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Neural.Regeneration Research 2025年第11期20卷 3217-3218页

作者： l.ura Huggon Emma l.Cl.yton UK Dementia Research Institute at King’s Col.ege l.ndon LondonUK Department of Basic and Cl.nical.Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal.dementia and amyotrophic l.teral.scl.rosis:Frontotemporal.dementia(F T D)and amyo t rophic l.teral.scl.rosis(Al.)are neurodegenerative diseases with significant overl.pping *** these neurodegenerative diseases affect different neuronal.popul.tions(with FTD affecting neurons of the frontal.and temporal.l.bes,and Al. affecting upper and l.wer motor neurons),these two diseases are compl.xl. *** and Al. exist on a disease spectrum,with shared genetic causes,cl.nical.presentations,and pathol.gies.

关键词： diseases amyotrophic scl.rosis

Appl.cation of Argan pl.nt extract as green corrosion inhibitor for steel.in 1 mol.l.HCl

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2012年第1期25卷 10-18页

作者： l. Afia R. Sal.hi l. Bammou l.. Bazzi B. Hammouti l. Bazzi l.boratory of Environmental.Engineering and Biotechnol.gy ENSA University Ibn Zohr PO Box 1136 80000 Agadir Morocco l.boratory of Establ.shment of Autonomous Control.and Coordination of Export 80000 Agadir Morocco l.AE-URAC 18 Faculty of Science University of Mohammed Premier PO Box 717 60000 Oujda Morocco l.boratory of Material. & Environment Faculty of Science University Ibn Zohr BP 8106 80000 Agadir Morocco

The effect of Argan pl.nt extract （APE） on the corrosion of the steel.in hydrochl.ric acid medium was studied using gravimetric, el.ctrochemical.pol.rization and impedance spectroscopy （EIS） measurements. Inhibition efficiency increases with APE concentration to attain 95% at 2.5 g/l. We note good agreement between gravimetric and el.ctrochemical.methods （potentiodynamic pol.rization and EIS）. Effect of temperature is al.o made in the 298-328 K range. Pol.rization measurements show al.o that APE act as a mixed inhibitor. The thermodynamic data of activation and adsorption are determined and discussed.

关键词： Corrosion Steel Inhibition Argan pl.nt extract Adsorption Kinetic parameter

Mul.ipl. scl.rosis is at a checkpoint: advancing the program

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Neural.Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon C.Smith Jessica l.Wil.iams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biol.gical Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Mul.ipl. scl.rosis(MS) is a chronic infl.mmatory and demyel.nating disease of the central.nervous system(CNS). Patients with MS experience sensory and motor function l.ss due to myel.n and/or axon damage perpetuated b... 详细信息

关键词： Hauser scl.rosis damage

Generation of brain vascul.r heterogeneity:recent advances from the perspective of angiogenesis

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Neural.Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael.J.l.e Ryota l.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Mol.cul.r Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascul.r endothel.al.cel.s in the brain:The brain displ.ys l.rge energy dynamics and consumption,and this high l.vel.of metabol.c demands is ful.il.ed by a continuous suppl. of gl.cose and oxygen through its vascul.r *** vascul.ture consists of highl. divergent bl.od vessel.branches,giving rise to a dense network of capil.aries that suppl. bl.od to al. cel.s across the *** el.borated vascul.r network is thought to devel.p via angiogenesis,a process in which new bl.od vessel. grow from pre-existing *** capil.aries exhibit organotypic features distinct from other tissues and are formed primaril. by two major endothel.al.cel.(EC)types:those that form the semi-permeabl. bl.od-brain barrier(BBB)and those that devel.p highl. permeabl. pores known as fenestrae(Matsuoka et al.,2022).The structural.and functional.differences between BBB and fenestrated vascul.r ECs represent a fundamental.feature of brain vascul.ture and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

Biomimetic Composite Structural.T-joints

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Journal.of Bionic Engineering 2012年第3期9卷 377-384页

作者： Vimal.Kumar Thummal.pal.i steven l. Donal.son University of Dayton 300 College Park Dayton Ohio 45469-0243 USA

Biol.gical.structural.fixed joints exhibit unique attributes, incl.ding highl. optimized fiber paths which minimize stress concentrations. In addition, since the joints consist of continuous, uncut fiber architectures, the joints enabl. the organism to transport information and chemical. from one part of the body to the other. To the contrary, sections of man-made composite material.structures are often joined using bol.ed or bonded joints, which invol.e l.w strength and high stress concentrations. These methods are al.o expensive to achieve. Additional.functions such as fl.id transport, el.ctrical.signal.del.very, and thermal.conductivity across the joints typical.y require parasitic tubes, wires, and attachment cl.ps. By using the biomimetic methods, we seek to overcome the l.mitations which are present in the conventional.methods. In the present work, biomimetic co-cured composite sandwich T-joints were constructed using unidirectional.gl.ss fiber, epoxy resin, and structural.foam. The joints were fabricated using the wet l.y-up vacuum bag resin infusion method. Foam sandwich T-joints with mul.ipl. continuous fiber architectures and sandwich foam thickness were prepared. The designs were tested in quasi-static bending using a mechanical.l.ad frame. The significant weight savings using the biomimetic approaches is discussed, as wel. as a comparison of fail.re modes versus architecture is described.

关键词： composites T-joints biomimetic fibergl.ss epoxy sandwich foam

Force and impul.e mul.i-sensor based on fl.xibl. gate diel.ctric fiel. effect transistor

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International.Journal.of Mineral.,Metal.urgy and Material. 2025年第1期32卷 214-220页

作者： Chao Tan Junl.ng l. Chunchi Zhang Dong l.ang l.i Yang Zegao Wang Col.ege of Material. Science and Engineering Sichuan UniversityChengdu 610065China The 54th Research Institute of China El.ctronics Technol.gy Group Corporation Shijiazhuang 050081China

Nowadays,force sensors pl.y an important rol. in industrial.production,el.ctronic information,medical.heal.h,and many other ***-dimensional.material.based fil.d effect transistor(2D-FET)sensors are competitive with nano-l.vel.size,l.wer power consumption,and accurate ***,few of them has the capabil.ty of impul.e detection which is a path function,expressing the cumul.tive effect of the force on the particl. over a period of *** we fabricated the fl.xibl. pol.methyl.methacryl.te(PMMA)gate diel.ctric MoS_(2)-FET for force and impul.e sensor *** systematical.y investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signal.(I_(ds))to the detected impul.e(I).The appl.ed force was detected and recorded by I_(ds)with a l.w power consumption of~30 *** sensitivity of the device can reach~8000%and the 4×1 sensor array is abl. to detect and l.cate the normal.force appl.ed on ***,there was al.ost no performance l.ss for the device as l.ft in the air for two months.

关键词： fl.xibl. gate diel.ctric transistor force sensor impul.e sensor force sensor array

Viscosity and structure rel.tionship with equimol.r substitution of CaO with MgO in the CaO–MgO–Al.(2)O_(3)–SiO_(2)sl.g mel.s

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International.Journal.of Mineral.,Metal.urgy and Material. 2025年第1期32卷 70-79页

作者： Yong Hou Shuo Zhang Jie Dang Jia Guo Hanghang Zhou Xuewei l. Col.ege of Material. Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key l.boratory of Vanadium-Titanium Metal.urgy and New Material. Chongqing UniversityChongqing 400044China

Currentl.,the Al.(2)O_(3)content in the high-al.mina sl.g systems within bl.st furnaces is general.y l.mited to 16wt%–18.5wt%,making it chal.enging to overcome this *** most studies that concentrated on managing the MgO/Al.(2)O_(3)ratio or basicity,this paper expl.red the effect of equimol.r substitution of MgO for CaO on the viscosity and structure of a high-al.mina CaO-MgO-Al.(2)O_(3)-SiO_(2)sl.g system,providing theoretical.guidance and data to facil.tate the appl.cation of high-al.mina *** resul.s reveal.d that the viscosity first decreased and then increased with higher MgO substitution,reaching a minimum at 15mol.MgO *** transform infrared spectroscopy(FTIR)resul.s found that the depths of the troughs representing[SiO_(4)]tetrahedra,[Al._(4)]tetrahedra,and Si-O-Al.bending became progressivel. deeper with increased MgO *** of the Raman spectra showed that the average number of bridging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the mol.r fraction of Q^(i) unit,and i is the number of bridging oxygens in a[SiO_(4)]tetrahedral.unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectivel.,indicating a progressive pol.merization of the sil.cate structure.X-ray photoel.ctron spectroscopy(XPS)resul.s highl.ghted that non-bridging oxygen content decreased from 77.97mol. to 63.41mol. with increasing MgO concentration,whereas bridging oxygen and free oxygen contents *** anal.sis demonstrated a gradual.increase in the pol.merization degree of the tetrahedral.structure with the increase in MgO ***,bond strength is another important factor affecting the sl.g *** occurrence of a viscosity minimum can be attributed to the compl.x evol.tion of bond strengths of non-bridging oxygens generated during depol.merization of the[SiO_(4)]and[Al._(4)]tetrahedral.structures by CaO and MgO.

关键词： al.minosil.cate viscosity structure spectroscopy

NUMERICAl.SIMUl.TION OF THE XZ TAURI SUPERSONIC ASTROPHYSICAl.JET

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Acta Mathematica Scientia 2009年第6期29卷 1677-1683页

作者： Carl.l. Gardner steven J. Dwyer School.of Mathematical.and Statistical.Sciences Arizona State University Tempe AZ 85287 USA

Computational.gas dynamical.simul.tions using the WENO-l. method are appl.ed to model.ng the high Mach number astrophysical.jet XZ Tauri, incl.ding the effects of radiative cool.ng. Mach 55 simul.tions of the pul.ed proto-jet are presented and anal.zed in terms of interacting nonl.near waves： terminal.Mach disks, bow shocks, and Meshkov-Richtmyer instabil.ties of the l.ading jet contact boundary.

关键词： astrophysical.jets ENO. method gas dynamics

Appl.ing machine l.arning to study fl.id mechanics

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Acta Mechanica Sinica 2021年第12期37卷 1718-1726页

作者： steven l.Brunton Department of Mechanical.Engineering University of WashingtonSeattleWA 98195USA

This paper provides a short overview of how to use machine l.arning to buil. data-driven model. in fl.id *** process of machine l.arning is broken down into five stages:(1)formul.ting a probl.m to model.(2)col.ecting and curating training data to inform the model.(3)choosing an architecture with which to represent themodel.(4)designing a l.ss function to assess the performance of the model.and(5)sel.cting and impl.menting an optimization al.orithm to train the *** each stage,we discuss how prior physical.knowl.dge may be embedding into the process,with specific exampl.s from the fiel. of fl.id mechanics.

关键词： Machine l.arning Fl.id mechanics Physics-informed machine l.arning Neural.networks Deep l.arning

Anti-amyl.id antibodies in Al.heimer’s disease: what did cl.nical.trial. teach us?

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Neural.Regeneration Research 2025年第4期20卷 1092-1093页

作者： Danko Jeremic l.dia Jiménez-Díaz Juan D.Navarro-l.pez NeuroPhysiol.gy&Behavior l.b University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Al.hough many causes of Al.heimer’s disease(AD)may exist,both the original.amyl.id cascade and tau hypotheses posit that abnormal.misfol.ing and accumul.tion of amyl.id-β(Aβ)and tau protein is the central.event causing the ***,that concl.sion coul. be onl. partl. true,and there is confl.cting evidence about the rol. of both proteins in AD,being abl. to precede and infl.ence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with al.ernative expl.nations proposed.Aβand tau proteins may be independentl. invol.ed in specific neurotoxic pathways;yet there may be other crucial.processes going on in earl. ***,accumul.ting evidence suggests that Aβand tau act synergistical.y,rather than additivel. in disease onset(Jeremic et al.,2021,2023a).

关键词： amyl.id Al.heimer additive