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Asian Pacific Journal of Tropical Medicine 2016年第10期9卷 980-984页

作者： So Jung kim So Yun Park Sun-Mee Hong Eun-Hye Kwon Taek-kyun Lee Gyeongbuk Institute for Marine Bio-Industry South Sea Environment Research Department Korea Institute of Ocean Science and Technology

Objective: To determine skin whitening and wrinkle improvement efficacy, glycoprotein fractions were extracted from liquid extracts of boiled sea cucumber and their effects on tyrosine and elastase inhibitory activities were assayed. Methods: Fractions above and below 50 k Da(>50 kD a and 50 kDa enhanced tyrosinase and elastase inhibitory activities by 50.84% and 28.78%, respectively. Correlations of the >50 kD a concentration with tyrosinase inhibitory(R^2=0.968) and elastase inhibitory(R2=0.983) efficacy were significant. Conclusions: >50 kD a glycoprotein fraction isolated from liquid extracts of boiled sea cucumber, which can serve as a functional cosmetic ingredient for whitening and wrinkle improvement of skin.

关键词： Sea cucumber Glycoprotein Cytotoxicity Tyrosinase Elastase

Characteristics of Algal Succession Following Rock Scraping at Imwon Area in the East Coast of Korea

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Journal of Ocean University of China 2016年第6期15卷 1087-1093页

作者： Young Dae kim Jung Kwan Alan Myung Mo Nam Chu Lee Hyun Il Yoo Su Yeoung Yeon Young Hwan kim Jang kyun kim Jae Suk Choi East Sea Fisheries Research Institute National Fisheries Research & Development Institute Gangneung 210-860Republic of Korea Korea National Park Service National Park Research Institute Yeosu 550-833 Republic of Korea Seaweed Research Center 1rational Fisheries Research & Development lnstituie Mokpo 530-831 Republic of Korea Department of Biology Chungbuk National University Chongju 361-763 Republic Of Korea Department of Marine Science School of Natural Sciences Incheon National University 22012 Yeonsu-gu Incheon Korea Department of Marine Sciences University of Connecticut 06901 Stamford Connecticut USA Division of Bioindustry Silla University Sasang-gu Busan 617-736 Republic of Korea

This study was conducted to clarify the characteristics of algal succession following rock scraping using hoe or high-pressure water sprayer in the period from June 2010 to April 2011. We divided the research area off the eastern coast of Korean near Imwon into 3 categories depending upon the severity of the barren ground, i.e., the urchin barren-affected, urchin barren-ongoing and urchin barren-free areas. In April 2011, in the urchin barren-affected area with 25 seaweed species, the cover percentage and importance value(IV) of crustose coralline algae were higher than those of other species. In the urchin barren-ongoing area with 33 seaweed species, crustose coralline algae(mean IV = 62%) as well as Sargassum sp.(mean IV = 28%), and Gelidium amansii(mean IV = 19%) were observed following rock scraping. In the urchin barren-free area where seaweed communities were relatively abundant with 42 species, a variety of algal species including G. amansii(mean IV = 32%) underwent algal succession. Overall, it was observed that, as an aspect of algal succession, the weaker the barren ground severity was, the more frequent and diverse the seaweeds were, and the more complex the succession pattern was in the study. As an aspect of recovering algal community, rock scraping using hoe was shown to be superior to the method using high-pressure water spraying. Therefore, we conclude that rock scraping using hoe is a very effective strategy for recovering the algal community in urchin barren-ongoing area.

关键词：藻类群落东海岸岩石演替韩国严重程度水喷雾珊瑚藻

Modified rendezvous intrahepatic bile duct cannulation technique to pass a PTBD catheter in ERCP

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World Journal of Gastroenterology 2010年第42期16卷 5388-5390页

作者： Tae Hoon Lee Sang-Heum Park Sae Hwan Lee Chang-kyun Lee Suck-Ho Lee Il-Kwun Chung Hong Soo kim Sun-Joo kim Division of Gastroenterology Department of Internal MedicineSoon Chun Hyang University College of MedicineCheonan Hospital23-20 Bongmyung-dongCheonan-siChungcheongnam-do330-721South Korea

The rendezvous procedure combines an endoscopic technique with percutaneous transhepatic biliary drainage(PTBD).When a selective common bile duct cannulation fails,PTBD allows successful drainage and retrograde access for subsequent rendezvous ***,rendezvous procedures such as the PTBDassisted over-the-wire cannulation method,or the parallel cannulation technique,may be available when a bile duct cannot be selectively *** selective intrahepatic bile duct(IHD) cannulation fails,this modified rendezvous technique may be a feasible *** report the case of a modified rendezvous technique,in which the guidewire was retrogradely passed into the IHD through the C2 catheter after end-to-end contact between the tips of the sphincterotome and the C2 catheter at the ampulla's orifice,in a 39-year-old man who had been diagnosed with gallbladder carcinoma with a metastatic right IHD *** this procedure may be a feasible and timesaving technique.

关键词： Endoscopic retrograde cholangiopancreatography Intrahepatic bile duct Rendezvous technique

In-situ formation of MOF derived mesoporous Co3N/amorphous N-doped carbon nanocubes as an efficient electrocatalytic oxygen evolution reaction

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Nano Research 2019年第7期12卷 1605-1611页

作者： Bong kyun Kang Seo Young Im Jooyoung Lee Sung Hoon Kwag Seok Bin Kwon SintayehuNibret Tiruneh Min-Jun kim Jung Ho kim Woo Seok Yang Byungkwon Lim Dae Ho Yoon Nano Materials and Components Research Center Korea Electronics Technology InstituteSeongnam 463-816Republic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan University Suwon 440-746Republic of Korea Advanced Materials & Processing Center Institute for Advanced Engineering (IAE)Yongin 175-28Republic of Korea Australian Institute for Innovative Materials (AIIM) University of WollongongSquires WayNorth Wollongong NSW 2500Australia Department of Advanced Materials Engineering for Information and Electronics Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do17104Republic of Korea

The suitable materials,metal nitrides,are a promising class of electrocatalyst materials for a highly efficient oxygen evolution reaction (OER) because they exhibit superior intrinsic conductivity and have higher sustainability than oxide-based *** our knowledge,for the first time,we report a designable synthesis of three-dimensional (3D) and mesoporous Co3N@ amorphous N-doped carbon (AN-C) nanocubes (NCs) with well-controlled open-framework structures via monodispersed Co3[Co(CN)6]2 Prussian blue analogue (PBA) NC precursors using in situ nitridation and calcination ***3N@AN-C NCs (2 h) demonstrate better OER activity with a remarkably low Tafel plot (69.6 mV-dec-1),low overpotential of 280 mV at a current density of 10 ***,excellent cycling stability in alkaline electrolytes was exhibited without morphological changes and voltage elevations,superior to most reported hierarchical structures of transition-metal nitride *** presented strategy for synergy effects of metal-organic frameworks (MOFs)-derived transition-metal nitrides-carbon hybrid nanostructures provides prospects for developing high-performance and advanced electrocatalyst materials.

关键词： transition-metal nitride metal organic framework mesoporous oxygen evaluation reaction alkaline water electrolysis

Adult intussusception caused by colonic anisakis: A case report

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World Journal of Clinical Cases 2019年第17期7卷 2536-2541页

作者： Youn I Choi Dong kyun Park Hyun Yee Cho Seung Joon Choi Jun-Won Chung kyung Oh kim Kwang An Kwon Yoon Jae kim Department of Gastroenterology Gachon UniversityGil Medical CenterIncheon 21565South Korea Department of Pathology Gachon University Gil Medical CenterIncheon 21565South Korea

BACKGROUND Colo-colonic intussusception is an uncommon phenomenon in an *** intussusception accounts for < 5% of total cases,and the colo-colonic type is < 30% of *** surgical management has been the treatment of choice for intestinal intussusception in adults,because most frequent causes for adult intussusception are malignant in origin,the importance of the roles of preoperative colonoscopic evaluation has recently been *** SUMMARY We report an extremely rare case of adult colo-colonic intussusception caused by colonic anisakiasis and successfully treated by endoscopic removal of the Anisakis body.A 59-year-old man visited the emergency department due to 1 day of lower abdominal colicky *** computed tomography (APCT) revealed the presence of mid-transverse colon intussusception without definite necrosis,which was possibly related with colorectal *** there was no evidence of necrosis at the intussusception site,a colonoscopy was performed to target the colonic lesion and obtain tissue for a histopathological *** Anisakis body was found when inspecting the suspicious colonic lesion recorded by *** Anisakis body was removed with forceps assisted by *** patient’s symptoms improved dramatically after removing the Anisakis.A reduced colon without any pathological findings was seen on the follow-up *** any further treatment,the patient was discharged 5 d after the *** When colonic intussusception without necrosis occurs in an adult,physician should consider a colonoscopy to exclude causes cured by endoscopy.

关键词： Intussusception Anisakis Colonoscopy Case report

Metabolic syndrome is associated with erosive esophagitis

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World Journal of Gastroenterology 2008年第35期14卷 5442-5447页

作者： Jung Ho Park Dong IL Park Hong Joo kim Yong kyun Cho Chong IL Sohn Woo kyu Jeon Byung Ik kim Department of Medicine Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoulSouth Korea

AIM: To clarify whether insulin resistance and metabolic syndrome are risk factors for erosive esophagitis. METHODS: A case-control study was performed using the database of the Kangbuk Samsung Hospital Medical Screening Center. RESULTS: A total of 1679 cases of erosive esophagitis and 3358 randomly selected controls were included. Metabolic syndrome was diagnosed in 21% of the cases and 12% of the controls (P < 0.001). Multiple logistic regressions confirmed the association between erosive esophagitis and metabolic syndrome (Odds ratio, 1.25; 95% CI, 1.04-1.49). Among the components of metabolic syndrome, increased waist circumference, elevated serum triglyceride levels and hypertension were significant risk factors for erosive esophagitis (all P < 0.01). Furthermore, increased insulin resistance (Odds ratio, 0.91; 95% CI, 0.85-0.98) and fatty liver, as diagnosed by ultrasonography (Odds ratio, 1.39; 95% CI, 1.20-1.60), were also related to erosive esophagitis even after adjustment for a series of confounding factors. CONCLUSION: Metabolic syndrome and increased insulin resistance are associated with an increased risk of developing erosive esophagitis.

关键词：新陈代谢综合症侵蚀性食道炎胰岛素抵抗脂肪肝

Fatty acid methyl ester profiles and nutritive values of 20 marine microalgae in Korea

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Asian Pacific Journal of Tropical Medicine 2015年第3期8卷 191-196页

作者： Sung-Suk Suh So Jung kim Jinik Hwang Mirye Park Taek-kyun Lee Eui-Joon Kil Sukchan Lee South Sea Environment Research Department Korea Institute of Ocean Science and Technology Kyeongbuk Institute for Marine Bio-Industry Department of Genetic Engineering Sungkyunkwan University

Objecive:To screen the fatty acid(FA) composition of 20 marine microalgae species,including seven Diophyceae,six Bacillariophyeae four Chlorophyceae,two Haptophyceae and one Raphidophyceae ***:Microalgal cells cultured at the Korea Institute of Ocean Science & Technology were harvested during the late exponential growth phase and the FA composition ***:The FA composition of microalgae was *** example,seven different species of Dinophyceae were composed primarily of C14:0,C16:0.C18:0.C20:4n-6.C20:5n-3 and C22:*** C14:0.C16:0,C16:1.C18:0.C20:5n-3 and C22:6n-3 were abundant FAs in six species of *** addition,four Chlurophyceae,two Haptopkyeeae and one Raphidophyceae species all contained a high degree of C16:1 n-7[(9.2R-34.91)%and(34.48-35.04)%].C14:0[(13.34-25.96)%]and[(26.69-Z8.24)%],and C16:0[(5.89-29.15)%]and[(5.70-16.81)%].Several factors contribute to the nutritional value of *** the polyunsaturated FA content and n-3 to n-6 FA ratio,which could be used to assess the nutritional quality of ***:This study is the first comprehensive assessment of the FA composition and nutritional value of microalgae species in South Korea,and identifies the potential utility of FAs as species-specific biomarkers.

关键词： Microalgae PUFA Nutritive values DHA EPA

Carbon and nitrogen dynamics in a Pinus densiflora forest with low and high stand densities

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Journal of Plant Ecology 2013年第5期6卷 368-379页

作者： Nam Jin Noh Choonsig kim Sang Won Bae Woo kyun Lee Tae kyung Yoon Hiroyuki Muraoka Yowhan Son Division of Environmental Science and Ecological Engineering Korea UniversitySeoul 136-713Republic of Korea River Basin Research Center Gifu UniversityGifu 501-1193Japan Department of Forest Resources Gyeongnam National University of Science and TechnologyJinju 660-758Republic of Korea Department of Forest Conservation Korea Forest Research InstituteSeoul 130-712Republic of Korea

Aims Understanding carbon(C)and nitrogen(N)dynamics and their dependence on the stand density of an even-aged,mature forest provides knowledge that is important for forest *** study investigated the differences in ecosystem total C and N storage and flux between a low-density stand(LD)and a high-density stand(HD)and examined the effects of stand density on aboveground net primary productivity(ANPP),total belowground C allocation(TBCA)and net ecosystem production(NEP)in a naturally regenerated,65-to 75-year-old Pinus densiflora *** *** LD(450 trees ha^(−1))and HD(842 trees ha^(−1))were established in an even-aged,mature *** forest in September *** forest had been naturally regenerated following harvesting,and the stand density was naturally maintained without any artificial management such as *** diameter at breast height(DBH≥5.0cm)of all live stems within the stands was measured yearly from 2007 to *** compare C and N storage and fluxes in LD and HD,C and N pools in aboveground and belowground biomass,the forest floor,coarse woody debris(CWD)and soil;soil CO_(2) efflux(R_(S));autotrophic respiration(R_(A));litter production;and soil N availability were ***,ANPP,TBCA and NEP were estimated from plot-based measurement *** Findings Ecosystem C(Mg C ha^(−1))and N(Mg N ha^(−1))storage was,respectively,173.0±7.3(mean±SE)and 4.69±0.30 for LD and 162±11.8 and 4.08±0.18 for *** were no significant differences in C and N storage in the ecosystem components,except for soils,between the two *** contrast,there were significant differences in aboveground ANPP and TBCA between the two stands(P<0.05).Litterfall,biomass increment and R_(S) were major C flux components with values of,respectively,3.89,3.74 and 9.07 Mg C ha^(−1) year^(−1) in LD and 3.15,2.94 and 7.06 Mg C ha^(−1) year^(−1) in ***-based NEP(Mg C ha^(−1) year^(−1))was 4.18 in LD and 5.50 in *** the even-aged,mature P

关键词： aboveground net primary productivity net ecosystem production Japanese red pine stand density total belowground carbon allocation

Detection of coat protein gene of nervous necrosis virus using loopmediated isothermal amplification

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Asian Pacific Journal of Tropical Medicine 2016年第3期9卷 230-235页

作者： Jinik Hwang Sung-Suk Suh Mirye Park Myung-Joo Oh Jong-Oh kim Sukchan Lee Taek-kyun Lee South Sea Environment Research Department Korea Institute of ocean science & technology Korea University of Science and Technology Department of Aqualife Medicine Chonnam National University Department of Genetic Engineering Sungkyunkwan University

Objective:To establish a novel and highly specific loop-mediated isothermal amplification(LAMP) assay for the identification of nervous necrosis virus(NNV) ***:A set of synthesized primers was used to match the sequences of a specific region of the nnr gene from the National Center for Biotechnology Information database,not originating from NNV-infected fish,the efficiency and specificity of LAMP were measured dependent on the concentration of DNA polymerase and the reaction temperature and *** addition,to determine species-specific LAMP primers,cross reactivity testing was applied to the reaction between NVV and other virus families including viral hemorrhagic septicemia virus and marine ***:The optimized LAMP reaction carried out at 64 ℃ for 60 min,and above 4 U Bst DNA *** sensitivity of LAMP for the detection of nnv was thus about 10 times greater than the sensitivity of polymerase chain *** LAMP assay primers were specific for the detection NNV infection in Epinephelus ***:The development of LAMP primers based on genetic information from a public database,not virus-infected samples,may provide a very simple and convenient method to identify viral infection in aquatic organisms.

关键词： Nervous necrosis virus Nodaviridae Polymerase chain reaction Loop-mediated isothermal Amplification

Outcome of laparoscopic cholecystectomy is not influenced by chronological age in the elderly

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World Journal of Gastroenterology 2009年第6期15卷 722-726页

作者： Hyung Ook kim Jung Won Yun Jun Ho Shin Sang Il Hwang Yong kyun Cho Byung Ho Son Chang Hak Yoo Yong Lai Park Hungdai kim Departments of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of MedicineSeoul 110-746 South Korea Departments of Internal Medicine Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoul 110-746South Korea

AIM:To evaluate the outcome of laparoscopic cholecystectomy(LC)in patients aged 80 years and older. METHODS:A total of 353 patients aged 65 to 79 years(group 1)and 35 patients aged 80 years and older(group 2)underwent *** were further classified into two other groups:those with uncomplicated gallbladder disease(group A)or those with complicated gallbladder disease(group B). RESULTS:There were no significant differences between the age groups(groups 1 and 2)with respect to clinical characteristics such as age,gender,comorbid disease,or disease *** operative time,conversion rate,and the incidence of major postoperative complications were similar in groups 1 and ***,the percentage of high-risk patients was significantly higher in group 2 than in group 1 (20.0%vs 5.7%,P<0.01).Group A comprised 322 patients with a mean age of 71.0±5.3 years,and group B comprised 51 patients with a mean age of 69.9±4.8 *** group B,mean operative time (78.4±49.3 min vs 58.3±35.8 min,P<0.01),mean postoperative hospital stay(7.9±6.5 d vs 5.0±3.7 d, P<0.01),and the incidence of major postoperative complications(9.8%vs 3.1%,P<0.05)were significantly greater than in group *** conversion rate tended to be higher in group B,but this difference was not significant. CONCLUSION:Perioperative outcomes in elderly patients who underwent LC seem to be influenced by the severity of gallbladder disease,and not by chronologic *** octogenarians,LC should be performed at an earlier,uncomplicated stage of the disease whenever possible to improve perioperative outcomes.

关键词：胆囊切除术老年人胆囊炎治疗方法