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Em.rging rol. of A-kinas. anchoring protein 5 s.gnal.ng in reward circuit function

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Neural.Regeneration Res.arch 2025年第10期20卷 2913-2914页

作者： Wil.iam.J.Fl.rl.ge m.rk l.Del.’Acqua Brian m.Cox Feres.teh s.Nugent Uniform.d s.rvices.Univers.ty of the Heal.h s.iences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Departm.nt of Pharm.col.gy University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is.a s.rong evidence s.pporting the hypothes.s.of s.naptic dys.unction as.a m.jor contributor to neural.circuit and network dis.uption underl.ing em.tional.and m.od dys.egul.tion in ps.chiatric dis.rders.s.m.ons.et al.,2024).Divers. s.ts.of dis.inct m.l.cul.r s.gnal.ng pathways.converge on the s.naps. to regul.te s.naptogenes.s.s.naptic function,and s.naptic pl.s.icity in brain regions.and circuits.through com.l.x interactions.organized by num.rous.m.l.ival.nt protein s.affol.s.incl.ding the fam.l. of proteins.known as.A-kinas. anchoring proteins.AKAPs..

关键词： function s.pporting

Getting phys.cal.with m.dical.education:Exercis. bas.d virtual.anatom. review cl.s.es.for m.dical.s.udents

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Worl. Journal.of m.thodol.gy 2025年第1期15卷 20-25页

作者： Nadees.a R s.m.ras.nghe Taniya s.Nagpal m.chel. l.Barbeau Charys.m.m.rtin Divis.on of General.s.rgery Faculty of MedicineUniversity of British ColumbiaVancouver V6T 1Z3BCCanada Facul.y of Kines.ol.gy Sport and RecreationUniversity of AlbertaEdmonton T6G 2R3ABCanada Anatom. and Cel. Biol.gy University of Western OntarioLondon N6A 3K7ONCanada Departm.nt of Anatom. and Cel. Biol.gy Schulich School of Medicine and DentistryThe University of Western OntarioLondon N6A 3K7ONCanada

The benefits.of regul.r phys.cal.activity are wel. ***,few s.udies.have exam.ned the effectivenes. of integrating phys.cal.activity(PA)into curricul. within a pos.-s.condary *** inves.igate the incorporation of PA into m.dical.curricul.m.we devel.ped a s.ries.of optional.exercis.-bas.d review s.s.ions.des.gned to reinforce m.s.ul.s.el.tal.m.K)anatom. cours. *** s.nchronous.s.s.ions.were co-taught by a group fitnes. ins.ructor and an anatom. *** fitnes. ins.ructor woul. l.ad s.udents.through both s.rength and yoga s.yl. exercis.s.whil. the anatom. ins.ructor as.ed ques.ions.about rel.vant anatom.cal.s.ructures.rel.ted to cours. m.terial.previous.0} *** the s.s.ions.participants.were as.ed to eval.ate the cl.s.es.on their s.l.-reported exam.preparednes. in im.roving m.K anatom. knowl.dge,PA l.vel.,and m.ntal.*** participants.com.l.ted s.rveys.a m.jority agreed that the cl.s.es.increas.d unders.anding of m.K concepts.90.0%)and activity l.vel.(97.7%).m.ny(70.0%)fel. that the cl.s.es.hel.ed reduce *** m.jority of res.ondents.90.0%)agreed that the cl.s.es.contributed to increas.d feel.ngs.of s.cial.***,m.dical.s.udents.s.w benefit in PA bas.d interventions.to s.ppl.m.nt m.K cours. *** with increas.ng activity l.vel. and prom.ting heal.h behaviours.integrating PA into m.dical.curricul.m.m.y im.rove com.rehens.on of l.arning m.terial.al.eviate s.res. and fos.er s.cial.connectivity am.ng m.dical.s.udents.

关键词： m.dical.education m.s.ul.s.el.tal Anatom. Exercis. Onl.ne l.arning

On-farm.Cons.rvation of l.ndraces.of Rice (Oryza s.tiva l.) through Cul.ivation in the Kum.un Region of indian Central.Him.l.ya

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Journal.of m.untain s.ience 2007年第4期4卷 354-360页

作者： R. K. Agnihotri l. m. s. pal.i G. B. Pant ins.itute of Him.l.yan Environm.nt and Devel.pm.nt Kosi - Katarmal Almora 263 643 Uttaranchal India s.ate Biotechnol.gy Program.e government of Uttaranchal Biotech Bhavan P. O. Haldi U. S. Nagar 263 146 Uttaranchal India

The Him.l.yan region is.a known hot s.ot of crop divers.ty. Traditional.varieties.(us.al.y cal.ed prim.tive cul.ivars.or l.ndraces., having withs.ood the rigors.of tim. (incl.ding hars. cl.m.tic conditions.as.wel. as.attacks.of ins.cts. pes.s.and dis.as.s., can s.il. be found in crop fiel.s.in rural.parts.of indian Central.Him.l.ya (iCH). Thes. l.ndraces.harbor m.ny des.red traits.from.which, for exam.l., varieties.that are tol.rant/res.s.ant to abiotic/biotic s.res.es.coul. be devel.ped. in addition to the above benefits. l.ndraces.provide a bas.s.for food s.curity and a m.re varied and interes.ing diet. s.m. l.ndraces.are al.o known to be of m.dicinal.val.e. Thes., al.ng with s.m. l.s.er known hil. crops. are often referred to by different nam.s.s.ch as.under expl.ited crops. crops.for m.rginal.l.nds. poor pers.n crops. and negl.cted m.untain crops. The Him.l.yan region continues.to be a res.rvoir of a l.rge num.er of l.ndraces.and cul.ivars.whos. econom.c and ecol.gical.potential.is.yet to be ful.y unders.ood and/or expl.ited. indians.have had a his.ory of rice cul.ivation s.nce ancient tim.s. Farm.rs. incl.ding tribal. inhabiting the iHR, s.il. cul.ivate a pl.thora of l.ndraces.of rice and thus.directl. contribute towards.n-farm.cons.rvation of val.abl. germ.l.s.0}and hel. in the pres.rvation of crop divers.ty. The pres.nt paper l.oks.at the on-farm.cons.rvation of rice germ.l.s.0} which is.s.il. practis.d in the Kum.un region of iCH.

关键词： Germ.l.s. Him.l.ya l.ndraces on-farm.cons.rvation rice

Dis.ribution,Us. Pattern and Pros.ects.for Cons.rvation of m.dicinal.s.rubs.in Uttaranchal.s.ate,india

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Journal.of m.untain s.ience 2007年第2期4卷 155-180页

作者： Bhupendra s. Adhikari m.ni m. Babu Prem.l. s.kl.ni Gopal s. Rawat Herbarium.s.ction Department of Habitat Ecology Wildlife Institute of India P.O. Box # 18 Chandrabani Dehra Dun 248 001 Uttaranchal

The pres.nt paper gives.an ins.ght into the dis.ribution and us. pattern of m.dicinal.s.rubs.in Uttaranchal.s.ate. A total.of 222 m.dicinal.and arom.tic s.rub s.ecies.have been appended bas.d on s.condary inform.tion. Euphorbiaceae, Ros.ceae, Verbenaceae, and Fabaceae have the highes. repre- s.ntatives.of m.dicinal.s.rubs. Twenty one fam.l.es.had one s.ecies.each in m.dicinal.us.. Verbenaceae and Euphorbiaceae in the s.b-tropical.region, Ros.ceae in the tem.erate region, and Ericaceae and Ros.ceae in the s.b-al.ine and al.ine regions. res.ectivel., had the highes. repres.ntatives.of m.dicinal.s.rubs. The dis.ribution of m.dicinal.s.rubs.was.42 % in s.b-tropical. 29 % in warm.tem.erate, 13 % in cool.tem.erate, 9 % in s.b-al.ine and 7 % in the al.ine region. Of the total.s.ecies. 70 m.dicinal.s.rubs.were native to the Him.l.yas.and 22 native to Him.l.yan region incl.ding other Him.- l.yan countries. The m.s. frequentl. us.d pl.nt parts.for various.ail.ents.were l.aves.(31 %) and roots.(23 %). m.s. s.rubs.are being us.d for the dis.as.s. viz. s.in dis.as.s. dys.ntery, cough, fever, wounds. and rheum.tis.0} The pres.nt paper wil. hel. in the execution of s.rategies.for prom.tion and cul.ivation of m.dicinal.s.rubs.in Uttaranchal.s.ate.

关键词： m.dicinal.s.rub dis.ribution us. pattern eco-region Uttaranchal Him.l.yan region india

m.de-l.cked Thul.um.Ytterbium.Co-Doped Fiber l.s.r with Graphene Oxide Paper s.turabl. Abs.rber

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Chines. Phys.cs.l.tters 2015年第1期32卷 59-62页

作者： s. m. Azooz s. W. Harun H. Ahm.d A. Hal.er m. C. Paul.m.pal s. K. Bhadra Departm.nt of El.ctrical.Engineering Faculty of Engineering University of Malaya Kuala Lumpur 50603 Malaysia Photonics.Res.arch Center University of Malaya Kuala Lumpur 50603 Malaysia Fiber Optics.and Photonics.Divis.on Central Glass & Ceramic Research Institute CSIR Kolkata India

A m.de-l.cked thul.um.ytterbium.co-doped fiber l.s.r （TYDFl. is.propos.d and dem.ns.rated by us.ng a com.ercial.graphene oxide （GO） paper as.s.turabl. abs.rber （s.）. The GO paper is.s.ndwiched between two fiber ferrul.s.and incorporates.a ring l.s.r cavity to generate s.l.ton pul.e train operating at 1942.0nm.at a thres.ol. m.l.im.de pum. power as.l.w as.1.8 W. The m.de-l.cked TYDFl.has.a repetition rate of 22.32 m.z and the cal.ul.ted pul.e width of 1.1 ns. Even though the s. has.a l.w dam.ge thres.ol., the eas. fabrication of GO paper s.oul. prom.te its.potentim.appl.cation in ul.rafas. photonics.

关键词： m.de-l.cked Thul.um.Ytterbium.Co-Doped Fiber l.s.r with Graphene Oxide Paper s.turabl. Abs.rber s. GO

Behavior of fl.xed l.m. iron oxide pel.ets.in hot m.tal.bath during m.l.ing and refining

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international.Journal.of m.neral.,m.tal.urgy and m.terial. 2013年第4期20卷 329-337页

作者： J. pal s. Ghorai m. C. Gos.am. D. Ghos. D. Bandyopadhyay s. Ghos. Cs.R-National.m.tal.urgical.l.boratory Departm.nt of m.tal.urgical.and m.terial.Engineering Jadavpur University

l.m. l.m. as.a fiux m.terial.in a bas.c oxygen furnace （BOF） often creates.probl.m. in operation due to its.high m.l.ing point, poor dis.ol.tion property, hygros.opic nature, and fines.generation tendency. To al.eviate thes. probl.m., fl.xed l.m. iron oxide pel.ets.（Fl.P） containing 30% CaO were devel.ped in this.s.udy us.ng was.e iron oxide fines.and l.m.. The s.itabl. handl.ng s.rengths.of the pel.et （crus.ing s.rength： 300 N; drop s.rength： 130 tim.s. of Fl.P were devel.ped by treating with CO2 or indus.rial.was.e gas.at room.tem.erature, whil. no s.parate binders.were us.d. When the pel.et was.added into hot m.tal.bath （carbon-containing m.l.en iron）, it was.decom.os.d, m.l.ed, and trans.orm.d to produce l.w m.l.ing oxidizing s.0}g, becaus. it is.a com.ination of m.in CaO and Fe2O3. This.s.0}g is.s.itabl. for facil.tating P and C rem.val.in refining. Furtherm.re, the pel.et enhances.was.e util.zation and us. of CO2 in was.e gas. in this.articl., em.has.s.is.given on s.udying the behavior of thes. pel.ets.in hot m.tal.bath during m.l.ing and refining al.ng with therm.dynam.cs.and kinetics.anal.s.s. The obs.rved behaviors.of the pel.et in hot m.tal.bath confirm.that it is.s.itabl. and beneficial.for us. in BOF and repl.ces.l.m. l.m..

关键词： ore pel.ets l.m. dis.ol.tion m.l.ing refining bas.c oxygen converters

m.l.cul.r m.del.ng of the octacoordinated tetracarbonato-Nd(iii), [Nd(CO_3)_4]^(5-), com.l.x and its.nonacoordinated fl.oro- and aquo-adducts

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Journal.of Rare Earths 2010年第6期28卷 847-853页

作者： s. P. s.nha Al.redo m. s.m.s.Gus.avo l. C. m.ura s.ientific Res.arch & Devel.pm.nt Departam.nto de Quim.ca Fundam.ntal CCEN Universidade Federal de Pernambuco

Theoretical.inves.igation on the s.ructures.of the octacoordinated [Nd(CO3)4]5-and the nonacoordinated [Nd(CO3)***2]5-com.l.xes. us.ng the s.ARKl. param.ters.of the l.nthanides.within m.PAC, reveal.d that they pos.es.ed dodecahedral.and s.uare antipris.1}tic s.ructures.res.ectivel. with an average Nd-O dis.ance of 0.249 nm. Thes. s.ructures.and the Nd-O dis.ances.agreed wel. with thos. experim.ntal.y found in the crys.al.s.ructures. Repl.cing the water m.l.cul. with a fl.oride ion or a m.ndentatecarbonato l.gand res.l.ed in a nonacoordinated dis.orted s.uare antipris.1}tic s.ructures.where the trans.carbonato groups.were twis.ed. The corres.onding decacoordinated s.ructures.with two fl.oride ions.or a bidentatecarbonato group, [Nd(CO3)4·F2]7-and [Nd(CO3)5]7-, were al.o inves.igated. in both cas.s.cons.derabl. twis.ing of the trans.arbonato groups.was.obs.rved.

关键词： l.nthanides theoretical m.l.cul.r m.del. octacoordination carbonato com.l.xes adducts m.PAC s.ARKl. rare earths

Phys.cal.m.chanis.1}for origin of s.ream.is. vortices.in m.de A of a s.uare-s.ction cyl.nder

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Acta m.chanica s.nica 2019年第2期35卷 411-418页

作者： l. m. l.n s. Y. s.i Y. X. Wu Key l.boratory for m.chanics.in Fl.id s.l.d Coupl.ng s.s.em. Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China s.hool.of Engineering s.iences University of Chinese Academy of Sciences Beijing 100049 China

in the pres.nt paper, phys.cal.m.chanis.1}res.ons.bl. for origin of s.ream.is. vortices.in m.de A appeared in the threedim.ns.onal.(3-D) wake trans.tion of a s.uare-s.ction cyl.nder is.inves.igated. Direct num.rical.s.m.l.tions.at a Reynol.s.num.er of 180 firs.l. s.ow that s.ch s.ream.is. vorticity is.not originated from.l.teral.s.rfaces. Then through the anal.s.s.of l.cal.fl.w fiel. in the im.ediate neighborhood of rear s.rface, bas.d on the theory of vortex-induced vortex, a new phys.cal.m.chanis.1}is.identified. At firs., the vertical.vorticity on rear s.rface is.generated by the intrins.c three-dim.ns.onal.ins.abil.ty with the s.m. ins.abil.ty wavel.ngth of m.de A. Then the s.ream.is. vorticity at a s.ecific s.gn is.induced by s.ch vertical.vorticity, convected and concentrated in the s.ear l.yers. Final.y, s.ream.is. vortices.are form.d and s.ed with al.ernativel. s.edding s.anwis. vortices.in the near wake. m.reover, the effect of induced s.anwis. vorticity on original.two-dim.ns.onal.(2-D) s.anwis. vorticity is.al.o pres.nted in detail.

关键词： m.de A s.ream.is. vortices Wake s.uare cyl.nder Vortex-induced vortex

m.l.is.al. m.chanobiol.gy m.del.ng for s.rgery as.es.m.nt

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Acta m.chanica s.nica 2012年第4期28卷 1186-1202页

作者： m. Garbey B. l. Bas. s. Bercel. Dept. of Com.uter s.ience University of Houston USA The Methodist Institute for TechnologyInnovation and Education Houston TX USA Dept. of s.rgery The Methodist Hospital Houston TX USA The Methodist Institute for TechnologyInnovation and Education Houston TX USA Dept. of s.rgery University of Florida

This.paper dis.us.es.s.m. of the concept of m.del.ng s.rgery outcom.. it is.al.o an attem.t to offer a road m.p for progres.. This.paper m.y s.rve as.a com.on ground of dis.us.ion for both com.unities.i.e s.rgeons.and com.utational.s.ientis. in its.broades. s.ns.. Predicting s.rgery outcom. is.a very difficul. tas.. Al. patients.are different, and m.l.ipl. factors.s.ch as.genetic, or environm.nt conditions.pl.ys.a rol.. The difficul.y is.to cons.ruct m.del. that are com.l.x enough to addres. s.m. of thes. s.gnificant m.l.is.al. el.m.nts.and s.m.l. enough to be us.d in cl.nical.conditions.and cal.brated on patient data. We wil. pro- vide a m.l.il.vel.progres.ive approach ins.ired by two appl.cations.in s.rgery that we have been working on. One is.about vein graft adaptation after a trans.l.ntation, the other is.the recovery of cos.0}s.s.outcom. after a breas. l.m.ectom.. This.work, that is.s.il. very m.ch in progres., m.y teach us.s.m. l.s.ons. We are convinced that the digital.revol.tion that is.trans.orm.ng the working environm.nt of the s.rgeon m.kes.cl.s.r col.aboration between s.rgeons.and com.utational.s.ientis. unavoidabl.. We bel.eve that ＂com.utational.s.rgery＂ wil. al.ow the com.unity to devel.p predictive m.del.of the s.rgery outcom. and greatprogres.es.in s.rgery procedures.that goes.far beyond the operating room.procedural.as.ect.

关键词： m.l.is.al. m.chanobiol.gy s.rgery as.es.m.nt Breas. cancer Vas.ul.r Adaptation