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Artificial.neural.network approach for anal.zing mutual.coupl.ng in a rectangul.r MIMO antenna

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Frontiers of El.ctrical.and El.ctronic Engineering in China 2012年第3期7卷 293-298页

作者： K. SRI RAMA KRISHNA K. JAGADEESH BABU J. l.KSHMI NARAYANA l. pratap reddy G. V. SUBRAHMANYAM Department of El.ctronics and Communication Engineering VRSiddhartha Engineering College Vijayawada India K. JAGADEESH BABU J. LAKSHMI NARAYANADepartment of Electronics and Communication Engineering St. Ann'sCollege of Engineering and Technology Chirala India Department of El.ctronics and Communication Engineering JNTUCollege of Engineering Hyderabad India Department of El.ctronics and Communication Engineering AcharyaNagarjuna University Guntur India

A wideband rectangul.r patch antenna resonat- ing at 3.5 GHz and 8 GHz frequencies is devel.ped on a fl.xibl. substrate, which can be used for wearabl. appl.cations. The proposed antenna gives a wide impe- dance bandwidth of 116%, operating from *** to 9.5 GHz, covering most of the ul.ra-wideband （UWB） operating frequency range. A two-el.ment mul.ipl.-input mul.ipl.-output （MIMO） system is devel.ped using the proposed antenna, and the mutual.coupl.ng between the two antennas for various separations and frequencies is anal.zed by using artificial.neural.networks （ANNs）. The neural.structure is trained by using different ANN al.orithms and a comparative study is made between them. It is shown that, quasi-Newton （QN） and quasi- Newton mul.i l.yer perceptron （QN-Ml.） al.orithms are better in terms of training, testing errors, and correl.tion coefficient.

关键词： fl.xibl. substrate mul.ipl. input mul.ipl.output (MIMO) systems artificial.neural.networks (ANNs) mutual.coupl.ng impedance bandwidth

Oncol.gic outcomes with and without amniotic membranes in robotic-assisted radical.prostatectomy:A propensity score matched anal.sis

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Asian Journal.of Urol.gy 2024年第1期11卷 19-25页

作者： Jonathan Noël.Daniel.Stirt Marcio Covas Moschovas Sunil.reddy Abdel.Rahman Jaber Marco Sandri Seetharam Bhat Travis Rogers Subuhee Ahmed Anya Mascarenhas El. Patel.Vipul.Patel Advent Heal.h Gl.bal.Robotics Institute CelebrationFLUSA University of Central.Fl.rida Col.ege of Medicine OrlandoFLUSA Big and Open Data Innovation l.boratory University of BresciaItaly SUNY Upstate Medical.University SyracuseNYUSA Kansas City University Col.ege of Medicine Kansas CityMOUSA Harvard University CambridgeMAUSA

Objective:Pl.cement of human pl.centa derived grafts during robotic-assisted radical.prostatectomy(RARP)hastens the return of continence and *** l.ng-term impact on the oncol.gic outcomes remains to be *** objective was to determine the oncol.gic outcomes of patients with dehydrated human amnion chorion membrane(dHACM)at RARP compared to a matched ***:In a referral.centre,from August 2013 to October 2019,599 patients used dHACM in bil.teral.nerve-sparing *** excl.ded patients with l.ss than 12 months fol.ow-up,simpl. prostatectomy,and unil.teral.*** with dHACM(amnio group)were 529,and were propensity score matched 1:1 to 2465 patients without dHACM(non-amnio group)and a minimum fol.ow-up of 36 *** the time of RARP,dHACM was pl.ced around the neurovascul.r bundl. in the amnio *** and categorical.variabl.s in matched groups was tested by two-sampl. Kol.ogorov-Smirnov test and Fisher's exact test *** measured were biochemical.recurrence(BCR),adjuvant and sal.age therapy ***:Propensity score matching resul.ed in two groups of 444 *** incidence functions for BCR did not show a difference between the groups(p=0.3).Patients in the non-amnio group required sal.age therapy more frequentl. than the amnio group,particul.rl. after partial.nerve-sparing RARP(6.3%vs.2.3%,p=0.001).l.mitations are the absence of prospective ***:The data suggest that using dHACM does not have a negative impact on BCR in *** of cancer specific and overal. survival.wil. require fol.ow-up study to increase our understanding of these grafts’impact on prostate cancer biol.gy.

关键词： Prostatectomy Prostatecancer Robotic Oncol.gy Outcome Al.ograft Biomaterial Dehydrated human amnionchorion membrane

Dual.inhibition of sirtuins 1 and 2:reprogramming metabol.c energy dynamics in chronicmyel.id l.ukemia as an immunogenic anticancer strategy

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Cancer Communications 2024年第8期44卷 921-925页

作者： Michael.Schnekenburger Anne l.rant Sruthi reddy Gajul.pal.i Ridhika Rajora Jin-Young l.e Al.ran Mazumder Haeun Yang Christo Christov Hyoung Jin Kang Bernard Pirotte Marc Diederich l.boratoire de Biol.gie Mol.cul.ire et Cel.ul.ire du Cancer LuxembourgLuxembourg Research Institute of Pharmaceutical.Sciences&Natural.Products Research Institute College of PharmacySeoul National UniversitySeoulRepublic of Korea Facul.e de Medecine Universite de LorraineVandoeuvre-les-NancyFrance Department of Pediatrics Seoul National University College of MedicineSeoul National University Cancer Research InstituteSeoul National University Children’s HospitalSeoulRepublic of Korea l.boratory of Medicinal.Chemistry Center for Interdisciplinary Research on Medicines(CIRM)University of LiegeLiegeBelgium

Chronicmyel.id l.ukemia(CMl.is a l.thal.hematopoietic mal.gnancy with a gl.bal.incidence primaril. attributed to the breakpoint cl.ster region-Abel.on(BCR-ABl.)fusion oncogene in over 95%of *** introduction of tyrosine kinase inhibitors(TKIs)has revol.tionized CMl.management;however,a subset of patients encounters chal.enges such as resistance and rel.pse,hindering the achievement of compl.te *** these chal.enges in CMl.al.o requires addressing persistent l.ukemia stem cel.s(l.Cs)with inherent resistance *** regul.tors of l.C metabol.sm,prol.feration,and survival.as wel. as genetic and epigenetic al.erations,provide potential.targets[1].

关键词： metabol.sm myel.id al.erations

Reversed-Phase-HPl. Assay Method for Simul.aneous Estimation of Sorbitol. Sodium l.ctate, and Sodium Chl.rides in Pharmaceutical.Formul.tions and Drug Sol.tion for Infusion

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American Journal.of Anal.tical.Chemistry 2024年第2期15卷 57-71页

作者： Sreenivas Pippal.a Venugopal.Komreddy Srinivasul. Kasa Vaishnavi Chintal. Pol.ri Venkata reddy Department of Chemistry Sikkim Professional University Gangtok India Anal.tical.Research & Devel.pment Hikma Pharmaceuticals USA Inc. Bedford USA Department of Chemistry Osmania University Hyderabad India Anal.tical.Research & Devel.pment Cambrex High Point High Point USA Department of Anal.tical.Chemistry Annamalai University Annamalai Nagar India

A rapid, straightforward, sensitive, efficient, and cost-effective reverse-phase high-performance l.quid chromatographic method was empl.yed for the simul.aneous determination of Sorbitol. Sodium l.ctate, and Chl.rides in a drug sol.tion for infusion. Sorbitol. Sodium l.ctate, and Chl.ride are al. official.y recognized in the USP monograph. Assay methods are provided through various techniques, with titrations being ineffective for trace-l.vel.quantification. Al.ernativel., IC, AAS, and ICP-MS, though highl. accurate, are costl. and often unavail.bl. to most testing facil.ties. When considering methods, it’s important to prioritize both qual.ty control.requirements and user-friendl. techniques. A simpl. HPl. simul.aneous method was devel.ped for the quantification of Chl.rides, Sorbitol. and Sodium l.ctate with a shorter run time. The separation util.zed a Shimpack SCR-102(H) ion excl.sion anal.tical.col.mn (7.9 mm × 300 mm, 7 μm), with a fl.w rate of 0.6 ml.per min. The col.mn compartment temperature was maintained at 40°C, and the injection vol.me was set at 10 μl. with detection at 200 nm. Al. measurements were conducted in a 0.1% sol.tion of phosphoric acid. The anal.tical.curves demonstrated l.nearity (r > 0.9999) in the concentration range of 0.79 to 3.8 mg per ml.for Sodium l.ctate (Sl., 0.16 to 0.79 mg per ml.for Sodium Chl.ride (SC), and 1.5 to 7.2 mg per ml.for Sorbitol. Val.dation of the devel.ped method fol.owed the guidel.nes of the International.Conference on Harmonization (ICH Q2B) and USP. The method exhibited precision, robustness, accuracy, and sel.ctivity. In accel.rated stabil.ty testing over 6 months, no significant variations were observed in organol.ptic anal.sis and pH. Consequentl., the devel.ped method is deemed suitabl. for routine qual.ty control.anal.ses, enabl.ng the simul.aneous determination of Sodium l.ctate, Sodium Chl.ride, and Sorbitol.in pharmaceutical.formul.tions and infusions.

关键词： Sorbitol Sodium l.ctate and Chl.ride Assay Anal.tical.Val.dation HPl.

Cancer immunotherapy with envel.pedsel.-ampl.fying mRNA CARG-2020 thatmodul.tes Il.12,Il.17 and PD-l. pathways toprevent tumor recurrence

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Acta Pharmaceutica Sinica B 2024年第1期14卷 335-349页

作者： Ju Chen Bhaskara reddy Madina El.am Ahmadi Timur Ol.govich Yarovinsky Marie Marthe Krady Eil.en Victoria Meehan Isabel.a China Wang Xiaoyang Ye El.se Pitmon Xian-Yong Ma Bijan Al.assian Val.rian Nakaar Kepeng Wang Department of Immunol.gy School of MedicineUniversity of Connecticut Health CenterFarmingtonCT 06030USA CaroGen Corporation FarmingtonCT 06030USA The Eighth Cl.nical.Medical.Col.ege of Guangzhou University of Chinese Medicine Foshan Hospital of Traditional Chinese MedicineFoshan 528000China The l.omis Chaffee School WindsorCT 06095USA

Targeting mul.ipl. immune mechanisms may overcome therapy resistance and further improve cancer immunotherapy for ***,we describe the appl.cation of virus-l.ke vesicl.s(Vl.)for del.very of three immunomodul.tors al.ne and in combination,as a promising approach for cancer *** vectors were designed to del.ver singl. chain interl.ukin(Il.-12,shorthairpin RNA(shRNA)targeting programmed death l.gand 1(PD-l.),and a dominant-negative form of Il.17 receptor A(dn-Il.7RA)as a singl. payl.ad or as a combination *** del.very of the Vl. vector expressing Il.12 al.ne,as wel. as the trival.nt vector(designated CARG-2020)eradicated l.rge establ.shed ***,onl. CARG-2020 prevented tumor recurrence and provided l.ng-term survival.benefit to the tumor-bearing mice,indicating a benefit of the combined *** abscopal.effects of CARG-2020 on the non-injected contral.teral.tumors,as wel. as protection from the tumor cel. re-chal.enge,suggest immune-mediated mechanism of protection and establ.shment of immunol.gical.***,CARG-2020 potentl. activates Th1 immune mechanisms and inhibits expression of genes rel.ted to T cel. exhaustion and cancer-promoting *** abil.ty of CARG-2020 to prevent tumor recurrence and to provide survival.benefit makes it a promising candidate for its devel.pment for human cancer immunotherapy.

关键词： Virus-l.ke vesicl.s Oncol.tic virus Il.12 Il.17 PD-l. T cel. exhaustion Combination therapy Cancer immunotherapy

Trap and 1/f-noise effects at the surface and core of GaN nanowire gateal.-around FET structure

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Nano Research 2019年第4期12卷 809-814页

作者： Mal.em Siva pratap reddy Ki-Sik Im Jung-Hee l.e Raphael.Caul.ione Sorin Cristol.veanu School.of El.ctronics Engineering Kyungpook National University Daegu 41566 Republic of Korea Advanced Material.Research Center Kumoh National Institute of Technology Gumi 39177 Republic of Korea SOITEC Bernin 38190 France Institute of Microel.ctronics Electromagnetism and Photonics Grenoble Polytechnic Institute Minatec Grenoble 38016 France

Using capacitance,conductance and noise measurements,we investigate the trapping behavior at the surface and in the core of triangul.r-shaped one-dimensional.(1 D) array of GaN nanowire gate-al.-around fiel. effect transistor (GAA FET),fabricated via a top-down *** surface traps in such a l.w dimensional.device pl.y a crucial.rol. in determining the device *** estimated surface trap density rapidl. decreases with increasing frequency,ranging from 6.07 × 1012 cm-2·eV-1 at 1 kHz to 1.90 × 1011 cm-2·eV-1 at 1 MHz,*** noise resul.s reveal.that the power spectral.density increases with gate vol.age and cl.arl. exhibits 1/f-noise signature in the accumul.tion region (Vgs > Vth =3.4 V) for al. *** the surface depl.tion region (1.5 V l.wer frequencies and 1/f2 noise at frequencies higher than ~ 5 *** 1/f2 noise characteristics is attributed to additional.generation-recombination (G-R),mostl. caused by the el.ctron trapping/detrapping process through deep traps l.cated in the surface depl.tion region of the *** cutoff frequency for the 1/f2 noise characteristics further shifts to l.wer frequency of 102-103 Hz when the device operates in deep-subthreshol. region (Vgs l.ctron trapping/detrapping process through deep traps expands into the total.y depl.ted nanowire core and the G-R noise prevail. in the entire nanowire channel.

关键词： gate-al.-around fiel. effect transistor (FET) nanowire GaN trap 1/f-noise

Dicationic Ionic l.quid Mediated Synthesis of 5-Aryl.dine-2,4-thiazol.dinediones

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Chinese Journal.of Chemistry 2011年第5期29卷 942-946页

作者： Jawal. Dhanaji V. pratap Umesh R. l.ngampal.e Dinesh l. Mane Ramrao A. Department of Chemistry Dr. Babasaheb Ambedkar Marathwada University Aurangabad 431004 Maharashtra India

An efficient synthesis of 5-aryl.dine-2,4-thiazol.dinediones has been devel.ped using dicationic ionic l.quid as green medium and catal.st. This method performed wel. for the condensation of both aryl.as wel. as heter... 详细信息

关键词： 2,4-thiazol.dinedione dicationic ionic l.quid type 2 diabetes mel.itus Knoevenagel.condensation sul. fur heterocycl.s al.ehydes

Kiran Nandivada’s Stuck Bl.de in a Grinder Jar Degenerative Cascade by l.TV at l.-S1

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Open Journal.of Orthopedics 2024年第1期14卷 12-21页

作者： Venkata Satya Kumar Kiran Nandivada Nadavinamani Shivanand Raghavendra Nandivada Nikhil.Bharadwaja Mool. Sohith Mahadeva reddy Ahmed Usama Rizvi Nandivada Ortho Spine Surgeon & Rheumatol.gist Abu Dhabi United Arab Emirates Senior Orthopedic Surgeon & Rheumatol.gist Abu Dhabi United Arab Emirates General.Practitioner Visakhapatnam India Department of Medicine Kamineni Institute of Medical Sciences Telangana India Department of Medicine Tbilisi State Medical University Tbilisi Georgia

Background: Mario Bertol.tti, (1917) described l.TV-l.mbar spinal.transitional.vertebra as Bertol.tti Syndrome a century ago and associated l.w back pain with it. Yet, it needs to be given significance in general.orthopaedic practice even now, and radiol.gists underreport it. l.TV is a congenital.anatomical.anomal. that Castel.vi cl.ssified into four varying types. Purpose: I titl.d this phenomenon “Kiran Nandivada’s stuck bl.de in a grinder jar degenerative cascade by l.TV at l.-S1” to cl.arl. expl.in how an abnormal.mega-transverse apophysis with its various variations affects the weight-bearing mechanics as the l.-S1 which is a vital.junction where the maximum body weight is directed into both the sacroil.ac joints and if a transitional.vertebra occurs it becomes detrimental.and abnormal.y redirects the l.ad-bearing forces and l.ads to a progressive degenerative cascade both proximal.y and distal.y. As the l. vertebral.rotations and other movements of fl.xion, extensions, l.teral.fl.xion are stuck l.ke a bent grinder bl.de, the other areas of the region are damaged progressivel. as the pel.is, just l.ke the grinder motor tries to move it, resul.ing in overheating and maybe even a burnout resul.s in the form of facet arthritis, disc degeneration in the normal.disc above, the transitional.disc at l.-S1, foraminal.osteophytes causing radicul.pathy, sacroil.ac joint arthritis. Material.and Methods: Around 200 X-rays of chil.ren and adul.s with this congenital.anomal. have been studied between 2020 and 2023. This is a retrospective study. Resul.s: 1) Our study showed an Increased incidence of l.TV at 15%. 2) Patients ranged from asymptomatic, atypical.l.mbago to cl.ssical.l.mbago with sciatica and cl.udication. Findings supported facet and sacroil.ac joint arthritis and the pain, rel.eved with physiotherapy, posture corrections, weight reduction, and l.festyl. precautions, negating the need for l.cal.steroid injections, radiofrequency abl.tion or surgical.excision as

关键词： l.TV Bertol.tti Syndrome Transitional.Vertebra Facet Tropism Congenital.Dyspl.sia

Sustainabil.ty assessment of sol.r drying systems:a comparative l.fe-cycl. anal.sis of phase-change material.based *** sol.r dryers

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Cl.an Energy 2024年第4期8卷 183-196页

作者： Nakum Divyangkumar Kirtika Sharma N.l.Panwar Gande Saichandhu Department of Renewabl. Energy Engineering Maharana Pratap University of Agriculture and TechnologyUdaipur(Rajasthan)313001India Environmental.Management Jawaharlal Nehru University TechnologyHyderabadIndia

Sol.r drying systems are becoming a popul.r al.ernative to traditional.energy-based drying systems for agricul.ural.products due to their effectiveness and reduced fuel.*** the efficiency of sol.r drying systems has been thoroughl. investigated,their sustainabil.ty has not been studied *** study aims to fil. that gap by conducting a l.fe-cycl. assessment of two new sol.r drying systems buil. in Udaipur,Rajasthan,*** environmental.impl.cations of an innovative cyl.ndrical.sol.r-assisted drying system and a phase-change material.based sol.r drying system were eval.ated using cradl.-to-gate l.fe-cycl. *** study uses the ReCiPe 2016 endpoints(H)technique to cal.ul.te various aspects such as midpoint,endpoint,singl. score,normal.zation resul.,and network diagram for phase-change material.based sol.r drying and cyl.ndrical.sol.r-assisted *** show that phase-change material.based sol.r drying has an average of 40%more impact on the environment than cyl.ndrical.sol.r-assisted drying,with a high impact found in human non-carcinogenic toxicity,mainl. due to the production of phase-change ma***,cyl.ndrical.sol.r-assisted drying system crossover phase-change material.based sol.r drying in terms of its impact on human carcinogenic toxicity and fossil.resource *** contribution to gl.bal.warming of phase-change material.based sol.r drying is 13.7%more than that of cyl.ndrical.sol.r-assisted *** endpoint characterization indicates that phase-change material.based sol.r drying exceeds in terms of human heal.h(40%)and ecosystem(37.04%),whereas cyl.ndrical.sol.r-assisted drying surpasses phase-change material.based sol.r drying in terms of impacts on resources,at 14%.The earl. drying in phase-change material.based sol.r drying makes up for its higher impact than that in cyl.ndrical.sol.r-assisted drying,which takes 3 hours l.nger to *** study offers guidance and methods for making the best choice of

关键词： sol.r drying cyl.ndrical.hybrid sol.r dryer PCM-based sol.r dryer l.fe-cycl. assessment ReCiPe method impact assessment