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Childhood malaria in the Niger delta area of Nigeria:mothers/care givers'perception,definition and treatment practices

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Asian Pacific Journal of Tropical Medicine 2009年第3期2卷 52-58页

作者： Idogun E.Sylvester Airauhi l.u Department of Chemical Pathology University of Benin Teaching HospitalBenin City Department of Medical Microbiology Biology University of Benin Teaching HospitalBenin City

Objective:The objective of the study was to evaluate mothers/care givers perception of malaria,their treatment practices and the effects on the outcome of ***:Four hundred and sixty children were enrolled and their mothers/care givers *** children were screened for malaria parasitaemia and there after,blood specimens were obtained for biochemical and haematological evaluation from those children who met the criteria and tested positive to *** *** cell volume,electrolytes,urea, creatinine,plasma glucose,and serum bilirubin were ***:A total of 460 children were studied, 233(50.7%) males and 227(49.3%) *** malaria cases were 112(24.3%) and severe malaria 348(75.7%).Those who presented early 106(23.0%) and those who presented late 354(77.0%).Perception and definition of malaria as well as the treatment seeking behaviors vary significantly with the level of education of the mothers and care *** without formal education 68(51.9%) wrongly perceived that the etiology of malaria can only be diagnosed by native doctors compared to those with primary six education 61 (26.5%) and junior secondary education 10(10.1%).Only 43(9.3%) gave the correct dose of chloroquine syrup to their sick children,while 32(7.0%) gave at sub optimal ***:Wrong perception of malaria especially the complicated malaria and wrong treatment practices are major contributory factors to the high mortality and morbidity of malaria in *** is therefore a need for health education to correct the wrong ideas about the cause and treatment practices of malaria as part of malaria control programme.

关键词： Childhood malaria Mothers/Caregivers Perception and treatment practices Nigeria

Growth kinetics of interfacial reaction layer products between cubic boron nitride and Cu-Sn-Ti active filler metal

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Journal of Materials Science & Technology 2021年第33期92卷 69-74页

作者： yonggang Fan Cong Wang School of Metal.urgy Northeastern UniversityShenyang110819China State Key laboratory of Solid lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China

In the present investigation,the growth kinetics of interfacial reaction layer products between cubic boron nitride(CBN) and Cu-Sn-Ti filler metal has been thoroughly *** morphological and compositional features of respective compounds have been demonstrated for a wide brazing temperature ranging from 1153 K to 1223 *** is found that within 30 minutes brazing holding time,the reaction layer growth is largely determined by the population of Ti N via effective Ti diffusion with an activation energy of 223.51 k J/mol,leading to parabolic growth *** is further revealed that TiN grows both in axial and length dimensions,which eventually extends to the forefront and covers the reaction layer.

关键词： Cubic boron nitride Cu-Sn-Ti Interfacial reaction layer Activation energy

Force and impulse multi-sensor based on flexible gate dielectric field effect transistor

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International Journal of Minerals,Metal.urgy and Materials 2025年第1期32卷 214-220页

作者： Chao Tan Junling lü Chunchi Zhang Dong liang lei Yang Zegao Wang College of Materials Science and Engineering Sichuan UniversityChengdu 610065China The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China

Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other ***-dimensional material-based filed effect transistor(2D-FET)sensors are competitive with nano-level size,lower power consumption,and accurate ***,few of them has the capability of impulse detection which is a path function,expressing the cumulative effect of the force on the particle over a period of *** we fabricated the flexible polymethyl methacrylate(PMMA)gate dielectric MoS_(2)-FET for force and impulse sensor *** systematically investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signals(I_(ds))to the detected impulse(I).The applied force was detected and recorded by I_(ds)with a low power consumption of~30 *** sensitivity of the device can reach~8000%and the 4×1 sensor array is able to detect and locate the normal force applied on ***,there was almost no performance loss for the device as left in the air for two months.

关键词： flexible gate dielectric transistor force sensor impulse sensor force sensor array

Relative homological dimensions in recollements of triangulated categories

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Frontiers of Mathematics in China 2019年第1期14卷 25-43页

作者： yonggang Hu Hail.u YAO College of Applied Sciences Beijing University of Technology Beijing 100124 China

let E be a proper class of triangles in a triangulated category C, and let (A, B, C) be a recollement of triangulated categories. Based on Beligiannis's work, we prove that A and C have enough E-projective objects whenever B does. Moreover, in this paper, we give the bounds for the E-global dimension of B in a recollement (A, B, C) by controlling the behavior of the E-global dimensions of the triangulated categories A and C: In particular, we show that the finiteness of the E-global dimensions of triangulated categories is invariant with respect to the recollements of triangulated categories.

关键词： Triangula ted category proper class of triangles recollement Sglobal dimension derived category

Hsa-miR-214-3p inhibits breast cancer cell growth and improves the tumor immune microenvironment by downregulating B7H3

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Oncology research 2025年第1期33卷 103-121页

作者： Yan lu Kang Wang Yuanhong Peng Meng Chen lin Zhong luji Huang F u Cheng Xindan Sheng Xin Yang Manzhao Ouyang George A Calin Zhiwei He China-America Cancer Research Institute Guangdong Medical University Dongguan 523808 China. GCP Center Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China. Department of Gastrointestinal Surgery Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China. The Second School of Clinical Medicine Southern Medical University Guangzhou 510080 China. Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Houston TX 77030 USA. Department of Oncology Shunde Hospital Southern Medical University (The First People's Hospital of Shunde Foshan) Shunde 528300 China.

Background:Immune checkpoint inhibitors play an important role in the treatment of solid tumors, but the currently used immune checkpoint inhibitors targeting programmed cell death-1 (PD-1), programmed cell death ligand-1 (PD-l1), and cytotoxic T-lymphocyte antigen-4 (CTlA-4) show limited clinical efficacy in many breast cancers. B7H3 has been widely reported as an immunosuppressive molecule, but its immunological function in breast cancer patients remains unclear.Methods:We analyzed the expression of B7H3 in breast cancer samples using data from the Cancer Genome Atlas Program (TCGA) and the Gene Expression Omnibus (GEO) databases. MicroRNAs were selected using the TarBase, miRTarBase, and miRBase databases. The regulatory role of the microRNA hsa-miR-214-3p on B7H3 was investigated through dual-luciferase reporter assays, which identified the specific action sites of interaction. The expression levels of B7H3 and hsa-miR-214-3p in human breast cancer tissues and adjacent normal tissues were quantified using Western blotting and quantitative PCR (qPCR). experiments were performed to observe the effects of modulating the expression of B7H3 or hsa-miR-214-3p on breast cancer cell proliferation and apoptosis. Additionally, the regulatory impact of hsa-miR-214-3p on B7H3 was examined. Enzyme-linked immunosorbent assays (ElISA) and flow cytometry were employed to assess the effects of co-cul.ured breast cancer cells and normal human peripheral blood mononuclear cells (PBMCs) on immune cells and associated cytokines.Results:In breast cancer tissues, the expression level of B7H3 is inversely correlated with that of hsa-miR-214-3p, as well as with the regulatory effects on breast cancercell behavior. Hsa-miR-214-3p was found to inhibit breast cancer cell growth by downregulating B7H3. Importantly, our research identified, for the first time, two binding sites for hsa-miR-214-3p on the 3' uTR of B7H3, both of which exert similar effects independently. Co-cul.ure experime

关键词： B7H3 Breast cancer Hsa-miR-214-3p Immunotherapy

Chemiluminescence detection of permanganate index (COD_(Mn)) by a luminol-KMnO_4 based reaction

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Journal of Environmental Sciences 2008年第2期20卷 252-256页

作者： TIAN Jinjun Hu yonggang ZHANG Jie College of Environmental Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China Nanyang Institute of Technology Nanyang 473004 China

A novel chemiluminescence （Cl） system for determination of permanganate index （CODMn） combined with flow injection analysis has been proposed in this study. On the basis of the chemiluminescent reaction of luminol-KMnO4 system, light emission caused by luminol-KMnO4 system was detected by the photomultiplier tube, and its intensity caused by the appearance of KMnO4 after sample digestion was inversely proportional to CODMn. Effects for CODMn determining such as pH, concentrations and interference were investigated in detail. A detection limit of 0.3 mg/l CODMn with a linear range of 0.3-200 mg/l for its theoretical CODMn was obtained under the optimized experimental conditions. The relative standard deviation was 4.3% for 5.0 mg/l CODMn （n = 11）. This Cl flow system for determining CODMn was simple, rapid, and suitable for automatic analysis. The data obtained by the present method were fairly in good agreement with those obtained by the standard titrimetric method. It has been applied to determine real samples with satisfactory results.

关键词： flow-injection chemiluminescence permanganate index (CODMn) luminol-KMnO4

Garnet-type Solid-state Electrolyte li7la3Zr2O12:Crystal Structure,Element Doping and Interface Strategies for Solid-state lithium Batteries

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Chemical Research in Chinese universities 2020年第3期36卷 329-342页

作者： GuO Sijie SuN yonggang CAO Anmin CAS Key Laboratory of Molecular Nanostructure and NanotechnologyBeijing National Laboratory for Molecular SciencesInstitute of ChemistryChinese Academy of Sciences(QiS)Beijing 100190P.R.China School of Chemical Sciences University of Chinese Academy of SciencesBeijing 100049P.R.China

The eetimous devedqpmaut et soid-ae elestrolyte(SSEs)has slimuliteal immese progres in the development of lllia stle batrierdA8S8s Particularly,grmestyped S8Es in fomula of li7la3Zr2O12(llZO)are under intesive invesigtion如eaplit their advantage im high lithium ious condaxtiriy(>1 mSicm)wide cletrochemical window(>5V),and good chenical electrochemical stability for lithium,which are critical factors to ensure a stabl,and high performance *** review will focus on the challages related to llZOs-based electrolyte,and update the recent developments in structurl design of llZOs,which are disussed in three major sections;(i)crystal structure and the lithium-ion transport mechanismn of llZ0;(ii)single-site and multi-ite doping of li sites,la sites and Zr sites to enhance li ions conductivity(lIC)and sability of llZO;(iii)interface strategies between electrodes and llZ0 to decrease inertaee re-pcife reistence(ASR).

关键词： Solid-tate oetrolyte Gamot li ions condutirity Doping Surface coating

Guest editorial: Special Issue on Science of Wear

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Friction 2018年第3期6卷 243-244页

作者： yonggang MENG Valentin l.POPOV Jean-Fran?ois MOlINARI State Key laboratory of Tribology Tsinghua University Institute of Mechanics Technische Universit?t Berlin Civil Engineering Department Materials Science Department école Polytechnique Fédérale de Lausanne

Among the basic tribological phenomena of contact,adhesion, friction, lubrication and wear, wear remains the least scientifically understood. At the same time,wear remains one of the most important tribological phenom... 详细信息

关键词：摩擦学工艺优化可持续发展摩擦理论

A review on carbon/magnetic metal composites for microwave absorption

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Journal of Materials Science & Technology 2021年第27期86卷 91-109页

作者： Baolei Wang Qian Wu yonggang Fu Tong l.u Key laboratory of Aerospace Materials and Performance(Ministry of Education) School of Materials Science and EngineeringBeihang UniversityBeijing 100191China

At present,developing high-efficiency microwave absorption materials with properties including lightweight,thin thickness,strong absorbing intensity and broad bandwidth is an urgent demand to solve the electromagnetic pol.ution *** ideal microwave absorber should have excellent dielectric and magnetic loss capabilities,thereby inducing attenuation and absorption of incident electromagnetic ***,various carbon/magnetic metal composites have been developed and expected to become promising candidates for high-performance microwave *** this review,we introduce the mechanisms of microwave absorption and summarize the recent advances in carbon/magnetic metal *** methods and microwave absorption properties of carbon/magnetic metal composites with different components,morphologies and microstructures are discussed in ***,the challenges and future prospects of carbon/magnetic metal absorbing materials are also proposed,which will be useful to develop high-performance microwave absorption materials.

关键词： Carbon/magnetic metal composites Component Microstructure Microwave absorption properties Absorbing mechanism