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Dual-frequency piezoelectric micromachined ultrasound transducer based on polarization switching in ferroelectric thin films

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Microsystems & Nanoengineering 2023年第5期9卷 233-243页

作者： Jin Soo Park Soo Young Jung Dong Hun Kim Jung Ho Park Ho Won jang Tae Geun Kim Seung-Hyub Baek Byung Chul Lee Bionics Research Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea Department of Electrical Engineering Korea UniversitySeoul 02841Republic of Korea Center for Electronic Materials Korea Institute of Science and TechnologySeoul 02792Republic of Korea Department of Material Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolUniversity of Science and Technology(UST)Seoul 02792Republic of Korea KHU-KIST Department of Converging Science and Technology Kyung Hee UniversitySeoul 02447Republic of Korea

Due to its additional frequency response,dual-frequency ultrasound has advantages over conventional ultrasound,which operates at a specific frequency ***,a tunable frequency from a single transducer enables sonographers to achieve ultrasound images with a large detection area and high *** facilitates the availability of more advanced techniques that simultaneously require low-and high-frequency ultrasounds,such as harmonic imaging and image-guided *** this study,we present a novel method for dual-frequency ultrasound generation from a ferroelectric piezoelectric micromachined ultrasound transducer(PMUT).Uniformly designed transducer arrays can be used for both deep low-resolution imaging and shallow high-resolution *** switch the ultrasound frequency,the only requirement is to tune a DC bias to control the polarization state of the ferroelectric *** vibration of the PMUT membrane strongly depends on the polarization state,producing low-and high-frequency ultrasounds from a single excitation *** strategy for dual-frequency ultrasounds meets the requirement for either multielectrode configurations or heterodesigned elements,which are integrated into an ***,this technique significantly reduces the design complexity of transducer arrays and their associated driving circuits.

关键词： piezoelectric ferroelectric enable

Recurrent massive bleeding due to dissecting intramural hematoma of the esophagus: Treatment with therapeutic angiography

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World Journal of Gastroenterology 2009年第41期15卷 5232-5235页

作者： Jaejun Shim Jae Young jang Young Hwangbo Seok Ho Dong Joo Hyeong Oh Hyo Jong Kim Byung-Ho Kim Young Woon Chang Rin Chang Department of Internal Medicine Kyung Hee University School of Medicine Hoegi-dong 1 Dongdaemoongu Seoul 130-702 South Korea Department of Diagnostic Radiology Kyung Hee University School of Medicine Hoegi-dong 1 Dongdaemoon-gu Seoul 130-702 South Korea

Spontaneous or traumatic intramural bleeding of the esophagus, which is often associated with overlying mucosal dissection, constitutes a rare spectrum of esophageal injury called dissecting intramural hematoma of the esophagus (DIHE). Chest pain, swallowing diffi culty, and minor hematemesis are common, which resolve spontaneously in most cases. This case report describes a patient with spontaneous DIHE with recurrent massive bleeding which required critical management and highlights a potential role for therapeutic angiography as an alternative to surgery.

关键词： Esophagus Intramural hematoma Therapeutic angiography

Effects of Heat Treatment in N2 and Se Atmosphere on the Densification of Nanoparticle Derived Cu(In,Ga)Se2 Absorber Layer

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Effects of Heat Treatment in N2 and Se Atmosphere on the Den...

Neuroprotective effects of Suhexiang Wan on the in vitro and in vivo models of Parkinson’s disease

第十五届国际光伏科学与工程大会

作者： Ki-Hyun Kim Se-Jin Ahn Young-Gab Chun Byung-Ok Park kyung-Hoon Yoon Solar Cells Research Center Korea Institute of Energy Research 71-2 Jang-dong Yuseong-gu Daejeon 305-343 Korea Dept.of Inorganic Materials Engineering Kyungpook National University 1370 Sankyuk-dong Puk-ku Daegu 702-701 Korea

Spray-deposited Cu(In,Ga)Se (CIGS) absorber layers were heat-treated in N and Se atmosphere, respectively, in order to get a dense CIGS absorber layer for solar cells application. Heat treatment in N gas was designed to facilitate the growth of CIGS nanoparticle only by thermal energy, while that in Se vapor by thermal energy and Se induced thermo-chemical effects at the same time. A large number of pores existed in the as-sprayed absorber layer were still remained even after heat-treated in N atmosphere at 500℃for 1 h. On the other hand, heat treatment in Se vapor led to the formation of large particles up to 1μm, demonstrating that Se vapor seems to play a critical role in the growth of CIGS nanoparticles and hence the densification of nanoparticle derived CIGS layer.

关键词： Solar Cell Cu(InGa)Se2 Absorber Nanoparticle Densification

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Journal of Traditional Chinese Medicine 2019年第6期39卷 800-808页

作者： Liu Quanfeng Sang Heon Kim Yung-Wei Sung Sok Cheon Pak Wonwoong Lee Jongki Hong Jaehwan jang Kyoung Sang Cho Songhee Jeon Byung-Soo Koo Department of Oriental Medicine Dongguk UniversityGyeogju38066Republic of Korea Department of Oriental Neuropsychiatry Graduate School of Oriental MedicineDongguk UniversityGyeonggi-do 10326Republic of Korea College of Pharmacy Kyung Hee UniversitySeoul 02447Republic of Korea School of Biomedical Sciences Charles Sturt UniversityBathurstNew South Wales2795Australia Department of Biological Sciences Konkuk UniversitySeoul 05029Republic of Korea Department of Biomedical Sciences Center for Creative Biomedical Scientists at Chonnam National UniversityGwangju 61469Korea

OBJECTIVE:To examine the role of KSOP1009(a modified formulation of Suhexiang Wan essential oil)in an animal model of Parkinson's disease(PD)induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine(MPTP)***:Cell toxicity,apoptosis,and reactive oxygen species(ROS)levels were analyzed in the human neuroblastoma cell line SH-SY5 *** that,changes in animal behavior and tyrosine hydroxylase(TH)protein levels in the substantia nigra(SN)of MPTP-injected mice were *** different doses of KSOP1009(30,100,and 300 mg/kg,n=8 for each group)were administered daily for 7 d before MPTP injection and 14 d after MPTP injection,totaling 21 ***:MPP+,the active metabolite of MPTP,decreased the viability of SH-SY5 Y cells,whereas KSOP1009 alleviated MPP+-induced ***1009(10 and 50 mg/m L)reduced MPP+-induced ROS generation compared with the control *** with 1 m M MPP+increased the percentage of depolarized/live cells,whereas KSOP1009 intake at a dose of 10 mg/m L decreased the percentage of these *** mean latency to fall in the rotarod test was reduced in mice treated with MPTP compared with the control ***,mice receiving three different doses of KSOP1009 performed better than MPTP-treated ***-treated mice were more hesitant and took longer to traverse the balance beam than the control *** contrast,KSOP1009-treated mice performed significantly better than MPTPtreated ***,the KSOP1009-treated groups had a significantly higher number of TH-positive neurons in the lesioned SN and significantly higher expression of TH in the striatum than the MPTP-treated *** treatment strongly induced Jun-N-terminal kinase(JNK)activation,whereas KSOP1009 suppressed MPTP-induced JNK *** addition,KSOP1009 intake reversed the decrease in the phosphorylation levels of c AMP-response element-binding protein in the brain of MPTP-treated ***1009 also restored the decrease in dopaminergic

关键词： Parkinson disease 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mitochondria Reactive oxygen species Suhexiang Wan

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Effect of ZnO Layers as Front TCO and Back Reflector in Superstrate pin μc-Si:H and a-Si:H/μc-Si:H Thin-film Solar Cells

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Effect of ZnO Layers as Front TCO and Back Reflector in Supe...

Risk factors for local recurrence after en bloc endoscopic submucosal dissection for early gastric cancer

第十五届国际光伏科学与工程大会

作者： Jeong Chul Lee Sang Won Jeon Junsin Yi Sae Jin Ahn Jae Ho Yun Seok Ki Kim Jinsoo Song kyung Hoon Yoon Solar Cells Research Center Korea Institute of Energy Research 71-2 Jang-dong Yuseong-gu Daejeon 305-343 Korea School of Information and Communication Engineering Sungkyunkwan University

This paper presents the light trapping effect by various front and back ZnO layers in silicon thin-film solar cells. The haze ratio in textured front ZnO layer does not have direct correlation with jsc. The μc-Si:H and a-Si:H/μc-Si:H tandem solar cells prepared on textured ZnO:Al with small feature size (low haze ratio) give higher spectral response throughout whole wavelength range. The a-Si:H top cells act as a buffering layer between front textured ZnO and μc-Si:H layer. By this buffering effect, the carrier recombination by defects, observed in μC-Si:H single pin cells, is suppressed in a-Si:H/μc-Si:H tandem cells. As back reflection materials, doped and undoped ZnO layers with various thickness are incorporated with Ag back metal. In order to prevent reverse diode formation, thickness of undoped ZnO should be thin. However, this thin ZnO is not effective to improve light trapping by internal reflection of red/IR light. In case of doped ZnO, thinner layer gives higer red/IR response due to reduced free carrier absorption.

关键词： thin-film solar cells light trapping, ZnO μc-Si:H tandem back reflector

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World Journal of Gastrointestinal Endoscopy 2016年第7期8卷 330-337页

作者： Ju Yup Lee Kwang Bum Cho Eun Soo Kim kyung Sik Park Yoo Jin Lee Yoon Suk Lee Byoung Kuk jang Woo Jin Chung Jae Seok Hwang Department of Internal Medicine Keimyung University School of Medicine

AIM: To investigate factors related to recurrence following en bloc resection using endoscopic submucosal dissection(ESD) in patients with early gastric cancer(EGC). METHODS: A total of 1121 patients(1215 lesions) who had undergone ESD for gastric neoplasia between April 2003 and May 2010 were retrospectively reviewed. Data from 401 patients(415 lesions) were analyzed, following the exclusion of those who underwent piecemeal resection, with deep resection margin invasion or lateral margin infiltration, and diagnosed with benign lesions. RESULTS: Local recurrence after en bloc ESD was found in 36 cases(8.7%). Unclear resection margins, long procedure times, and narrow safety margins were identified as risk factors for recurrence. Lesions located in the upper third of the stomach showed a higher rate of recurrence than those located in the lower third of the stomach(OR = 2.9, P = 0.03). The probability of no recurrence for up to 24 mo was 79.9% in those with a safety resection margin ≤ 1 mm and 89.5% in those with a margin > 1 mm(log-rank test, P = 0.03). CONCLUSION: Even in cases in which en bloc ESD is performed for EGC, local recurrence still occurs. To reduce local recurrences, more careful assessment will be needed prior to the implementation of ESD in casesin which the tumor is located in the upper third of the stomach. In addition, clear identification of tumor boundaries as well as the securing of sufficient safety resection margins will be important.

关键词： Early gastric cancer Endoscopic mucosal resection Recurrence En bloc resection Endoscopic submucosal dissection

Endothelial progenitor cell differentiation using cryopreserved,umbilical cord blood-derived mononuclear cells

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Acta Pharmacologica Sinica 2007年第3期28卷 367-374页

作者： Jun-ho jang~(2,5) Sun-kyung KIM~(3,5) Jeong-eun CHOI~3 Young-jin KIM~3 Hyun-woo LEE~2 Seok-yun KANG~2 Joon-seong PARK~2 Jin-hyuk CHOI~2 Ho-yeong LIM~4 Hugh C KIM~(2,6)2 Department of Hematalogy-Oncology,Ajou University,School of Medicine,Suwon 442749,Korea 3 Biomedical Research Institute,LifeCord,Suwon 442749,Korea 4 Division of Hematology-Ontology,Department of Medicine,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul 135710,Korea DepartmentofHematology-Oncology AjouUniversitySchoolofMedicineSuwon442749Korea BiomedicalResearchInstitute LifeCordSuwon442749Korea SamsungMedicalCenter SungkyunkwanUniversitySchoolofMedicineSeoul135710Korea

Aim:To investigate the endothelial differentiation potentiality of umbilical cordblood(UCB),we induced the differentiation of endothelial progenitor cells(EPC)from cryopreserved UCB-derived mononuclear cells(MNC).Methods:MNC fromcryopreserved UCB and peripheral blood(PB)were cultured in M199 medium withendothelial cell growth supplements for 14 *** were characterized by RT-PCR,flow cytometry,and immunocytochemistry *** proliferation of differen-tiated EPC was studied by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide(MTT)assay,and vascular endothelial growth factor(VEGF)concentra-tion was measured using an ELISA *** of UCB-derived EPC werecompared with those of PB-derived ***:A number of round-shapedcells were loosely attached to the bottom after 24 h culture,and numerous spindle-shaped cells began to appear from the round-shaped ones on d *** cellsexpressed endothelial markers such as,Flt-1/VEGFR-1,ecNOS,VE-cadherin,vonWillebrand factor,and secreted VEGE The patterns of endothelial markers of EPCfrom PB and UCB did not show striking *** results of the prolifera-tion and secretion of VEGF were also ***:We successfully cul-tured UCB cells stored at -196℃ into cells with the quality of endothelial *** EPC could be used for angiogenic therapeutics by activating adjacentendothelial cells and enhancing angiogenesis.

关键词： cord blood endothelial cells cryopreserved

Diagnostic value of PIVKA-Ⅱ and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma

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World Journal of Gastroenterology 2015年第13期21卷 3928-3935页

作者： Seung In Seo Hyoung Su Kim Won Jin Kim Woon Geon Shin Doo Jin Kim kyung Ho Kim Myoung Kuk jang Jin Heon Lee Joo Seop Kim Hak Yang Kim Dong Joon Kim Myung Seok Lee Choong Kee Park Department of Internal Medicine Hallym University Medical CenterSeoul 134-701South Korea Digestive Disease Center Hallym University Medical CenterSeoul 134-701South Korea Department of Surgery Hallym University Medical CenterSeoul 134-701South Korea

AIM: To determine the cutoff values and to compare the diagnostic role of alpha-fetoprotein(AFP) and prothrombin induced by vitamin K absence-Ⅱ(PIVKA-Ⅱ) in chronic hepatitis B(CHB).METHODS: A total of 1255 patients with CHB, including 157 patients with hepatocellular carcinoma(HCC), 879 with non-cirrhotic CHB and 219 with cirrhosis without HCC, were retrospectively enrolled. The areas under the receiver operating characteristic(AUROC) curves of PIVKA-Ⅱ, AFP and their combination were calculated and ***: The optimal cutoff values for PIVKA-Ⅱ and AFP were 40 m AU/m L and 10 ng/m L, respectively, for the differentiation of HCC from nonmalignant CHB. The sensitivity and specificity were 73.9% and 89.7%, respectively, for PIVKA-Ⅱ and 67.5% and 90.3% for AFP, respectively. The AUROC curves of both PIVKA-Ⅱ and AFP were not significantly different(0.854 vs 0.853, P = 0.965) for the differentiation of HCC from nonmalignant CHB, whereas the AUROC of PIVKA-Ⅱ was significantly better than that of AFP in patients with cirrhosis(0.870 vs 0.812, P = 0.042). When PIVKA-Ⅱ and AFP were combined, the diagnostic power improved significantly compared to either AFP or PIVKA-Ⅱ alone for the differentiation of HCC from nonmalignant CHB(P < 0.05), especially when cirrhosis was present(P < 0.05).CONCLUSION: Serum PIVKA-Ⅱ might be a better tumor marker than AFP, and its combination with AFP may enhance the early detection of HCC in patients with CHB.

关键词： Hepatitis B virus Hepatocellular carcinoma Alpha-f

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世界建筑导报 2020年第3期35卷 6-11页

作者：无景进正宋承熙张淑容金吉妍辛恩金金贤金辛宇森塞尔吉奥·皮罗内(摄影) 金正恩(摄影) 郑锡门(摄影) 履露斋金孝晩建筑师事务所不详

纪念性场地大约20年前,韩国政府在江南举办了“房博会”,建造了这座低层住宅的“世博小镇”,小镇的每一处建筑都是由当时韩国著名的建筑师精心设计的。“Ga On Jai(嘉稳斋)”曾是“博览城”之一。新主人购买了该地的老房子后,将它拆除,... 详细信息

纪念性场地大约20年前,韩国政府在江南举办了“房博会”,建造了这座低层住宅的“世博小镇”,小镇的每一处建筑都是由当时韩国著名的建筑师精心设计的。“Ga On Jai(嘉稳斋)”曾是“博览城”之一。新主人购买了该地的老房子后,将它拆除,重新建造了新房子。客户要求-最大程度上利用土地空间,赋予生态化“最大程度上利用土地空间,赋予生态化”是房主的重点要求,因为他认为被拆毁的老房子的外部空间狭窄、无用且内部空间呈蓝黑色。

关键词：低层住宅外部空间土地空间生态化老房子内部空间博览城纪念性场地

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