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Chinese Journal of Aeronautics 2020年第9期33卷 2372-2381页

作者： Binbin GENG Yanfei ZUO Zhinong JIANG kun feng Chen WANG Jie WANG Key Lab of Engine Health Monitoring-Conlrol and Netw orking of Ministry of Education Beijing University of Chemical TechnologyBeijing 100029China Beijing Key Laboratory of High-end Mechanical Equipment Health Monitoring and Self-Recovery Beijing University of Chemical TechnologyBeijing 100029China

Bearings in a gas turbine engine are the key connecting components transmitting force and motion between rotors and thin-walled flexible *** bearing stiffness and damping of squeeze film damper(SFD)nearby bearings are easily affected by many factors,such as assembly process,load condition and temperature variation,resulting in *** uncertainties may influence the response of the measuring point on the ***,it is difficult to carry out the fault diagnosis,whole machine balancing and other related *** this paper,a double integral quantitative evaluation method is proposed to simultaneously analyze the influence of two uncertain dynamic coefficients on the response amplitude and phase of casing measuring ***,the coupling influence of stiffness and damping accompanied by dramatic changes with rotational speeds are essentially *** an example,a typical engine bearing-casing system with complex dynamic characteristics is *** impact of uncertain dynamic coefficients on the unbalance response is quantitatively evaluated.

关键词： Dynamic coefficients Gas turbine engine Measuring point response Quantitative evaluation Uncertainty analysis

Research on the method of construction disturbance zoning for shield tunnel approaching to urban structures

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FRONTIERS OF STRUCTURAL AND CIVIL ENGINEERING 2024年第11期18卷 1663-1679页

作者： Zhou, Ziyang Guo, Fukang Ni, Jianzhong feng, kun Zhang, Jingxuan Liu, Yiwen Southwest Jiaotong Univ Key Lab Transportat Tunnel Engn Minist Educ Chengdu 610031 Peoples R China Hangzhou Fuyang City Construct Investment Grp Co L Hangzhou 310000 Peoples R China

This paper presents a calculation method that evaluates the extent of disturbance based on structural safety limits. Additionally, it summarizes the assessment methods for construction disturbance zones in shield tunneling near pile foundations, urban ground structures, and underground structures. Furthermore, taking the construction of the Chengdu Jinxiu Tunnel under bridges and urban pipelines as the engineering background, a study on the disturbance zoning of adjacent structures was conducted. The most intense disturbance occurs within one week of the tunnel underpass process, and it has a significant impact within a range of two times the tunnel diameter along the tunnel axis. The bridge pile and bridge deck experience less disturbance from tunnel approaching construction, with a maximum disturbance zone characterized as medium disturbance. On the other hand, underground pipelines are subjected to more significant disturbances from tunnel construction, with a maximum disturbance zone classified as strong disturbance. The implementation of "bridge pile sleeve valve pipe grouting & underground pipeline ground grouting & tunnel advance grouting" in the field effectively limits the vertical settlement of bridges and pipelines, resulting in a decrease of approximately 0.1 in disturbance level for the structures. The disturbance zoning method can assess tunnel disturbance with structures, identify high-risk interference locations, and facilitate targeted design reinforcement solutions.

关键词： shield tunnel approaching construction field monitoring disturbance zoning method

Novel Quasi Solid-State Succinonitrile-based Electrolyte with Low-flammability for Lithium-ion Battery

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Chinese Journal of Polymer Science 2023年第11期41卷 1695-1705,I0005页

作者： Yan-kun Xie Lu-kun feng Dong-Dong Li Yin Tang Cai-Zhen Zhu Ming-Liang Wang Jian Xu Institute of Low-Dimensional Materials Genome Initiative College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen 518060China

Quasi solid-state succinonitrile(SN)-based polymer electrolytes have emerged for lithium-metal batteries due to their excellent ionconductivity at room temperature,wide electrochemical stability window(ESW,usually>5 V).However,the practical application of these solid SN-based polymer electrolytes is hampered by the flammability and the inherent instability of SN to Li-metal *** this work,solid SN-based polymer electrolytes were prepared with succinonitrile,ethoxylated trimethylolpropane triacrylate(ETPTA),triethyl phosphate(TEP)and fluoroethylene carbonate for Li-metal battery via in situ polymerization *** SN-based polymer electrolytes with 5 wt%triethyl phosphate and FEC showed good nonflammability,superior ion-conductivity as high as 1.01×10^(-3)S/cm,and wide ESW of 5.41 *** SN-based polymer electrolyte also exhibited excellent interfacial compatibility to lithium metal *** it also delivered a high specific capacity of 156m Ah/g at 0.2 C at ambient temperature,and presented stable cycling at 1.0 C with a specific capacity retention of 98.4%after 1000 *** work provides an alternative and simple strategy to realize the practical application of the solid-state SN-based polymer electrolyte.

关键词： Solid polymer electrolyte Succinonitrile Solid-state battery In situ polymerization Low-flammability

The effects of caudal fin deformation on the hydrodynamics of thunniform swimming under self-propulsion

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Journal of Hydrodynamics 2020年第6期32卷 1122-1137页

作者： Yi-kun feng Yu-min Su Huan-xing Liu Yuan-yuan Su College of Shipbuilding Engineering Harbin Engineering UniversityHarbin150001China Beijing Institute of Specialized Machinery Beijing100081China Science College Harbin Engineering UniversityHarbin150001China

To investigate the effects of the caudal fin deformation on the hydrodynamic performance of the self-propelled thunniform swimming,we perform fluid-body interaction simulations for a tuna-like swimmer with thunniform *** 3-D vortices are visualized to reveal the role of the leading-edge vortex(LEV)in the thrust *** comparing the swimming velocity of the swimmer with different caudal fin flexure amplitudes fa,it is shown that the acceleration in the starting stage of the swimmer increases with the increase of fa,but its cruising velocity *** results indicate that the caudal fin deformation is beneficial to the fast start but not to the fast cruising of the *** the entire swimming process,the undulation amplitudes of the lateral velocity and the yawing angular velocity decrease as fa *** is found that the formation of an attached LEV on the caudal fin is responsible for generating the low-pressure region on the surface of the caudal fin,which contributes to the ***,the caudal fin deformation can delay the LEV shedding from the caudal fin,extending the duration of the low pressure on the caudal fin,which will cause the caudal fin to generate a drag-type force over a time period in one swimming cycle and reduce the cruising speed of the swimmer.

关键词： Computational fluid dynamics(CFD)numerical simulation self-propulsion caudal fin deformation

PHLDA2 reshapes the immune microenvironment and induces drug resistance in hepatocellular carcinoma

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Oncology Research 2024年第6期32卷 1063-1078页

作者： kun feng HAO PENG QINGPENG LV YEWEI ZHANG Hepatopancreatobiliary Center The Second Affiliated Hospital of Nanjing Medical UniversityNanjing210000China Medical School Southeast UniversityNanjing210000China

Hepatocellular carcinoma(HCC)is a malignancy known for its unfavorable *** dysregulation of the tumor microenvironment(TME)can affect the sensitivity to immunotherapy or chemotherapy,leading to treatment *** elucidation of PHLDA2’s involvement in HCC is imperative,and the clinical value of PHLDA2 is also ***,bioinformatics analysis was performed in multiple cohorts to explore the phenotype and mechanism through which PHLDA2 may affect the progression of ***,the expression and function of PHLDA2 were examined via the qRT-PCR,Western Blot,and MTT *** findings indicate a substantial upregulation of PHLDA2 in HCC,correlated with a poorer *** methylation levels of PHLDA2 were found to be lower in HCC tissues compared to normal liver ***,noteworthy associations were observed between PHLDA2 expression and immune infiltration in *** addition,PHLDA2 upregulation is closely associated with stemness features and immunotherapy or chemotherapy resistance in *** vitro experiments showed that sorafenib or cisplatin significantly up-regulated PHLDA2 mRNA levels,and PHLDA2 knockdown markedly decreased the sensitivity of HCC cells to chemotherapy ***,we found that TGF-βinduced the expression of PHLDA2 in *** GSEA and in vitro experiment indicated that PHLDA2 may promote the HCC progression via activating the AKT signaling *** study revealed the novel role of PHLDA2 as an independent prognostic factor,which plays an essential role in TME remodeling and treatment resistance in HCC.

关键词： HCC Immune infiltration Drug resistance TME PHLDA2

Production Cross-Section Estimates for Strongly-Interacting Electroweak-Symmetry Breaking Sector Resonances at Particle Colliders

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Communications in Theoretical Physics 2015年第12期64卷 701-709页

作者： Antonio Dobado GUO feng-kun Felipe J.Llanes-Estrada Departamento de Física Teórica Universidad Complutense de Madrid State Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of Science Helmholtz-Institut für Strahlen-und Kernphysik and Bethe Center for Theoretical Physics Universitat Bonn

We are exploring a generic strongly-interacting Electroweak Symmetry Breaking Sector(EWSBS) with the low-energy effective field theory for the four experimentally known particles(W_L~±,Z_l,h) and its dispersion-relation based unitary *** this contribution we provide simple estimates for the production cross-section of pairs of the EWSBS bosons and their resonances at proton-proton colliders as well as in a future e^-e^+(or potentially aμ^-μ^+) collider with a typical few-TeV *** examine the simplest production mechanisms,tree-level production through a W(dominant when quantum numbers allow) and the simple effective boson approximation(in which the electroweak bosons are considered as collinear partons of the colliding fermions).We exemplify with custodial isovector and isotensor resonances at 2 TeV,the energy currently being discussed because of a slight excess in the ATLAS 2-jet *** find it hard,though not unthinkable,to ascribe this excess to one of these W_lW_l rescattering *** isovector resonance could be produced at a rate smaller than,but close to earlier CMS exclusion bounds,depending on the parameters of the effective *** ZZ excess is then problematic and requires additional physics(such as an additional scalar resonance).The isotensor one(that would describe all charge combinations) has smaller cross-section.

关键词： strongly interacting electroweak symmetry breaking

Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3429-3448页

作者： Hao Peng Meng Yang kun feng Qingpeng Lv Yewei Zhang Medical School Southeast UniversityNanjing 210009China Department of Ultrasound State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of MedicalSciencesPeking Union Medical CollegeBeijing 100730China Hepatopancreatobiliary Center The Second Affiliated Hospital of Nanjing Medical UniversityNanjing 210009China

More than 90% of hepatocellular carcinoma(HCC)cases develop in the presence of fibrosis or cirrhosis,making the tumor microenvironment(TME)of HCC distinctive due to the intricate interplay between cancer-associated fibroblasts(CAFs)and cancer stem cells(CSCs),which collectively regulate HCC ***,the mechanisms through which CSCs orchestrate the dynamics of the tumor stroma during HCC development remain *** study unveils a significant upregulation of Sema3C in fibrotic liver,HCC tissues,peripheral blood of HCC patients,as well as sorafenib-resistant tissues and cells,with its overexpression correlating with the acquisition of stemness properties in *** further identify NRP1 and ITGB1 as pivotal functional receptors of Sema3C,activating downstream AKT/Gli1/c-Myc signaling pathways to bolster HCC self-renewal and tumor ***,HCCcells-derived Sema3Cfacilitated extracellular matrix(ECM)contraction and collagen deposition in vivo,while also promoting the proliferation and activation of hepatic stellate cells(HSCs).Mechanistically,Sema3C interacted with NRP1 and ITGB1 in HSCs,activating downstream NF-kB signaling,thereby stimulating the release of IL-6 and upregulating HMGCR expression,consequently enhancing cholesterol synthesis in ***,CAF-secreted TGF-β1 activates AP1 signaling to augment Sema3C expression in HCC cells,establishing a positive feedback loop that accelerates HCC ***,blockade of Sema3C effectively inhibits tumor growth and sensitizes HCC cells to sorafenib in *** sum,our findings spotlight Sema3C as a novel biomarker facilitating the crosstalk between CsCs and stroma during hepatocarcinogenesis,thereby offering a promising avenue for enhancing treatment efficacy and overcoming drug resistance in HCC.

关键词： Sema hepatocellular thereby

Microphone Array Speech Separation Algorithm Based on TC-ResNet

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Computers, Materials & Continua 2021年第11期69卷 2705-2716页

作者： Lin Zhou Yue Xu Tianyi Wang kun feng Jingang Shi School of Information Science and Engineering Southeast UniversityNanjing210096China Center for Machine Vision and Signal Analysis University of OuluOuluFI-90014Finland

Traditional separation methods have limited ability to handle the speech separation problem in high reverberant and low signal-to-noise ratio(SNR)environments,and thus achieve unsatisfactory *** this study,a convolutional neural network with temporal convolution and residual network(TC-ResNet)is proposed to realize speech separation in a complex acoustic environment.A simplified steered-response power phase transform,denoted as GSRP-PHAT,is employed to reduce the computational *** extracted features are reshaped to a special tensor as the system inputs and implements temporal convolution,which not only enlarges the receptive field of the convolution layer but also significantly reduces the network computational *** blocks are used to combine multiresolution features and accelerate the training procedure.A modified ideal ratio mask is applied as the training *** results demonstrate that the proposed microphone array speech separation algorithm based on TC-ResNet achieves a better performance in terms of distortion ratio,source-to-interference ratio,and short-time objective intelligibility in low SNR and high reverberant environments,particularly in untrained *** indicates that the proposed method has generalization to untrained conditions.

关键词： Residual networks temporal convolution neural networks speech separation

Production of Charged Heavy Quarkonium-Like States at the LHC and Tevatron

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Communications in Theoretical Physics 2014年第3期61卷 354-358页

作者： GUO feng-kun Ulf-G. MeiBner WANG Wei Helmholtz-Institut fiir Strahlen- und Kernphysik and Bethe Center for Theoretical Physics Universitat Bonn D-53115 Bonn Germany Institute for Advanced Simulation Institut fiir Kernphysik and Jiilich Center for Hadron Physics JARA-FAME and JARA-HPC Forschungszentrum Jfilich D-52425 Jfilich Germany

We study prompt hadroproduction of the charged bottomonium-like states Zb± （10610） and Zb±（10650）, and the charged eharmonium-like states Zc± （3900） and Zc± （4020）, at the Tevatron and the LHC, provided that these states are S-wave hadronic molecules. Using two Monte Carlo event generators, Herwig and Pythia, to simulate the production of heavy meson pairs, we derive an order-of-magnitude estimate of the production rates for these four particles. Our estimates yield a cross section at the nb level for the Zb（10610） and Zb（10650）. The results for the Zc（3900） and Zc （4020） are larger by a factor of 2~30. These cross sections are large enough to be observed, and measurements at hadron colliders in the future will supplement the study using electron-positron collisions, and therefore allow to explore the mysterious nature of these exotic states.

关键词： exotic hadrons hadroproduction

Electrocatalysis induced reconstruction of RuNiPO for highly efficient hydrogen evolution reaction

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Journal of Energy Chemistry 2023年第12期87卷 24-31,I0003页

作者： Junhui Hu Bai Xu Jiabin Xu Shuo Li Zhonghu Liu Cheng Lu Yong feng kun feng Jun Zhong Institute of Functional Nano and Soft Materials Laboratory(FUNSOM) Jiangsu Key Laboratory of Advanced Negative Carbon TechnologiesSoochow UniversitySuzhou 215123JiangsuChina Department of Chemistry University of Western OntarioLondonOntario N6A 5B7Canada

Reconstruction during the catalytic process has been considered to play a key role for the *** we report a RuNiPO based catalyst for efficient alkaline hydrogen evolution reaction(HER),which can benefit from a long-term reconstruction during HER for 10 h to continuously increase the *** final catalyst(e-RuNiPO)shows a huge morphology change from bulk sphere to highly exposed layered structure in the electrocatalysis process,and exhibits an interesting electronic structure modification with the electron transfer from Ru to Ni for better interfacial interaction and quick charge *** to the favorable morphology with more exposed active sites and the optimized electronic structure,the final catalyst can achieve an outstanding performance with only an overpotential of 15 mV at 10 mA cm^(-2)(with a good stability more than 100 h),even outperforming the performance of benchmark 20 wt%Pt/C catalyst(18 mV at 10 mA cm^(-2))by using a much lower Ru content.

关键词： Electrocatalyst Electrochemical reconstruction Hydrogen evolution reaction X-ray absorption spectroscopy