检索结果-南通市图书馆

Geometrical Scale-Sensitive Fatigue Properties of Ti-6.5Al-3.5Mo-1.5Zr-0.3Si Alloys With α/β lamellar Microstructures

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2014年第12期30卷 1284-1288页

作者： B.Zhang Z.M.Song l.M.lei l.kang G.P.Zhang Key laboratory for Anisotropy and Texture of Materials Ministry of Education Northeastern University Shenyang National laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences AVIC Commercial Aircraft Engine Co. Ltd.

Fatigue properties of the Ti-6.5Al-3.5Mo-1.5Zr-0.3Si alloy sheets containing different numbers of α/β Widmansttten colonies in the thickness direction of the sheets were investigated by tensionetension fatigue testing. It is found that fatigue properties of the Ti alloy either in low- or high-stress amplitude regimes become more sensitive to the sheet thickness of the Ti alloy as the sheet thickness is comparable to the length scale of the Widmansttten colonies. The basic mechanism of such length scale-sensitive fatigue properties in the Ti alloy was elucidated.

关键词： Fatigue Ti alloy Microstructure Size effect

维普期刊数据库

Non-existence of Shimura curves of Mumford type generically in the non-hyperelliptic locus

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2025年

作者： Xin lü Shengli Tan kang Zuo School of Mathematical Sciences Key Laboratory of Mathematics and Engineering Applications(Ministry of Education) Shanghai Key Laboratory of Pure Mathematics and Mathematical PracticeEast China Normal University School of Mathematics and Statistics Wuhan University Institut für Mathematik Universit?t Mainz

We show that there does not exist any Shimura curve with a strictly maximal Higgs field generically in the Torelli locus of non-hyperelliptic curves of genus g≥4. In particular, Shimura curves of Mumford type are not...

关键词：

微波近场显微镜及其在超导薄膜和衬底材料特性无损检测上的应用

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

低温物理学报 1999年第4期21卷 39-43页

作者：冯一军刘雷刘庆国尤立星杨森祖吴培亨南京大学电子科学与工程系

高温超导薄膜的微波性能受制备工艺和衬底材料性能的影响，常常出现空间不均匀分布，因此，无损检测大面积超导薄膜及衬底材料的微波性能，研究影响局域微波性能的因素，是高温超导微波器件应用研究中的一个重要方面．我们设计和制造了... 详细信息

高温超导薄膜的微波性能受制备工艺和衬底材料性能的影响，常常出现空间不均匀分布，因此，无损检测大面积超导薄膜及衬底材料的微波性能，研究影响局域微波性能的因素，是高温超导微波器件应用研究中的一个重要方面．我们设计和制造了一套同轴谐振腔型微波近场扫描显微镜，利用该显微镜研究了金属薄膜样品微波表面电阻和介质材料的介电常数的空间分布，给出了其空间分辨率并分析了影响空间分辨率的因素．利用这套微波近场扫描显微镜，对大面积ＬａＡｌＯ３单晶衬底材料介电常数的空间分布进行了测量，并分析了其测量精度．最后，利用这套微波近场扫描显微镜，研究了ＹＢａＣｕＯ薄膜平面微波器件的微波表面电阻的分布情况，对影响其局域微波性能的因素做了初步分析

关键词：显微镜高温超导制备工艺实验设备衬底材料谐振腔表面电阻表面比电阻介质材料针尖半径微波性能介电常数电容率介电性质薄膜样品无损检测无损探伤材料试验微波电磁波近场电磁场

用扩展长度的半球透镜改善Josephson结与毫米波的耦合

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

低温物理学报 1999年第2期21卷 3-5页

作者：葛阳中吉争鸣张新宇周军冯一军康琳杨森祖吴培亨南京大学电子科学与工程系

为了改善Ｊｏｓｅｐｈｓｏｎ结和ｍｍ波辐射之间的耦合，我们设计了与温度超导薄膜台阶衬底相同介质的ＬＡＯ扩展半球透镜系统．运用积分方程法求解了不同扩展长度之下，ＬＡＯ透镜系统的远场方向图形，据此确定了最佳扩展长度Ｄｏｐｔ... 详细信息

为了改善Ｊｏｓｅｐｈｓｏｎ结和ｍｍ波辐射之间的耦合，我们设计了与温度超导薄膜台阶衬底相同介质的ＬＡＯ扩展半球透镜系统．运用积分方程法求解了不同扩展长度之下，ＬＡＯ透镜系统的远场方向图形，据此确定了最佳扩展长度Ｄｏｐｔ．进而，用ＹＢＣＯ薄膜台阶结作为检测元，在有和没有透镜系统时作了实验对比测量，结果表明增加了该透镜系统后，结与１０３ＧＨｚ的信号耦合提高了１４ｄｂ．

关键词：透镜系统准光学微波光学 Josephson 球透镜毫米波极高频衬底基片积分方程法半球长度

Film-Cooling Performance with Various Hole length to Diameter Ratios for Cylindrical and laidback Fan-Shaped Holes with an Inlet Groove

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2025年第02期 607-625页

作者： PARK Jisu KIM Jun-Hee kang Changwoo Department of Mechanical Engineering Jeonbuk National University Research Institute of Industrial Science & Technology 187-12 Geumho-ro laboratory for Renewable Energy and Sector Coupling Jeonbuk National University

The influence of the hole length-to-diameter ratio on film-cooling performance is numerically investigated for a cylindrical hole and laidback fan-shaped hole with an inlet *** analysis of film-cooling is conducted by solving three-dimensional Reynolds-averaged Navier-Stokes equations(RANS)with a Realizable k-ε turbulence *** and triangular grooves are applied to the inlet of cylindrical and laidback fan-shaped *** ratio of the hole length(l) to the diameter(D),i.e.,l/D,is varied between 6-12 at blowing ratios(M) of 0.5 to 1.5 for the cylindrical hole and 0.5 to 3.0 for the laidback fan-shaped *** cylindrical holes with an inlet groove,the film-cooling effectiveness decreases as the l/D increases,regardless of the blowing ***,in the case of laidback fan-shaped holes,the cooling performance with the length-to-diameter ratios shows different tendencies for each blowing *** low blowing ratios(M=1.0),relatively high effects were observed with more than 5% increases in the effectiveness at l/D=10 and 12 compared to that of l/D=***,the performance is maximized at l/D=8 under high-blowing-ratio conditions(M=3.0).The cooling efficiency is enhanced up to 148% for square grooves and 124% for triangle grooves compared to those of l/D=6.

关键词：

Self-assembly of two pairs of homochiral M2l4 coordination capsules with varied confined space using Tr?ger's base ligands

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical letters 2025年第2期36卷 360-365页

作者： Yi Zhou Wei Zhang Rong Fu Jiaxin Dong Yuxuan liu Zihang Song Han Han kang Cai College of Chemistry Nankai University Department of Chemistry Northwestern University Department of Chemistry The University of Hong Kong

Chiral coordination molecular cages/capsules with discrete nanoconfined chiral cavities demonstrate significant potential applications across various fields. In this study, we utilized Tr?ger's base as the building block to design and synthesize two pairs of enantiopure ligands. These ligands were then self-assembled with Pd(II) ions through chiral self-sorting coordination, resulting in the formation of two pairs of homochiral M2l4-type coordination molecular capsules. Notably, due to differences in the substitution positions on the Tr?ger's base, these two pairs of enantiomeric coordination molecular capsules exhibited distinct levels of cavity closures, cavity sizes, and host-guest recognition properties. This research offers valuable insights into the construction of novel chiral molecular capsules and the regulation of confined cavities.

关键词： Chirality Host-guest recognition Metal-organic capsule Self-sorting Tröger's base

Adenosine triphosphate-binding pocket inhibitor for mixed lineage kinase domain-like protein attenuated alcoholic liver disease via necroptosis-independent pathway

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第6期31卷 44-61页

作者： Han-Ning Xuan Yuan Hyun Sung Kim Gye Ryeol Park Jae Eun Ryu Ji Eun Kim In Young kang Hye Young Kim Seung Min lee Ju Hee Oh Eileen l Yoon Dae Won Jun Department of Internal Medicine Hanyang University School of MedicineSeoul 04763South Korea Department of Pathology Hanyang University School of MedicineSeoul 04763South Korea Department of Translational Medicine Graduate School of Biomedical Science and EngineeringHanyang UniversitySeoul 04763South Korea Department of Obstetrics and Gynecology Institute of Women’s Medical Life ScienceYonsei Cancer CenterSeverance HospitalYonsei University College of MedicineSeoul 04763South Korea Department of Internal Medicine Sanggye Paik HospitalInje University College of MedicineSeoul 01757South Korea

BACKGROUND Mixed lineage kinase domain-like protein(MlKl)serves as a critical mediator in necroptosis,a form of regulated cell death linked to various liver *** study aims to specifically investigate the role of MlKl’s adenosine triphosphate(ATP)-binding pocket in facilitating necroptosis-independent pathways that may contribute to liver disease *** focusing on this mechanism,we seek to identify potential therapeutic targets that can modulate MlKl activity,offering new strategies for the prevention and treatment of liver-related *** To investigate the possibility of using the ATP-binding pocket-associated,necro-ptosis-independent MlKl pathway as a target for liver *** Cell death following necroptosis stimuli was evaluated using cell proliferation assays,flow cytometry,and electron microscopy in various *** human liver organoid system was used to evaluate whether the MlKl ATP pocket-binding inhibitor could attenuate ***,alcoholic and non-alcoholic fatty liver diseases animal models were used to determine whether MlKl ATP pocket inhibitors could attenuate liver *** While an MlKl ATP pocket-binding inhibitor did not prevent necroptosis-induced cell death in RAW 264.7 cells,it did reduce the necroptosis-led expression of CXCl2,ICAM,and ***,MlKl ATP pocket inhibitor diminishes the expression of CXCl2,ICAM,and VCAM by inhibiting the IκB kinase and nuclear factor kappa-B pathways without inducing necroptosis-induced cell death in two-dimensional cell culture as well as the human-derived liver organoid *** MlKl ATP-binding inhibitor was ineffective in non-alcoholic fatty liver disease animal models,MlKl ATP-binding inhibitor attenuated hepatic inflammation in the alcoholic liver disease *** MlKl ATP pocket-binding inhibitor exerted anti-inflammatory effects through the necroptosis-independent MlKl pathway in an animal model of alcoholic liver disease.

关键词： RAW 264.7 cell Cell death Necroptosis Mixed lineage kinase domain-like protein Non-alcoholic fatty liver disease Mixed lineage kinase domain-like protein adenosine triphosphate binding inhibitor Alcoholic liver disease

A new Synbiotic supplementation ameliorates ulcerative colitis via modulating microbial homeostasis， protecting intestinal barrier integrity， and maintaining immunity homeostasis in mice

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2025年

作者： Yongbo kang liping li Jing Guo Yue Cai Ying Yang Department of microbiology and immunology， School of Basic Medical Sciences， Shanxi Medical University Department of Endocrinology Affiliated Hospital of Yunnan University

Ulcerative colitis [UC] is established by a chronic， diffuse inflammation of colonic mucosa with poorly defined etiology， and without sufficient treatment or cure available for remission. In this context， there is a growing recognition and consensus that synbiotic supplement may be promising and impactful strategies towards ameliorating UC and related inflammatory disorders， garnering significant attention from researchers as an alternative therapy. Herein， we innovatively prepared a novel synbiotic combination including lactobacillus acidophilus， Bifidobacterium infants and prebiotics konjac glucomannan oligosaccharides [KGMO] to explore the potential therapeutic effects in dextran sodium sulfate [DSS] induced UC mouse model. The results demonstrated that the synbiotic effectively improved colitis symptoms in mice by mitigating weight loss， disease activity index [DAI]， colonic pathological damage， and colonic oxidative stress. it also observed that the synbiotic preserve intestinal barrier function integrity， reduces metabolic endotoxemia as well as inhibits the TlR4/NF-κB， NlRP3/Caspase-1， and Nrf2/Keap1 signaling pathway. Furthermore， the synbiotic modulated microbial homeostasis directly by enhancing beneficial microbes and reducing potentially harmful bacteria. In addition， microbiome phenotype prediction and bacterial functional potential prediction analysis demonstrated that the synbiotic supplementation regulated gut microbiota function involving inflammatory injury， metabolism， immune response， and pathopoiesia. Especially， the synbiotic not only restored the balance of Th1/Th2 cells as well as Th17/Treg cells along with specific inflammatory factors expression， but also maintained bile acid homeostasis by regulating FXR/FGF15 signaling pathway. Especially important is that the synbiotic was as effective as mesalazine against UC. According to above data， it is seen that this novel synbiotic could be a good candidate drug for ameliorating UC through its ant

关键词：

Prediction of intrusive gas pores caused by resin burning in sand core for iron castings

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2025年第1期22卷 23-32页

作者： Ji-wu Wang Xiao-long Wang Yu-cheng Sun Yu-hang Huang Xiu-ming Chen Xiong-zhi Wu Na li Jin-wu kang Tao Jing Tian-you Huang Hai-liang Yu School of Mechanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China Weichai Power Co. Ltd.Weifang 261061ShandongChina School of Mechanical Engineering Central South UniversityChangsha 41000China School of Materials Science and Engineering Key Laboratory for Advanced Materials Processing TechnologyTsinghua UniversityBeijing 100084China

In the production of castings,intrusive gas pore represents a kind of common defects which can lead to leakage in high gas-tightness requirement castings,such as cylinder blocks and cylinder heads for *** occurs due to the intrusion of gases generated during the resin burning of the sand core into castings during the casting ***,a gas generation and flow constitution model was established,in which the gas generation rate is a function of temperature and time,and the flow of gas is controlled by the gas release,conservation,and Darcy's *** heat transfer and gas flow during casting process was numerically *** dangerous point of cores is firstly identified by a virtual heat transfer method based on the similarity between heat transfer and gas flow in the sand *** gas pores in castings are predicted by the gas pressure,the viscosity and state of the melt for these dangerous *** distinct sand core structures were designed and used for the production of iron castings,and the simulated gas pore results were validated by the obtained castings.

关键词： gas pore numerical simulation iron casting sand core resin

维普期刊数据库