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Cal.bration of the deM sl.ding friction and rol.ing friction parameters of a cohesionl.ss bul. material

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particuol.gy 2024年第9期92卷 126-139页

作者： j.natan marín p.rez Tugrul.Coml.kci Yevgen Gorash Donal. MacKenzie University of Strathcl.de 75 Montrose StreetG11XJGlasgowUnited Kingdom

The discrete el.ment method(deM)has become a val.abl. tool.for understanding the mechanical.behaviour of granul.r assembl.es,however,the accuracy of the deM simul.tions depends on several.interaction parameters such as the sl.ding friction and rol.ing friction ***,these parameters are estimated using bul. cal.bration approach(BCA)where the draw down test has been suggested as an effective way to approach these *** test provides up to four bul. criteria,the angl. of repose,shear angl.,mass fl.w rate and the mass l.ss which are used to narrow down the possibl. ***,there is stil. more research needed around it to ful.y understand how this methodol.gy *** experimental.and numerical.study was carried out using the draw down test to assess the infl.ence of different mass fl.w rates and particl. shapes on deM parameters for a cohesionl.ss bul. *** is concl.ded that use of mul.i-sphere particl.s and three aperture sizes in the draw down test to cal.brate the sl.ding and rol.ing friction parameters of a cohesionl.ss bul. material.can converge to a smal. feasibl. region in which a singl. combination of the friction coefficients can be *** cal.brated sl.ding and rol.ing friction coefficients were val.dated using mul.i-sphere particl.s,where the maximum deviation was 5.9%from the experimental.val.es.

关键词： Discrete el.ment method Cal.bration Draw down Sl.ding friction Rol.ing friction particl. shape

Emerging rol. of A-kinase anchoring protein 5 signal.ng in reward circuit function

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Neural.Regeneration Research 2025年第10期20卷 2913-2914页

作者： Wil.iam j.Fl.rl.ge mark l.del.’Acqua Brian M.Cox Fereshteh S.Nugent Uniformed Services University of the Heal.h Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA department of pharmacol.gy University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a maj.r contributor to neural.circuit and network disruption underl.ing emotional.and mood dysregul.tion in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct mol.cul.r signal.ng pathways converge on the synapse to regul.te synaptogenesis,synaptic function,and synaptic pl.sticity in brain regions and circuits through compl.x interactions organized by numerous mul.ival.nt protein scaffol.s,incl.ding the famil. of proteins known as A-kinase anchoring proteins(AKAps).

关键词： function supporting

Effects of torpedo bl.sting on rockburst prevention during deep coal.seam mining in the Upper Sil.sian Coal.Basin

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j.urnal.of Rock Mechanics and Geotechnical.Engineering 2017年第4期9卷 694-701页

作者： l. Woj.ecki p. Konicek j. Schreiber pol.sh Mining Group Powstanców 30 Katowice 40-039 Poland department of Geomechanics and Mining Research Institute of Geonics Czech Academy of Sciences Studentska 1768 Ostrava-Poruba 708 00 Czech Republic

In the Upper Sil.sian Coal.Basin(USCB),coal.seams are expl.ited under progressivel. more difficul. geol.gical.and mining conditions(greater depth,higher horizontal.stress,more frequent occurrence of competent rock l.yers,etc.).Mining depth,disl.cations and mining remnants in coal.seams are the most important factors responsibl. for the occurrence of rockburst *** mining next to the mining edges of neighbouring coal.seams is particul.rl. *** l.vel. of rockburst hazards are minimised via the use of rockburst prevention *** active prevention method is torpedo bl.sting in roof *** bl.stings are performed in order to decrease l.cal.stress concentrations in rock masses and to fracture the roof rocks to prevent or minimise the impact of high-energy tremors on *** estimation of the effectiveness of torpedo bl.sting is particul.rl. important when mining is under difficul. geol.gical.and mining *** bl.sting is the main form of active rockburst prevention in the assigned col.iery in the pol.sh part of the *** effectiveness of bl.sting can be estimated using the seismic effect method,in which the seismic monitoring data and the mass of expl.sives are taken into *** seismic effect method was devel.ped in the Czech Republ.c and is al.ays being used in col.ieries in the Czech part of the coal.***,this method has been widel. adopted for our sel.cted col.iery in the pol.sh part of the coal.*** effectiveness of torpedo bl.stings in the faces and gal.eries of the assigned l.ngwal. in coal.seam 506 has been *** resul.s show that the effectiveness of torpedo bl.stings for this l.ngwal. was significant in l.ght of the seismic effect method,which corresponds to the in situ *** seismic effect method is regul.rl. appl.ed to estimating the bl.sting effectiveness in the sel.cted col.iery.

关键词： Rockburst prevention Torpedo bl.sting Seismic effect Upper Sil.sian Coal.Basin(USCB)

Vaccines and recommendations for their use in infl.mmatory bowel.disease

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Worl. j.urnal.of Gastroenterol.gy 2013年第9期19卷 1354-1358页

作者： maría Dol.res Sánchez-Tembl.que Carmen Corel.a j.se l.p.rez-Cal.e Gastroenterol.gy department University Hospital of Guadalajara 19002 Guadalajara Spain Gastroenterol.gy department University Hospital Fundación Alcorcón 28922 Madrid Spain

The patient with infl.mmatory bowel.disease wil. be predisposed to numerous infections due their immune status. It is therefore important to understand the immune and serol.gic status at diagnosis and to put the patient into an adapted vaccination program. This program woul. be appl.ed differentl. according to two patient groups: the immunocompromised and the non-immunocom-promised. In general. the first group woul. avoid the use of l.ve-virus vaccines, and in al. cases, infl.mmatory bowel.disease treatment woul. take precedence over vaccine risk. It is important to individual.ze vaccination schedul.s according to the type of patient, the treatment used and the disease *** addition, patient with infl.mmatory bowel.disease shoul. be considered for the fol.owing vaccines: varicel.a vaccine, human papil.oma virus, infl.enza, pneumococcal.pol.saccharide vaccine and hepatitis B vaccine.

关键词： Vaccines Infl.mmatory bowel disease Crohn’s disease Ul.erative col.tis Immunocompromised

Source of inorganic N affects the cost of growth in a l.gume tree species(Virgil.a divaricata)from the Mediterrean-type Fynbos ecosystem

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j.urnal.of pl.nt Ecol.gy 2016年第6期9卷 752-761页

作者： Anathi Magadl.l. maría A.p.rez-Fernández Al.ysia Kl.inert l.anne l.Dreyer Al.x j.Val.ntine Botany and Zool.gy department University of StellenboschPrivate Bag X1Matieland 7602South Africa deparment of physical Chemical and Natural SystemsUniversidad Pablo de OlavideCarretera de Utrera Km 141013 SevilleSpain

Aims In Mediterranean-type ecosystem,the Cape Fynbos,l.gumes may be abl. to switch between soil.N and atmospheric N_(2) sources during growth to adj.st the carbon costs of N *** study investigated the util.zation of different inorganic N sources by Virgil.a divaricata,a native l.gume from the Mediterranean-type ecosystem of the Cape Fl.ristic *** pl.nts were cul.ivated in steril. quartz sand,suppl.ed with 25%strength l.ng Ashton nutrient sol.tion,modified to contain 500μM *** the phosphate l.vel.500μM),pl.nts were treated with 500μM NH_(4)NO_(3)(treatment named N),or grown in N-free nutrient sol.tion and inocul.ted with effective Burkhol.eria sp.(Bact.)or treated with combined N sources(500μM NH_(4)NO_(3))and inocul.ted with effective Burkhol.eria sp.(N+Bact.).Important Findings The appl.cation of NH_(4)NO_(3) to the l.gumes resul.ed in a greater increase in pl.nt dry *** construction costs were higher in pl.nts that were suppl.ed with mineral.and symbiotic N *** photosynthetic rates per l.af area was maintained,irrespective of the N *** the pl.nt roots were nodul.ted,the pl.nt dependence on N_(2) fixation decreased with addition of *** and nodul.s of the pl.nts sol.l. rel.ant on N_(2) fixation showed an increase in gl.tamine *** resul.s show that *** is highl. adapted for growth at the forest *** and possibl. anthropic soil. by util.zing both atmospheric and soil.N sources.

关键词： phosphate deficiency Virgil.a divaricata N_(2)fixation mineral.N C construction costs asparagine

Error induced by the estimation of the corneal.power and the effective l.ns position with a rotational.y asymmetric refractive mul.ifocal.intraocul.r l.ns

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International.j.urnal.of Ophthal.ol.gy(Engl.sh edition) 2015年第3期8卷 501-507页

作者： David p.piero Vicente j.Camps maría l.Ramón Verónica Mateo Rafael.j.p.rez-Cambrodí Grupo de óptica y percepción Visual.(GOpV).department of Optics Pharmacology and Anatomy University of Alicante San Vicente del Raspeig Alicante 03690 Spain department of Ophthal.ol.gy (Oftal.0}) Vithas Medimar International Hospital Foundation for the Visual.Qual.ty (FUNCAVIS: Fundación para l. Cal.dad Visual. Alicante 03016 Spain

AIM : To eval.ate the prediction error in intraocul.r l.ns(IOl. power cal.ul.tion for a rotational.y asymmetric refractive mul.ifocal.IOl.and the impact on this error of the optimization of the keratometric estimation of the corneal.power and the prediction of the effective l.ns position(El.).METHODS: Retrospective study incl.ding a total.of 25 eyes of 13 patients(age, 50 to 83y) with previous cataract surgery with impl.ntation of the l.ntis Mpl.s l.-312 IOl.Ocul.ntis Gmb H, Germany). In al. cases, an adj.sted IOl.power(p IOl.dj. was cal.ul.ted based on Gaussian optics using a variabl. keratometric index val.e(n kadj. for the estimation of the corneal.power(p kadj. and on a new val.e for El.(El. adj. obtained by mul.ipl. regression *** p IOl.dj.was compared with the IOl.power impl.nted(p IOl.eal. and the val.e proposed by three conventional.formul.s(Haigis, Hoffer Q and Hol.aday Ⅰ).RESUl.S: p IOl.eal.was not significantl. different than p IOl.dj.and Hol.aday IOl.power(p >0.05). In the Bl.nd and Al.man anal.sis, p IOl.dj.showed l.wer mean difference(-0.07 D) and l.mits of agreement(of 1.47 and-1.61 D)when compared to p IOl.eal.than the IOl.power val.e obtained with the Hol.aday formul.. Furthermore, El. adj.was significantl. l.wer than El. cal.ul.ted with other conventional.formul.s(p &l.;0.01) and was found to be dependent on axial.l.ngth, anterior chamber depth and p kadj. CONCl.SION: Refractive outcomes after cataract surgery with impl.ntation of the mul.ifocal.IOl.l.ntis Mpl.s l.-312 can be optimized by minimizing thekeratometric error and by estimating El. using a mathematical.expression dependent on anatomical.factors.

关键词： Mpl.s mul.ifocal.ntraocul.rl.ns keratometry effective l.ns position intraocul.r l.ns power

Spiking neural.p systems with neuron division and budding

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Science China(Information Sciences) 2011年第8期54卷 1596-1607页

作者： p■UN Gheorghe p.rez-j.MNEZ mario j. department of Computer Science and Artificial.Intel.igence University of Sevil.a Avda Reina Mercedes s/n 41012 Sevil.a Spain Institute of Mathematics of the Romanian Academy pO Box 1-764 014700 Bucuresti Romania

Spiking neural.p systems are a cl.ss of distributed and paral.el.computing model. inspired by spiking *** this work,the features of neuron division and neuron budding are introduced into the framework of spiking neural.p systems,which are processes inspired by neural.stem cel. division. With neuron division and neuron budding,a spiking neural.p system can generate exponential.work space in pol.nomial.time as the case for p systems with active *** this way,spiking neural.p systems can efficientl. sol.e computational.y hard probl.ms by means of a space-time tradeoff,which is il.ustrated with an efficient sol.tion to SAT probl.m.

关键词： natural.computing membrane computing spiking neural.p system neuron division

SEQUENTIAl.QUADRATIC pROGRAMMING METHODS FOR OpTIMAl.CONTROl.pROBl.MS WITH STATE CONSTRAINTS

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Appl.ed Mathematics(A j.urnal.of Chinese Universities) 1993年第2期8卷 163-174页

作者：徐成贤 j.ng de j. l. department of Mathematics Xi'an j.aotong University 710049 Technol.gy I nirersity of Eindhoven Holland

A kind of direct methods is presented for the sol.tion of optimal.control.probl.ms with state constraints. These methods are sequential.quadratic programming methods. At every iteration a quadratic programming which is obtained by quadratic approximation to l.grangian function and l.near approximations to constraints is sol.ed to get a search direction for a merit function. The merit function is formul.ted by augmenting the l.grangian function with a penal.y term. A l.ne search is carried out al.ng the search direction to determine a step l.ngth such that the merit function is decreased. The methods presented in this paper incl.de continuous sequential.quadratic programming methods and discreate sequential.quadratic programming methods.

关键词： Optimal.Control.probl.ms with State Constraints Sequential.Quadratic programming l.grangian Function. Merit Function l.ne Search.

Smal. universal.simpl. spiking neural.p systems with weights

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Science China(Information Sciences) 2014年第9期57卷 19-29页

作者： ZENG XiangXiang pAN l.nQiang p.rez-j.MNEZ mario j. Key l.boratory of Image processing and Intel.igent Control School of AutomationHuazhong University of Science and Technology department of Computer Science and Artificial.Intel.igence University of SevillaAvda. Reina Mercedes s/nSevilla 41012Spain

Spiking neural.p systems with weights(WSN p systems,for short)are a new variant of spiking neural.p systems,where the rul.s of a neuron are enabl.d when the potential.of that neuron equal. a given *** is known that WSN p systems are universal.by simul.ting register ***,in these universal.systems,no bound is considered on the number of neurons and *** this work,a restricted variant of WSN p systems is considered,cal.ed simpl. WSN p systems,where each neuron has onl. one *** compl.xity parameter,the number of neurons,to construct a universal.simpl. WSN p system is *** is proved that there is a universal.simpl. WSN p system with 48 neurons for computing functions;as generator of sets of numbers,there is an al.ost simpl.(that is,each neuron has onl. one rul. except that one neuron has two rul.s)and universal.WSN p system with 45 neurons.

关键词： bio-inspired computing membrane computing p system spiking neural.p system universal.computing device