and robust *** OXA/Fe NPs exhibit tumor-specific accumulation and activation of OXA(I)and Fe^(2+)in response to the reductive and acidic microenvironment within tumor *** cascade reactions of the released metallic drugs can sensitize RT by inducing DNA damage,increasing ROS and O_(2) levels,and amplifying the immunogenic cell death(ICD)effect after RT to facilitate potent immune *** a result,OXA/Fe NPs-based low-dose RT triggered a robust immune response and inhibited the distant and metastatic tumors effectively by a strong abscopal ***,a long-term immunological memory effect to protect mice from tumor rechal-lenging is ***,the bimetallic NPs-based cascade sensitizing amplifier system offers an effi-cient radio-immunotherapy regimen that addresses the key challenges.

关键词： Bimetallic nanoparticles Radio-immunotherapy Cascade sensitizing amplifier,Oxaliplatin Fenton-typeHaber-Weiss reaction Radiosensitization Immunogenic cell death Radio-resistance

Azacitidine maintenance therapy for blastic plasmacytoid dendritic cell neoplasm allograft: A case report

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World Journal of Clinical Cases 2024年第1期12卷 136-141页

作者： li-li tao Hui-Ting Wen Zi-Yi Wang Juan Cheng li Zhao Department of Hematology The First Clinical Medical CollegeLanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Hematology The First Hospital of Lanzhou UniversityLanzhou 730000Gansu ProvinceChina

BACKGROUND Blastic plasmacytoid dendritic cell neoplasm(BPDCN)is a rare,highly invasive malignant *** is no universally accepted standard of care because of its rarity and the dearth of prospective *** is still challenging for some patients to achieve persistent clinical remission or cure,despite the success of allogeneic hematopoietic stem cell transplantation(allo-HSCT),indicating that there is still a significant recurrence *** report a case of prevention of BPDCN allograft recurrence by azacitidine maintenance therapy and review the relevant *** SUMMARY We report a 41-year-old man with BPDCN who was admitted to hospital due to skin sclerosis for>5 mo’*** was diagnosed by combined clinical assessment and laboratory *** diagnosis,the patients underwent induction consolidation chemotherapy to achieve the first complete remission,followed by bridging ***-transplantation,azacitidine(75 mg/m2 for 7 d)was administered as maintenance therapy,with repeat administration every 4–6 wk and appropriate extension of the chemotherapy *** 10 cycles,the patient has been disease free for 26 mo after *** assessments of bone marrow morphology,minimal residual disease,full donor chimerism,Epstein–Barr virus,and cytomegalovirus all yielded normal results with no abnormalities *** Azacitidine may be a safe and effective maintenance treatment for BPDCN following transplantation because there were no overt adverse events during the course of treatment.

关键词： Blastic plasmacytoid dendritic cell neoplasm Azacitidine Allogeneic hematopoietic stem cell transplantation Maintenance therapy Case report

Bioinspired Stretchable MXene Deformation-Insensitive Hydrogel Temperature Sensors for Plant and Skin Electronics

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Research 2024年第1期2023卷 389-401页

作者： Jun Wu Yinghui li Shengshun Duan Zhehan Wang Xu Jing Yucheng lin Di Zhu Wei Lei Qiongfeng Shi li tao Joint International Research Laboratory of Information Display and Visualization School of Electronic Science and EngineeringSoutheast UniversityNanjingJiangsu 210096China School of Materials Science and Engineering Southeast UniversityNanjingJiangsu 210096China Center of 2D Materials and Devices Southeast UniversityNanjingJiangsu 210096China

Temperature sensing is of high value in the wearable healthcare,robotics/prosthesis,and noncontact physiological ***,the common mechanic deformation,including pressing,bending,and stretching,usually causes undesirable feature size changes to the inner conductive network distribution of temperature sensors,which seriously influences the ***,inspired by the transient receptor potential mechanism of biological thermoreceptors that could work precisely under various skin contortions,we propose an MXene/Clay/poly(N-isopropylacrylamide)(PNIPAM)(MCP)hydrogel with high stretchability,spike response,and deformation *** dynamic spike response is triggered by the inner conductive network transformation from the 3-dimensional structure to the 2-dimensional surface after water being discharged at the threshold *** water discharge is solely determined by the thermosensitivity of PNIPAM,which is free from mechanical deformation,so the MCP hydrogels can perform precise threshold temperature(32℃)sensing under various deformation conditions,i.e.,pressing and 15%*** a proof of concept,we demonstrated the applications in plant electronics for the real-time surface temperature monitoring and skin electronics for communicating between human and *** research opens venues for the accurate temperature-threshold sensation on the complicated surface and mechanical conditions.

关键词： stretching proof precise

Theory and practice of hull dynamic deformation law and heading angle transfer error correction

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Journal of Ocean Engineering and Science 2024年第2期9卷 191-198页

作者： Yepin Qu Jianqiang liu Yuhai Lyu Chaoran Zhang tao li Naval Research Institute Shanghai 200436PR China

In order to meet the demand of high-precision heading angle transmission in the transfer alignment of inertial navigation system on moving base,the analytical function relationship between the hull deforma-tion and the turning angular velocity and angular acceleration was derived by using the classical beam theory based on the analysis of the equivalent load exerted by the hydrodynamic force and inertia force on the hull structure during the turning process under the combined action of the steering rudder mo-ment and wave *** objective law between the angular motion and the azimuth deformation angle of the hull under the combined action of maneuvering and sea waves was ***,the correc-tion coefficients were determined according to the left turn and right turn motions of the hull by using the measured data of the ship in the sea trial during the S-shape maneuvering navigation,and the az-imuth deformation angle correction was *** results indicated that the application of the Qu’s bending deformation correction formula could greatly reduce the influence of the hull flexural deforma-tion on the heading angle accuracy,meet the needs of high-precision heading angle transmission,and fully verify the correctness of the hull azimuth deformation law and the heading angle transmission er-ror correction *** theory and method provided technical support for establishing high-precision distributed digital reference in the field of transfer alignment of inertial navigation on moving base and the application of heading angle transfer of other shipborne equipment.

关键词： Hull deformation Hull girder Heading angle Alignment on moving Base Transfer alignment Error correction

Cobalt-catalyzed deoxygenative borylation of diaryl ketones

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Chinese Chemical Letters 2024年第3期35卷 277-281页

作者： Longqing liu Bing Zhang Yu liu Jinbo Zhao tao li Wanxiang Zhao College of Chemistry and life Science Changchun University of TechnologyChangchun 130012China State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China

Geminal diboronates and diarylmethyl boronates are versatile building blocks in synthetic *** here reported a highly efficient approach for the synthesis of gem-bisborylalkanes and diarylmethyl boronates via cobalt-catalyzed deoxygenative borylation of diaryl *** borylation protocol is compatible with a broad range of functionalized aryl groups,providing access to a wide array of boronic *** resulting boronic esters can be further transformed to various cross-coupling products and TPEs that represent important structural motifs in organic chemistry and materials science.

关键词： Bisborylalkanes Cobalt Deoxygenative borylation Ketones