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Accuracy and Consistency of Respiratory Inductive Plethysmography for Overnight Tidal Volume Measurement

Journal of Huazhong University of Science and Technology(Medical Sciences) 2001年第1期21卷 35-37,58页

作者：张劲农 eric W Ruch konrad e bloch Respiratory Disease Research Laboratory Xiehe Hospital Tongji Medical College Huazhong University of Science and Technology Abteilung Pneumologie Unisipital Zuerich

To validate the accuracy and consistency of respiratory inductive plethysmography (RIP) in measuring tidal volume after an overnight sleep, tidal volumes of 18 patients with suspected sleep disordered breathing and 8 normal volunteers were measured simultaneously with RIP (V TRIP ) and with an ultrasonic airflow meter (V TUFM ) before and after an unstrained overnight sleep on supine and lateral decubitus. The bias of the V TRIP was expressed as (V TRIP V TUFM )/ V TUFM ·100 %, limits of agreement between V TRIP and V TUFM was measured by averaged bias ±2 s . Results showed that in normal subjects, the bias of RIP before and after overnight sleep was precise and consistent in both supine (0.7 % and -1.6 %) and lateral decubitus (3.7 % and -0.56 %). In these patients, the bias of RIP before and after sleep in supine also remained small (1.9 % and 1.7 %), but it became larger in lateral decubitus (24.5 % and 20.4 %) and 11.5 % exceeded the limits of agreement observed in the evening. The patients′ body mass indices (BMI) were higher than those of normal subjects (median 34.2 vs. 27.8 kg/m 2). Pooled data showed that the bias of V TRIP in the morning on lateral decubitus but not on supine was correlated to BMI (Spearman R=0.32, n =52, P =0.02). Thus, we were led to conclude that the accuracy of V TRIP overnight was precise and consistent in normal subjects, but the deviation of V TRIP measured on lateral decubitus in patients especially in those with excessive obesity was greater, thus, the method should not be used for quantitative determination.

关键词： sleep study respiratory inductive plethysmography (RIP) tidal volume

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Sleep apnea in Tibetans and Han long-term high altitude residents

Sleep apnea in Tibetans and Han long-term high altitude resi...

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第五届中国西部睡眠医学大会暨重庆市心理卫生协会睡眠医学学术年会

作者： Lu Tan Taomei Li Michael Furian Xiaofang Xue Rong Ren Junying Zhou Ye Zhang Jiaming He Silvia Ulrich konrad e.bloch Xiangdong Tang Sleep Medicine Center West China HospitalSichuan University Sleep Disorders Center Dept.of Respiratory MedicineUniversity Hospital Zurich Department of Cardiology Diqing Tibetan Autonomous Prefectural People's Hospital

Introduction Obstructive sleep apnea(OSA) is associated with adverse health outcomes in *** propensity to OSA may be modified by ethnic and environmental *** compared the prevalence of sleep apnea between Tibetans and Hanlong-term residents at high ***86 consecutive long-term residents(>5 y) of Shangri-La,3200m,China,referred for evaluation of

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Sleep apnea in Tibetans and Han long-term high altitude residents

Sleep apnea in Tibetans and Han long-term high altitude resi...

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中国睡眠研究会第十届全国学术年会

＜正＞Introduction Obstructive sleep apnea （OSA） is associated with adverse health outcomes in lowlanders. The propensity to OSA may be modified by ethnic and environmental influences. We compared the prevalence of ...

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Light correcting light with nonlinear optics

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Advanced Photonics 2024年第2期6卷 41-49页

作者： Sachleen Singh Bereneice Sephton Wagner Tavares Buono Vincenzo D'Ambrosio Thomas konrad Andrew Forbes University of the Witwatersrand School of Physics Università degli studi di Napoli “Federico Ⅱ” Dipartimento di Fisica “E.Pancini” University of Kwa Zulu-Natal School of Chemistry and Physics

Structured light, where complex optical fields are tailored in all their degrees of freedom, has become highly topical of late, advanced by a sophisticated toolkit comprising both linear and nonlinear *** undesired structure from light is far less developed, leveraging mostly on inverting the distortion,e.g., with adaptive optics or the inverse transmission matrix of a complex channel, both requiring that the distortion be fully characterized through appropriate measurement. We show that distortions in spatially structured light can be corrected through difference-frequency generation in a nonlinear crystal without any need for the distortion to be known. We demonstrate the versatility of our approach using a wide range of aberrations and structured light modes, including higher-order orbital angular momentum(OAM) beams,showing excellent recovery of the original undistorted field. To highlight the efficacy of this process, we deploy the system in a prepare-and-measure communications link with OAM, showing minimal cross talk even when the transmission channel is highly aberrated, and outline how the approach could be extended to alternative experimental modalities and nonlinear processes. Our demonstration of light-correcting light without the need for measurement opens an approach to measurement-free error correction for classical and quantum structured light, with direct applications in imaging, sensing, and communication.

关键词： phase conjugation aberration correction orbital angular momentum nonlinear optics

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Rare dentin defects:Understanding the pathophysiological mechanisms of COLXVA1 mutations

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Genes & Diseases 2024年第5期11卷 1-5页

作者： Isaac Maximiliano Bugueno Tristan Rey Alexandra Jimenez-Armijo Marzena Kawczynski Naji Kharouf Marie-Cecile Maniere Yann Herault Agnes bloch-Zupan Virginie HaushalterLaugel Institute of Genetics and Molecular and Cellular Biology(IGBMC) CNRS-UMR7104INSERM U1258Universitede StrasbourgIllkirch 67400France Faculty of Dentistry Universitede StrasbourgStrasbourg 67000France Institute of Advanced Studies(USIAS) Universitede StrasbourgStrasbourg 67045France Reference Center for Rare Oral and Dental Diseases(CRMR-O-Rares) Oral Medicine and Surgery DepartmentHopitaux Universitaires de Strasbourg(HUS)Strasbourg 67000France Rare Diseases Health Network“TeTe COU”&european Reference Network eRN CRANIO Strasbourg 67000France “Institut de Genetique Medicale d’Alsace” Laboratory of Genetic DiagnosticHopitaux Universitaires de Strasbourg(HUS)Strasbourg 67000France Biomaterials and Bioengineering Laboratory Inserm UMR_S 1121Strasbourg 67000France Orofacial Development and Regeneration Faculty of MedicineInstitute of Oral BiologyCentre of Dental MedicineUniversity of ZurichZurich 8032Switzerland

Dentin is a mineralized tissue with a chemical composition similar to bone but with a higher mineralized density and *** constitutes the central structure of the tooth between the internal pulp and external enamel toward the oral cavity or cementum toward the underlying *** dentin defects occur in a variety of rare genetic *** can manifest as“isolated”occurrences such as in dentinogenesis imperfecta(DI)or dentin dysplasia(DD)or can be associated with other symptoms in diseases such as osteogenesis imperfecta,Goldblatt syndrome,microcephalic osteodysplastic primordial dwarfism type Ⅱ,among others.

关键词： diseases den rigidity

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Gap formation around Ω_e/2 and generation of low-band whistler waves by Landau-resonant electrons in the magnetosphere: Predictions from dispersion theory

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earth and Planetary Physics 2020年第2期4卷 138-150页

作者： konrad Sauer Klaus Baumgartel Richard Sydora Max-Planck-Institute for Solar System Research GöttingenGermany(up to 2005 Leibnitz-Institut für Astrophysik(AIP) PotsdamGermany(up to 2008 Institute for Geophysical Research University of AlbertaEdmontonCanada

In this paper we show that two significant phenomena of magnetospheric chorus emission can be explained by the participation of beam-like electron structures,created by Landau-resonant interaction with growing oblique whistler *** first concerns the widely observed spectral gap near half the electron cyclotron frequency Ωe;the second is related to the observation of very obliquely propagating lower-band waves that cannot be directly generated by temperature *** the gap,kinetic dispersion theory reveals that interference of the beam-related cyclotron mode ω~Ωe-kVb with the conventional whistler mode leads to mode splitting and the appearance of a ’forbidden’ area in the ω-k *** the beam velocity appears as an essential *** is directly related to the phase velocity of the most unstable whistler wave mode,which is close to VAe/2 for sufficiently hot electrons(VAe is the electron Alfven velocity).To clarify the second point,we show that Landau-resonant beams with Vb Vbe/2,which arise in cold plasmas from unstable upper-band waves,are able to generate lower-band whistler mode waves at very oblique propagation(θ≥60°).Our studies demonstrate the important role of Landau-resonant electrons in nonlinear whistler wave generation in the magnetosphere.

关键词： important role play Landau-resonant electrons modification of the electron distribution function gap formation at half the electron cyclotron frequency

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High-performance oxygen permeation membranes:Cobalt-free Ba_(0.975)La_(0.025)Fe_(1-x)Cu_(x)O_(3)-δceramics

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Journal of Materiomics 2019年第2期5卷 264-272页

作者： Zilu Liu Kui Li Hailei Zhao konrad Swierczek School of Materials Science and engineering University of Science and Technology BeijingBeijing 100083China Beijing Municipal Key Lab for Advanced energy Materials and Technologies Beijing 100083China AGH University of Science and Technology Faculty of Energy and Fuelsal.A.Mickiewicza 3030-059 KrakowPoland AGH Centre of energy AGH University of Science and Technologyul.Czarnowiejska 3630-054 KrakowPoland

A new group of cobalt-free perovskite oxides,Ba_(0.975)La_(0.025)Fe_(1-x)Cu_(x)O_(3-δ)(BLFC,x=0.05-0.15),was designed,characterized and applied as oxygen permeation *** was found that BLFC oxides with Cu doping range of 0.075-0.15 maintain cubic perovskite phase in a wide range of *** Cu introduced at the B-site results in a gradual increase of the electrical conductivity,which is attributed to the denser overlapping of electron clouds of CueO *** increasing Cu content,the oxygen vacancy concentration increases and the oxygen ion migration energy decreases,leading to the highest oxygen permeation flux of 1.59 mL cm^(-2)min^(-1)recorded for Ba_(0.975)La_(0.025)Fe_(0.9)Cu_(0.1)O_(3-δ)1mm thick membrane at 950℃.However,the oxygen permeability decreases with further Cu doping,which may be correspond to a presence of defect ***_(0.975)La_(0.025)Fe_(0.9)Cu_(0.10)O_(3-δ)membrane with 0.7mm thickness delivers stable oxygen permeation flux of 1.57 mL cm^(-2)min^(-1)for 200 h at 900℃.All of the obtained results indicate that the developed BLFC with optimized Cu content(i.e.x=0.1)is a very promising material for usage in oxygen separation applications.

关键词： Perovskite Oxygen permeability Structure stability Oxygen ion migration

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Natural variation in social conditions affects male mate choosiness in the amphipod Gammarus roeselii

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Current Zoology 2022年第4期68卷 459-467页

作者： konrad Lipkowski Sophie Steigerwald Lisa M Schulte Carolin Sommer-Trembo Jonas Jourdan Department of Wildlife/Zoo-Animal-Biology and Systematics Institute for EcologyEvolution and Diversity Goethe University FrankfurtMaxvon-Laue-Straße 13Frankfurt am MainD-60438Germany Department of environmental Science Stockholm UniversitySvante Arrheniusväg 8StockholmSE-11418Sweden Zoological Institute University of BaselVesalgasse 1BaselCH-4051Switzerland Department of Aquatic ecotoxicology Institute for EcologyEvolution and DiversityGoethe University Frankfurt am MainFrankfurt am MainGermany

The extent of male mate choosiness is driven by a trade-off between various environmental factors associated with the costs of mate acquisition,quality assessment and opportunity *** knowledge about natural variation in male mate choosiness across different populations of the same species,however,remains *** this study,we compared male mate choosiness across 10 natural populations of the freshwater amphipod Gammarus roeselii(Gervais 1835),a species with overall high male mating investments,and evaluated the relative influence of population density and sex ratio(both affecting mate availability)on male mate *** investigated amplexus establishment after separating mating pairs and presenting focal males with a novel,size-matched female from the same *** analysis revealed considerable effects of sex ratio and(to a lesser extent)population density on time until amplexus establishment(choosiness).Male amphipods are able to perceive variable social conditions(e.g.,sex ratio)and modify their mating strategy accordingly:We found choosiness to be reduced in increasingly male-biased populations,whereas selectivity increases when sex ratio becomes female *** this,our study expands our limited knowledge on natural variations in male mate choosiness and illustrates the importance of sex ratio(i.e.,level of competition)for male mating decisions in natural *** for variation in sex ratios,therefore,allows envisioning a distinctive variation of choosiness in natural populations and highlights the importance of considering social background information in future behavioral studies.

关键词： amplexus Crustacea local adaptation mate choice population density sex ratio

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MODeLING COMMeRCIAL PROCeSSeS AND CUSTOMeR BeHAVIORS TO eSTIMATe THe DIFFUSION RATe OF NeW PRODUCTS

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Journal of Systems Science and Systems engineering 2005年第4期14卷 436-453页

作者： Alain bloch Daniel KROB Ada Suk-Fung NG Chaire Action Commerciale et Distribution Conservatoire National des Arts et Métiers 40 rue des Je■neurs 75002 Paris France Laboratoire d'Informatique de l'ecole Polytechnique Ecole Polytechnique & CNRS 91128 Palaiseau Cedex France Department of Transportation & Logistics Malaysia University of Science and Technology Kelana Square Kelana Jaya 47301 Petaling Jaya Selangor Malaysia

This paper presents a generic mathematical model for depicting the diffusion of an innovative product on a given market. Our approach relies on a probabilistic modeling of each customer behavior with respect to the commercial process which is used to promote such a product. We introduce in particular the concept of coherent market that corresponds to a market which can be analyzed in a uniform way within our model. This last notion allows us to recover the classical empirical results that were discovered and widely studied by e.M. Rogers and his school. We explain finally how to use our approach as a support for analytic predictive marketing.

关键词： Analytic marketing coherent market commercial process customer behavior diffusion of innovations Markovian model probabilistic modeling waiting time

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Does endurance training improve red blood cell aging and hemorheology in moderate-trained healthy individuals?

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Journal of Sport and Health Science 2020年第6期9卷 595-603页

作者： Daniel A.Bizjak Fabian Tomschi Gunnar Bales elie Nader Marc Romana Philippe Connes Wilhelm bloch Marijke Grau Department of Molecular and Cellular Sports Medicine German Sport University CologneCologne 50933Germany Laboratoire LIBM eA7424-equipe“Biologie Vasculaire et du Globule Rouge” UniversitéClaude Bernard Lyon 1Villeurbanne 69100France Laboratoire d’excellence du Globule Rouge GR-ex Paris 75015France Universitédes Antilles InsermUnitéBiologie Intégrée du Globule RougeCHU de PointeàPitrePointe_a PitreGuadeloupe 97157France Institut Universitaire de France Paris 75231France The German Research Centre of elite Sport German Sport University CologneCologne 50933Germany

Objective:To examine the impact of a 6-week endurance training on red blood cell(RBC)aging and deformability of healthy participants to detect possible improved hemorheological and performance-related ***:A total of 31 participants(17 females and 14 males)performed a 6-week moderate training protocol(three 1-h running sessions per week at 70%of maximal heart rate).Blood was sampled before and after the *** from each participant were fractioned according to density and age into 4 RBC *** were examined for changes of RBC properties,including aging distribution,RBC deformability,RBC microparticles,and phosphatidylserine *** and plasma nitrite levels were measured as indicators of nitric oxide ***:Aerobic performance,peak oxygen consumption,ventilatory thresholds,velocity at the aerobic-anaerobic threshold,and lactate at exhaustion improved after *** relative amount of both young RBCs and old RBCs increased,and the amount of the main RBC fraction *** externalization and RBC-derived microparticles *** deformability expressed as shear stress required to achieve half-maximum deformation to theoretical maximal elongation index at infinite shear stress improved in unfractioned RBCs(pe decreased in total(p=0.001),young(ped RBCs and in plasma(p=0.002),but not in very old ***:These results indicate that non-endurance-trained healthy participants benefit from a regular moderate running training program because performance-related parameters improve and a younger RBC population with improved RBC properties is induced,which might support oxygen supply in the microcirculation.

关键词： Cellular adaptation Hemorheology Nitric oxide Performance RBC physiology and aging

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