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Advances in Atmospheric Sciences 1988年第2期5卷 181-193页

作者：倪允琪,Bette l.Otto-Bliesner,Davia D.Houghton Department of Atmospheric Sciences Nanjing University Nanjing Department of Meteorology University of wisconsin Madison WI U.S.A.53706 Department of Meteorology University of wisconsin Madison WI U.S.A.53706

An analysis is made of the effects of topography on the summer atmospheric energetics of the Northern Hemisphere in a low-resolution global spectral model. The numerical model is a global, spectral, primitive equation model with five equally spaced sigma levels in the vertical and triangular truncation at wavenumber 10 in the horizontal. The model includes comparatively full physical *** term of the energy budget equations is calculated in four specific latitudinal belts (81.11°S-11.53°S; 11.53°S-11.53°N; 11.53°N-46.24°N; 46.24癗-***癗) from a five-year simulation with mountains and a one-year simulation without mountains, respectively. Differences between them are compared and statistically tested. The results show that synoptical scale waves transport available potential energy and kinetic energy to long waves and increase conversion from available potential energy of the zonal flow to eddy's and from the eddy kinetic energy to the zonal kinetic energy in region 3 (11.53°N-46.24°N

关键词： THE EFFECTS OF TOPOGRAPHY ON THE SUMMER ATMOSPHERIC ENERGETICS OF THE NORTHERN HEMISPHERE IN A lOW-RESOlUTION GlOBAl SPECTRAl MODEl

Donor risk factors in pancreas transplantation

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World Journal of Transplantation 2020年第12期10卷 372-380页

作者： luis Muñoz-Bellvís Jaime lópez-Sánchez Department of General&Gastrointestinal Surgery Hospital Universitario de SalamancaUniversidad de SalamancaSalamanca 37007Spain Salamanca Biomedical Research Institute(IBSAl) Universidad de SalamancaSalamanca 37007Spain

The aim of the work was to analyze and expose the donor and recipient riskfactors in pancreas transplantation. In the following paper, we exposed the 2018Spanish Consensus Document on Donor and Recipient Selection Criteria forPancreas Transplantation. An assessment of the previous Selection Criteria forDonors and Recipients of Pancreas Transplantation, published in 2005 by theSpanish Pancreas Transplant Group (GETP) and the National TransplantOrganization (ONT) was performed. A literature review was performed usingCochrane library, PubMed and Google Scholar databases. Some of the followingterms were used for the literature search: “Diabetes Mellitus,” “PancreasTransplantation,” “Insulin-Secreting Cells,” “Pancreas Allograft Thrombosis,”“Allograft Pancreatitis,” “Donors’ Risk Factors,” “Recipients’ Risk Factors,”“Pancreas Allograft Rejection” and “Pancreas Allograft Survival.” After anextended search, different inclusion criteria were established. Articles anddocuments with abstracts of full text and in English or Spanish language wereselected. Subsequently, different scientific meetings took place during 2015 and2016 by the GETP. Finally, the updated criteria were published by the GETP andONT in 2018. Several risk factors have been described in pancreas transplantationthat can be divided into donor risk factors: Advanced age (> 50 years);high bodymass index (BMI) (> 30 kg/m2);cause of death (e.g., stroke);previoushyperglycemia;hyperamylasemia;cold ischemia time (greater than 8 or 12 h,depending on the type of donation);the use of vasopressors in the intensive careunit or cardiac arrest;and the macroscopic aspect of the pancreas allograft. Thefollowing are recipient risk factors: Advanced age (> 50 years);active smoking;high BMI (> 30 kg/m2);and peripheral artery disease or sensorimotorpolyneuropathy. Based on the aforementioned parameters, different selectioncriteria have been established for the recipients depending on the type of pancreastransplantation. Knowledge

关键词： Pancreas transplantation Pancreas donor Pancreas recipient Diabetes mellitus Risk factors Graft rejection

Geomimicry—liberating high-pressure research by encapsulation

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Matter and Radiation at Extremes 2022年第6期7卷 79-81页

作者： Ho-Kwang Mao Wendy l.Mao Center for High Pressure Science and Technology Advanced Research 10 Dongbeiwang West RoadHaidianBeijing 100094China Department of Geological Sciences Stanford UniversityStanfordCalifornia 94305USA

High pressures induce changes of properties and structures that could greatly impact materials science if such changes were preserved for ambient *** the geological process of diamond formation that the pressures and high-pressure phases in diamond inclusions can be preserved by the strong diamond envelope,we discuss the perspectives that such process revolutionizes high-pressure science and technology and opens a great potential for creation of functional materials with extremely favorable properties.

关键词： properties ambient process

Epigenetics,a key player of immunotherapy resistance

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Cancer Drug Resistance 2018年第4期1卷 219-229页

作者： Paul Peixoto Elodie Renaude Michaël Boyer-Guittaut Eric Hervouet UMR1098 Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et GéniqueUniversity of Bourgogne Franche-ComtéINSERMEFS Bourgogne Franche-ComtéBesançon F-25000France EPIGENEXP platform University of Bourgogne Franche-ComtéBesançon F-25000France DImaCell platform University of Bourgogne Franche-ComtéBesançon F-25000France

In 2018,the Nobel Prize in medicine was awarded to James *** and Tasuku Honjo for their work on the description of immune checkpoint inhibitors which contributed to the development of new anti-cancer ***,although these new therapeutic strategies,which are designed to limit immune escape of cancer cells,have been used or tested successfully in many different cancers,a large proportion of patients have been described to resist and not respond to these new *** new incoming challenge is now therefore to overcome these resistance and new recent data presented epigenetic modifications as promising targets to restore anti-tumor ***,both DNA methylation and post-translational histone modifications have been described to regulate immune checkpoint inhibitor expression,tumor-associated antigen presentation or cancer cell editing by the immune system and therefore establishing epigenetic drugs as a potential complement to immunotherapies to improve their efficiency.

关键词： Epigenetics DNA methylation drug resistance immunotherapy programed cell death 1 programed cell death ligand 1 cancer

Theoretical Study of Electron Transferin Bimolecular System of NH_3 and H_2O

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Chinese Journal of Structural Chemistry 2001年第5期20卷 339-343页

作者： FAN Jian-Fen XIA Qi-Ying B.van de Graaf XIAO He-Ming S.l.Njo Department of Chemistry Suzhou UniversitySuzhou 215006 China Faculty of Chemical Engineering and Material Science Delft University of TechnologyJulianalaan 136262 DelftNetherlands Department of Chemistry Nanjing University of Science and TechnologyNanjing 210094China

Mulliken, NPA, MK and CHelpG population analyses have been accomplished at the level of MP2/6-31G（d,p） for the title system. The variations of four kinds of charges on NH3 with intermolecular distance infer that electron transfers from NH3 to H2O. MK and CHelpG population analyses indicate more electron transfer than Mulliken and NPA ones. The atomic charges resulted from MK and CHelpG schemes infer that electron transfers from N in NH3 to H in H2O, which confirms that this bimolecular complex possesses linear structure as H3N…HOH.

关键词： bimolecular system of NH_3 and H_2O electron transfer MK and CHelpG charges ab initio calculation

Design and analysis of control system using neural network for regulated DC power supply

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Frontiers of Electrical and Electronic Engineering in China 2011年第4期6卷 567-574页

作者： Z I DAFAllA Jihad Alkhalaf BANI-YOUNIS l K WAH IT Department Ibri College of Applied SciencesIbri 516Oman Dean Office Ibri College of Applied SciencesIbri 516Oman Faculty of Engineering Multimedia UniversityCyberjaya 63100Malaysia

Conventional control systems used for regulated power supplies,including the proportional integral and derivation(PID)controller,have some serious *** PID controller has a delayed feedback associated with the control action and requires a lot of mathematical *** paper presents a novel controlling system based on the artificial neural network(ANN),which can be used to regulate the output voltage of the DC power *** MATlABTM,the designed control system was tested and analyzed with two types of back-propagation *** paper presents the results of the simulation that includes sum-squared error(SSE)and mean-squared error(MSE),and gives a detailed comparison of these values for the two *** verification of the new system,using RS232 interface and Microsoft Visual Basic 6.0,was implemented,showing very good consistency with the simulation *** proposed control system,compared to PID and other conventional controllers,requires less mathematical derivation in design and it is easier to implement.

关键词： regulated power supply neural network proportional integral and derivation(PID)controller multi-layer perceptron(MlP)network

Joint spatial modelling of disease risk using multiple sources:an application on HIV prevalence from antenatal sentinel and demographic and health surveys in Namibia

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Global Health Research and Policy 2017年第1期2卷 143-158页

作者： D.Ntirampeba I.Neema l.N.Kazembe Department of Mathematics and Statistics Namibia University of Science and TechnologyWindhoek 2064Namibia Namibia Statistics Agency(NSA) Windhoek 2064Namibia Department of Statistics and Population Studies University of NamibiaP/Bag 13301 PionersparkWindhoek 2064Namibia

Background:In disease mapping field,researchers often encounter data from multiple *** data are fraught with challenges such as lack of a representative sample,often incomplete and most of which may have measurement errors,and may be spatially and temporally *** paper presents a joint model in the effort to deal with the sampling bias and ***:A joint(bivariate)spatial model was applied to estimate HIV prevalence using two sources:2014 National HIV Sentinel survey(NHSS)among pregnant women aged 15-49 years attending antenatal care(ANC)and the 2013 Namibia Demographic and Health Surveys(NDHS).Results:Findings revealed that health districts and constituencies in the northern part of Namibia were found to be highly associated with HIV ***,the study showed that place of residence,gender,gravida,marital status,number of kids dead,wealth index,education,and condom use were significantly associated with HIV infection in ***:This study had shown determinants of HIV infection in Namibia and had revealed areas at high risk through HIV prevalence ***,a joint modelling approach was used in order to deal with spatially misaligned ***,it was shown that prediction of HIV prevalence using the NDHS data source can be enhanced by jointly modelling other HIV data such as NHSS *** findings would help Namibia to tailor national intervention strategies for specific regions and groups of population.

关键词： HIV prevalence Joint(bivariate)analysis Spatial analysis Namibia

MEASUREMENT OF AMPlITUDE AND DElAY OF STIMUlUS FREQUENCY OTOACOUSTIC EMISSIONS

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Journal of Otology 2013年第1期8卷 57-62页

作者： Tianying Ren Jiefu Zheng Wenxuan He Alfred l. Nuttall Oregon Hearing Research Center Department of Otolaryngology and Head & Neck SurgeryOregon Health and Science University3181 SW Sam Jackson Park RoadPortlandOR 97239 Department of Radiology Nuclear Medicine University of Iowa Hospitals and Clinics200 Hawkins DriveIowa CityIA 52242

Although stimulus frequency otoacoustic emissions (SFOAEs) have been used as a non-invasive measure of cochlear mechanics, clinical and experimental application of SFOAEs has been limited by difficulties in accurately deriving quantitative information from sound pressure measured in the ear canal. In this study, a novel signal processing method for multicomponent analysis (MCA) was used to measure the amplitude and delay of the SFOAE. This report shows the delay-frequency distribution of the SFOAE measured from the human ear. A low level acoustical suppressor near the probe tone significantly suppressed the SFOAE, strongly indicating that the SFOAE was generated at characteristic frequency locations. Information derived from this method may reveal more details of cochlear mechanics in the human ear.

关键词： MEASUREMENT OF AMPlITUDE AND DElAY OF STIMUlUS FREQUENCY OTOACOUSTIC EMISSIONS MCA SDC lDC Figure

Correct Interpretation of Creep Rates: A Case Study of Cu

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Journal of Materials Science & Technology 2015年第11期31卷 1065-1068页

作者： W.Blum J.Dvoák P.Král P.Eisenlohr V.Sklenika Institut für Werkstoffwissenschaften University of Erlangen-Nürnberg Institute of Physics of Materials Academy of Sciences of the Czech Republic Department of Chemical Engineering and Materials Science Michigan State University

Traditionally the deformation resistance in creep is characterized by the minimum creep rate εmin and its sensitivity to stress （stress exponent n） and temperature （activation energy Q）. Various values of constant n have been reported in the literature and interpreted in terms of specific mechanisms. The present case study of coarse-grained Cu at 573 K yields a stress exponent n = 9 for εmin. in tension and a relatively low activation energy. The evolution of the deformation resistance with strain at constant tensile creep load and comparison with creep in compression without fracture indicates that the tensile εmin. result from transition from uniform deformation to strain localization during fracture. This is confirmed by the results of creep in compression where fracture is suppressed. Both the tensile εmin, and the compressive creep rate at strains around 0.3 can be described using existing equations for quasi-stationary deformation containing the subgrain boundary misorientation θ as structure parameter. While in the latter case constant θ leads to monotonic increase of n with stress, the tensile nine-power-law results from variable θ, and has no simple meaning. The result of this case study means that uncritical interpretation of minimum tensile creep rates as stationary ones bears a high risk of systematic errors in the determination of creep parameters and identification of creep mechanisms.

关键词： Cu Creep Minimum creep rate Activation energy Stress exponent

Power-expected-posterior prior Bayes factor consistency for nested linear models with increasing dimensions

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Statistical Theory and Related Fields 2020年第2期4卷 162-171页

作者： D.Fouskakis J.K.Innocent l.Pericchi Department of Mathematics National Technical University of AthensAthensGreece Department of Mathematics University of Puerto RicoSan JuanUSA

The power-expected-posterior prior is used in this paper for comparing nested linear *** asymptotic behaviour of the method is investigated for different values of the power parameter of the *** is given on the consistency of the Bayes factor of comparing the full model M_(p) versus a generic submodel M_(l).In each case,we allow the true generating model to be either M_(p) or M_(l) and we keep the dimension of M_(l) fixed,while the dimension of M_(p) can be either fixed or(grow as)O(n),with n denoting the sample size.

关键词： Bayesian model selection Bayes factor consistency expected-posterior prior Gaussian linear models increasing dimension power-expected-posterior prior