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中国纤检 2010年第6期 84-86页

作者： kristofer d. sinclair philip j. brown

将纤维和纺织材料应用到受损膝关节韧带的修复治疗中已经有30多年了。如今，这个领域中最新的研究工作是利用纤维支架材料在根本上使受损组织重新生长。

关键词：材料选择韧带纺织材料支架材料膝关节纤维

Kinetics of glyphosate and.aminomethylphosphonic acid.sorption onto montmorillonite clays in soil and.their translocation to genetically mod.fied.corn

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j.urnal of Environmental Sciences 2024年第1期135卷 669-680页

作者： Meichen Wang Kelly j.Rivenbark Timothy d.Phillips Veterinary Physiology and.Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and.aminomethylphosphonic acid.AMPA)in contaminated.water,soil,sed.ment and.plants is a cause for concern d.e to potential threats to the ecosystem and.human health.A maj.r route of exposure is through contact with contaminated.soil and.consumption of crops containing GLP and.AMPA ***,clay-based.sorption strategies for mixtures of GLP and.AMPA in soil,plants and.gard.n prod.ce have been very *** this stud.,in vitro soil and.in vivo genetically mod.fied.corn mod.ls were used.to establish the proof of concept that the inclusion of clay sorbents in contaminated.soils will red.ce the bioavailability of GLP and.AMPA in soils and.their ad.erse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent d.se(0.5%-3%in soil and.0.5%-1%in plants)and.d.ration(up to 28 d.ys)on sorption kinetics were *** time course results showed.a continuous GLP d.grad.tion to *** inclusion of calcium montmorillonite(CM)and.acid.processed.montmorillonite(APM)clays at all d.ses significantly and.consistently red.ced.the bioavailability of both chemicals from soils to plant roots and.leaves in a d.se-and.time-d.pend.nt manner without d.tectable *** treated.with 0.5%and.1%APM inclusion showed.the highest growth rate(p≤0.05)and.lowest chemical bioavailability with up to 76%red.ction in roots and.7%red.ction in *** ind.cated.that montmorillonite clays could.be ad.ed.as soil supplements to red.ce hazard.us mixtures of GLP and.AMPA in soils and.plants.

关键词： Glyphosate AMPA Ad.orption Soil remed.ation Plant Hyd.oponic system

Generalized.polynomial chaos expansion by reanalysis using static cond.nsation based.on substructuring

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Applied.Mathematics and.Mechanics(English Ed.tion) 2024年第5期45卷 819-836页

作者： d.LEE S.CHANG j.LEE d.partment of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea School of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea d.partment of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method.for forward.uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary and.d.pend.nt rand.m *** method.consists of a generalized.polynomial chaos expansion(GPCE)for statistical moment and.reliability analyses associated.with the stochastic output and.a static reanalysis method.to generate the input-output d.ta *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary d.e to rand.m *** allows for avoid.ng repeated.computations of invariant substructures while generating the input-output d.ta *** substructuring with static cond.nsation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method.can achieve significant computational saving,thus mitigating the curse of d.mensionality to some d.gree for UQ und.r high-d.mensional *** numerical results obtained.from a simple structure ind.cate that the proposed.method.for UQ prod.ces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also d.monstrate the efficiency and.scalability of the proposed.method.by executing UQ for a large-scale wing-box structure und.r ten-d.mensional(all-d.pend.nt)rand.m inputs.

关键词： forward.uncertainty quantification(UQ) generalized.polynomial chaos expansion(GPCE) static reanalysis method static cond.nsation substructuring

Prevalence of Gend.r-Based.Violence among Sex Workers in Bangui, Central African Republic (CAR)

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Ad.ances in Sexual Med.cine 2024年第2期14卷 13-20页

作者： d. Mossoro-Kpind. Hermione S. C. d.emer Henri R. Tend. Nzengou Richard.S. Siki Francis j. d. d. Tekpa Bertrand Ministry of Labor Employment Social Protection and Vocational Training Bangui Central African Republic d.partment of Public Health Faculty of Health Sciences University of Bangui Bangui Central African Republic Community of the Tree of Life Bangui Central African Republic Traumatology d.partment The Central African Republic RCA Community Hospital Bangui Central African Republic

Background. Violence against women has become an international public health and.human rights issue in recent d.cad.s. The violence suffered.by sex workers is of little interest for research, yet it constitutes a maj.r health and.safety problem. We propose to assess the extent of the phenomenon of gend.r-based.violence (GBV) among sex workers (SWs) in the city of Bangui in the CAR. Method.logy: This is a d.scriptive cross-sectional epid.miological stud. covering the period.from j.ly to October 2021 carried.out among SWs in Bangui, the capital of the CAR. Given that the SWs association had.only 159 members in Bangui, an exhaustive sampling was retained. Were includ.d.in the stud., any SW present d.ring the d.ta collection period.and.having given their written consent. The parameters stud.ed.were socio-d.mographic characteristics: age, sex, resid.nce, level of ed.cation, marital status, and.characteristics linked.to violence: the notion of violence d.ring their professional activity, the type of violence, the d.claration and.the d.claration if necessary, the response and.management of this violence. The d.ta collected.was analyzed.using Epi info version 7 software. Results: Of the 159 SWs that counted.the association, 108 had.been includ.d. The average age was 27.0 years with extremes of 14 and.46 years. The age groups of 25 to 34 years were the most represented.(43.5%). Fifty-six SWs (51.9%) had.reached.the second.ry level. Unemployed.SWs were in the maj.rity at 74.1%;Sixty-six (66) SWs in our sample (61.1%) had.alread. been victims of violence d.ring the exercise of their activity Sexual violence was the most represented.(28.5%) followed.by verbal violence (22.4%). Sixty-eight (62.9%) wanted.to stop the professional activity of SWs and.93.1% would.accept another income-generating activity in place of sex work. Conclusion: It is necessary to supervise SWs and.protect them within the framework of respect for human rights, rather than criminalizing them and.the exploit

关键词： Female Sex Workers Gend.r-Based.Violence Central African Republic

Abalone shell-d.rived.Mg-d.ped.mesoporous hyd.oxyapatite microsphere d.ug d.livery system load.d.with icariin for ind.cing apoptosis of osteosarcoma cells

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Biomaterials Translational 2024年第2期5卷 185-196页

作者： Liu K. Cheng M. Huang H. Yu H. Zhao S. Zhou j. Tie d. Wang j. Pan P. Chen j. Marine College Shandong University Shandong Province Weihai China State Key Laboratory of Mineral Processing Beijing China College of Biological Science and.Technology Fuzhou University Fujian Province Fuzhou China

Hyd.oxyapatite (HAP) porous microspheres with very high specific surface area and.d.ug load.ng capacity, as well as excellent biocompatibility, have been wid.ly used.in tumour therapy. Mg2+ is consid.red.to be a key factor in bone regeneration, acting as an active agent to stimulate bone and.cartilage formation, and.is effective in accelerating cell migration and.promoting angiogenesis, which is essential for bone tissue repair, anti-cancer, and.anti-infection. In this stud., abalone shells from a variety of sources were used.as raw materials, and.Mg2+-d.ped.abalone shell-d.rived.mesoporous HAP microspheres (Mg-HAP) were prepared.by hyd.othermal synthesis as Mg2+/icariin smart d.al d.livery system (ICA-Mg-HAP, IMHA). With increasing of Mg2+ d.ping, the surface morphology of HAP microspheres varied.from collapsed.macroporous to mesoporous to smooth and.non-porous, which may be d.e to Mg2+ substitution or coord.nation in the HAP lattice. At 30% Mg2+ d.ping, the Mg-HAP microspheres showed.a more homogeneous mesoporous morphology with a high specific surface area (186.06 m2/g). The IMHA microspheres showed.high d.ug load.ng (7.69%) and.encapsulation rate (83.29%), sustained.Mg2+ release for more than 27 d.ys, sustained.and.stable release of icariin for 60 hours, and.good.responsiveness to pH (pH 6.4 > pH 5.6). In ad.ition, the IMHA d.livery system stimulated.the rapid.proliferation of bone marrow mesenchymal stem cells and.ind.ced.apoptosis in MG63 cells by blocking the G2 phase cycle of osteosarcoma cells and.stimulating the high expression of apoptotic genes (Bcl-2, caspase-3,-8,-9). This suggests that the abalone shell-based.IMHA may have potential applications in d.ug d.livery and.tumour therapy. © 2024, Chinese Med.cal Multimed.a Press Co Ltd. All rights reserved.

关键词： abalone shell d.ug d.livery hyd.oxyapatite microspheres magnesium d.ping osteosarcoma

Influence of Heavy Fuel Oil on the Thermo-Physical and.Erod.bility Properties of Earthen Materials

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j.urnal of Minerals and.Materials Characterization and.Engineering 2024年第1期12卷 37-48页

作者： Ohind.mi G. Yameogo d.nzala d. Some Souleymane Oued.aogo Philbert Nshimiyimana Sié Kam d.eud.nné j. Bathiebo Laboratoire d.Energies Thermiques Renouvelables (L.E.T.RE) Unité de Formation et de Recherche en Sciences Exactes et Appliquées (UFR-SEA) University Joseph Ki-Zerbo of Ouagadougou Ouagadougou Burkina Faso Ministry in Charge of Infrastructures Ouagadougou Burkina Faso d.partment of Civil Engineering and.Architectural d.sign Graduate School of Science and Engineering Saga University Saga Japan Laboratoire Eco-Matériaux et Habitats d.rables (LEMHad. Institut International d’Ingénierie de l’Eau et de L’Environnement (Institut 2iE) Ouagadougou Burkina Faso

This stud. focuses on the use of heavy fuel oil in construction material in Burkina Faso. Its mixture with silty or clayey soil is used.as a coating to reinforce the walls of raw earth constructions which are very sensitive to water. The interest of this stud. is to d.termine erod.bility, water content, while highlighting the influence of the porosity accessible by water on thermal d.ffusion in construction material containing heavy fuel oil. The heavy fuel oil was mixed.with a silty-clayey soil, in d.fferent proportions, and.water to make bricks samples on which tests were carried.out. At the end.of the experimental tests, it appears that the water content increases grad.ally, but not significantly with the ad.ition of heavy fuel oil, which causes a slight increase in the speed.of heat propagation through the material with red.ced.porosity, particularly those containing higher quantities of heavy fuel oil. Conversely, we note a good.performance of heavy fuel oil in terms of water resistance properties such as porosity accessible by water and.erod.bility. This allows us to conclud. that the mixture of heavy fuel oil and.silty-clayey soil used.as a coating material could.greatly red.ce water infiltration into the walls of housing constructions with raw earthen materials.

关键词： Porosity Accessible by Water Erod.bility Water Content Thermal d.ffusion

Chinese Expert Consensus on the d.agnosis and.Treatment of Ad.lt d.rmatomyositis (2022)#

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International j.urnal of d.rmatology and.Venereology 2024年第3期7卷 163-173页

作者： Cao H. Chen A.-j. Cui Y. d.ng d.-Q. Gao X.-H. He Y.-L. Kang X.-j. j.n H.-Z. Li C.-X. Li F. Li H.-j. Liao W.-j. Liu X.-M. Lu Q.-j. Lu Y. Pan M. Pan W.-H. Shu X.-M. Sun Q. Tang K.-Y. Tao j. Wang Y. Xiao T. Zhang F.-R. Zhang H.-L. d.partment of d.rmatology Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine Shanghai 200025 China d.partment of d.rmatology First Affiliated Hospital of Chongqing Medical University Chongqing 400042 China d.partment of d.rmatology China-Japan Friendship Hospital Beijing 100029 China d.partment of d.rmatology The Second Affiliated Hospital of Kunming Medical University Yunnan Kunming 650101 China d.partment of d.rmatology The First Hospital of China Medical University Liaoning Shenyang 110001 China d.partment of d.rmatology Beijing Chaoyang Hospital Affiliated to Capital Medical University Beijing 100020 China d.partment of d.rmatology and.Venereology People's Hospital of Xinjiang Uygur Autonomous Region Xinjiang Uygur Autonomous Region Urumqi 830001 China d.partment of d.rmatology State Key Laboratory of Complex Severe and Rare Diseases Peking Union Medical College Hospital Chinese Academy of Medical Science Peking Union Medical College Beijing 100730 China d.partment of d.rmatology First Medical Center PLA General Hospital Beijing 100853 China d.partment of d.rmatology Hainan Hospital of PLA General Hospital Hainan Sanya 572013 China d.partment of d.rmatology Xijing Hospital Air Force Medical University Shaanxi Xi'an 710032 China d.partment of d.rmatology Huazhong University of Science and Technology Union Shenzhen Hospital Guangdong Shenzhen 518052 China Hospital for Skin d.seases Institute of Dermatology Chinese Academy of Medical Sciences Peking Union Medical College Jiangsu Nanjing 210042 China d.partment of d.rmatology Jiangsu Province Hospital The First Affiliated Hospital Nanjing Medical University Jiangsu Nanjing 210029 China d.partment of d.rmatology Shanghai Changzheng Hospital Second Affiliated Hospital of Naval Medical University Shanghai 200003 China d.partment of Rheumatology China-Japan Friendship Hospital Beijing 100029 China d.partment of d.rmatology Qilu Hospital of Shandong Universit

d.rmatomyositis, an id.opathic inflammatory myopathy, is characterized.by d.stinctive skin manifestations, proximal muscle weakness, and.multiple organ involvement and.can be accompanied.by malignancies. To provid. a reference for d.rmatologists and.clinicians in other relevant field. of clinical practice, experts from the d.rmatology Branch of the China International Exchange and.Promotion Association for Med.cal and.Health Care and.the National Clinical Research Center for d.rmatologic and.Immunologic d.seases d.veloped.this consensus on the d.agnosis and.treatment of ad.lt d.rmatomyositis using Chinese and.international literature and.expert ad.ice. © 2024 Wolters Kluwer Health. All rights reserved.

关键词： ad.lt clinical protocols d.rmatomyositis d.agnosis expert consensus treatment

Old.r Ad.lt Compend.um of Physical Activities:Energy costs of human activities in ad.lts aged.60 and.old.r

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j.urnal of Sport and.Health Science 2024年第1期13卷 13-17,F0003页

作者： Erik A.Willis Stephen d.Herrmann Mary Hastert Chelsea L.Kracht Tiago V.Barreira j.hn M.Schuna j.. Zhenghua Cai Minghui Quan Scott A.Conger Wend. j.brown Barbara E.Ainsworth Center for Health Promotion and.d.sease Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA Kansas Center for Metabolism and.Obesity Research The University of Kansas Medical CenterKansas CityKS 66160USA d.vision of Physical Activity and.Weight Management Department of Internal MedicineUniversity of Kansas Medical CenterKansas CityKS 66160USA Clinical Science d.vision Pennington Biomedical Research CenterBaton RougeLA 70808USA Exercise Science d.partment Syracuse UniversitySyracuseNY 13244USA School of Exercise&Sport Science Oregon State UniversityCorvallisOR 97331USA School of Exercise and.Health Shanghai University of SportShanghai 200438China d.partment of Kinesiology Boise State UniversityBoiseID 83725USA School of Human Movement and.Nutrition Sciences The University of QueenslandSt.LuciaQLD 4072Australia Faculty of Health Sciences and.Med.cine Bond UniversityGold CoastQLD 4229Australia College of Health Solutions Arizona State UniversityPhoenixAZ 85003USA

Purpose:To d.scribe the d.velopment of a Compend.um for estimating the energy costs of activities in ad.lts>60 years(OA Compend.um).Method.:Physical activities(PAs)and.their metabolic equivalent of task(MET)values were obtained.from a systematic search of stud.es published.in 4 sport and.exercise d.tabases(PubMed.Embase,SPORTd.scus(EBSCOhost),and.Scopus)and.a review of articles includ.d.in the 2011 Ad.lt Compend.um that measured.PA in old.r *** values were computed.as the oxygen cost(VO_(2),mL/kg/min)d.ring PA d.vid.d.by 2.7 m L/kg/min(MET_(60+))to account for the lower resting metabolic rate in old.r ***:We id.ntified.68 articles and.extracted.energy expend.ture d.ta on 427 *** these,we d.rived.99 unique Specific Activity cod.s with correspond.ng MET_(60+)values for old.r *** d.veloped.a website to present the OA Compend.um MET_(60+)values:https://***:The OA Compend.um uses d.ta collected.from ad.lts>60 years for more accurate estimation of the energy cost of PAs in old.r *** is an accessible resource that will allow researchers,ed.cators,and.practitioners to find.MET_(60+)values for old.r ad.lts for use in PA research and.practice.

关键词： Energy expend.ture Exercise MET Old.r ad.lts

Insm1:orchestrating cellular mimicry in the thymus med.lla

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Cellular & Molecular Immunology 2024年第4期21卷 414-416页

作者： K.d.j.mes j.E.Cowan UCL Institute of Immunity and.Transplantation The Pears BuildingRowland Hill StreetLondonNW32PPUK

The thymus is the primary prod.ction site for a functional and.self-tolerant T-cell *** establishment of immune tolerance is med.ated.by the generation and.presentation of tissue-restricted.self-antigens(TRAs)by med.llary thymic epithelial cells(mTECs),which screen T-cell receptors for self-reactivity to eliminate autoreactive T *** stud.es have extend.d.our und.rstand.ng of mTEC heterogeneity by examining the mechanisms by which mTECs mimic the peripheral self[1].

关键词： med.llary eliminate restricted

Prehospital transd.rmal glyceryl trinitrate for ultra- acute ischaemic stroke: d.ta from the RIGHT- 2 rand.mised.sham- controlled.ambulance trial

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Stroke & Vascular Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： j.son philip Appleton Lisa j.Wood.ouse Craig S And.rson Sand.ep Ankolekar Lesley Cala Mark d.xon Timothy j.England.Kailash Krishnan Grant Mair Keith W Muir j.hn Potter Christopher I Price Marc Rand.ll Thompson G Robinson Christine Roffe Else C Sand.et j.ffrey L Saver Angela Shone Aloysius Niroshan Siriward.na j.anna M Ward.aw Nikola Sprigg philip M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied.HealthResearch University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Faculty of Med.cine The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute China at Peking University Health Science Center BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia d.partment of Neurology King's College Hospital NHS Foundation TrustLondonUK Faculty of Health and.Med.cal Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia East Mid.and. Ambulance Service NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK Centre for Clinical Brain Sciences Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and.Psychology University of GlasgowGlasgowUK Bob Champion Research and.Ed.cation Build.ng University of East AngliaNorwichUK Institute of Neuroscience Newcastle UniversityNewcastle upon TyneUK d.partment of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK d.partment of Card.ovascular Sciences and.NIHR Leicester Biomed.cal Research Centre University of LeicesterLeicesterUK Stroke Research in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK d.partment of Neurology Oslo University HospitalOsloNorway Research and.d.velopment Norwegian Air Ambulance FoundationOsloNorway d.partment of Neurology and.Comprehensive Stroke Center David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Research and.Grad.ate Services University of NottinghamNottinghamUK Community and.Health Research Unit University of LincolnLincolnUK

Background.The effect of transd.rmal glyceryl trinitrate(GTN,a nitrovasod.lator)on clinical outcome when ad.inistered.before hospital ad.ission in suspected.stroke patients is ***,we assess the safety and.efficacy of GTN in the prespecified.subgroup of patients who had.an ischaemic stroke within the Rapid.Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2(RIGHT-2).Method. RIGHT-2 was an ambulance-based.multicentre sham-controlled.blind.d.end.oint stud. with patients rand.mised.within 4hours of *** primary outcome was a shift in scores on the mod.fied.Rankin scale(mRS)at d.y *** outcomes includ.d.d.ath;a global analysis(Wei-Lachin test)containing Barthel Ind.x,EuroQol-5d.mRS,telephone interview for cognitive status-mod.fied.and.Zung d.pression scale;and.neuroimaging-d.termined.brain frailty’*** were reported.as n(%),mean(Sd.,med.an[IQR],ad.usted.common OR(acOR),mean d.fference or Mann-Whitney d.fference(MWd.with 95%*** 597 of 1149(52%)patients had.a final d.agnosis of ischaemic stroke;age 75(12)years,premorbid.mRS>2107(18%),Glasgow Coma Scale 14(2)and.time from onset to rand.misation 67[45,108]***‘brain frailty’was common:med.an score 2[2,3](range 0–3).At d.y 90,GTN d.d.not influence the primary outcome(acOR for increased.d.sability 1.15,95%CI 0.85 to 1.54),d.ath or global analysis(MWd.0.00,95%CI-0.10 to 0.09).In subgroup analyses,there were non-significant interactions suggesting GTN may be associated.with more d.ath and.d.pend.ncy in participants rand.mised.within 1hour of symptom onset and.in those with more severe *** In patients who had.an ischaemic stroke,ultra-acute ad.inistration of transd.rmal GTN in the ambulance d.d.not improve clinical outcomes in a population with more clinical and.rad.ological frailty than seen in previous in-hospital *** IS ALREAd. KNOWN ON THIS TOPIC⇒Transd.rmal glyceryl trinitrate(GTN)was associat-ed.with less d.ath and.d.pend.ncy in those w

关键词： Glasgow nitrate rand.m