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Discrepancies between the responses to skin prick test to food and respiratory antigens in two subtypes of patients with irritable bowel syndrome

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World Journal of Gastroenterology 2008年第19期14卷 3044-3048页

作者： Rosa ls soares Hamilton N Figueiredo Jose M santos Rita F Oliveira Raquel l Godoy Felipe AP Mendona Internal Medicine Department Faculty of Medicine-Federal Fluminense University Internal Medicine Department Faculty of MedicineFederal Fluminense University Medical school of Universitary Hospital Antonio Pedro Federal Fluminense University Medical school of Faculty of Medicine Federal Fluminense University

AIM:To compare the response to skin prick tests (sPTs) to food antigens (FAs) and inhalant allergens (ias) in patients with two subtypes of irritable bowel syndrome (IBs) and healthy controls. METHODs:We compared the results of sPTs for ias and FAs in 87 volunteers divided into three groups:diarrhea predominant IBs (D-IBs) GroupⅠ(n = 19), constipation predominant IBs (C-IBs) Group Ⅱ (n = 17), and normal controls Group Ⅲ (n = 51). REsUlTs:Of the 285 tests (171 for FAs and 114 for ias) performed in GroupⅠwe obtained 45 (26.3%) positive responses for FA and 23 (20.1%) for ia. Of the 153 tests for FA in Group Ⅱ, we obtained 66 (20.1%) positive responses, and of the 102 tests for ia, we obtained 20 (19.6%) positive responses. Of the 459 tests for FA performed in Group Ⅲ, we obtained 39 (84%) positive responses, and of the 306 for ia, we obtained 52 (16.9%) positive responses. The numbers of positive responses were not significantly different between the three groups, but in the D-IBs group, the number of sPTFA responses differed significantly from those for the other two groups (P lUsION:Despite the small number of cases studied, the higher reactivity to FAs in GroupⅠcompared to Groups Ⅱ and Ⅲ adds new information, and suggests the presence of a possible alteration in intestinal epithelial function.

关键词： Atopy Constipation Diarrhea Foodintolerance Irritable bowel syndrome skin prick test

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synthesis,structural and Photophysical Properties of Gd_(2)O_(3):Eu^(3+)Nanostructures Prepared by a Microwave sintering Process

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Advances in Chemical Engineering and science 2014年第3期4卷 374-388页

作者： Ana P.de Moura larissa H.Oliveira Icamira C.Nogueira Paula F.s.Pereira Maximo s.li Elson longo Jose A.Varela Ieda l.V.Rosa Chemistry Institute State University of Sao Paulo-UNESPAraraquaraBrazil Department of Engineering Materials Federal University of Sao CarlosSao CarlosBrazil Institute of Physics of sao Carlos USPSao CarlosBrazil Department of Chemistry Federal University of Sao CarlosSao CarlosBrazil

In this paper, we report the obtention of gadolinium oxide doped with europium (Gd2O3:Eu+3) by thermal decomposition of the Gd(OH)3:Eu3+ precursor prepared by the microwave assisted hydrothermal method. These systems were analyzed by thermalgravimetric analyses (TGA/DTA), X-ray diffraction (XRD), structural Rietveld refinement method, fourrier transmission infrared absorbance spectroscopy (FT-IR), field emission scanning electron microscopy (FE-sEM) and photoluminescence (Pl) measurement. XRD patterns, Rietveld refinement analysis and FT-IR confirmed that the Gd(OH)3:Eu3+ precursor crystallize in a hexagonal structure and space group P6/m, while the Gd2O3:Eu3+ powders annealed in range of 500°C and 700°C crystallized in a cubic structure with space group ia-3. FE-sEM images showed that Gd(OH)3:Eu3+ precursor and Gd2O3:Eu3+ are composed by aggregated and polydispersed particles structured as nanorods-like morphology. The excitation spectra consisted of an intense broad band with a maximum at 263 nm and the Eu3+ ions can be excitated via matrix. The emission spectra presented the characteristics transitions of the Eu3+ ion, whose main emission, , is observed at 612 nm. The photophysical properties indicated that the microwave sintering treatment favored the Eu3+ ions connected to the O-Gd linkages in the Gd2O3 matrix. Also, the emission in the Gd2O3:Eu3+ comes from the energy transfered from the Gd-O linkages to the clusters in the crystalline structure.

关键词： Gadolinuim Oxide Europium luminescence Nanorods

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Hybrid Rice seed Treatment with Pesticides Improves Its Physiological Quality and Performance

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American Journal of Plant sciences 2015年第14期6卷 2405-2411页

作者： Andréia da silva Almeida César Iván suárez Castellanos Cristiane Deuner Adilson Jauer Thais Ongaratto de Camargo Cristian Troyjack Geri Eduardo Meneglhelo Francisco Amaral Villela Paulo Dejalma Zimmer lilian Madruga de Tunes PPG em Ciência e Tecnologia de sementes Universidade Federal de Pelotas Pelotas Brazil syngenta Crop Protection Pelotas Brazil

Pathogens in the soil or transmitted by seeds can reduce the stand of plants, affecting the yield of the crop. Furthermore, in the case of rice, the low temperature is a limiting factor in culture. The treatment of seeds with insecticides is an alternative to reduce the damage caused by pests incidents during the early stages of plant development and in some cases, may assist in the germination of seeds exposed to low temperatures. In this sense, the objective of this study was to evaluate the influence of seed treatment with insecticides in the physiological quality and yield of hybrid rice seeds, cv. Inov Cl. For this, three experiments were conducted with treated seeds in different doses of thiamethoxam + lambda-cyhalothrin and fipronil totaling seven treatments, including the control (no product). In the first experiment, it was determined seed germination to 10°C, 13°C, 16°C, 20°C and 25°C. In the second experiment, it was assessed seed vigor through accelerated aging, cold test and emergency field. The third experiment was carried out into the field to observe the number of panicles m-2 and crop yield. It is concluded that treatment of hybrid rice seeds, cv. Inov Cl with thiamethoxam + lambda-cyhalothrin and fipronil increases the germination percentage of seed and early seedling performance. Treatment of hybrid rice seeds, cv. Inov Cl with thiamethoxam + lambda-cyhalothrin provides greater germination and early seedling performance compared to treatment with fipronil. Treatment of hybrid rice seeds, cv. Inov Cl with thiamethoxam + lambda-cyhalothrin in dosages of 500 ml 100 kg-11 of seeds or 500 ml 45 kg-1 of seeds increases grain yield.

关键词： Oryza sativa l. Vigor Yield Potential

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REVIEW OF PARTIClE PHYsICs

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Chinese Physics C 2014年第9期38卷 1-4页

作者： K.A.Olive K.Agashe C.Amsler M.Antonelli J.-F.Arguin D.M.Asner H.Baer H.R.Band R.M.Barnett T.Basaglia C.W.Bauer J.J.Beatty V.I.Belousov J.Beringer G.Bernardi s.Bethke H.Bichsel O.Biebe E.Blucher s.Blusk G.Brooijmans O.Buchmueller V.Burkert M.A.Bychkov R.N.Cahn M.Carena A.Ceccucci A.Cerr D.Chakraborty M.-C.Chen R.s.Chivukula K.Copic G.Cowan O.Dahl G.D'Ambrosio T.Damour D.de Florian A.de Gouvea T.DeGrand P.de Jong G.Dissertor B.A.Dobrescu M.Doser M.Drees H.K.Dreiner D.A.Edwards s.Eidelman J.Erler V.V.Ezhela W.Fetscher B.D.Fields B.Foster A.Freitas T.K.Gaisser H.Gallagher l.Garren H.-J.Gerber G.Gerbier T.Gershon T.Gherghetta s.Golwala M.Goodman C.Grab A.V.Gritsan C.Grojean D.E.Groom M.Grnewald A.Gurtu T.Gutsche H.E.Haber K.Hagiwara C.Hanhart s.Hashimoto Y.Hayato K.G.Hayes M.Heffner B.Heltsley J.J.Hernandez-Rey K.Hikasa A.Hocker J.Holder A.Holtkamp J.Huston J.D.Jackson K.F.Johnson T.Junk M.Kado D.Karlen U.F.Katz s.R.Klein E.Klempt R.V.Kowalewski F.Krauss M.Kreps B.Krusche Yu.V.Kuyanov Y.Kwon O.lahav J.laiho P.langacker A.liddle Z.ligeti C.-J.lin T.M.liss l.littenberg K.s.lugovsky s.B.lugovsky F.Maltoni T.Mannel A.V.Manohar W.J.Marciano A.D.Martin A.Masoni J.Matthews D.Milstead P.Molaro K.Monig F.Moortgat M.J.Mortonson H.Murayama K.Nakamura M.Narain P.Nason s.Navas M.Neubert P.Nevski Y.Nir l.Pape J.Parsons C.Patrignani J.A.Peacock M.Pennington s.T.Petcov Kavli IPMU A.Piepke A.Pomarol A.Quadt s.Raby J.Rademacker G.Raffel B.N.Ratcliff P.Richardson A.Ringwald s.Roesler s.Rolli A.Romaniouk l.J.Rosenberg J l.Rosner G.Rybka C.T.sachrajda Y.sakai G.P.salam s.sarkar F.sauli O.schneider K.scholberg D.scott V.sharma s.R.sharpe M.silari T.sjostrand P.skands J.G.smith G.F.smoot s.spanier H.spieler C.spiering A.stahl T.stanev s.l.stone T.sumiyoshi M.J.syphers F.Takahashi M.Tanabashi J.Terning l.Tiator M.Titov N.P.Tkachenko N.A.Tornqvist D.Tovey G.Valencia G.Venanzoni M.G.Vincter P.Vogel A.Vogt s.P.Wakely W.Walkowiak C.W.Walter D.R.Ward G.Weiglein D.H.Weinberg E.J.Weinberg M.White l.R.Wiencke C.G.Wohl l.Wolfenstein J.Womersley C.l. University of Minnesota School of Physics and Astronomy116 Church St.S.E.MinneapolisMN 55455USA University of Maryland Department of PhysicsCollege ParkMD 20742-4111USA Albert Einstein Center for Fundamental Physics Universitat BernCH-3012 BernSwitzerland lab.Nazionali di Frascati dell'INFN CP 13via E.Fermi40I-00044 Frascati(Roma)Italy Departement de physique Universite de MontrealC.P.6128succ.centre-villeMontreal(Quebec) H3C 3J7Canada Pacific Northwest National laboratory 902 Battelle BoulevardRichlandWA 99352USA Department of Physics and Astronomy University of OklahomaNormanOK 73019USA Department of Physics University of WisconsinMadisonWI 53706USA Physics Division Lawrence Berkeley National Laboratory1 Cyclotron RoadBerkeleyCA 94720USA CERN European Organization for Nuclear ResearchCH-1211 Geneve 23Switzerland Department of Physics The Ohio State University191 W.Woodruff Ave.ColumbusOH 43210 COMPAs Group Institute for High Energy PhysicsRU- 142284ProtvinoRussia lPNHE IN2P3-CNRS et Universites de Paris 6 et 7F-75252 ParisFrance Max-Planck-Institute of Physics 80805 MunichGermany Department of Physics University of WashingtonSeattleWA 98195USA ludwig-Maximilians-Universitat Fakultdt für PhysikSchellingstr.4D-80799 MünchenGermany Enrico Fermi Institute and Department of Physics University of ChicagoChicagoIL 60637-1433USA Department of Physics Syracuse UniversitySyracuseNY13244USA Department of Physics Columbia University538 W.120th StreetNew YorkNY10027 USA High Energy Physics Group Blackett LaboratoryImperial CollegePrince Consort RoadLondon SW7 2AZUK Jefferson lab 12000 Jefferson Ave.Newport NewsVA 23606USA Department of Physics University of VirginiaPO Box 400714CharlottesvilleVA 22904USA Fermi National Accelerator laboratory P.O.Box 500BataviaIL 60510USA Kavli Institute for Cosmological Physics University of ChicagoChicagoIL 60637-1433USA Department of Physics and Astronomy University of SussexFalmerBrighton BN1 9QHUK Department o

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,283 new measurements from 899 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as heavy neutrinos, supersymmetric and technicolor particles, axions, dark photons, etc. All the particle properties and search limits are listed in summary Tables. We also give numerous tables, figures, formulae, and reviews of topics such as supersymmetry, Extra Dimensions, Particle Detectors, Probability, and statistics. Among the 112 reviews are many that are new or heavily revised including those on： Dark Energy, Higgs Boson Physics, Electroweak Model, Neutrino Cross section Measurements, Monte Carlo Neutrino Generators, Top Quark, Dark Matter, Dynamical Electroweak symmetry Breaking, Accelerator Physics of Colliders, High-Energy Collider Parameters, Big Bang Nucleosynthesis, Astrophysical Constants and Cosmological Parameters. A booklet is available containing the summary Tables and abbreviated versions of some of the other sections of this full Review. All tables, listings, and reviews （and errata） are also available on the Particle Data Group website： http ：//pdg. lbl. gov.

关键词： REVIEW OF PARTIClE PHYsICs

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Rational design of oral drugs targeting mucosa delivery with gut organoid platforms

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Bioactive Materials 2023年第12期30卷 116-128页

作者： Tianjian Tong Yijun Qi Derrick Rollins luke D.Bussiere Debarpan Dhar Cathy l.Miller Chenxu Yu Qun Wang Department of Agricultural Biosystem and Engineering Iowa State UniversityAmesIAUSA Department of Chemical and Biological Engineering Iowa State UniversityAmesIAUSA Department of Veterinary Microbiology and Preventive Medicine College of Veterinary MedicineIowa State UniversityAmesIAUSA Interdepartmental Microbiology Program Iowa State UniversityAmesIAUSA Department of statistics Iowa State UniversityAmesIAUSA

Effective oral drugs and vaccines require high delivery efficiency across the gastrointestinal epithelia and protection of medically effective payloads(i.e.,immunogens)against gastric *** this study,hollowed nanocarriers(NCs:silica nanospheres and gold nanocages)with poly-l-lysine(Pll)coating and mammalian orthoreovirus cell attachment proteinσ1 functionalization(NC-Pll-σ1)were explored as functional oral drug delivery vehicles(ODDVs).The transport of these ODDVs to mucosal lymphoid tissues could be facilitated by microfold cells(M-cells)mediated transcytosis(viaσ1-α2–3-linked sialic acids adherence)across gastrointestinal *** coating provided protection and slow-release of rhodamine 6 G(R6G),a model *** transport effectiveness of these ODDVs was tested on intestinal organoid monolayers in *** compared with other experimental groups,the fully functionalized ODDV system(with Pll-σ1)demonstrated two significant advantages:a significantly higher transport efficiency(198%over blank control at 48 h);and protection of payloads which led to both better transport efficiency and extended-release of payloads(61%over uncoated carriers at 48 h).In addition,it was shown that the M cell presence in intestinal organoid monolayers(modulated by Rank l stimulation)was a determining factor on the transport efficiency of the ODDVs:more M-cells(induced by higher Rank l)in the organoid monolayers led to higher transport efficiency for ODDV-delivered model payload(R6G).The fully functionalized ODDVs showed great potential as effective oral delivery vehicles for drugs and vaccines.

关键词： Oral drug delivery vehicles Organoids Biomimetic virus sigma 1 protein Gold and silica nanoparticles

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sARs-CoV-2 infection in free-ranging white-tailed deer

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四川生理科学杂志 2021年第10期43卷 1834-1834页

作者： Vanessa l Hale Veterinary Preventive Medicine The Ohio State University College of Veterinary Medicine Columbus OH 43210 USA Cleveland Metroparks Zoo Cleveland OH 44109 USA Center for Food Animal Health The Ohio State University College of Food Agriculture and Environmental Sciences Wooster OH 44691 USA The Ohio state University College of Veterinary Medicine Columbus OH 43210 USA Cleveland Metroparks Cleveland OH 44144 USA Veterinary Clinical sciences The Ohio State University College of Veterinary Medicine Columbus OH 43210 USA Ohio Wildlife Center Powell OH 43065 USA National Veterinary services laboratories Animal and Plant Health Inspection Service United States Department of Agriculture Ames IA 50010 USA Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD 20892 USA Infectious Diseases Institute The Ohio State University Columbus OH 43210 USA

Humans have infected a wide range of animals with sARs-CoV-2 viruses1-5,but the establishment of a new natural animal reservoir has not been ***,we document that free-ranging white-tailed deer(Odocoileus virginianus)are highly susceptible to infection with sARs-CoV-2 virus,are exposed to a range of viral diversity from humans,and are capable of sustaining transmission in ***-CoV-2 virus was detected by rRT-PCR in more than one-third(129/360,35.8%)of nasal swabs obtained from Odocoileus virginianus in northeast Ohio(UsA)during January-March *** in 6 locations were infected with 3 sARs-CoV-2 lineages(B.1.2,B.1.582,B.1.596).The B.1.2 viruses,dominant in humans in Ohio at the time,infected deer in four *** deer-to-deer transmission of B.1.2,B.1.582,and B.1.596 viruses was observed,allowing the virus to acquire amino acid substitutions in the spike protein(including the receptor-binding domain)and ORF1 that are infrequently seen in humans.

关键词： white infection free

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Role of Calcium-Independent Phospholipase A2 V ia in Mediating Neurological Disorder and Cancer

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Transactions of Tianjin University 2017年第1期23卷 1-10页

作者： Chang Y. Chung Yu shi Austin R. surendranath Nasir Jalal Janak l. Pathak selvaraj subramaniyam school of Pharmaceutical science and Technology Tianjin University Tianjin 300072 China

Calcium-independent phospholipase A2 (iPlA2) belongs to the group VI family of phospholipase superfamily (PlA2) that catalyses the hydrolysis of glycerophospholipids at the sn-2 ester bond, producing unesterified fatt... 详细信息

Calcium-independent phospholipase Asub>2sub> (iPlAsub>2sub>) belongs to the group VI family of phospholipase superfamily (PlAsub>2sub>) that catalyses the hydrolysis of glycerophospholipids at the sn-2 ester bond, producing unesterified fatty acids and 2-lysophospholipids. Research interests on iPlAsub>2sub> have not been as significant as those on secretary PlAsub>2sub> and cytosolic PlAsub>2sub>. However, more efforts have been made recently on understanding the expression, regulation and biological function of iPlAsub>2sub>. iPlAsub>2sub> plays important roles in several biological processes, including signal transduction, phospholipid remodelling, eicosanoid formation, cell proliferation, cell differentiation and apoptosis. Modulation of iPlAsub>2sub> activity can have prominent effects on cellular metabolism, central nervous system and cardiovascular functions. Thus, dysregulation iPlAsub>2sub> can play a vital role in the pathogenesis of several diseases. The aim of this review is to provide the current understanding of the structure, function and regulation of group VI iPlAsub>2sub> and highlight its potential mechanisms of action in mediating several neurological disorders and cancer.

关键词： Calcium-independent phospholipase A2 Neurological disorders Memory acquisition Alzheimer’s disease Infantile neuroaxonal dystrophy Cancer

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石墨炉-原子吸收光谱法测定地质样品中的痕量镉

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光谱实验室 2010年第1期27卷 80-82页

作者：郭爱武石华陶丽萍张啟云青海省地质矿产测试应用中心西宁市盐湖巷15号810008

地质样品经王水溶解后,MIBK萃取,选择最佳的仪器工作条件,利用石墨炉原子吸收测定地质样品中痕量镉。方法精密度(RsD,n=6)≤5.6%,检出限为0.04μg/g(进样量10μl)。方法用于测定岩石国家标准物质中的镉,结果与标准值相符。

关键词：王水石墨炉原子吸收光谱法地质样品痕量镉

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Ideas speaking and listening activities for upper-intermediate student Teacher's book

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1984年

作者： l.Jones

来源：畅想之星图书光盘版（南... 评论

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还原型谷胱甘肽与系统性红斑狼疮患者炎性因子的相关性

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国际检验医学杂志 2018年第14期39卷 1730-1731,1735页

作者：彭可君夏洪娇刘剑荣胡建康廖永强江西萍乡市人民医院检验科江西萍乡337000

目的探讨还原型谷胱甘肽(GsH)与系统性红斑狼疮(slE)患者炎性因子的相关性。方法选取2016年1-12月在该院住院和门诊诊治的slE患者65例,根据疾病活动情况分为slE活动组和slE非活动组,另选取46位同期来该院查体的健康体检者作为对照组。检... 详细信息

目的探讨还原型谷胱甘肽(GsH)与系统性红斑狼疮(slE)患者炎性因子的相关性。方法选取2016年1-12月在该院住院和门诊诊治的slE患者65例,根据疾病活动情况分为slE活动组和slE非活动组,另选取46位同期来该院查体的健康体检者作为对照组。检测slE患者和对照组血清中GsH、高敏C-反应蛋白(hsCRP)、同型半胱氨酸(Hcy)、补体C3、C4水平;四色流式细胞术检测slE患者和健康对照组外周血CD3^+、CD4^+、CD8^+T淋巴细胞计数。结果 (1)slE活动组患者血清hsCRP、Hcy水平和CD8^+淋巴细胞计数高于非活动组和对照组,差异均有统计学意义(PsH、补体C3、C4水平和CD4^+淋巴细胞计数低于非活动组和对照组,差异均有统计学意义(PslE患者血清GsH水平与hsCRP、Hcy及CD8^+淋巴细胞计数呈负相关(r=-0.53、-0.65、-0.51,PslE患者血管内GsH水平显著降低导致氧化还原态失衡,使hsCRP和Hcy水平升高和CD4^+/CD8^+淋巴细胞倒置,形成炎性状态。

关键词：还原型谷胱甘肽 T淋巴细胞亚群炎性因子系统性红斑狼疮

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