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山东工业大学学报 1997年第1期27卷 11-15页

作者：孙康宁王昕张景德刘援朝尹衍升 MaslovkI 山东工业大学材料科学与工程学院俄罗斯声学显微中心

利用声学显微镜透视功能及测绘Ｖ（Ｚ）曲线的功能，跟踪Ｖ（Ｚ）曲线的变化，根据反馈回来的信息，快速、定位。

关键词：特种陶瓷陶瓷材料品质显微结构缺陷

局限性脉络膜血管瘤光动力治疗后持续性脉络膜肥厚

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世界核心医学期刊文摘（眼科学分册） 2006年第6期2卷 40-40页

作者： Hussain N. Das T. Mohan Ram L. S. Sumasri k. 王大江(译) 不详 Smt. kanuri Sa Itkamma Retina-vitreous Services L. V. Prasad Eye Institute L. V. Prasad Marg Banjara Hills Hyderabad 500 034 India

A 19-year-old man presented with blurred vision in the right eye,which was diagnosed as a circumscribed choroidal hemangioma. The choroidal thickening on B-scan ultrasonography persisted after receiving repeat photody... 详细信息

关键词：局限性脉络膜血管瘤光动力疗法持续性治疗后肥厚男性患者视物模糊维替泊芬肿瘤消退 B超检查

嘌呤受体P2Y13调节小胶质细胞形态、功能及白细胞介素-1β的释放水平

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神经损伤与功能重建 2019年第10期14卷 F0003-F0003页

作者： kyrargyri v Madry C Rifat A Arancibia-Carcamo IL Jones SP Chan vTT Xu Y Robaye B Attwell D 杜一星 Department of Neuroscience Physiology & Pharmacology University College London Department of Immunology Laboratory of Molecular Genetics Hellenic Pasteur Institute Institute of Neurophysiology Charité-Universitatsmedizin Berlin Faculté de Médecine Université Libre de Bruxelles 不详

小胶质细胞利用一系列膜受体来感知周围环境。虽然已知P2Y12受体在小胶质细胞的突起向释放ATP/ADP的损伤部位的靶向运动定中起关键作用,但对P2Y13的作用知之甚少。转录组数据表明P2Y13是小胶质细胞中第2高表达的神经递质受体。本研究显... 详细信息

小胶质细胞利用一系列膜受体来感知周围环境。虽然已知P2Y12受体在小胶质细胞的突起向释放ATP/ADP的损伤部位的靶向运动定中起关键作用,但对P2Y13的作用知之甚少。转录组数据表明P2Y13是小胶质细胞中第2高表达的神经递质受体。本研究显示,在缺乏P2Y13受体小鼠的急性脑切片,膜片钳记录由ADP激活P2Y12受体引起的THIk-1 k+电流密度增加了约50%。这种增加表明P2Y12依赖的趋化性反应增强。但是在P2Y13敲除小鼠,P2Y12介导的小胶质细胞突起向充灌ADP的电极或激光融蚀点聚集所需的时间更长。解剖分析表明,在P2Y13敲除小鼠中,小胶质细胞的密度没有变化,但分枝较少,突起长度较短。因此在基因敲除的小鼠,小胶质细胞趋化的突起必须进一步生长然后才能到达靶标,且脑部监视降低了约30%。在P2Y13敲除小鼠脑片中,阻断P2Y12受体并不会影响监视,表明监视过程不需要这些高亲和力受体的补充激活。令人惊讶的是,在P2Y13敲除小鼠白细胞介素-1β释放的基础值增加了5倍,而LPS和ATP引起的释放不受影响;P2Y13敲除小鼠完整脑中的小胶质细胞未被检测到激活。因此,尽管P2Y13受体与P2Y12非常接近,但它们在调节小胶质细胞形态和功能方面起着不同的作用。

关键词：二磷酸腺苷三磷酸腺苷嘌呤受体P2Y12 嘌呤受体P2Y13 嘌呤能信号传递

Measurement of the absolute branching fraction of D^+→k^0e^+v_e via k^0→π~0π~0

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Chinese Physics C 2016年第11期40卷 5-13页

作者：麦迪娜 M.N.Achasov 艾小聪 O.Albayrak M.Albrecht D.J.Ambrose A.Amoroso 安芬芬安琪白景芝 R.Baldini Ferroli 班勇 D.W.Bennett J.v.Bennett M.Bertani D.Bettoni 边渐鸣 F.Bianchi E.Boger I.Boyko R.A.Briere 蔡浩蔡啸 O.Cakir A.Calcaterra 曹国富 S.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈海云陈江川陈玛丽陈实陈申见谌炫陈旭荣陈元柏程和平褚新坤 G.Cibinetto 代洪亮代建平 A.Dbeyssi D.Dedovieh 邓子艳 A.Denig I.Denysenko M.Destefanis F.De Mori 丁勇董超董静董燎原董明义豆正磊杜书先段鹏飞范荆州方建房双世方馨方易 R.Farinelli L.Fava O.Fedorov F.Feldbauer G.Felici 封常青 E.Fioravanti M.Fritsch 傅成栋高清高鑫磊高旭阳高原宁高榛 I.Garzia k.Goetzen 龚丽龚文煊 W.Gradl M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭如盼郭玥郭玉萍 Z.Haddadi A.Hafner 韩爽郝喜庆 F.A.Harris 何康林 T.Held 衡月昆侯治龙胡琛胡海明胡继峰胡涛胡誉黄光顺黄金书黄性涛黄晓忠黄勇黄智玲 T.Hussain 纪全姬清平季晓斌季筱璐姜鲁文江晓山蒋兴雨焦健斌焦铮金大鹏金山 T.Johansson A.Julin N.kalantar-Nayestanaki 康晓琳康晓珅 M.kavatsyuk 柯百谦 P.kiese R.kliemt B.kloss O.B.kolcu B.kopf M.kornicer A.kupsc W.kühn J.S.Lange M.Lara P.Larin C.Leng 李翠李澄李德民李飞李峰云李刚李海波李惠静李家才李瑾李康李科李蕾李培荣李启云李腾李卫东李卫国李晓玲李小男李学潜李郁博李志兵梁昊梁勇飞梁羽铁廖广睿林德旭刘冰刘北江刘春秀刘栋刘福虎刘芳刘峰刘宏邦刘汇慧刘欢欢刘怀民刘杰刘建北刘觉平刘晶译刘凯刘魁勇刘兰雕刘佩莲刘倩刘树彬刘翔刘玉斌刘振安刘智青 H.Loehner 娄辛丑吕海江吕军光卢宇卢云鹏罗成林罗民兴 T.Luo 罗小兰吕晓睿马凤才马海龙马连良马明明马秋梅马天马旭宁马骁妍马玉明 F.E.Maas M.Maggiora 冒亚军毛泽普 S.Marcello J.G.Messchendorp 闵建闵天觉 R.E.Mitchell 莫晓虎莫玉俊 C.Morales Morales N.Yu.Muchnoi H.Muramatsu Y.Nefedov F.Nerling I.B.Nikolaev 宁哲 S.Nisar 牛顺利牛讯伊馬鵬欧阳群 S.Pacetti 潘越 P.Patteri M.Pelizaeus 彭海平 k.Peters J.Pettersson 平加伦平荣刚 R.Poling v.Prasad 漆红荣祁鸣钱森乔从丰秦丽清覃拈秦小帅秦中华邱进发 k.H.Rashid C.F.Redmer M.Ripka 荣刚 Ch.Rosner 阮向东 A.Sarantsev M.Savrie k.Schoenning S.Schumann 单葳邵明沈成平沈培迅沈肖雁盛华义施萌宋维民宋欣颖 S.Sosio S.Spataro 孙功星孙俊峰孙胜森孙新华孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.Tapan E.H.Thorndike M.Tiemens M.Ullrich I.Uman G.S.Yarner 王斌王滨龙王东王大勇王科王亮亮王灵淑王萌王平王佩良王炜王维平王雄飞王越王雅迪王贻芳王亚乾王铮王志刚王志宏王至勇王宗源 T.Weber 魏代会 P.Weidenkaff 文硕频 U.Wiedner M.Wolke 伍灵慧吴连近吴智夏磊夏力钢夏宇肖栋肖浩肖振军谢宇广修青磊许国发徐静静徐雷徐庆君徐庆年徐新平严亮鄢文标闫文成颜永红杨海军杨洪勋杨柳杨永栩叶梅叶铭汉殷俊昊俞伯祥喻纯旭俞洁晟苑长征袁文龙袁野 A.Yuncu A.A.Zafar A.Zallo 曾云曾哲张丙新张炳云张驰张长春张达华张宏浩章红宇张晋张佳佳 Institute of High Energy Physics G.I.Budker Institute of Nuclear Physics SB RAS BINP the Novosibirsk State University Carnegie Mellon University Bochum Ruhr-University University of Rochester University of Turin INFN University of Science and Technology of China State key Laboratory of Particle Detection and Electronics INFN Laboratori Nazionali di Frascati Peking University Indiana University INFN Sezione di Ferrara University of Minnesota Joint Institute for Nuclear Research the Moscow Institute of Physics and Technology Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan University Ankara University Istanbul Bilgi University the Functional Electronics Laboratory Tomsk State University Beihang University University of Chinese Academy of Sciences Nanjing University Lanzhou University Huangshan College Shanghai Jiao Tong University Helmholtz Institute Mainz Johannes Gutenberg University of Mainz Liaoning University Nankai University Zhengzhou University Tsinghua University University of Ferrara University of Eastern Piedmont GSI Helmholtzcentre for Heavy Ion Research GmbH Guangxi University Nanjing Normal University kvI-CART University of Groningen Henan Normal University University of Hawaii Uludag University Shandong University University of the Punjab Uppsala University Istanbul Axel University Justus-Liebig-Universitaet Giessen Ⅱ.Physikalisches Institut Seoul National University Hangzhou Normal University Beijing Institute of Petrochemical Technology Sun Yat-Sen University Sichuan University Guangxi Normal University Shanxi University Henan University of Science and Technology University of Texas at Dallas Zhejiang University G.I.Budker Institute of Nuclear Physics SB RAS(BINP) COMSATS Institute of Information Technology INFN and University of Perugia Goethe University Frankfurt the NRC "kurchatov Institute PNPI Near East University NicosiaNorth Cyprus Soochow University Hunan University University of South China China Center of Advanced Science and Technology B

By analyzing 2.93 fb-1 data collected at the center-of-mass energy v/S = 3.773 Gev with the BESIII detector, we measure the absolute branching fraction of the semileptonic decay D＋- k0e＋ ve via k0-π0π0 - （8.59 ± 0.14 ± 0.21）% using k0- k0-π0π0, where the first uncertainty is statistical and the second systematic. Our result is consistent with previous measurements within uncertainties..

关键词： charmed mesons semileptonic decays absolute branching fraction BESIII/BEPCII

Measurement of the integrated luminosities of the data taken by BESⅢ at √s=3.650 and 3.773 Gev

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Chinese Physics C 2013年第12期37卷 1-6页

作者：麦迪娜 M.N.Achasov O.Albayrak D.J.Ambrose 安芬芬安琪白景芝 R.Baldini Ferroli 班勇 J.Becker J.v.Bennett M.Bertani 边渐鸣 E.Boger O.Bondarenko I.Boyko S.Braun R.A.Briere v.Bytev 蔡浩蔡啸 O.Cakir A.Calcaterra 曹国富 S.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈江川陈玛丽陈申见陈旭荣陈元柏程和平初元萍 D.Cronin-Hennessy 代洪亮代建平 D.Dedovich 邓子艳 A.Denig I.Denysenko M.Destefanis 丁伟民丁勇董燎原董明义杜书先方建房双世 L.Fava 封常青 P.Friedel 傅成栋傅金林 O.Fuks 高原宁耿聪 k.Goetzen 龚文煊 W.Gradl M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭墩郭玉萍韩艳良 F.A.Harris 何康林何苗何振亚 T.Held 衡月昆侯治龙胡深胡海明胡继峰胡涛黄光明黄光顺黄金书黄亮黄性涛黄勇 T.Hussain 姬长胜纪全姬清平季晓斌季筱璐姜丽丽江晓山焦健斌焦铮金大鹏金山景繁凡 N.kalantar-Nayestanaki M.kavatsyuk B.kloss B.kopf M.kornicer W.kuehn 赖蔚 J.S.Lange M.Lara P.Larin M.Leyhe 李春花李澄李翠李德民李飞李刚李海波李家才李康李蕾李培荣李秋菊李卫东李卫国李晓玲李小男李学潜李秀荣李志兵梁昊梁勇飞梁羽铁廖广瑞 D.X.LinLin 刘北江 C.L.Liu 刘春秀刘福虎刘芳刘峰刘宏邦刘汇慧刘怀民刘觉平刘凯刘魁勇刘佩莲刘倩刘树彬刘翔刘玉斌刘振安刘志强刘智青 H.Loehner 娄辛丑鲁公儒吕海江吕军光吕晓睿卢云鹏罗成林罗民兴 T.Luo 罗小兰吕蒙马凤才马海龙马秋梅马斯马天马骁妍 F.E.Maas M.Maggiora Q.A.Malik 冒亚军毛泽普 J.G.Messchendorp 阂建闵天觉 R.E.Mitchell 莫晓虎 H.Moeini C.Morales Morales k.Moriya N.Yu.Muchnoi H.Muramatsu Y.Nefedov I.B.Nikolaev 宁哲 S.Nisar 马鹏欧阳群 S.Pacetti J.W.Park M.Pelizaeus 彭海平 k.Peters 平加伦平荣刚 R.Poling E.Prencipe 祁鸣钱森乔从丰秦丽清秦小帅秦瑶秦中华邱进发 k.H.Rashid C.F.Redmer 荣刚阮向东 A.Sarantsev 邵明沈成平沈肖雁盛华义 M.R.Shepherd 宋维民宋新颖 S.Spataro B.Spruck 孙功星孙俊峰孙胜森孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.Tapan E.H.Thorndike D.Toth M.Ullrich I.Uman G.S.varner 王斌王东王大勇王科王亮亮王灵淑王萌王平王佩良王庆娟王思广王雄飞汪晓莲 Y.D.WangYadi 王贻芳王亚乾王铮王志刚王志宏王至勇魏代会韦江波 P.Weidenkaff 文群刚文硕频 M.Werner U.Wiedner 伍灵慧吴宁吴硕星吴蔚吴智夏力钢夏宇肖振军谢宇广修青磊许国发徐庆君徐庆年徐新平许志蕊薛镇严亮鄢文标闺文成颜永红杨洪勋杨迎杨永栩叶桦叶梅叶铭汉俞伯祥喻纯旭于海旺俞洁晟于帅鹏苑长征n 袁野 A.A.Zafar A.Zallo 臧石磊曾云张丙新张炳云张驰张长春张达华张宏浩章红宇张敬庆张家文张建勇张景芝张丽丽张书华张晓杰张学尧张瑶张银鸿张子平张振宇张正好赵光赵京伟赵雷赵玲赵明刚赵强赵书俊赵天池赵祥虎赵豫斌赵政国 A.Zhemchugov 郑波郑建平郑阳恒钟彬周莉周详周晓康周小蓉朱凯朱科军朱相雷朱莹春朱永生朱自安庄建邹冰松邹佳恒 Institute of High Energy Physics Chinese Academy of Sciences G.I.Budker Institute of Nuclear Physics SB RAS (BINP) Also at the Novosibirsk State University Carnegie Mellon University Pittsburgh University of Rochester Rochester University of Science and Technology of China INFN Laboratori Nazionali di Frascati Peking University Bochum Ruhr-University Indiana University Bloomington University of Minnesota Minneapolis Joint Institute for Nuclear Research Also at the Moscow Institute of Physics and Technology kvI University of Groningen Universitaet Giessen Wuhan University Ankara University Dogol Caddesi Dogus University Nanjing University Lanzhou University Huangshan College Johannes Gutenberg University of Mainz University of Turin INFN Shandong University Liaoning University Zhengzhou University University of Eastern Piedmont Tsinghua University GSI Helmholtzcentre for Heavy Ion Research GmbH GuangXi University University of Chinese Academy of Sciences Nankai university Nanjing Normal University University of Hawaii Central China Normal University Henan Normal University University of the Punjab Helmholtz Institute Mainz Hangzhou Normal University Seoul National University Sun Yat-Sen University Sichuan University Shanxi University Henan University of Science and Technology Also at University of Texas at Dallas Zhejiang University COMSATS Institute of Information Technology INFN and University of Perugia University of Minnesota Also at the PNPI Beihang University Uludag University Guangxi Normal University Hunan University Soochow University China Center of Advanced Science and Technology University of South China

Data sets were collected with the BESⅢ detector at the BEPCⅡ collider at the center-of-mass energy of √s=3.650 Gev during May 2009 and at √s=3.773 Gev from January 2010 to May 2011. By analyzing the large angle Bhabha scattering events, the integrated luminosities of the two data sets are measured to be （44.49±0.02±0.44） pb-1 and （2916.94±0.18±29.17） pb-1, respectively, where the first error is statistical and the second error is systematic.

关键词： Bhabha scattering events integrated luminosity cross section

Notes,outline and divergence times of Basidiomycota

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Fungal Diversity 2019年第6期99卷 105-367页

作者： Mao-Qiang He Rui-Lin Zhao kevin D.Hyde Dominik Begerow Martin kemler Andrey Yurkov Eric H.C.Mckenzie Olivier Raspe Makoto kakishima Santiago Sanchez-Ramırez Else C.vellinga Roy Halling viktor Papp Ivan v.Zmitrovich Bart Buyck Damien Ertz Nalin N.Wijayawardene Bao-kai Cui Nathan Schoutteten Xin-Zhan Liu Tai-Hui Li Yi-Jian Yao Xin-Yu Zhu An-Qi Liu Guo-Jie Li Ming-Zhe Zhang Zhi-Lin Ling Bin Cao vladimir Antonin Teun Boekhout Bianca Denise Barbosa da Silva Eske De Crop Cony Decock Balint Dima Arun kumar Dutta Jack W.Fell Jozsef Geml Masoomeh Ghobad-Nejhad Admir J.Giachini Tatiana B.Gibertoni Sergio P.Gorjon Danny Haelewaters Shuang-Hui He Brendan P.Hodkinson Egon Horak Tamotsu Hoshino Alfredo Justo Young Woon Lim Nelson Menolli Jr Armin Mesic Jean-Marc Moncalvo Gregory M.Mueller La szlo G.Nagy RHenrik Nilsson Machiel Noordeloos Jorinde Nuytinck Takamichi Orihara Cheewangkoon Ratchadawan Mario Rajchenberg Alexandre G.S.Silva-Filho Marcelo Aloisio Sulzbacher Zdenko Tkalcec Ricardo valenzuela Annemieke verbeken Alfredo vizzini Felipe Wartchow Tie-Zheng Wei Michael WeiB Chang-Lin Zhao Paul M.kirk State key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101People’s Republic of China Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand College of Life Sciences University of Chinese Academy of SciencesHuairou DistrictBeijing 100408People’s Republic of China Ruhr-Universitat Bochum AG GeobotanikND03UniversitatsstraBe 15044801 BochumGermany Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures InhoffenstraBe 7B38124 BrunswickGermany Manaaki Whenua-Landcare Research Private Bag 92170AucklandNew Zealand Research Department Meise Botanic GardenNieuwelaan 381860 MeiseBelgium Service General de l'Enseignement superieur et de la Recherche scientifique Federation Wallonie-BruxellesLavallee 11080 BrusselsBelgium University of Tsukuba TsukubaIbaraki 305-8572Japan Department of Ecology and Evolutionary Biology University of Toronto25 Willcocks St.TorontoON M5S 3B2Canada Berkeley USA Institute of Systematic Botany The New York Botanical GardenBronxNY 10458-5126USA Department of Botany Szent Istvan University1518 BudapestHungary komarov Botanical Institute Russian Academy of SciencesProfessor Popov st.2Saint PetersburgRussia 197376 Institut pour Systematique Ecologie Biodiversite(ISYEB UMR 7205) Sorbonne universiteMuseum National d’Histoire Naturelle CP 39CNRSDepartement Origines et Evolution12 Rue Buffon75005 ParisFrance Institute of Microbiology Beijing Forestry UniversityBeijing 100083People’s Republic of China Department of Biology Research Group MycologyGhent UniversityK.L.Ledeganckstraat 359000 GhentBelgium State key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Institute of MicrobiologyGuangzhou 510070People’s Republic of China Department of Botany Moravian Mu

The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the *** present work provides an overview of all validly published,currently used basidiomycete genera to date in a single *** outline of all genera of Basidiomycota is provided,which includes 1928 currently used genera names,with 1263 synonyms,which are distributed in 241 families,68 orders,18 classes and four *** provide brief notes for each accepted genus including information on classification,number of accepted species,type species,life mode,habitat,distribution,and sequence ***,three phylogenetic analyses with combined LSU,SSU,5.8s,rpb1,rpb2,and ef1 datasets for the subphyla Agaricomycotina,Pucciniomycotina and Ustilaginomycotina are conducted,*** time estimates are provided to the family level with 632 species from 62 orders,168 families and 605 *** study indicates that the divergence times of the subphyla in Basidiomycota are 406-430 Mya,classes are 211-383 Mya,and orders are 99-323 Mya,which are largely consistent with previous *** this study,all phylogenetically supported families were dated,with the families of Agaricomycotina diverging from 27-178 Mya,Pucciniomycotina from 85-222 Mya,and Ustilaginomycotina from 79-177 *** times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the Basidiomycota taxonomic system,and also provide a better understanding of their phylogeny and evolution.

关键词： Classification Molecular clock Fungi Systematics Taxonomy

新一代有机硅整理剂Magnasoft SilQ~在棉织物上吸附沉淀行为的研究(一)

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国际纺织导报 2012年第5期40卷 47-47,50,51,54,82页

作者： M. Er-Rafik A. L. Mohamed M. Mller k. Spyropoulos R. Wagner DWI anderRWTHAachene.V.andInstituteofTechnicalMacromolecularChemistry亚琛工业大学(德国) Textile Research Division National Research Centre(埃及) Momentive Performance Materials公司(德国)

季铵基团改性硅油,又称季铵硅油,近年来被作为柔软剂应用在纺织行业中。最近,迈图高新材料公司开发和推出了一款全新的持久型亲水季铵硅油——Magnasoft SilQ。就Magnasoft SilQ在棉织物吸附过程的动力学做了深入研究。先将Magnasoft ... 详细信息

季铵基团改性硅油,又称季铵硅油,近年来被作为柔软剂应用在纺织行业中。最近,迈图高新材料公司开发和推出了一款全新的持久型亲水季铵硅油——Magnasoft SilQ。就Magnasoft SilQ在棉织物吸附过程的动力学做了深入研究。先将Magnasoft SilQ用荧光标记,再用Uv/vIS(紫外可见光谱)和ATR-IR(傅里叶变换衰减全反射红外光谱)等表征手段,对在不同温度和不同浓度下Magnasoft SilQ在棉织物上的吸附动力学进行了研究,并在此基础上建立了吸附模型。此外,借助荧光显微镜、EDX(X光能谱)、拉曼电镜等仪器,对Magnasoft SilQ在棉织物表面以及横截面的分布做了分析。最后,对Magnasoft SilQ被阴离子洗涤剂洗涤时的解吸附过程的动力学做了研究。

关键词：织物整理剂吸附动力学解吸附动力学有机硅分布 Magnasoft SilQ

In silico evidence of Remdesivir action in blood coagulation cascade modulation in COvID-19 treatment

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World Journal of Biological Chemistry 2023年第4期14卷 72-83页

作者： Luis Gustavo Pagliarin Lucca Miketen de Oliveira valentina Nunes Fontoura dos Anjos Cristiano de Bem Torquato de Souza Gabrielle Caroline Peiter Cinthia Façanha Wendel Anderson Dillmann Groto Fabrício Freire de Melo kádima Nayara Teixeira Campus Toledo Universidade Federal do ParanáToledo 85.919-899ParanáBrazil Programa Multicêntrico de Pós-graduação em Bioquímica e Biologia Molecular-Setor Palotina Universidade Federal do ParanáPalotina 85.950-000ParanáBrazil Instituto Multidisciplinar em Saúde-Campus Anísio Teixeira Universidade Federal da BahiaVitória da Conquista 45.029-094BahiaBrazil

BACkGROUND Coronavirus disease 2019(COvID-19)has demonstrated several clinical manifestations which include not only respiratory system issues but also liver,kidney,and other organ *** of these abnormalities is coagulopathies,including thrombosis and disseminated intravascular *** of this,the administration of low molecular weight heparin is required for patients that need to be *** addition,Remdesivir is an antiviral that was used against Middle East Acute Respiratory Syndrome,Ebola,Acute Respiratory Syndrome,and other diseases,showing satisfactory results on ***,there is evidence suggesting that this medication can provide a better prognosis for patients with *** To investigate in silico the interaction between Remdesivir and clotting factors,pursuing a possibility of using it as *** In this in silico study,the 3D structures of angiotensin-converting enzyme 2(ACE2),Factor I(fibrinogen),Factor II(prothrombin),Factor III(thromboplastin),Factor v(proaccelerin),Factor vII(proconvertin),Factor vIII(antihemophilic factor A),Factor IX(antihemophilic factor B),Factor X(Stuart-Prower factor),and Factor XI(precursor of thromboplastin(these structures are technically called receptors)were selected from the Protein Data *** structures of the antivirals Remdesivir and Osetalmivir(these structures are called ligands)were selected from the PubChem database,while the structure of Atazanavir was selected from the ZINC *** software AutoDock Tools(ADT)was used to prepare the receptors for molecular ***,peptides,water molecules,and other ones were removed from each ligand,and then,hydrogen atoms were added to the *** grid box was delimited and calculated using the same software ADT.A physiological environment with pH 7.4 is needed to make the ligands interact with the receptors,and still the software Marvin sketch®(ChemAxon®)was used to forecast the protonation *** perform m

关键词： Clotting factors Coagulating blood cascade COvID-19 treatment Remdesivir SARS-Cov-2

氯吡格雷可减少经导管封堵永久卵园孔和房间隔缺损后有先兆的偏头痛发生

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世界核心医学期刊文摘（心脏病学分册） 2006年第1期2卷 52-52页

作者： Wilmshurst P. T. Nightingale S. Walsh k. P. Morrison W. L. 代喆 Dr.Royal Shrewsbury Hospital Shrewsbury SY3 8XQ United Kingdom

Objective: To report the clinical events leading to alteration of an anticoagulation regimen for patients undergoing transcatheter closure of an atrial shunt and how this affected migraine symptoms after the closure procedure. Method: Audit of a change of anticoagulant regimen. Results: In the first few weeks after a closure procedure migraine frequency and severity increased despite treatment with aspirin for six months in 71 patients. Severe attacks of migraine with aura, including status migrainosus, in the first few weeks after transcatheter closure were terminated by addition of clopidogrel to aspirin treatment. Therefore, the anticoagulant regimen was changed with addition of clopidogrel for the first month after the closure procedure(90 procedures in 89 patients). Fewer patients had migraine with aura in the first month after transcatheter closure when taking the combination of clopidogrel and aspirin compared with aspirin alone(11 of 90(12.2%) v 30 of 71(42.3%), pvere and more frequent in patients taking aspirin alone. Conclusion: The combination of clopidogrel for four weeks and aspirin for six months is superior to aspirin alone for six months for preventing migraine with aura after transcatheter closure of an atrial shunt. This beneficial effect of a powerful inhibitor of platelet aggregation suggests that platelets may have a role in pathogenesis of migraine. This may be because of an effect on serotonin stores. Whether clopidogrel has a role in treatment of migraine in other clinical situations requires investigation.

关键词：偏头痛持续状态经导管封堵氯吡格雷房间隔缺损先兆药物治疗方案封堵术后永久术后抗凝头痛症状

The Faces of Fungi database:fungal names linked with morphology,phylogeny and human impacts

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Fungal Diversity 2015年第5期74卷 3-18页

作者： Subashini C.Jayasiri kevin D.Hyde Hiran A.Ariyawansa Jayarama Bhat Bart Buyck Lei Cai Yu-Cheng Dai kamel A.Abd-Elsalam Damien Ertz Iman Hidayat Rajesh Jeewon E.B.Gareth Jones Ali H.Bahkali Samantha C.karunarathna Jian-kui Liu J.Jennifer Luangsa-ard H.Thorsten Lumbsch Sajeewa S.N.Maharachchikumbura Eric H.C.Mckenzie Jean-Marc Moncalvo Masoomeh Ghobad-Nejhad Henrik Nilsson ka-Lai Pang Olinto L.Pereira Alan J.L.Phillips Olivier Raspé Adam W.Rollins Andrea I.Romero Javier Etayo Faruk Selçuk Steven L.Stephenson Satinee Suetrong Joanne E.Taylor Clement k.M.Tsui Alfredo vizzini Mohamed A.Abdel-Wahab Ting-Chi Wen Saranyaphat Boonmee Dong Qin Dai Dinushani A.Daranagama Asha J.Dissanayake Anusha H.Ekanayaka S.C.Fryar Sinang Hongsanan Ruvishika S.Jayawardena Wen-Jing Li Rekhani H.Perera R.Phookamsak Nimali Ide Silva kasun M.T.hambugala Qing Tian Nalin N.Wijayawardene Rui-Lin Zhao Qi Zhao Ji-Chuan kang Itthayakorn Promputtha Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agro forestry Centre East and Central Asia Office 132 Lanhei RoadKunming 650201China Botany and Microbiology Department College of ScienceKing Saud UniversityRiyadh 1145Saudi Arabia Guizhou key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha403108 GoaIndia Department of Botany Goa UniversityGoa 403206India Muséum National d’Histoire Naturelle Département Systématique et EvolutionCP 39ISYEBUMR 7205 CNRS MNHN UPMC EPHE12 Rue BuffonF-75005 ParisFrance State key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesWest Beicheng RdBeijingChina Institute of Microbiology Beijing Forestry UniversityPO Box 61Beijing 100083China Plant Pathology Research Institute Agricultural Research Center(ARC)12619 GizaEgypt Botanic Garden Meise Department Bryophytes-Thallophytes(BT)Nieuwelaan 38B-1860 MeiseBelgium Fédération Wallonie-Bruxelles Direction Générale de l’Enseignement non obligatoire et de la Recherche scientifiqueRue A.Lavallée 11080 BruxellesBelgium Microbiology Division Research Center for BiologyIndonesian Institute of Sciences(LIPI)Jl.Raya Jakarta-Bogor KM 46Cibinong 16911West JavaIndonesia Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Science&Education The Field Museum1400 S.Lake Shore DriveChicagoIL 60605USA Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand Department of Natural History Royal Ontario Museumand Department of Ecology and Evolutionary BiologyUniversity of Toronto100 Queen’s ParkTorontoON M5S2C6Canada Department of Biotechnology Iranian Research Organiza

Taxonomic names are key links between various databases that store information on different *** global fungal nomenclural and taxonomic databases(notably Index Fungorum,Species Fungorum and MycoBank)can be sourced to find taxonomic details about fungi,while DNA sequence data can be sourced from NCBI,EBI and UNITE *** the sequence data may be linked to a name,the quality of the metadata is variable and generally there is no corresponding link to images,descriptions or herbarium *** is generally no way to establish the accuracy of the names in these genomic databases,other than whether the submission is from a reputable *** tackle this problem,a new database(FacesofFungi),accessible at ***(FoF)has been *** fungal database allows deposition of taxonomic data,phenotypic details and other useful data,which will enhance our current taxonomic understanding and ultimately enable mycologists to gain better and updated insights into the current fungal classification *** addition,the database will also allow access to comprehensive metadata including descriptions of voucher and type *** database is user-friendly,providing links and easy access between taxonomic ranks,with the classification system based primarily on molecular data(from the literature and via updated web-based phylogenetic trees),and to a lesser extent on morphological data when molecular data are *** FoF species are not only linked to the closest phylogenetic representatives,but also relevant data is provided,wherever available,on various applied aspects,such as ecological,industrial,quarantine and chemical *** data include the three main fungal groups(Ascomycota,Basidiomycota,Basal fungi)and fungus-like *** FoF webpage is an output funded by the Mushroom Research Foundation which is an NGO with seven directors with mycological *** webpage has 76 curators,and with the help of these s

关键词： Classification Database Faces of Fungi Fungi Phylogeny Taxonomy