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Terrestrial records of the early Albian Ocean Anoxic Event:Evidence from the Fuxin lacustrine basin,NE China

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Geoscience Frontiers 2022年第1期13卷 138-157页

作者： Xiao-Tao Xu Long-Yi Shao Kenneth A.eriksson Bo Pang Shuai Wang Cheng-Xue Yang Hai-Hai Hou College of Geoscience and Surveying Engineering China University of Mining and Technology(Beijing)Beijing 100083China Shandong Key Laboratory of Depositional Mineralization&Sedimentary Mineral Shandong University of Science and TechnologyQingdao 266590China Department of Geosciences Virginia TechBlacksburgVA 24061USA Liaoning Province Geology and Minerals Group Energy Geology Co. Ltd.Shenyang 110000China Institute of Earth Sciences China University of Geosciences(Beijing)Beijing 100083China College of Mining Liaoning Technical UniversityFuxin 123000China

The early Albian Oceanic Anoxic Event 1 b(OAE 1 b) is well documented in the Tethys, Pacific and North Atlantic, but few studies have evaluated whether or not terrestrial records of OAE 1 b exist. In order to identify terrestrial records of the early Albian OAE 1 b and to infer possible driving mechanisms, an integrated multi-proxy study from the late Aptian to Albian in the Fuxin lacustrine basin was conducted,including thick, organic-rich black mudstones, total organic carbon(TOC), organic carbon isotopes(d13 Corg), mercury concentration(Hg) and results from pyrolysis analyses(S2, Tmaxand HI). Results show three distinct short-term negative d13 Corgexcursions corresponding with relatively high TOC values,which could be counterparts of the Kilian, Paquier and Leenhardt sub-events of the early Albian OAE1 b. Atmospheric CO2 concentration(p CO2) recovered from C3 plant d13 Corgcompositions indicates an increasing trend in Unit C during the early Albian, and there are three short-term increases of p CO2 corresponding to the three sub-events of OAE 1 b at this time interval. We infer that a trend of increasing p CO2 during the Kilian sub-event in the study area is closely related to volcanism. Continental weathering calculated using chemical weathering indices(CIA, WIP and MIA(O)) show an increasing trend during the OAE 1 b interval, likely resulting from warmer and more humid conditions. Mixed sources of terrestrial plants and lacustrine plankton demonstrated by pyrolysis analyses(HI vs. Tmaxand S2 vs. TOC), indicate a terrestrial contribution to the organic-rich sediments of the Kilian, Paquier and Leenhardt sub-events of OAE 1 b. We suggest that a CO2-forced greenhouse effect during the early Albian might have triggered the relatively warm and humid palaeoclimatic conditions, and intensified chemical weathering that combined to create high nutrient and organic matter levels that were flushed into lakes contributing to eutrophication and anoxia in lacustrine and in c

关键词： Fuxin Basin Early Albian Organic carbon isotopes Ocean Anoxic Event 1b Terrestrial records

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Special focus on learning and real-time optimization of automotive powertrain systems

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Science China(Information Sciences) 2018年第7期61卷 5-5页

作者： Tielong SHEN Lars eriksson Sophia University Linkping University

The control of automotive powertrain systems is challenging for dynamical systems theory and control technology because of the complexity,uncertainty,and stochasticity in the *** mass production of a specified powertrain,normally over millions,a robust calibration of the electrical control unit(ECU)is the first ***,since the operating environment always changes rapidly and the lifetime of a vehicle is longer,the pre-calibrated ECU parameter cannot guarantee the optimality of

关键词： ECU Special focus on learning and real-time optimization of automotive powertrain systems

Impact of switching from ranibizumab to aflibercept on the number of intravitreous injection and follow up visit in wet AMD:results of real life ELU study

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International Journal of Ophthalmology(English edition) 2020年第2期13卷 252-256页

作者： Frederic Queguiner kristina Bezirganyan Jean Christophe Courjaret Laurence Curel Guillaume Penaranda Maud Righini Chossegros Ophthalmology and Clinical Research Departments Hopital Saint JosephMarseille F-13008France Biostatistics Department Alphabio LaboratoryMarseille F-13003France

●AIM:To study if one of the two molecules could lead to a lower number of follow up visits and intra-vitreous injection(IVI)with the same efficacy.●METHODS:ELU(or"elected"in French)study is a retrospective study conducted in real life in patients presenting suboptimal response after ranibizumab IVI(phase 1)and secondary switched to aflibercept(phase 2).The number of follow up visits and IVI were compared in both *** acuity(VA)evolution and"switching"reasons were secondary analyzed.●RESULTS:We retrospectively included data of 33 patients(38 eyes)with age-related macular degeneration(AMD;mean age:77±7.7 y).The number of monthly follow up visits[median(Q1;Q3)]:was significantly lower with aflibercept(phase 2),respectively 1.0(0.81;1.49)visits in phase 1,versus 0.79(0.67;0.86)visits in phase *** median number of monthly IVI also significantly decreased in phase 2,respectively 0.67(0.55;0.90)IVI in phase 1,versus 0.55(0.45;0.67)IVI in phase *** mean VA evolution(VA final-VA initial)was similar in both phases,(P>0.05).Whatever the reason for"switching"(loss of efficacy,tachyphylaxis,tolerance problems),there was no incidence on VA evolution over the time.●CONCLUSION:Our results show that switching from ranibizumab to aflibercept in"suboptimal"patients significantly reduce the number of follow up visits and IVI,with a comparable *** decrease in visit number could improve patients’quality of life and reduce surgical risk by reducing the number of injections.

关键词： wet age-related macular degeneration anti-VEGF aflibercept ranibizumab follow up visit intravitreal injection visual acuity

Polydopamine-based redox-active separators for lithium-ion batteries

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Journal of Materiomics 2019年第2期5卷 204-213页

作者： Ruijun Pan Zhaohui Wang Rui Sun Jonas Lindh kristina Edstrom Maria Strømme Leif Nyholm Department of Chemistry-Ångstr€om Laboratory Uppsala UniversityBox 538SE-75121UppsalaSweden Nanotechnology and Functional Materials Department of Engineering SciencesTheÅngstr€om LaboratoryUppsala UniversityBox 534SE-75121UppsalaSweden

The performance of lithium-ion batteries(LIBs)can be effectively enhanced with functionalized ***,it is demonstrated that polydopamine-based redox-active(PRA)separators can provide additional capacity to that of typical anode materials,increase the volumetric capacity of the cell,as well as,decrease the cell resistance to yield an improved performance at higher cycling *** PRA separators,which are composed of a 2 mm thick electrically insulating nanocellulose fiber(NCF)layer and an 18 mm thick polydopamine(PDA)and carbon nanotube(CNT)containing redox-active layer,are readily produced using a facile paper-making *** PRA separators are also easily wettable by commonly employed electrolytes(***40)and exhibit a high dimensional *** addition,the pore structure endows the PRA separator with a high ionic conductivity(i.e.1.06 mS cm^(-1))that increases the rate performance of the *** to the presence of the redox-active layer,Li_(4)Ti_(5)O_(12)(LTO)half-cells containing PRA separator were found to exhibit significantly higher capacities than the corresponding cells containing commercial *** results clearly show that the implementation of this type of redox-active separators constitutes a straightforward and effective way to increase the energy and power densities of LIBs.

关键词： Lithium-ion battery Separator Cellulose Polydopamine Redox-active

Predisposing factors for atrial fibrillation in the elderly

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Journal of Geriatric Cardiology 2017年第3期14卷 179-184页

作者： kristina Wasmer Lars Eckardt Gunter Breithardt Division of Electrophysiology Department of Cardiovascular Medicine University Hospital Miinster Germany

Atrial fibrillation （AF） in the elderly occurs as a consequence of cardiovascular aging and an age related increase of comorbidity. Several predisposing factors for AF have been identified for the overall AF population. Most of them, cardiovascular disease in particular, play a role in younger and older patients. The longer time period during which these risk factors can cause structural changes that ultimately lead to AF may, at least in part, explain the association between age and AF. In addition, less well defined age-related changes in cellular electrophysi- ologic properties and structure predispose to AF in the elderly.

关键词： Atrial fibrillation Atrial fibrosis Mechanisms Risk factors Stroke The elderly

Impact of creatinine methodology on glomerular filtration rate estimation in diabetes

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World Journal of Diabetes 2017年第5期8卷 222-229页

作者： Marijana Vucic Lovrencic Vanja Radisic Biljak kristina Blaslov Sandra Bozicevic Lea Smircic Duvnjak Department of Laboratory Medicine Merkur University Hospital Vuk Vrhovac University Clinic Merkur University Hospital

AIM To evaluate the influence of creatinine methodology on the performance of chronic kidney disease(CKD)-Epidemiology Collaboration Group-calculated estimated glomerular filtration rate(CKD-EPI-eGFR) for CKD diagnosis/staging in a large cohort of diabetic patients. METHODS Fasting blood samples were taken from diabetic patients attending our clinic for their regular annual examination, including laboratory measurement of serum creatinine and *** Our results indicated an overall excellent agreement in CKD staging(kappa = 0.918) between the Jaffé serum creatinine-and enzymatic serum creatinine-based CKDEPI-eGFR, with 9% of discordant cases. As compared to the enzymatic creatinine, the majority of discordances(8%) were positive, i.e., associated with the more advanced CKD stage re-classification, whereas only 1% of cases were negatively discordant if Jaffé creatinine was used for eGFR calculation. A minor proportion of the discordant cases(3.5%) were re-classified into clinically relevant CKD stage indicating mildly to moderately decreased kidney function(< 60 m L/min per 1.73 m^2). Significant acute and chronic hyperglycaemia, assessedas plasma glucose and Hb A1 c levels far above the recommended glycaemic goals, was associated with positively discordant cases. Due to a very low frequency, positive discordance is not likely to present a great burden for the health-care providers, while intensified medical care may actually be beneficial for the small number of discordant patients. On the other hand, a very low proportion of negatively discordant cases(1%) at the 60 m L/min per 1.73 m^2 eGFR level indicate a negligible possibility to miss the CKD diagnosis, which could be the most prominent clinical problem affecting patient care, considering high risk of CKD for adverse patient outcomes. CONCLUSION This study indicate that compensated Jaffé creatinine procedure, in spite of the glucose-dependent bias, is not inferior to enzymatic creatinine in CKD diagnosis/

关键词： Diabetes Estimated glomerular filtration rate Chronic kidney disease-Epidemiology Collaboration Group Creatinine Enzymatic method Chronic kidney disease Impact Compensated Jaffé method

Performance of silver nanoparticles in the catalysis of the oxygen reduction reaction in neutral media： Efficiency limitation due to hydrogen peroxide escape

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Nano Research 2013年第7期6卷 511-524页

作者： Christopher C. M. Neumann Eduardo Laborda kristina Tschulik Kristopher R. Ward Richard G. Compton Department of Chemistry Physical and Theoretical Chemistry Laboratory Oxford University South Parks Road Oxford OXl 3QZUnited Kingdom

The electrocatalytic activity for oxygen reduction reaction （ORR） at neutral pH of citrate-capped silver nanoparticles （diameter = 18 nm） supported on glassy carbon （GC） is investigated voltammetrically. Novelly, the modification of the substrate by nanoparticles sticking to form a random nanoparticle array and the voltammetric experiments are carried out simultaneously by immersion of the GC electrode in an air-saturated 0.1 M NaC104 solution （pH = 5.8） containing chemically-synthesized nanoparticles. The experimental voltammograms of the resulting nanoparticle array are simulated with homemade programs according to the two-proton, two-electron reduction of oxygen to hydrogen peroxide where the first electron transfer is rate determining. In the case of silver electrodes, the hydrogen peroxide generated is partially further reduced to water via heterogeneous decomposition. Comparison of the results obtained on a silver macroelectrode and silver nanoparticles indicates that, for the silver nanoparticles and particle coverages （0.035%-0.457%） employed in this study, the ORR electrode kinetics is slower and the production of hydrogen peroxide larger on the glassy carbon-supported nanoparticles than on bulk silver.

关键词： oxygen reduction reaction silver nanoparticles nanoelectrocatalysis hydrogen peroxide escape fuel cells

Differential aberrant connectivity of precuneus and anterior insula may underpin the diagnosis of schizophrenia and mood disorders

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World Journal of Psychiatry 2021年第12期11卷 1274-1287页

作者： Katrin Aryutova Rositsa Paunova Sevdalina Kandilarova kristina Stoyanova Michael HJ Maes Drozdstoy Stoyanov Psychiatry and Medical Psychology Medical UniversityPlovdiv 4002Bulgaria Research Institute Medical UniversityPlovdiv 4002Bulgaria

BACKGROUND Over the past decade,resting-state functional magnetic resonance imaging(rsfMRI)has concentrated on brain networks such as the default mode network(DMN),the salience network(SN),and the central executive network(CEN),allowing for a better understanding of cognitive deficits observed in mental disorders,as well as other characteristic psychopathological phenomena such as thought and behavior *** To investigate differential patterns of effective connectivity across distributed brain networks involved in schizophrenia(SCH)and mood *** The sample comprised 58 patients with either paranoid syndrome in the context of SCH(n=26)or depressive syndrome(Ds)(n=32),in the context of major depressive disorder or bipolar *** methods used include rs-fMRI and subsequent dynamic causal modeling to determine the direction and strength of connections to and from various nodes in the DMN,SN and *** A significant excitatory connection from the dorsal anterior cingulate cortex to the anterior insula(aI)was observed in the SCH patient group,whereas inhibitory connections from the precuneus to the ventrolateral prefrontal cortex and from the aI to the precuneus were observed in the Ds *** The results delineate specific patterns associated with SCH and Ds and offer a better explanation of the underlying mechanisms of these disorders,and inform differential diagnosis and precise treatment targeting.

关键词： Schizophrenia Major depressive disorder Bipolar disorder Resting-state functional magnetic resonance imaging effective connectivity precuneus insula default mode network salience network

药用植物内生芽孢杆菌的多样性和系统发育研究

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微生物学报 2008年第4期48卷 432-438页

作者：陈兰张小平 kristina Lindstrom 四川农业大学资源环境学院雅安625000 Department of Applied Chemistry and Microbiology University of HelsinkiHelsinki 00014Finland

【目的】了解药用植物内生芽孢杆菌的生物多样性。【方法】采用数值分类、16S rDNA PCR-RFLP、BOX-PCR指纹图谱和16S rDNA序列分析技术对分离于几种药用植物的内生芽孢杆菌和已知参比菌株进行表型、遗传多样性及系统发育研究。【结果】... 详细信息

【目的】了解药用植物内生芽孢杆菌的生物多样性。【方法】采用数值分类、16S rDNA PCR-RFLP、BOX-PCR指纹图谱和16S rDNA序列分析技术对分离于几种药用植物的内生芽孢杆菌和已知参比菌株进行表型、遗传多样性及系统发育研究。【结果】供试菌株在数值分类聚类分析中在84%的相似水平上产生13个表观群。16S rDNA PCR-RFLP分析表明供试菌株表现出丰富的遗传多样性。BOX-PCR指纹图谱分析进一步证明药用植物的内生芽孢杆菌的基因组也具有多样性,聚群的结果与数值分类有较好一致性。用软件在Genbank中进行所得序列的同源性检索,并构建系统发育树。由16S rDNA序列分析可知,供试的代表菌株SCAU11与球形芽孢杆菌(Bacillus sphaericus)亲缘关系最近,SCAU78和SCAU25为枯草芽孢杆菌(Bacillus subtilis)的两个亚种,代表菌株SCAU39与巨大芽孢杆菌(Bacillus megaterium)的亲缘关系最近。【结论】研究结果表明药用植物内生芽孢杆菌具有明显的表型和遗传多样性。

关键词：芽孢杆菌多样性数值分类 16S DNA PCR-RFLP BOX-PCR指纹图谱系统发育

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