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Identification,Phylogeny and Expressional Profiles of Peptidoglycan Recognition Protein(PGRP)Gene Family in Sinonovacula constricta

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Journal of Ocean University of China 2022年第4期21卷 1051-1060页

作者： MENG Yiping lüliyuan DAI Wenfang ZHANG Weiwei lIN Zhihua DONG Yinghui School of Marine Sciences Ningbo UniversityNingbo 315010China Zhejiang Key laboratory of Aquatic Germplasm Resource College of Biological&Environmental SciencesZhejiangWanli UniversityNingbo 315100China Ninghai Institute of Mariculture Breeding and Seed Industry Zhejiang Wanli UniversityNinghai 315604China

Peptidoglycan recognition protein(PGRP)plays a vital role in invertebrate innate immunity system as a specific pattern recognition receptor for *** possess various PGRP systems for self-defense;however,it has not been characterized in razor clam Sinonovacula *** this study,eight PGRP coding sequences were identified and analyzed from *** genome,which are designated as ScPGRP-S1,ScPGRP-S2,ScPGRP-S3,ScPGRP-S4,ScPGRP-S5,ScPGRP-S6,ScPGRP-S7,*** results of molecular evolutionary analyses showed that all eight ScPGRP genes were highly conserved and exhi-bited a typical PGRP/amidase_2 domain as PGRP genes in other ***,the presence of signal peptides was predicted in ScPGRP-S2,ScPGRP-S3 and ScPRP-S6,while a transmembrane structure only existed in ***,a tertiary struc-ture analysis indicated that no disulfide bond was observed in ScPGRP-S5 and *** mRNA transcripts analysis of ScPGRPs revealed that the high expression patterns of ScPGRP-S1 and ScPGRP-S4 were found in mantle,adductor muscle and foot,while those of ScPGRP-S2,ScPGRP-S3 and ScPGRP-S6 were observed in ***,the temporal expression profiles of ScPGRPs in the hepatopancreas were analyzed by qPCRlogy-and-microbiology/real-time-polymerase-chain-reaction>after Gram-negative Vibrio parahaemolyticus and Gram-positive Staphylococcus aureus *** mRNA expressions of ScPGRP-S2,ScPGRP-S3 and ScPGRP-S6 could be induced by ***-rahaemolyticus and ***,our findings indicated that ScPGRPs were involved in the immune defense against invaders,which constituted a comprehensive understanding of the potential role of PGRP genes in ***.

关键词： Sinonovacula constricta peptidoglycan recognition protein gene family gene expression

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Candy or poison: Plant metabolites as swing factors against microbes

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Molecular Plant 2024年第9期17卷 1341-1343页

作者： liyuan Wang Yu Xia Yingnan Hou Shanghai Collaborative Innovation Center of Agri-Seeds School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China

Plant metabolites play crucial roles in plant-microbe interactions,influencing compatibility with different microbial species and modulating both symbiotic and pathogenic *** synthesize two categories of metabolites:primary and secondary metabolites,each serving specific functions in plant physiology and *** metabolites,including sugars,lipids,nucleotides,amino acids,and organic acids,are essential for plant growth and ***,these metabolites also serve as nutrient sources for *** invasion of devastating pathogens relies heavily on their ability to effectively acquire primary metabolites from host *** instance,transcriptional activator-like effectors from Xanthomonas and Ralstonia are known to trigger the transcription of OsSWEET genes,which encode sugar transporters.

关键词： invasion sugar Plant

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Influence of pile-raft connection on lateral performance of combined pile-raft foundations adjacent to tunnelling

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Underground Space 2024年第2期15卷 176-187页

作者： Wenbo Gu liyuan Tong Huangsong Pan Hongjiang li Institute of Geotechnical Engineering Southeast UniversityNanjing 211189China Department of Architecture and Architectural Engineering Kyoto UniversityKyoto 6158540Japan School of Architecture and Civil Engineering Xihua UniversityChengdu 610039China

The lateral response of combined pile-raft foundations(CPRFs)adjacent to tunnel excavation is a challenging problem owing to the complexity of the pile-raft *** current engineering practices,the impact of these connections on the lateral performance of CPRFs is frequently overlooked,despite their *** address this issue,this study conducted three-dimensional finite element analyses to evaluate the contribution of pile-raft connections to the tunnelling-induced lateral performance of CPRFs in saturated *** the analysis,both passive and active loading at the pile head could be considered by varying the tunnel *** parameter studies,such as relative pile-raft modulus,pile embedded modulus,pile embedded depths,and pile shaft skin friction,were conducted to determine the optimal design parameters for *** results indicate that pile-raft connections significantly affect the tunnellinginduced deflections and bending moments of pile *** by the results,a simplified design method,the pile-raft connection coefficient Kc was ***,the pile-head restraint percentage was established to make a relationship with the pile-raft connection coefficient in order to assess the pile-raft connection and guide the pile-raft *** this paper,the recommended range value of Kc is 10–200 and the range value of pile-head restraint percentage is 24%–42%.

关键词： Combined pile-raft foundations Tunnelling lateral performance Pile-raft connection

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Design of distributed dynamic absorbers for vibration suppression of panel structures

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Acta Mechanica Sinica 2024年第7期40卷 164-180页

作者： liyuan li Bin li Zehua Xu School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China China Aero-Polytechnology Establishment Beijing 100028China

Distributed dynamic absorbers have many advantages such as wide frequency bandwidth for vibration suppression,strong detuning adaptability,and high system stability,making them very suitable for the vibration and noise control of continuous ***,they have broad application prospects in various fields such as transportation,aviation,and ***,there are still many challenges in the engineering applications of distributed dynamic absorbers for vibration suppression,including the engineering realization of the optimal damping of traditional optimal coherence dynamic absorbers,and the engineering applicability of the finite periodic array dynamic *** on the damping material properties obtained by the dynamic mechanical analyzer tests,this paper establishes the finite element model of the cantilever-beam-type dynamic absorber with constrained damping layers,aiming to realize the accurate determination of the optimal *** are conducted by attaching the traditional dynamic absorbers with the optimal damping to a thin-walled panel with four clamped *** show that the vibration of the panel is well suppressed,with the reduction of the frequency response peak larger than 14 dB and the reduction ratio of RMS larger than 58%within 500 ***,the periodically arrayed dynamic absorbers are designed according to the bandgap regulation *** tuning behavior of the arrayed dynamic absorbers by changing designing parameters is *** vibration reduction effect of arrayed dynamic absorbers is compared with that of the traditional dynamic absorbers under the same mass ratio through *** indicate that the arrayed dynamic absorbers are easier to design,and have a similar reduction effect on the modal vibration of the thin panel as the traditional dynamic absorbers within a narrow frequency range near the natural frequency,while they perform unsatisfactory in a broad ***,if t

关键词： Distributed dynamic absorbers Engineering realization of the optimal damping Vibration suppression low-frequency and broadband

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Preparation and Characterization of pH-Responsive Charge Reversal Nanocomposite for miRNA Delivery

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Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 1048-1052页

作者：余丹 YE liyuan lI Binbin MOU Fangzhi 殷义霞 State Key laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Hainan Institute Wuhan University of TechnologySanya 572000China Biomedical Materials and Engineering Research Center of Hubei Province Wuhan University of TechnologyWuhan 430070China

pH-responsive charge reversal loaded miRNA nanocomposite was prepared by electrostatic *** morphology,particle size and zeta potential of the nanocomposites were analyzed by transmission electron microscopy and dynamic light *** synthesis of the polymer was analyzed by^(1)*** zeta-potential changes and cellular uptake effects of the nanocomplexes under different pH environments were *** experimental results show that the surface morphology of the nanocomposite is spherical,and the average particle size is about 135 *** the pH value of the solution gradually decreases,the surface charge of the nanocomposite reverses from negative charge to positive charge(from-9.4 to+17.1 mV).Cellular uptake mediated by pH-responsive nanocomposite is selective for tumor cells,and the cellular uptake effect in tumor cells at pH 6.5 was approximately 3 times higher than that at pH *** pH responsive charge reversal nanocomposite has promising application prospects for gene delivery in the weak acid environment of tumors.

关键词： charge conversion siRNA delivery pH responsive cancer therapy

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Unique electromagnetic wave absorber for three-dimensional framework engineering with copious heterostructures

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Journal of Materials Science & Technology 2024年第3期170卷 129-139页

作者： liyuan Yu Qianqian Zhu Zhiqiang Guo Yuhang Cheng Zirui Jia Guanglei Wu Institute of Materials for Energy and Environment State Key Laboratory of Bio-fibers and Eco-textilesCollege of Materials Science and EngineeringQingdao UniversityQingdao 266071China College of Chemistry and Chemical Engineering Qingdao UniversityQingdao 266071China

In order to obtain high-performance electromagnetic wave absorbers,the adjustment of structure and components is *** on the above requirements,this system forms a three-dimensional frame structure consisting of MXene and transition metal oxides(TMOs)through efficient electrostatic *** three-dimensional network structure has rich heterojunction structures,which can cause a large amount of interface polarization and conduction losses in incident electromagnetic *** structures cause multiple reflections and scattering of electromagnetic waves,which is also an important reason for further increasing electromagnetic wave *** the doping ratio is 1:1,the system has the best impedance matching,the maximum effective absorption bandwidth(EAB max)can reach 5.12 GHz at 1.7 mm,and the minimum reflection loss(Rl_(min))is-50.30 dB at 1.8 *** provides a reference for the subsequent formation of 2D-MXene materials into 3D materials.

关键词： MXene Three-dimensional frame Heterojunction structure Conduction loss Electromagnetic wave absorption

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Disturbance failure mechanism of highly stressed rock in deep excavation:Current status and prospects

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 611-627页

作者： Tao Wang Weiwei Ye liyuan liu Kai liu Naisheng Jiang Xianhui Feng School of Civil and Resources Engineering University of Science and Technology BeijingBeijing 100083China Key laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China Department of Engineering Science University of OxfordParks RoadOxford OX13PJUK School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China

This article reviews the current status on the dynamic behavior of highly stressed rocks under ***,the experimental apparatus,methods,and theories related to the disturbance dynamics of deep,high-stress rock are reviewed,followed by the introduction of scholars’research on deep rock deformation and failure from an energy ***,with a backdrop of highstress phenomena in deep hard rock,such as rock bursts and core disking,we delve into the current state of research on rock microstructure analysis and residual stresses from the perspective of studying the energy storage mechanisms in ***,the current state of research on the mechanical response and the energy dissipation of highly stressed rock formations is briefly ***,the insufficient aspects in the current research on the disturbance and failure mechanisms in deep,highly stressed rock formations are summarized,and prospects for future research are *** work provides new avenues for the research on the mechanical response and damage-fracture mechanisms of rocks under high-stress conditions.

关键词： deep rock with high stress highly stressed rock rock failure residual stress energy release

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The real estate time-stamping and registration system based on Ethereum blockchain

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Blockchain(Research and Applications) 2024年第1期5卷 119-132页

作者： liyuan Zhang limian Ci Yonghong Wu Benchawan Wiwatanapataphee School of Electrical Engineering Computing&Mathematical ScienceCurtin UniversityKent StreetPerth6102WAAustralia

In recent years,there has been a growing interest in real estate investments that utilize blockchain *** real estate investments usually involve third-party intermediaries for verifying and recording informal real estate *** paper proposes a blockchain-based real estate investment model and presents a detailed description of the real estate register authentication aspect of the *** model uses blockchain technology to create tamper-evident records of real estate transactions and provide secure authentication and verification for informal real estate ***,each real estate transaction is recorded in a block,and all transaction records are kept on the *** means that inventors can access these transaction records and verify their authenticity and *** system can also use smart contracts to automate the process of real estate transactions,which further improves transaction efficiency and reduces ***,the model’s timestamp and authentication mechanism can eliminate third-party intermediaries and ensure the authenticity and validity of real estate transactions through distributed ledgers and verification ***,blockchain-based real estate systems offer advantages of security,transparency,efficiency,and cost *** ongoing blockchain advancements,these systems are expected to play a crucial role in future real estate investment transactions.

关键词： Blockchian technology Smart contract Real estate investment Time-stamping and registration system

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Beyond the arylamine convention

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Science China Materials 2024年

作者： liyuan Han State Key laboratory of Metal Matrix Composites Shanghai Jiao Tong University

Inverted perovskite solar cells（PSCs） offer several advantages including superior durability, compatibility with tandem structures, and thus market-integration potentials[1-4]. Research on inverted PSCs has gained momentum with the introduction of molecule-based hole-selective contacts, significantly enhancing device power conversion efficiencies（PCEs）.

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Deep understanding of typical CNT morphology on the microstructure and mechanical properties of 2D carbon/carbon composites

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Journal of Materiomics 2024年第2期10卷 396-407页

作者： Jiajia Sun Qiang Song liyuan Han Xuemin Yin Hejun li State Key laboratory of Solidification Processing Shaanxi Key Laboratory of Fiber Reinforced Light Composite MaterialsNorthwestern Polytechnical UniversityXi'an710072China

For the inadequate interlaminar strength of 2D carbon/carbon(C/C)composite,in-situ grown carbon nanotubes(CNTs)reinforcing strategy was put forward to strengthen the interlaminar matrix at the nanoscale and inhibit the interlaminar *** morphology is an essential factor in influencing the enhancement ***,the influence of in-situ grown CNT morphology on the microstructure and mechanical properties of C/C composite was deeply *** radially-aligned straight CNTs could induce the formation of highly-ordered pyrolytic carbon(PyC),while PyC in randomly-distributed curved CNTs concentrated area exhibits an isotropic ***,radially-aligned straight CNTs show better improvement on the flexural and shear strength of C/C *** to the fine structural characterization and finite element simulation,the influence mechanism of CNT morphology was *** morphology can influence the stress distribution in the PyC protective layer,and compared with radially-aligned straight CNTs,randomly-distributed curved CNTs induce higher tensile stress in the PyC protective layer,which has a detrimental impact on the flexural and shear properties of C/C *** work provides novel insights into the effect of CNT morphology on the microstructure and mechanical properties of C/C composites,which gives a basis for the structural design and preparation of CNTs reinforced C/C composites.

关键词： CNT morphology C/C composite Microstructure Mechanical properties

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