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Clinicopathological features of small T1 colorectal cancers

World Journal of Clinical Cases 2021年第33期9卷 10088-10097页

作者： Yuki Takashina Shin-Ei Kudo Katsuro Ichimasa Yuta Kouyama Kenichi Mochizuki Yoshika Akimoto Yasuharu Maeda Yuichi Mori Masashi Misawa Noriyuki Ogata Toyoki Kudo Tomokazu Hisayuki Takemasa Hayashi kunihiko wakamura Naruhiko Sawada Toshiyuki Baba Fumio Ishida Kazunori Yokoyama Mitsuru Daita Tetsuo Nemoto Hideyuki Miyachi Digestive Disease Center Showa University Northern Yokohama HospitalYokohama 224-8503Japan Department of Gastroenterology Nikko Kinen HospitalMuroran 051-8501Japan Clinical Effectiveness Research Group Institute of Health and SocietyUniversity of OsloOslo 0001Norway Department of Pathology Showa University Nothern Yokohama HospitalYokohama 224-8503Japan

BACKGROUND Although small colorectal neoplasms(<10 mm)are often easily resected endoscopically and are considered to have less malignant potential compared with large neoplasms(≥10 mm),some are invasive to the *** To clarify the clinicopathological features of small T1 colorectal *** Of 32025 colorectal lesions between April 2001 and March 2018,a total of 1152 T1 colorectal cancers resected endoscopically or surgically were included in this study and were divided into two groups by tumor size:a small group(<10 mm)and a large group(≥10 mm).We compared clinicopathological factors including lymph node metastasis(LNM)between the two *** The incidence of small T1 cancers was 10.1%(116/1152).The percentage of initial endoscopic treatment in small group was significantly higher than in large group(<10 mm 74.1%vs≥10 mm 60.2%,P<0.01).In the surgical resection cohort(n=798),the rate of LNM did not significantly differ between the two groups(small 12.3%vs large 10.9%,P=0.70).In addition,there were also no significant differences between the two groups in pathological factors such as histological grade,vascular invasion,or lymphatic *** Because there was no significant difference in the rate of LNM between small and large T1 colorectal cancers,the requirement for additional surgical resection should be determined according to pathological findings,regardless of tumor size.

关键词： Colorectal neoplasms Lymphatic metastasis Biological phenomena Polyps Colorectal cancers

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Endocytoscopic narrow-band imaging efficiency for evaluation of inflammatory activity in ulcerative colitis

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World Journal of Gastroenterology 2015年第7期21卷 2108-2115页

作者： Yasuharu Maeda Kazuo Ohtsuka Shin-ei Kudo kunihiko wakamura Yuichi Mori Noriyuki Ogata Yoshiki Wada Masashi Misawa Akihiro Yamauchi Seiko Hayashi Toyoki Kudo Takemasa Hayashi Hideyuki Miyachi Fuyuhiko Yamamura Fumio Ishida Haruhiro Inoue Shigeharu Hamatani Digestive Disease Center Showa University Northern Yokohama Hospital Department of Gastroenterology and Hepatology Tokyo Medical and Dental University Hospital Endoscopy Center Showa Hospital Department of Pathology Showa University Northern Yokohama Hospital

AIM:To assess the efficacy of endocytoscopic narrowband imaging(EC-NBI)for evaluating the severity of inflammation in ulcerative colitis(UC).METHODS:This retrospective study was conducted at a single tertiary care referral *** included UC patients who underwent colonoscopy with endocytoscopy from July 2010 to December *** was performed,and the images were evaluated by assessing visibility,increased vascularization,and the increased calibers of capillaries and were classified as Obscure,Visible or *** was indicative of inactive disease,while Visible and Dilated were indicative of acute *** study received Institutional Review Board *** primary outcome measures included the diagnostic ability of EC-NBI to distinguish between active and inactive UC on the basis of histological *** conventional endoscopic images were classified according to the Mayo endoscopic score.A score of 0 or 1 indicated inactive disease,whereas a score of 2 indicated active ***:Fifty-two patients were *** was a strong correlation between the EC-NBI findings and the histological assessment(r=0.871,P<0.01).The sensitivity,specificity,positive predictive value,negative predictive value,and accuracy of EC-NBI for diagnosing acute inflammation were 84.0%,100%,87.1%,100%,and 92.3%,respectively,while those for the Mayo endoscopic score were 100%,40.7%,100%,61.0%,and 69.2%,*** with conventional endoscopy,EC-NBI was superior in diagnostic specificity,negative predictive value,and accuracy(P<0.001,P=0.001 and P=0.047,respectively).CONCLUSION:The EC-NBI finding of capillaries in the rectal mucosa was strongly correlated with histological inflammation and aided in the differential diagnosis between active and inactive UC.

关键词： Endosytoscopy Narrow-band imaging Magnified endosc

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SPIN DEPENDENT DIELECTRIC PARAMETERS IN FERRIMAGNETIC SEMICONDUCTOR CoCr2S4

SPIN DEPENDENT DIELECTRIC PARAMETERS IN FERRIMAGNETIC SEMICO...

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The 2nd International Symposium on Physics of Magnetic Materials

作者： Kunio wakamura Kazuhiro Kita Graduate School of Applied Science Okayama University of Science1-1 Ridai-choOkayama 700Japan

We have measured far-infrared reflectivity spectra from 18 K to 290 K for spinel type ferrimagnetic *** rapid decrease of optical(ε) and static(ε) dielectric constants have been observed near and below *** shifts forεandε are analyzed by remarking the spin dependent electronic energy state and by the spin dependent effective charge together withεvalue,respectively. From these results,the importance of optical phonon and electronic energy state near the band gap in the magnetoelectric effect will be pointed out.

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合成昆虫性信息素用于害虫防治的进展

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农药译丛 1993年第4期15卷 2-6页

作者： Sadao wakamura 周红晞日本国立蚕业和昆虫科学研究所

虽然合成有机农药已在农业生产中起重要作用,但也带来诸如食用作物残留、害虫机体农药抗性发展等消极影响。在这样的情况下,远比常规化学杀虫剂更安全更富选择性的合成性信息素无疑是一种有希望可供选择的手段。 1971年,日本已验明小卷... 详细信息

虽然合成有机农药已在农业生产中起重要作用,但也带来诸如食用作物残留、害虫机体农药抗性发展等消极影响。在这样的情况下,远比常规化学杀虫剂更安全更富选择性的合成性信息素无疑是一种有希望可供选择的手段。 1971年,日本已验明小卷叶蛾类和桔黄小卷叶蛾同属昆虫性信息素成份。此后,随着微量化学技术令人瞩目的进展,现已验明50多种害虫信息素的化学成份,并广泛用于昆虫行为研究和田间试验,试验结果表明应用昆虫合成性信息素是可行的。

关键词：卷叶蛾合成昆虫性信息素防治

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Effects of UV Irradiation on the Locomotor Activity and Body Temperature Rhythms in Hairless Mice

Effects of UV Irradiation on the Locomotor Activity and Body...

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The 3rd Asian and Oceanian Conference on Photobiology

作者： Eri Chikamori Tomoko Sudo Atsuko Masuda Kanako Muramatsu Morihiro Yoneda Tomoko wakamura Hiromi Tokura Tadashi Oishi Faculty of Science Faculty of Science Faculty of Science KYOUSEI Science Center for Life and Nature Faculty of Human Life and Environment Nara Women’s UniversityNara 630-8506Japan Faculty of Medicine Kyoto UniversityKyoto 606-8501Japan Institute of Textiles ＆ Clothing The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Faculty of Science Nara Saho College Rokuyaon-cho 806Nara 630-8566Japan

＜正＞Effects of ultra violet light （UV） irradiation on the skin physiology have been studied well. However, other effects than the skin physiology have not been investigated so much. On the other hand, visible light is reported to be most important as a zeitgeber to entrain circadian rhythms in animals. However, effects of UV on the circadian rhythms such as locomotor activity and body temperature rhythms have not been investigated well. Therefore, in this study, we examined the effects of UV irradiation on the circadian rhythms of locomotor activity and body temperature in hairless mice.

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