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Prenatal and postnatal factors associated with sudden infant death syndrome:an umbrella review of meta-analyses

World Journal of Pediatrics 2024年第5期20卷 451-460页

作者： Tae Hyeon kim Hyeri Lee Selin Woo Hayeon Lee Jaeyu Park Guillaume Fond Laurent Boyer Jong Woo Hahn Jiseung Kang Dong Keon Yon Department of Medicine Kyung Hee University College of MedicineSeoulSouth Korea Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea Department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea Department of Biomedical Engineering Kyung Hee UniversityYonginSouth Korea CEReSS-Health Service Research and Quality of Life Center Assistance Publique des Hôpitaux de MarseilleAix-Marseille UniversityMarseilleFrance Department of Pediatrics Seoul National University College of MedicineSeoulSouth Korea Department of Pediatrics Seoul National University Bundang HospitalSeongnamSouth Korea Department of Anesthesia Critical Care and Pain MedicineMassachusetts General Hospital14913th StreetRoom 4140CharlestownBostonMAUSA Division of Sleep Medicine Harvard Medical SchoolBostonMAUSA Department of Pediatrics Kyung Hee University Medical CenterKyung Hee University College of Medicine23 Kyungheedae-roDongdaemun-guSeoul02447South Korea Department of Precision Medicine Kyung Hee University College of MedicineSeoulSouth Korea

Background Comprehensive quantitative evidence on the risk and protective factors for sudden infant death syndrome(SIDS)effects is *** investigated the risk and protective factors related to *** We conducted an umbrella review of meta-analyses of observational and interventional studies assessing SIDS-related ***/MEDLINE,Embase,EBSCO,and Google Scholar were searched from inception until January 18,*** extraction,quality assessment,and certainty of evidence were assessed by using A Measurement Tool Assessment Systematic Reviews 2 following PRISMA *** to observational evidence,credibility was graded and classified by class and quality of evidence(CE;convincing,highly suggestive,suggestive,weak,or not significant).Our study protocol was registered with PROSPERO(CRD42023458696).The risk and protective factors related to SIDS are presented as equivalent odds ratios(eORs).Results We identified eight original meta-analyses,including 152 original articles,covering 12 unique risk and protective factors for SIDS across 21 countries/regions and five *** risk factors,including prenatal drug exposure[eOR=7.84(95%CI=4.81–12.79),CE=highly suggestive],prenatal opioid exposure[9.55(95%CI=4.87–18.72),CE=suggestive],prenatal methadone exposure[9.52(95%CI=3.34–27.10),CE=weak],prenatal cocaine exposure[4.38(95%CI=1.95–9.86),CE=weak],prenatal maternal smoking[2.25(95%CI=1.95–2.60),CE=highly suggestive],postnatal maternal smoking[1.97(95%CI=1.75–2.22),CE=weak],bed sharing[2.89(95%CI=1.81–4.60),CE=weak],and infants found with heads covered by bedclothes after last sleep[11.01(95%CI=5.40–22.45),CE=suggestive],were *** the other hand,three protective factors,namely,breastfeeding[0.57(95%CI=0.39–0.83),CE=non-significant],supine sleeping position[0.48(95%CI=0.37–0.63),CE=suggestive],and pacifier use[0.44(95%CI=0.30–0.65),CE=weak],were also *** Based on the evidence,we propose several risk and protecti

关键词： Infant Protective factor Risk factor Sudden infant death syndrome Umbrella review

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Extraction and Purification of Depigmenting Agents from Chinese Plants

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Chemical Research in Chinese Universities 2006年第2期22卷 162-167页

作者： AHN So-young ROW kyung-ho kim Eun-ki School of Chemical and Biological Engineering Center for Advanced Bioseparation Technology Inha University Nam-Ku Incheon 402-751 Korea

Depigmenting agents were solvent-extracted and purified by preparative and analytical HPLC from three Chinese plants; Chrysanthemum morifolium Ramat（ Xizang Caijuhua）, Rhodiola sachalinensis, and Terminalia chebula Retzius. Four fractions obtained from the ethyl ether layer of C. m. Rama and two fractions from the ethyl acetate layer of Rhodiola salientness show depigmenting effects. At 8 200, the ethyl acetate layers of Chrysanthemum morifolium Ramat, Rhodiola sachalinensis and the methanol extract of Terminalia chebula Retzius, can inhibit the melanin production of mouse B16 melanoma cells by 92%, 60% and 90%, respectively, whereas 46% inhibition was observed by commercially available depigmenting agents（arbutin）. These results show the potential of these three Chinese plants as a novel resource for depigmenting agents in the cosmetic industry.

关键词： Chrysanthemum Morifolium Ramat Rhodiola Sachalinensis Terminalia Chebula Retzius Melanin Inhibitory Effect HPLC

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Optimization of post-warranty sequential inspection for second-hand products

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Journal of Systems Engineering and Electronics 2017年第4期28卷 793-800页

作者： Dae-kyung kim Jae-Hak Lim Dong Ho Park Department of Statistics Chonbuk National University Department of Management & Accounting Hanbat National University Industry Academic Cooperation Foundation Hallym University

This paper considers an optimal sequential inspection schedule for a second-hand product after that the free nonrenewable warranty is expired. The length of warranty is prespecified and during the warranty period, the product is minimally repaired by the dealer when it fails. Following the expiration of the non-renewing warranty, the product is inspected and upgraded sequentially a fixed number of times at the expenses of the *** each inspection, the failure rate of the product is reduced proportionally so that the product is upgraded. The product is assumed to deteriorate as it ages and the replacement of the product occurs when a fixed number of inspections are rendered. In addition,the intervals between two successive inspections are assumed to decrease monotonically. The main objective of this paper is to determine the optimal improvement level to upgrade the product at each inspection so that the expected maintenance cost during the life cycle of the product is minimized from the perspective of the customer. Under the given cost structures, we derive an explicit formula to obtain the expected maintenance cost incurred during the life cycle of the product and discuss the method to find the optimal level of the improvement analytically in case the failure times follow the Weibull distribution. Numerical results are analyzed to observe the impact of relevant parameters on the optimal solution.

关键词： second-hand product sequential inspection upgrade action life cycle of the product expected maintenance cost free non-renewable warranty

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TinyML-Based Classification in an ECG Monitoring Embedded System

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Computers, Materials & Continua 2023年第4期75卷 1751-1764页

作者： Eunchan kim Jaehyuk kim Juyoung Park Haneul Ko Yeunwoong kyung Department of Intelligence and Information Seoul National UniversitySeoul08826Korea Nexon Korea Cop. SeongnamKyungki13487Korea Advanced CP Lab.Samsung Electronics SuwonKyungki16677Korea Department of Electronic Engineering Kyung Hee UniversityYonginKyungki17104Korea Division of Information&Communication Engineering Kongju National UniversityCheonanChungcheongnam31080Korea

Recently, the development of the Internet of Things (IoT) hasenabled continuous and personal electrocardiogram (ECG) monitoring. In theECG monitoring system, classification plays an important role because it canselect useful data (i.e., reduce the size of the dataset) and identify abnormaldata that can be used to detect the clinical diagnosis and guide furthertreatment. Since the classification requires computing capability, the ECGdata are usually delivered to the gateway or the server where the classificationis performed based on its computing resource. However, real-time ECG datatransmission continuously consumes battery and network resources, whichare expensive and limited. To mitigate this problem, this paper proposes atiny machine learning (TinyML)-based classification (i.e., TinyCES), wherethe ECG monitoring device performs the classification by itself based onthe machine-learning model, which can reduce the memory and the networkresource usages for the classification. To demonstrate the feasibility, afterwe configure the convolutional neural networks (CNN)-based model usingECG data from the Massachusetts Institute of Technology (MIT)-Beth IsraelHospital (BIH) arrhythmia and the Physikalisch Technische Bundesanstalt(PTB) diagnostic ECG databases, TinyCES is validated using the TinyMLsupportedArduino prototype. The performance results show that TinyCEScan have an approximately 97% detection ratio, which means that it has greatpotential to be a lightweight and resource-efficient ECG monitoring system.

关键词： Holter ECG arduino internet of things(IoT) TinyML

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Miniaturized Twin-legged Robot with an Electromagnetic Oscillatory Actuator

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Journal of Bionic Engineering 2018年第1期15卷 106-113页

作者： Buhyun Shin Youngshik kim Jamie Paik kyung-min Lee Department of Mechanical Engineering Hanbat National University 125 Dongseodaero Yuseong-gu Daejeon 34158 Republic of Korea The Institute of Mechanical Engineering EPFL BM 4118 Station 17 1015-Lausanne Switzerland School of Mechanical Engineering Yeungnam University 280 Daehak-Ro Gyeongsan Gyeongbuk 38541 Republic of Korea

There have been many studies on the moving mechanism of micro robots, such as stick-slip, inchworm like motion, and impact drive. Novel actuators like lead zirconate titanate （PZT）, Shape Memory Alloy （SMA）, magnetostrictive materials, electromagnetic actuators, electoractive polymers, ultrasonic linear motors, and dielectric elastomers are utilized to realize the moving mechanism. The use of a conventional electromagnetic actuator is unfavorable, because of a few drawbacks, such as generation of stray magnetic fields, hard to miniaturize to the millimeter scale because of 3D integration and a scaling law, and power consumption to maintain a certain position. This research presents a micro robot that uses an electromagnetic actuator customized and developed for micro robot. The electromagnetic actuator is designed from a Brushless Direct Current （BLDC） motor to overcome the drawbacks mentioned above. The developed robot is composed of two electromagnetic actuators. The overall size of the robot is 20 mm × 11 mm× 9 mm （length × height × width） and the weight is 3 g. The developed robot is able to move bidirectionally with a maximum moving speed of 15.76 mm·s︿-1 （0.79 body-length per second）. The optimal conditions of an input signal are calculated theoretically and verified with experiments.

关键词： electromagnetic actuator oscillatory actuator bionic micro robot stick-slip brushless DC motor

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How to deliver palliative care for patients with management in decompensated cirrhosis

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Hepatobiliary Surgery and Nutrition 2023年第4期12卷 576-579页

作者： Beom kyung kim Department of Internal medicine Yonsei University College of MedicineSeoulRepublic of Korea Institute of Gastroenterology Yonsei University College of MedicineSeoulRepublic of Korea Yonsei Liver Center Severance HospitalSeoulRepublic of Korea

Palliative care is defined as multidisciplinary,specialized medical care that meets the needs of patients with serious illnesses and their caregivers from the standpoints of the physical,spiritual,and emotional levels(1).Nowadays,it is also considered to be one of the fundamental care programs for patients with decompensated cirrhosis,as has also been demonstrated in the field of other cancers(2).Recently,the guidance regarding“palliative care and symptom-based management in decompensated cirrhosis”had been published in 2022 by the American Association for the Study of Liver Diseases(AASLD)(3).

关键词： Palliative care decompensation cirrhosis

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A GIS-Based Framework for Real-Time Debris-Flow Hazard Assessment for Expressways in Korea

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International Journal of Disaster Risk Science 2016年第3期7卷 293-311页

作者： Han-Saem kim Choong-Ki Chung Sang-Rae kim kyung-Suk kim Earthquake Research Center Korea Institute of Geoscience and Mineral Resources Department of Civil and Environmental Engineering Seoul National University Department of Civil and Environmental Engineering Northwestern University Expressway and Transportation Research Institute Korea Expressway Corporation

Debris flows caused by heavy rainfall in mountain areas near expressways lead to severe social and economic losses and sometimes result in ***, the development of a real-time system for debris-flow hazard assessment is necessary to provide preliminary information for rapid decision making about evacuations or restoration measures, as well as to prevent secondary disasters caused by debris flows. Recently,various map-based approaches have been proposed using multi-attribute criteria and assessment methods for debrisflow susceptibilities. For the macrozonation of debris-flow hazard at a national scale, a simplified method such as the Korea Expressway Corporation(KEC) debris-flow hazard assessment method can be applied for systematic analysis based on geographic information systems(GIS) and monitoring networks. In this study, a GIS-based framework of real-time debris-flow hazard assessment for expressway sections is proposed based on the KEC debris-flow hazard assessment method. First, the KEC-based method was standardized in a systematic fashion using Arc GIS,enabling the objective and quantitative acquisition of various attribute datasets. The quantification of rainfall criteria also was considered. A safety management system for debris-flow hazard was developed based on the GIS platform. Finally, the method was applied and verified on three expressway sections in Korea. The grading standard for each individual influencing attribute was subsequently modified to more accurately assess the debris-flow hazards.

关键词： Debris-flow hazard Expressway management GIS Korea Real-time hazard assessment

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K2Ti6O13 Nanoparticle-Loaded Porous rGO Crumples for Supercapacitors

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Nano-Micro Letters 2020年第1期12卷 115-123页

作者： Chongmin Lee Sun kyung kim Hankwon Chang Hee Dong Jang Department of Nanomaterials Science and Engineering University of Science and TechnologyYuseong‑guDaejeon 34113Republic of Korea Resources Utilization Research Center Korea Institute of Geoscience and Mineral ResourcesYuseong‑guDaejeon 34132Republic of Korea

One-dimensional alkali metal titanates containing potassium,sodium,and lithium are of great concern owing to their high ion mobility and high specific surface *** those titanates are combined with conductive materials such as graphene,carbon nanotube,and carbon nanofiber,they are able to be employed as efficient electrode materials for *** hexa-titanate(K2Ti6O13,KTO),in particular,has shown superior electrochemical properties compared to other alkali metal titanates because of their large lattice parameters induced by the large radius of potassium ***,we present porous rGO crumples(PGC)decorated with KTO nanoparticles(NPs)for application to *** KTO NP/PGC composites were synthesized by aerosol spray pyrolysis and post-heat *** NPs less than 10 nm in diameter were loaded onto PGCs ranging from 3 to 5μ*** porous structure of the composites was obtained by the activation of rGO by adding an excessive amount of KOH to the *** KTO NP/PGC composite electrodes fabricated at the GO/KOH/TiO2 ratio of 1:3:0.25 showed the highest performance(275 F g−1)in capacitance with different KOH concentrations and cycling stability(83%)after 2000 cycles at a current density of 1 A g−1.

关键词： Potassium hexa-titanate Porous graphene crumples Supercapacitors

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Single-atom Pd catalyst anchored on Zr-based metal-organic polyhedra for Suzuki-Miyaura cross coupling reactions in aqueous media

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Nano Research 2021年第2期14卷 486-492页

作者： Seongsoo kim Seohyeon Jee kyung Min Choi Dong-Sik Shin Division of Chemical and Bioengineering Kangwon National UniversityGangwon-do 24341Republic of Korea Department of Chemical and Biological Engineering Sookmyung Womens University100 Cheongpa-ro 47-gilYongsan-guSeoul 04310Republic of Korea

The challenge for single-atom catalysts in various C-C cross coupling reaction exists in the development of solid supporting *** has been desired tofind a supporting material designed in molecular level to anchor a single-atom catalyst and provide high degree of dispersion and substrate access in aqueous ***,we prepared discrete cages of metal-organic polyhedra anchoring single Pd atom(MOP-BPY(Pd))and successfully performed a Suzuki-Miyaura cross coupling reaction with various substrates in aqueous *** was revealed that each tetrahedral cage of MOP-BPY(Pd)has 4.5 Pd atoms on average and retained its high degree of dispersion up to 3 months in *** coupling efficiencies of the Suzuki-Miyaura cross coupling reaction exhibited more than 90.0%for various substrates we have tested in the aqueous media,which is superior to those of the molecular Pd complex and metal-organic framework(MOF)anchoring Pd ***,MOP-BPY(Pd)was successfully recovered and recycled without performance degradation.

关键词： metal-organic polyhedra Suzuki-Miyaura cross coupling reaction structure characterization aqueous phase reaction high-degree of dispersion

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Aging Behavior of Mg-Y-Zr and Mg-Nd-Zr Cast Alloys

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Journal of Materials Science & Technology 2008年第1期24卷 80-84页

作者： Yang-Do kim Nam-Hyun Kang Il-Guk Jo kyung-Hyun kim In-Bae kim School of Materials Science and Engineering Pusan National University 30 Jangjun-dongGeumjeong-guBusan 609-735Korea Deptartment of Materials Engineering Korea Institute of Machinery & Materials 66 Sangnam-dongChangwonGyeongsangnam-do 641-010Korea

Aging behavior of Mg-3.6Y-0.5Zr and ***-0.5Zr alloys was investigated by microhardness measurement and transmission electron *** the case of Mg-Y-Zr alloy,the presence ofβ″phase,a major strength- ener,having base centered orthorhombic structure with its lattice constants of a-（β″）=0.64 nm,b-（β″）=2.22 nm, and c-（β″）=0.52 nm was *** the case of Mg-Nd-Zr alloy aged at 250℃,the presence ofβ″andβ′phases was *** crystal structure ofβ″phase was found to be DO-（19） and its orientation relationships with Mg matrix were [0001]-（β″）//[0001]-（Mg） and [01（？）0]-（β″）//[01（？）0]-（Mg）.Theβ′phase had face centered cubic structure and its orientation relationships with Mg matrix were [011]-（β′）//[0001]-（Mg） and [（？）1（？）]β′//[（？）110]）-（Mg）. The ***-0.5Zr alloy showed higher hardness compared with Mg-3.6Y-0.5Zr alloy.

关键词： Mg-Y-Zr alloy Mg-Nd-Zr alloy Precipitation sequence

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