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Effect of col.-work.ng on corrosion induced damage in l.g joints

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Defence Tech.ol.gy（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath.M.N Ch.k.ath.l. Murth. h. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical.Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

l.g joints are preferred joineries for transferring h.avy l.ads to parent components in aerospace *** experience corrosion due to environmental.conditions,improper surface finish.s and rubbing displ.cement between th. pin and *** causes damage of different sizes and sh.pes near th. *** degradation due to corrosion-induced damage is model.ed as a th.ough.pit at one of th. identified critical.l.cations th.ough.stress *** effect of th.s pit on fatigue crack.initiation l.fe is ***-h.l. is pre-stressed by col.-work.ng and th. benefits of inducing pl.stic wak. on th. intended performance of th. l.g joint during th. damages due to corrosion are brough. out and compared with.non-col.-work.d *** anal.sis is performed on th.s l.g joint with.*** resul.s obtained h.gh.0}gh. th. benefits of col.-work.ng and th. meth.dol.gy can be extended to damage growth.and anal.se th. effect of surface treatments for better structural.integrity of components of aerospace veh.cl.s.

关键词： l.g joint Corrosion Crack.initiation Col.-work.ng Structural.integrity

CD4^(+)T cel.s produce IFN-I to l.cense cDC1s for induction of cytotoxic T-cel. activity in h.man tumors

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Cel.ul.r & Mol.cul.r Immunol.gy 2024年第4期21卷 374-392页

作者： Xin l.i Daniël.C.de Groot Marij J.P.Wel.ers Tom de Wit El.en Sch.ama h.ns van Eenennaam Sask.a J.Santegoets Timo Oosenbrug Annemarth. van der Veen Joris l.Vos Ch.rl.tte l.Zuur Noel.F.C.C.de Miranda h.inz Jacobs Sjoerd h.van der Burg Jannie Borst Yanl.ng Xiao Department of Immunol.gy Leiden University Medical CenterLeidenThe Netherlands Oncode Institute Leiden University Medical CenterLeidenThe Netherlands Department of Tumor Biol.gy and Immunol.gy The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Medical.Oncol.gy Oncode InstituteLeiden University Medical CenterLeidenThe Netherlands IMMIOS B.V. OssThe Netherlands Division of Medical.Oncol.gy The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Otorh.nol.ryngol.gy l.iden University Medical.Center LeidenThe Netherlands Department of Path.l.gy Leiden University Medical CenterLeidenThe Netherlands

CD4^(+)T cel.s can"h.l."or"l.cense" conventional.type 1 dendritic cel.s(cDC1s)to induce CD8^(+)cytotoxic T l.mph.cyte(CTl.anticancer responses,as proven in mouse *** recentl. identified cDC1s with.a transcriptomic imprint of CD4^(+)T-cel. h.l.,specifical.y in T-cel.-infil.rated h.man cancers,and th.se cel.s were associated with.a good prognosis and response to PD-1-targeting ***,we del.neate th. mech.nism of cDC1 l.censing by CD4^(+)T cel.s in *** CD4^(+)T cel.s produce IFNβvia th. STING path.ay,wh.ch.promotes Mh.-I antigen(cross-)presentation by cDC1s and th.reby improves th.ir abil.ty to induce CTl.anticancer *** cooperation with.CD40 l.gand(l.,IFNβal.o optimizes th. costimul.tory and oth.r functions of cDC1s required for CTl.response ***-I-producing CD4^(+)T cel.s are present in diverse T-cel.-infil.rated cancers and l.k.l. del.ver“h.l.”signal. to CTl. l.cal.y,according to th.ir transcriptomic profil. and col.cal.zation with.h.l.ed/l.censed”cDCs and tumor-reactive CD8^(+)T *** agreement with.th.s scenario,th. presence of IFN-I-producing CD4^(+)T cel.s in th. TME is associated with.overal. survival.and th. response to PD-1 ch.ck.oint bl.ck.de in cancer patients.

关键词： CD4^(+)T-cel. h.l. cDC1 l.censing IFN-I signal.ng CD40 costimul.tion (cross-)presentation CTl.priming Tumor control

CT Th.esh.l.s for Spinal.Bone Mineral.Attenuation to Prioritize El.gibl. Ol.er Women for Osteoporosis Screening

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Open Journal.of Radiol.gy 2024年第2期14卷 92-101页

作者： Seo Yeon k. Orite Bryn h.guch. h.o-Ch.n Yoon l.na h. Gimber St. El.zabeth. Medical.Center Brighton MA USA University of Cal.fornia Irvine CA USA k.iser Permanente Division of Research Oakland CA USA Department of Diagnostic Imaging Hawaii Permanente Medical Group Honolulu HI USA

Introduction: Computed tomograph. (CT) measurements of bone mineral.attenuation may be a useful.means to identify ol.er women wh. sh.ul. be prioritized for bone mineral.density screening. Meth.ds: We compared bone mineral.attenuation as measured in th. l. vertebra of CT studies to th. resul.s of dual.energy x-ray absorptiometry (DEXA) studies to determine wh.t CT attenuation th.esh.l.s migh. yiel. a reasonabl. combination of sensitivity and specificity for th. detection of osteoporosis. Th. study was l.mited to women between th. ages of 65 and 75 years wh. h.d a DEXA study and a CT th.t incl.ded th. l. or adjacent vertebra performed with.n 3 years of th. DEXA study. Resul.s: Th.re were 1226 women in th.s study, of wh.m 452 (38%) h.d osteoporosis based on a T-score ≤ −2.5 by DEXA. Th.re were 830 CT studies performed with.contrast and 396 studies wh.ch.were performed with.ut contrast. Th.re was a statistical.y significant difference in th. mean h. of th.se studies performed with.ut contrast compared to th.se with.contrast (unenh.nced mean 103 h. versus 125 h., p h.esh.l.s provided th. most appropriate combination of sensitivity and specificity for th. detection of osteoporosis wh.n comparing CT studies performed with.ut or with.IV contrast and wh.n al. th. CT data were used in aggregate. Concl.sion: Different th.esh.l.s appear necessary wh.n using th. mean CT vertebral.attenuation to identify ol.er women for preferential.referral.for DEXA studies.

关键词： Osteoporosis Bone Mineral.Attenuation CT Th.esh.l.

Fish.on-Ch.ps:unveil.ng neural.processing of ch.mical. in smal. animal. th.ough.precise fl.idic control

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Neural.Regeneration Research 2024年第11期19卷 2351-2353页

作者： Samuel.k.h.Sy h. k. Division of Neurol.gy Department of Medicine and TherapeuticsFaculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina l. k. Sh.ng Institute of h.al.h.Sciences Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Department of El.ctrical.and El.ctronic Engineering Faculty of EngineeringThe University of Hong KongPok Fu LamHong Kong IslandHong Kong Special Administrative RegionChina Advanced Biomedical.Instrumentation Center Hong Kong Science ParkPak Shek KokNew TerritoriesHong Kong Special Administrative RegionChina Margaret k.l.Ch.ung Research.Center for Management of Park.nsonism Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina l.u Tat-ch.en Research.Center of Brain Degenerative Diseases in Ch.nese Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Geral. Ch.a Neuroscience Institute The Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina

Precise ch.mical.cue presentation al.ngside advanced brainwide imaging tech.iques is important to th. study of ch.mosensory processing in ***,th. dynamic nature of ch.mical.carrying media,such.as water or air,poses a significant ch.l.enge for del.vering h.gh.0}-control.ed ch.mical.fl.w to an animal.***,contact-based cue manipul.tion and del.very easil. sh.ft th. position of th. animal.subject,wh.ch.is often undesirabl. for h.gh.qual.ty brain ***,more advanced interfacing tool. th.t al.gn with.th. diverse range of body part sizes of an animal.ranging from micrometer-scal. neurons to meter-l.ng l.mbs,are much.*** is particul.rl. crucial.wh.n deal.ng with.dimensions th.t are beyond th. reach.of conventional.experimental.tool..

关键词： deal.ng precise sizes

Efficient guiding and focusing of intense l.ser pul.e using periodic th.n sl.ts

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Matter and Radiation at Extremes 2024年第4期9卷 29-39页

作者： l.Xu T.W.h.ang k.Jiang C.N.Wu h.Peng P.C.h.n R.l. h.B.Zh.o C.T.Zh.u Sh.nzh.n k.y l.boratory of Ul.raintense l.ser and Advanced Material.Tech.ol.gy Center for Intense Laser ApplicationTechnologyand College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118People’s Republic of China

Sl.ts h.ve been widel. used in l.ser-pl.sma interactions as pl.sma optical.components for generating h.gh.h.rmonic l.gh. and control.ing l.ser-driven particl. ***,we propose and demonstrate th.t periodic th.n sl.ts can be regarded as a new breed of optical.el.ments for efficient focusing and guiding of intense l.ser *** fundamental.ph.sics of intense l.ser interaction with.th.n sl.ts is studied,and it is reveal.d th.t rel.tivistic effects can l.ad to enh.nced l.ser focusing far beyond th. pure diffractive focusing *** addition,th. interaction of an intense l.ser pul.e with.periodic th.n sl.ts mak.s it feasibl. to ach.eve mul.ifol. enh.ncement in both.l.ser intensity and energy transfer efficiency compared with.conventional.*** resul.s provide a novel.meth.d for manipul.ting ul.ra-intense l.ser pul.es and sh.ul. be of interest for many l.ser-based appl.cations.

关键词： l.ser pul.e intense

Val.dation of th. TOPAS Monte-Carl. Code of th. Off-Fiel. Dose of a 6 MV Synergy l.nac

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Journal.of Biosciences and Medicines 2024年第7期12卷 38-54页

作者： k.djo Joel.Fabrice N’Guessan Ibrah.ma Sak.o Bogbé D. l. h. Gogon Department of Ph.sics and Ch.mistry Faculty of Sciences and Technology Iba Der Thiam University of This This Senegal International.Cancer Center of Dak.r Dakar Senegal Department of Ph.sics Faculty of Sciences and Technology Flix Houphouet Boigny University of Abidjan Abidjan Cte dIvoire

Th. risk.of radiation-induced second cancer and th. l.te tissue l.ss due to Off-fiel. doses in radioth.rapy remain a serious concern. Monte Carl. (MC) simul.tion is currentl. one of th. most accurate meth.ds for cal.ul.ting th.se doses. MC simul.tion model.based on th. Particl. Simul.tion Tool.(TOPAS) h.s been devel.ped to simul.te th. off-fiel. dose of an El.k.a Synergy l.near accel.rator (l.nac) emitting 6 MV ph.tons. Measurements were tak.n in a water ph.ntom using an ionization ch.mber to val.date th.s model. Th. Percentage Depth.Dose (PDD) at th. depth.of 0.0, 5.0, 10.0 and 15.0 cm from th. beam axis for a 10 × 10 cm2 fiel. size was measured and simul.ted. Off-fiel. dose profil.s at th. depth.of 1.5 (dmax), 5.0 and 10.0 cm for fiel. sizes of 5 × 5, 10 × 10, 15 × 15, and 20 × 20 cm2 respectivel. were measured and simul.ted. Comparison of measured and simul.ted off-fiel. dose val.es sh.wed a good agreement. Th. average gamma passing rate of th. PDDs and profil.s curves for off-fiel. doses were 87.5% and 98.11% respectivel.. Th. l.cal.dose difference based on th. PDD curve between th. measured and simul.ted was l.ss th.n 6.0 % for al. l.cations. For al. fiel. size considered in th.s study, th. average difference between profil. curves for off-fiel. dose measured and simul.ted was 9.1%. PDDs and Profil.s curves for off-fiel. dose simul.tion uncertainties were l.ss th.n 2.0% and 1.0% respectivel.. TOPAS-MC simul.tion model.devel.ped is a good representation of our 6 MV l.nac El.k.a Synergy for assessing off-fiel. dose, wh.ch.woul. be th. primary cause of some secondary cancers.

关键词： Radioth.rapy Off-Fiel. Dose Secondary Cancer TOPAS-MC Simul.tion Dosimetry

Cool.wh.te l.gh. and tunabl. mul.icol.r emission from Tb^(3+)/Dy^(3+)co-activated gl.sses under different excitations for Wl.Ds

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Journal.of Rare Earth. 2024年第1期42卷 46-56,I0002页

作者： l.Vijayal.k.h.i k.Naveen k.mar Jong Dae Baek Department of Automotive Engineering Yeungnam UniversityGyeongsanGyeongbuk38541Republic of Korea Department of Mech.nical.Engineering Yeungnam UniversityGyeongsan38541Republic of Korea

A set of co-doped(Tb^(3+)/Dy^(3+))l.th.um zinc borate(l.B)gl.sses were devel.ped by mel. *** structural.eval.ation was performed for synth.sized gl.ssy *** Dy^(3+)and Tb^(3+)individual.y doped gl.sses exh.bit intense yel.ow and green l.minescence bands at 575 nm(^(4)F_(9/2)→^(6)h.(13/2))and543 nm(^(5)D_(4)→^(7)F_(5)),*** sensitization effect of Dy^(3+)on Tb^(3+)was anal.zed by increasing th. Tb^(3+)content with.respect to th. optimum Dy^(3+)content(0.5 mol.)in Dy^(3+)/Tb^(3+).Th. spectral.overl.y of Dy^(3+)l.minescence and Tb^(3+)absorption profil.s,Dy^(3+)/Tb^(3+)Pl.spectra under different excitations 352,362,376,and 385 nm,sh.rtening decay l.fetimes of Dy^(3+)in Dy^(3+)/Tb^(3+)co-activated gl.sses,energy transfer(ET)parameters,ch.omaticity coordinates and th.ir corresponding correl.ted temperatures al. h.l. to expl.in ET from Dy^(3+)to Tb^(3+).At 385 nm of Dy^(3+)excitation,th. optimized co-activated(0.5Dy^(3+)+1.0Tb^(3+)):l.B gl.ss displ.ys cool.wh.te l.gh. *** non-radiative ET from Dy^(3+)to Tb^(3+)is dominated by el.ctric dipol.-dipol. interaction and its ET efficiency was cal.ul.ted to be 63%.At th. same time,reverse ET from Tb^(3+)to Dy^(3+)was al.o *** sh.ft in col.r coordinates from dominant yel.ow to greenish.yel.ow,green and wh.te l.gh. emission suggests th.t Dy^(3+)/Tb^(3+)coactivated l.B gl.sses can be a potential.candidate for UV converted mul.icol.r and wh.te l.gh. emitting devices.

关键词： Rare earth. Ph.tol.minescence Energy transfer Spectral.overl.p Decay l.fetime Mul.icol.r emitting l.Ds

Empirical.model.for fusion cross sections of Ca-induced reactions

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Ch.nese Ph.sics C 2024年第3期48卷 126-132页

作者： Reddi Rani.l.N.Sowmya k.N Sridh.r h.C.Manjunath. M.M.Armstrong Arasu Department of Ph.sics St.Joseph's College(Autonomous)Affiliated to Bharathidasan UniversityTiruchirappalli620002TNIndia Department of Ph.sics Govt.First.Grade CollegeChikkaballapur-562101KarnatakaIndia Department of Ph.sics Govt.First.Grade CollegeMalur-563160KarnatakaIndia Department of Ph.sics Govt.First.Grade CollegeDevanahalli-562110KarnatakaIndia

A new empirical.formul. for th. astroph.sical.S-factor h.s been suggested as a function of th. Coul.mb interaction parameter,center of mass energy,and barrier *** 22 fusion reactions with.^(40,48)Ca as projectil.s were considered for different targets,l.ading to compound nucl.i with.atomic and mass numbers varying between 40≤Z≤≤Z≤112 and 88≤A≤27888≤A≤278,*** fusion cross-sections h.ve been estimated using th. geometric factor,th. Gamow-Sommerfiel. factor,and th. empirical.formul. for th. *** study's findings sh.wed better agreement with.th.se of avail.bl. experiments wh.n compared to Wong's *** present work.l.ads to a smal.er standard deviation val.e th.n Wong's formul. wh.n used to correl.te th. experimental.data of cal.ium-induced fusion ***'s formul. provides a good approximation of fusion cross-sections wh.n th. center of mass energy is bel.w th. fusion barrier wh.n compared to above th. fusion barrier.

关键词： fusion cross-sections Wong formul. Gamow-Sommerfiel.-factor Geometric-factor S-factor

Spal.ing ch.racteristics of h.gh.temperature treated granitic rock.at different strain rates

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Journal.of Rock.Mech.nics and Geotech.ical.Engineering 2024年第4期16卷 1280-1288页

作者： l.F.Fan Q.h.Yang X.l.Du Th. k.y l.boratory of Urban Security and Disaster Engineering of Ministry of Education Beijing University of TechnologyBeijing100124China

Th. dynamic spal.ing ch.racteristics of rock.are important for stabil.ty anal.sis in rock.*** paper presented an experimental.investigation on th. dynamic spal.ing ch.racteristics of granite with.different temperatures and strain rates.A series of dynamic spal.ing tests with.different impact vel.cities were conducted on th.rmal.y treated granite at different *** dynamic spal.ing strength. of granite with.different temperatures and strain rates were determined.A model.was proposed to correl.te th. dynamic spal.ing strength.of granite,h.gh.temperature and strain *** resul.s sh.w th.t th. spal.ing strength.of granite decreases with.increasing ***,th. spal.ing strength.of granite with.a h.gh.r strain rate is l.rger th.n th.t with.a l.wer strain *** proposed model.can describe th. rel.tionsh.p among dynamic spal.ing strength.of granite,h.gh.temperature and strain rate.

关键词： Dynamic spal.ing ch.racteristics h.gh.temperature Strain rate Dynamic l.ading Granite