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Prevalence of premature ejaculation in young and middle-aged men in Korea： a multicenter intemet-based survey from the Korean Andrological Society

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Asian Journal of Andrology 2010年第6期12卷 880-889页

作者： Hyun Jun Park Jong Kwan Park Kwangsung Park Sung Won Lee Sae-Woong Kim Dae Yul Yang DU Geon Moon kweon-sik min Ki-Hak Moon Sang-Kuk Yang Jae Seog Hyun Nam Cheol Park Deparment of Urology Pusan National University School of medicine Busan 602739 Korea Deparment of Urology Chonbuk National University Medical School Jeonju 561712 Korea Deparment of Urology Chonnam National University Medical School Gwangju 501746 Korea Deparment of Urology Sungkyunkwan Univer＆ty School of Medicine Seou1135 710 Korea Deparment of Urology Catholic University College of Medicine Seoul 137701 Korea Deparment of Urology Hallym University College of Medicine Seoul 13 7701 Korea Deparment of Urology Korea University College of Medicine Seoul 152703 Korea Deparment of Urology lnje University College of Medicine Busan 614735 Korea Deparment of Urology Yeungnam University College of Medicine Daegu 705717 Korea Deparment of Urology Konkuk University School of Medicine Chungju 380704 Korea Deparment of Urology Gyeongsang National University School of Medicine Jinju 660702 Korea

In this study, we aimed to investigate the prevalence and perception of premature ejaculation （PE） in young and middle-aged Korean men. The study was conducted using an Internet-assisted questionnaire. A total of 2 037 Korean male adults, aged 20 years or older, were randomly sampled based on age and residency. The questionnaire developed by the PE Study Group of the Korean Andrological Society includes four categories （overall sexual function, symptoms, distress and treatment） with a total of 16 questions. For each question, symptoms were evaluated by a scale ranging from 0 to 10. Intravaginal ejaculation latency time was ‘5-10 min＇ in 38.6%, followed by ‘longer than 10 min＇ in 2919%, ‘2-5 min＇ in 23.6%, ‘1-2 min＇ in 5.4% and ‘shorter than 1 min＇ in 2.5%. In our series, 27.5% of respondents reported having PE. Control over ejaculation within a recent 3-month period was 6.2 points on average. Respondent complaints of PE-related stress averaged 7.1 points and stress-related complaints from sexual partners averaged 7.1 points. The effect of PE on sexual life was 6.8 points. Of the respondents determined as having PE, 42.6% responded that they were inclined to receive treatment. Results from this study suggest that the prevalence of PE diagnosed by the respondent on his own was approximately 27.5% in young and middle-aged men in Korea. PE-related stress had a significant effect on the stress, sexual activity and quality of life of the respondent and his sexual partner.

关键词： epidemiology premature ejaculation questionnaire sexual dysfunction

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Long-term outcome of stem cell transplantation with and without anti-tumor necrotic factor therapy in perianal fistula with Crohn’s disease

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World Journal of Stem Cells 2024年第3期16卷 257-266页

作者： min Young Park Yong sik Yoon Jae Ha Park Jong Lyul Lee Chang sik Yu Division of Colon and Rectal Surgery Department of SurgeryYonsei University College of MedicineSeoul 03722South Korea Division of Colon and Rectal Surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea

BACKGROUND Stem cell transplantation is a promising therapeutic option for curing perianal fistula in Crohn’s disease(CD).Anti-tumor necrotic factor(TNF)therapy combined with drainage procedure is effective as ***,previous studies are limited to proving whether the combination treatment of biologics and stem cell transplantation improves the effect of fistula *** This study aimed to evaluate the long-term outcomes of stem cell transplantation and compare Crohn’s perianal fistula(CPF)closure rates after stem cell transplantation with and without anti-TNF therapy,and to identify the factors affecting CPF closure and *** The patients with CD who underwent stem cell transplantation for treating perianal fistula in our institution between Jun 2014 and December 2022 were *** data were compared according to anti-TNF therapy and CPF *** A total of 65 patients were *** median age of females was 26 years(range:21-31)and that of males was 29(44.6%).The mean follow-up duration was 65.88±32.65 months,and complete closure was observed in 50(76.9%)*** closure rates were similar after stem cell transplantation with and without anti-TNF therapy(66.7%vs 81.6%at 3 year,P=0.098).The patients with fistula closure had short fistulous tract and infrequent proctitis and anorectal stricture(P=0.027,0.002,and 0.008,respectively).Clinical factors such as complexity,number of fistulas,presence of concurrent abscess,and medication were not significant for *** cumulative 1-,2-,and 3-year closure rates were 66.2%,73.8%,and 75.4%,*** Anti-TNF therapy does not increase CPF closure rates in patients with stem cell ***,both refractory and non-refractory CPF have similar closure rates after additional anti-TNF *** tract length,proctitis,and anal stricture are risk factors for non-closure in patients with CPF after stem cell transplantation.

关键词： Crohn’s disease Anus Fistula Stem cell transplantation Tumor necrosis factor-alpha inhibitors Infliximab

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Driving inward growth of lithium metal in hollow microcapsule hosts by heteroatom‐controlled nucleation

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Carbon Energy 2024年第8期6卷 262-272页

作者： Siwon Kim Hong Rim Shin Ki Jae Kim min‐sik Park Jong‐Won Lee Division of Materials Science and Engineering Hanyang UniversitySeoulRepublic of Korea Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Energy Science Sungkyunkwan UniversitySuwonRepublic of Korea Department of Advanced Materials Engineering for Information and Electronics Integrated Education for Frontier Science and Technology(BK21 Four)Kyung Hee UniversityYonginRepublic of Korea

The application of Li metal anodes in rechargeable batteries is impeded by safety issues arising from the severe volume changes and formation of dendritic Li ***‐dimensional hollow carbon is receiving increasing attention as a host material capable of accommodating Li metal inside its cavity;however,uncontrollable and nonuniform deposition of Li remains a *** this study,we synthesize metal–organic framework‐derived carbon microcapsules with heteroatom clusters(Zn and Ag)on the capsule walls and it is demonstrated that Ag‐assisted nucleation of Li metal alters the outward‐to‐inward growth in the microcapsule ***‐incorporated microcapsules are prepared via chemical etching of zeolitic imidazole framework‐8 polyhedra and are subsequently decorated with Ag by a galvanic displacement reaction between Ag^(+)and metallic *** introduced Ag significantly reduces the energy barrier and increases the reaction rate for Li nucleation in the microcapsule host upon Li *** combined electrochemical,microstructural,and computational studies,we verify the beneficial role of Ag‐assisted Li nucleation in facilitating inward growth inside the cavity of the microcapsule host and,in turn,enhancing electrochemical *** study provides new insights into the design of reversible host materials for practical Li metal batteries.

关键词： hollow carbon hosts lithium metal batteries lithium plating metal-organic frameworks nucleation

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Treatment preferences in men with erectile dysfunction： an open label study in Korean men switching from sildenafil citrate to tadalafil

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Asian Journal of Andrology 2007年第6期9卷 760-770页

作者： Tai Young Ahn Sung Won Lee Sae-Woong Kim Dae Yul Yang Nam Cheol Park kweon-sik min Kwangsung Park Jae-Seung Paick Yulia Dyachkova Trisha Dwight Myung-Sea Luke Lee Asan Medical Centre Seoul 138-736 Korea Samsung Medical Centre Seoul 135-710 Korea Youido St Marys Hospital Seoul 150-713 Korea Kang Dong Sacred Heart Hospital Seoul 134-701 Korea Pusan National University Hospital Pusan 602-739 Korea Pusan lnje University Paik Hospital Pusan 614-735 Korea Chonnam National University Hospital Gwangju 501-757 Korea Seoul National University Hospital Seoul 110-744 Korea Area Medical Centre Vienna Eli Lilly Austria Sydney A-1030 Australia Intercontinental Information Sciences Eli Lilly Australia Sydney 2113 Australia Eli Lilly Korea Seoul 135-280 Korea

To evaluate patient preferences for sildenafil citrate or tadalafil （PDE-5 inhibitors available for the treatment of erectile dysfunction [ED]） and assess potential reasons for these preferences. Methods： This open-label study was conducted on Korean men taking sildenafil, at least 6 weeks prior to study entry, for ED. Following screening, patients continued sildenafil treatment for 4 weeks, then after a 1-week washout period, switched to tadalafil for 8 weeks. Patients then continued with their treatment of choice during an extension phase. Psychosocial factors （time concern, spontaneity, sexual self-confidence） were evaluated using Psychological and Interpersonal Relation- ship Scales （PAIRS）, while timing of dose to sexual attempt patterns were assessed from patient diaries. Results： The present study enrolled 160 Korean men （mean age 55 years） with prior median sildenafil use of 585 days. During the extension phase, 73.7% of patients elected to take tadalafil, whereas 26.3% chose sildenafil （P 〈 0.001）. After switching from sildenafil to tadalafil, mean PAIRS time concern scores decreased from 2.54 to 2.42 （P = 0.002）, with no statistically significant differences observed between the sildenafil and tadalafil assessment phases in sexual spontaneity and self-confidence scores. Sexual attempts made 〉 4 h to 〈 36 h post-dose occurred in 4.5% of patients during the sildenafil assessment phase compared with 17.5% during the tadalafil assessment phase. Conclusion： After experiencing both sildenafil and tadalafil, the majority of patients exhibited a preference for tadalafil. This preference might be influenced by psychosocial factors, such as decreased time concerns, and a broader window of opportunity available for sexual activity.

关键词： erectile dysfunction tadalafil sildenafil citrate Psychological and Interpersonal Relationship Scales preference

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Short- and long-term outcomes of surgical treatment in patients with intestinal Behcet’s disease

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 429-437页

BACKGROUND Behcet’s disease(BD),a chronic vasculitic disorder affecting multiple organs,is characterized by recurrent oral and genital ulcers,arthritis,vasculitis,and intes-tinal *** intestinal involvement of BD is common in East Asia,the efficacy and long-term outcomes of surgical treatment of intestinal BD still remain to be *** To evaluate the postoperative clinical course of intestinal BD and determine factors associated with its *** Data from patients who underwent surgical treatment for intestinal BD between January 2010 and August 2021 were retrospectively ***’demo-graphics,clinical features,postoperative course,complications,and follow-up data were *** We analyzed 39 surgeries in 31 *** mean patient age was 45.1 years,and the mean interval between the diagnosis of intestinal BD and surgical treatment was 4.9 years(range 1.0-8.0 years).The most common indication for surgery was medical intractability(n=16,41.0%),followed by fistula or abscess(n=11,28.2%).Laparoscopic approaches were used in 19 patients(48.7%),and 5 patients(12.8%)underwent emergency *** most common surgical procedure was ileocecal resection(n=18,46.2%),followed by right colectomy(n=11,28.2%).A diverting stoma was created in only one patient(2.6%).During a mean follow-up period of 45(range 8-72)months,eight cases(20.5%)of recurrence in five patients required *** interval between operations was 12.1 months(range 6.3-17.8 mo).Four patients(10.3%)experienced recurrence within 1 year postoperatively,and all eight recurrences occurred within 2 years of the initial *** reoperation rates at 1 and 3 years were 10.3%and 20.5%,respectively.A redo ileocolic anastomosis was performed in all recurrent *** multivariate Cox regression analysis,emergency surgery[hazard ratio(HR)9.357,95%confidence interval(CI):1.608-54.453,P=0.013]and elevated C-reactive protein(CRP)levels(HR 1.154,95%CI:1.002–1.328,

关键词： Behcet syndrome Intestinal General surgery Recurrence Risk factors

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New anti-mesenteric delta-shaped stapled anastomosis: Technical report with short-term postoperative outcomes in patients with Crohn’s disease

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2592-2601页

作者： Jong Lyul Lee Yong sik Yoon Hyun Gu Lee Young Il Kim min Hyun Kim Chan Wook Kim In Ja Park Seok-Byung Lim Chang sik Yu Division of Colon and Rectal Surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of Surgery Gangdong Kyung Hee University HospitalSeoul 05278South Korea

BACKGROUND Medical treatment for Crohn’s disease(CD)has continuously improved,which has led to a decrease in surgical recurrence *** these advancements,25%of patients will undergo repeat intestinal *** of CD com-monly occurs on the mesentery side of the anastomosis *** To compare the new anti-mesenteric side-to-side delta-shaped stapled anasto-mosis(DSA)with the conventional stapled functional end-to-end anastomosis(CSA).METHODS This retrospective study included CD patients who underwent ileo-ileal or ileo-colic anastomosis between January 2020 and December *** DSA technique employed a stapler to maintain the concept of anti-mesentery side-to-side ana-stomosis by performing a 90°vertical closure of the open window compared with the CSA *** the corner where the open window is closed,the DSA avoids forming a pouch and creates an anastomosis resembling a delta shape within the intestinal *** compared demographics,preoperative condition,operative findings,and operative outcomes for the two *** The study included 175 patients,including 92 in the DSA group and 83 in the CSA *** two groups were similar in baseline characteristics,preoperative medical treatment,and operative findings except for the Montreal classification *** 30-days postoperative complication rate was signi-ficantly lower in the DSA group compared with the CSA group(16.3%vs 32.5%,P=0.009).Ileus incidence was significantly lower in the DSA group than in the CSA group(4.3%vs 14.5%,P=0.033),and the hospital stay was shorter in the DSA group than in the CSA group(5.67±1.53 days vs 7.39±3.68 days,P=0.001).CONCLUSION The DSA technique was feasible and showed comparable postoperative outcomes with lower short-term complic-ations compared with the CSA *** studies on CD recurrence and long-term complications are warranted.

关键词： Crohn’s disease Surgery Anastomosis Complication Recurrence

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Realizing High Thermoelectric Performance in n-Type Se-Free Bi2Te3 Materials by Spontaneous Incorporation of FeTe2 Nanoinclusions

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Energy & Environmental Materials 2024年第4期7卷 344-354页

作者： Jamil Ur Rahman Woo Hyun Nam Yong-Jae Jung Jong Ho Won Jong-min Oh Nguyen Van Du Gul Rahman Víctor M.García-Suárez Ran He Kornelius Nielsch Jung Young Cho Won-Seon Seo Jong Wook Roh Sang-il Kim Soonil Lee Kyu Hyoung Lee Hyun sik Kim Weon Ho Shin Leibniz Institute for Solid State and Materials Research Advanced Materials Convergence R&D Division Korea Institute of Ceramic Engineering & Technology Department of Electronic Materials Engineering Kwangwoon University Department of Energy Engineering Dankook University Faculty of Fundamental Science Phenikaa University Department of Physics Quaid-i-Azam University Departamento de Física Universidad de Oviedo Nanomaterials and Nanotechnology Research Center-CINN Department of Materials Science and Engineering Yonsei University School of Nano & Materials Science and Engineering Kyungpook National University Department of Materials Science and Engineering University of Seoul School of Materials Science and Engineering Changwon National University

Bi2Te3-based materials have drawn much attention from the thermoelectric community due to their excellent thermoelectric performance near room ***,the stability of existing n-type Bi2（Te,Se）3materials is still low due to the evaporation energy of Se (37.70 kJ mol-1) being much lower than that of Te (52.55 kJ mol-1).The evaporated Se from the material causes problems in interconnects of the module while degrading the efficiency.

关键词： Bi2Te3 energy harvesting FeTe2 nanoinclusion n-type materials thermoelectric

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Effectiveness of sensory integration therapy in children,focusing on Korean children:A systematic review and meta-analysis

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World Journal of Clinical Cases 2024年第7期12卷 1260-1271页

作者： Seri Oh Jong-sik Jang A-Ra Jeon Geonwoo Kim Mihwa Kwon Bahoe Cho Narae Lee Department of Occupational Therapy Kangwon National University Graduate SchoolSamcheok 25949South Korea Department of Occupational Therapy Kangwon National UniversitySamcheok 25949South Korea Department of Occupational Therapy Ju-Ju Children Development CenterNonsansi 32985Chungcheongnam-doSouth Korea Department of Occupation Therapy Suwon Women’s UniversityGyeonggi-do 16632South Korea Hijam Center for Development of Children Ochang 28117South Korea Department of Occupational Therapy U1 UniversityChung-cheong bukdo 25949South Korea

BACKGROUND Sensory integration intervention is highly related to the child's effective interaction with the environment and the child's ***,various sensory integration interventions are being applied,but research methodological problems are arising due to unsystematic *** study aims to present the optimal intervention protocol by presenting scientific standards for sensory integration intervention through *** To prove the effectiveness of sensory integration therapy,examine the latest trend of sensory integration studies in Korea,and provide clinical evidence for sensory integration *** The database of Korean search engines,including RISS,KISS,and DBpia,was used to search for related literature published from 2001 to October *** keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this ***,a meta-analysis was conducted on 24 selected studiesRISS,KISS,and DBpia,was used to search for related literature published from 2001 to October *** keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this ***,a meta-analysis was conducted on 24 selected *** Sensory integration intervention has been proven effective in children with cerebral palsy,autism spectrum disorder,attention deficit/hyperactivity disorder,developmental disorder,and intellectual disability in relation to the diagnosis of *** sensory integration therapies,1:1 individual treatment with a therapist or a therapy session lasting for 40 min was most *** terms of dependent variables,sensory integration therapy effectively promoted social skills,adaptive behavior,sensory processing,and gross motor and fine motor *** The results of this study may be used as therapeutic evidence for sensory integration intervention in the clinical field of occupational therapy for

关键词： Children Meta-analysis Occupational therapy Sensory integration Sensory processing Social skills

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Speech enhancement through voice activity detection using speech absence probability based on Teager energy

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Journal of Central South University 2013年第2期20卷 424-432页

作者： PARKYun-sik LEE Sang-min Department of Electronic Engineering Inha University Institute for Information and Electronics Research Inha University

In this work, a novel voice activity detection （VAD） algorithm that uses speech absence probability （SAP） based on Teager energy （TE） was proposed for speech enhancement. The proposed method employs local SAP （LSAP） based on the TE of noisy speech as a feature parameter for voice activity detection （VAD） in each frequency subband, rather than conventional LSAP. Results show that the TE operator can enhance the abiTity to discriminate speech and noise and further suppress noise components. Therefore, TE-based LSAP provides a better representation of LSAP, resulting in improved VAD for estimating noise power in a speech enhancement algorithm. In addition, the presented method utilizes TE-based global SAP （GSAP） derived in each frame as the weighting parameter for modifying the adopted TE operator and improving its performance. The proposed algorithm was evaluated by objective and subjective quality tests under various environments, and was shown to produce better results than the conventional method.

关键词： speech enhancement Teager energy speech absence probability voice activity detection

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Improvement of hydrogen embrittlement and stress corrosion cracking by annealing for Al-4.4Mg-0.6Mn alloy

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 17-22页

作者： Seong-Jong KIM min-Su HAN Seong-kweon KIM Seok-Ki JANG Division of Marine Engineering Mokpo National Maritime University Media Engineering Seoul National University of Technology

With no annealing treatment, cathodic polarization trends in 5083F A1 alloy revealed concentration polarization and activation polarization. However, the annealed specimens have lower current densities at corrosion protection potential compared to the non-annealed specimen. The results of SSRTs conducted in seawater at the applied potential range of-l.8 V to -0.5 V indicated that the maximum tensile strength, elongation, and time-to-fracture had high values at applied potentials of -0.7 to -1.4 V. The maximum tensile strength, elongation, and time-to-f？acture decreased when the potential values were beyond this range in either anodic or cathodic direction. In general, the increased shear lip caused by annealing treatment indicates elongation. Time-to-fracture would likely increase with elongation. Potentials between -0.5 V to -0.6 V were found to be in the region of stress corrosion cracking. The corrosion protection zone was determined to be -0.7 V to -J,4 V because these potential ranges produced good mechanical properties. Potential less than -1.4 V produced a fractured surface with a mixture of dimples （ductile fractures） and a quasi-cleavage pattern resulting from the effects of hydrogen gas.

关键词： annealing 5083F A1-Mg alloy corrosion seawater slow strain rate tests

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