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Earth and Planetary Physics 2021年第5期5卷 397-406页

作者： Cristiano Max Wrasse Cosme Alexandre Oliveira Barros Figueiredo Diego Barros Hisao Takahashi Alexander JoséCarrasco luiz Fillip Rodrigues Vital láysa cristina araujo resende Fábio Egito Geângelo de Matos Rosa Antonio Hélder Rodrigues Sampaio Space Weather Division National Institute for Space Research(INPE)São Josédos CamposBrazil University of los Andes(UlA) MéridaVenezuela State Key laboratory of Space Weather Beijing 100190China Federal University of Campina Grande(UFCG) Campina GrandeBrazil Federal Institute for Education Science and Technology Baiano(IF Baiano)Bom Jesus da LapaBrazil

OI 630.0 nm airglow observations,from a new observatory at Bom Jesus de lapa,were used to study the interaction between EPBs(Equatorial Plasma Bubbles)and the MSTID(Medium-Scale Traveling Ionospheric Disturbance)over the Northeast region in *** the night of September 16 to 17,2020,an EPB was observed propagating eastward,in an apparent fossil stage,until it interacted with a dark band electrified MSTID(e MSTID).After the interaction,four EPBs merged,followed by an abrupt southward development and *** of the data suggests that an eastward polarization electric field,induced by the dark band e MSTID,forced the EPB into an upward drift,growing latitudinally along the magnetic field lines and then bifurcating.

关键词： Equatorial Plasma Bubbles Medium-Scale Traveling Ionospheric Disturbance ionosphere thermosphere EPB and MSTID interaction

Sarcopenia and Anemia Are Predictors of Poor Prognostic in Cervical Cancer Patients

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 693-704页

作者： leandro Santos de araujo resende Francine Vilela de Amorim Miguel Soares Conceição Rodrigo Menezes Jales Patrick Nunes Pereira luis Otávio Sarian Glauco Baiocchi Sophie Derchain Agnaldo lopes da Silva Filho Department of Gynecology and Obstetrics Botucatu Medical School S&#227o Paulo State University UNESP S&#227o Paulo Brazil Department of Health Sciences University of Sao Francisco S&#227o Paulo Brazil Department of Obstetrics and Gynecology School of Medical Science State University of Campinas (UNICAMP) Campinas Brazil Department of Gynecologic Oncology AC Camargo Cancer Center Sao Paulo Brazil Department of Gynecology and Obstetrics School of Medicine of the Federal University of Minas Gerais Belo Horizonte Brazil

Objective: Evaluate pretreatment sarcopenia and anemia as prognostic factors in women undergoing treatment for cervical cancer (CC) with concurrent chemoradiotherapy (CCRT). Methods: 151 women with CC were analysed in this cohort study. Pretreatment computed tomography (CT) images were analysed to assess skeletal muscle index (SMI). Hazard ratios (HR) and multivariate Cox proportional HR were used to analyse association between low SMI, age, body mass index (BMI), haemoglobin levels, histological type, and International Federation of Gynaecology and Obstetrics (FIGO) stage with PFS and OS. Results: A total of 151 patients were included, 53 (35.1%) presented pretreatment sarcopenia;51 (34%) stage I/II and 100 (66%) stage III/IV. Among those patients in advanced stage (III/IV) 37 (70%) (p = 0.28) were sarcopenic at the beginning of treatment. Sarcopenia was associated with worse progression-free survival (PFS) and overall survival (OS) in our cohort [HR 0.97 (p = 0.01)] [HR 0.73 (p = 0.001)], as well as anemia [HR 0.73 (p = 0.001)] [HR 0.78 (p = 0.001)]. linear regression models indicated that despite showing no association with age, neutrophil or platelet counts, sarcopenia was associated with pretreatment anemia levels (p = 0.01). After a multivariate analysis, only haemoglobin (anemia) and complete CCRT remained associated with PFS and OS. Sarcopenia and anemia were associated with worse PFS and OS in FIGO stage I/II. Conclusion: Pretreatment sarcopenia was significantly associated with low haemoglobin levels. Anemia and incomplete CCRT were independently associated with poor prognosis in women with CC. Pretreatment sarcopenia, as low SMI, was a predictor of poor prognostic in early stages of CC.

关键词： Cervical Cancer Sarcopenia Anemia Chemoradiotherapy

Inherited Fanconi syndrome

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World Journal of Pediatrics 2023年第7期19卷 619-634页

作者： Anna luiza Braga Albuquerque Rafael dos Santos Borges Ana Flavia Conegundes Erika Emmylaine dos Santos Frederico Moreira Man Fu Clara Tavares araujo Pedro Alves Soares Vaz de Castrol Ana cristina Simoes e Silva Interdisciplinary laboratory of Medical Investigation Unit of Pediatric NephrologyFaculty of MedicineFederal University of Minas Gerais(UFMG)Belo HorizonteBrazil Department of Pediatrics Faculty of MedicineUFMGAlfredo Balena Avenue1902Nd FloorRoom#281Belo HorizonteMG 30130-100Brazil

Background Fanconi-Debré-de Toni syndrome(also known as Fanconi renotubular syndrome,or FRST)profoundly increased the understanding of the functions of the proximal convoluted tubule(PCT)and provided important insights into the pathophysiology of several kidney diseases and drug *** sources We searched Pubmed and Scopus databases to find relevant articles about *** review article focuses on the physiology of the PCT,as well as on the physiopathology of FRST in children,its diagnosis,and *** FRST encompasses a wide variety of inherited and acquired PCT alterations that lead to impairment of PCT *** children,FRST often presents as a secondary feature of systemic disorders that impair energy supply,such as lowe's syndrome,Dent's disease,cystinosis,hereditary fructose intolerance,galactosemia,tyrosinemia,Alport syndrome,and Wilson's *** rare,congenital causes of FRST greatly impact the morbidity and mortality of patients and impose diagnostic ***,its treatment is diverse and considers the ability of the clinician to identify the correct etiology of the *** The early diagnosis and treatment of pediatric patients with FRST improve the prognosis and the quality of life.

关键词： Cystinosis Fanconi syndrome Fanconi renotubular syndrome Fanconi-Debre-de Toni syndrome Proximal tubule Renal tubular transport-Rickets

Qualitative Comparison between the Brazilian labeling Program for Buildings and the Portuguese Energy Certification System for Buildings:Proposals for Improving Brazilian Regulations

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Energy Engineering 2021年第3期118卷 615-629页

作者： Jaime Francisco de Sousa resende Andrea lucia Teixeira Charbel Teresa cristina Bessa Nogueira Assunção Graduate Program in Energy Engineering Federal University of São João del ReiSão João del ReiBrazil Department of Thermal and Fluid Sciences Federal University of São João del ReiSão João del ReiBrazil Department of Electrical Engineering Federal University of São João del ReiSão João del ReiBrazil

Buildings represent a significant share of the world’s energy consumption,and the sector has drawn the attention of governments,which have adopted policies to reduce energy *** Certifications of Energy Efficiency in Buildings stand out as one possible solution to achieve this goal,employed in several countries *** European Union presents advanced energy assessment programs for buildings,being a reference and model for several other regulations in the *** Energy Certification System for Buildings(SCE)of Portugal is considered a success case,reflected in the significant number of energy certificates *** Brazilian labeling Program for Building(PBE Edifica),first launched in 2009,does not find a broad application today in the Brazilian *** work shows a synthesis of the European Energy Performance of Buildings Directive(EPBD)and the Brazilian and Portuguese regulations’history.A qualitative comparison is made between the SCE and the PBE Edifica to verify a European and a developing country’s regulations with a certain degree of cultural and climatic *** this comparison,proposals are made for improvements to Brazilian certification,seeking to improve its energy planning and energy policy concerning its building *** suggestions for improvement presented may also be appropriate for other developing countries that have started and have not yet successfully implemented their energy certification programs in buildings.

关键词： Energy efficiency energy policy building labeling energy certification improvement proposals

Fraud investigation in commercial coffee by chromatography

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Food Quality and Safety 2018年第3期2卷 121-133页

作者： Víctor de Carvalho Martins Ronoel luiz de Oliveira Godoy Ana cristina Miranda Senna Gouvêa Manuela cristina Pessanha de araujo Santiago Renata Galhardo Borguini Elaine cristina de Oliveira Braga Sidney Pacheco luzimar da Silva de Mattos do Nascimento Departamento de Tecnologia de Alimentos Instituto de TecnologiaUniversidade Federal Rural do Rio de JaneiroCEP 23890-000Seropédica-RJBrazil laboratório de Cromatografia líquida Embrapa Agroindústria de AlimentosCEP 23020-470Rio de Janeiro-RJBrazil Centro de Tecnologia Instituto de QuímicaUniversidade Federal do Rio de JaneiroCEP 22290-180Rio de Janeiro-RJBrazil

Coffee is currently the second largest commodity on the world market today,and there is great concern about the quality of the beans exported from producer countries to Europe and *** such as using blends of different species and adding low-cost raw materials,such as chicory,corn,and soybean,impair the sensory and functional characteristics of the drink made from roasted and ground coffee *** is a need to adopt more efficient analytical methods than the microscopy technique currently *** first chromatographic method used to determine fraud was reported in *** method used paper chromatography to differentiate between coffee and chicory based on the free reducing *** of the 1980s,different methods involving high-performance liquid chromatography and gas chromatography were developed in order to demonstrate geographic authenticity,distinction between species,occurrence of adulteration,and the presence of defective beans by determining the monosaccharides,oligosaccharides,tocopherols,fatty acids,volatiles,diterpenes,sterols,and phenolic substances,among *** far as the authors know,there are no papers published in the literature that have compiled such an extensive set of information about these chromatographic methods as *** the last 2 years,there has been a trend to develop analytical methods for ultra-performance liquid chromatography coupled with tandem mass spectrometry to confirm fraud in coffee,due to high sensitivity and selectivity.

关键词： adulteration coffee chromatographic methods carbohydrates volatile substances

A large Vaginal Bulge Might Not Be a Genital Prolapse

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Open Journal of Obstetrics and Gynecology 2018年第4期8卷 362-367页

作者： Natasha Ferreira Teixeira Meletti Susana cristina Aidé Viviani Fialho Fabiana resende Rodrigues Carlos Augusto Faria Hospital Universitário Antonio Pedro Universidade Federal Fluminense(UFF)Rio de Janeiro(RJ)Brazil

Vaginal tumors, whether benign or malignant, are rare. They include fibroepithelial polyps (FEPs), which are benign lesions originating in mesenchymal cells, comprised of a core of connective tissue covered by squamous epithelium. They are usually small and asymptomatic. When symptomatic or very large, they may cause bleeding, genital discomfort or the presence of a bulge in the vagina. In the last case, they may be mistaken for a genital prolapse. Although their physiopathology is still not clearly understood, the presence of hormonal receptors and the occurrence of FEPs during the use of hormone therapy or pregnancy suggest that changes in the stroma of these lesions may be induced by hormones. We report on the case of a patient who presented with a vaginal bulge and was referred to the urogynecology outpatient ward with a diagnosis of genital prolapse, which had actually a large fibroepithelial polyp on the posterior vaginal wall.

关键词： Diagnosis Pathology Pelvic Organ Prolapse Vaginal Neoplasms

Pyoderma gangrenosum affecting the mouth

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Open Journal of Stomatology 2013年第2期3卷 142-145页

作者： Marcos Martins Curi Camila lopes Cardoso Daniel Henrique Koga cristina Zardetto Sergio Rocha araujo Department of Stomatology Hospital Santa CatarinaSao PauloBrazil Department of Stomatology Bauru School of DentistryUniversity of Sao PauloBauruSao PauloBrazil

Pyoderma gangrenosum is a rare ulcerative cutaneous disorder commonly associated with systemic diseases such as inflammatory bowel diseases. This paper reports a case of pyoderma gangrenosum affecting the mouth and the skin associated with ulcerative colitis. A Medline search in English literature from 1961 to 2012 revealed only 11 documented cases of pyoderma gangrenosum with oral involvement. Previous reported cases of oral cavity involvement have shown that the most common sites of manifestation are the tongue, palate, and tonsillar fauces. This case emphasizes the importance of including inflammatory bowel diseases and their manifestations in the differential diagnosis of ulcerative lesions in the oral cavity.

关键词： Pyoderma Gangrenosum Oral Manifestation Inflammatory Bowel Disease Ulcerative Colitis

Comparison of Interfacial and Foaming Properties of Soy and Whey Protein Isolates

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Journal of Food Science and Engineering 2012年第7期2卷 376-381页

作者： Cecilia Abirached Claudia Alejandra Medrano Aria Claudia araujo Patrick Moyna Maria cristina Anon luis Alberto Panizzolo Food Science and Technology Departament Facultad de Quimica Universidad de la Republiea Montevideo 11800 Uruguay DEPTEQ Facultad de Quimica Universidad de la Republica Montevideo 11800 Uruguay CIDCA-CONICET- UNlP La Plata 1900 Argentina

Antioxidant Protective Effects of the Resveratrol on the Cardiac and Vascular Tissues from Renal Hypertensive Rats

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Open Journal of Medicinal Chemistry 2012年第3期2卷 61-71页

作者： Joyce cristina de Oliveira Carla Renata Kitanish Antonietto Angélica cristina Scalabrini Talita Sanches Marinho larissa Pernomian JoséWilson NCorrêa Carolina Baraldi araujo Restini School of Nutrition University of Ribeirao PretoRibeirao PretoBrazil School of Pharmaceutical Sciences University of Ribeirao PretoRibeirao PretoBrazil Department of Physics and Chemistry Faculty of Pharmaceutical Sciences from Ribeirao PretoLaboratory of PharmacologyUniversity of Sao PauloRibeirão PretoBrazil Federal University of Amazonas ManausBrazil School of Medicine Animal Experimental LaboratoryUniversity of Ribeirao PretoRibeirao PretoBrazil

Background: Accumulating reactive oxygen species (ROS) is involved in cellular signaling and function disturbances due to the oxidative stress, which contributes to several diseases. The consequences of ROS activity represent an im-portant mechanism on the pathogenesis of vascular diseases, such as hypertension. Increased blood pressure observed in renal hypertension of the 2 kidneys-1 clip (2K-1C) model involves increased ROS levels in the cardiovascular system. Resveratrol, a polyphenolic compound primarily found in red wine, has many biological and pharmacological proper-ties. Considering the antioxidant properties of resveratrol, the present study was aimed to investigate the effects of the chronic treatment with resveratrol on cardiovascular system from renal hypertensive rats. Results: 2K-1C hypertension presented increased blood pressure, which was reduced at the end of the fifth week of resveratrol treatment. The cardiac hypertrophy index and the basal levels of ROS in rat aortic rings were also reduced by resveratrol treatment. Conclusions: The present findings clearly show the protective effects from resveratrol on the blood pressure, the car-diac growth and the vascular ROS generation in renal hypertension.

关键词： Hypertension Aorta Superoxide Resveratrol Phenylephrine Reactive Species of Oxygen(ROS)

Multimodal Stratified Approach for Prevention of Thromboembolism in Patients Undergoing Total Hip Arthroplasty

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Open Journal of Orthopedics 2018年第12期8卷 429-442页

作者： Elmano de araujo loures Glauco Mendonca Rocha Daniel Naya loures Isabel cristina Goncalves leite Clarice Naya loures University Hospital of the Federal University of Juiz de Fora Juiz de Fora MGBrasil Rio Branco Medical Center Juiz de Fora-MGBrasil School of Medicine of the Federal University of Juiz de Fora Juiz de Fora-MGBrasil Sao Paulo Federal University Sao Paulo-SPBrasil

Objective: To demonstrate the efficacy and safety of a multimodal stratified approach for prevention of thromboembolism in patients undergoing primary total hip arthroplasty. Method: A longitudinal retrospective clinical study of a cohort of 341 individuals undergoing total hip arthroplasty between March 2008 and July 2016. Of these, 242 patients met the criteria for inclusion in the study. Individuals with a history of deep vein thrombosis or pulmonary thromboembolism, thrombophilia, hypercoagulation conditions, and chronic users of anticoagulants before surgery received enoxaparin at a dose of 40 mg/day for 21 days. For the other group, acetylsalicylic acid was prescribed at a dose of 200 mg/day for 30 days. All patients had surgical risk assessed by the American Anesthesiology Association classified as I or II, and underwent regional anesthesia, effective hydration, the same protocol of early postoperative rehabilitation, and the use of compression stockings. Drug cost analysis was performed based on the Brasíndice. To date, there are no publications in PubMed and Scielo on this subject regarding the Brazilian population. Results: The need for blood transfusion in the enoxaparin group was higher and the overall complication and hemorrhagic rates were also significantly higher (p less than enoxaparin. Conclusion: In patients without predisposing factors to thromboembolism and undergoing primary total hip arthroplasty, the multimodal approach with acetylsalicylic acid seems to be effective, with low cost and a low rate of complications.

关键词： Anticoagulation Thromboembolism Total Hip Arthroplasty