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Journal of Environmental Sciences 2014年第8期26卷 1689-1697页

作者： deyong kong Bin Liang Duu-Jong Lee Aijie Wang Nanqi Ren State Key Laboratory of Urban Water Resource and Environment School of Municipal and Environmental EngineeringHarbin Institute of Technology Key laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of Sciences

Exposure to chloramphenicol（CAP）,a chlorinated nitroaromatic antibiotic,can induce CAP-resistant bacteria/genes in diverse environments. A biocathode bioelectrochemical system（BES） was applied to reduce CAP under switched operational *** switching from 25 to 10°C,the CAP reduction rate（kCAP） and the maximum amount of the dechlorinated reduced amine product（AMCl,with no antibacterial activity） by the biocathode communities were both markedly decreased. The acetate and ethanol yield from cathodophilic microbial glucose fermentation（with release of electrons） was also reduced. Formation of the product AMCl was enhanced by the biocathode dechloridation reaction compared with that produced from pure electrochemical or microbial dechloridation processes. The electrochemical and morphological analyses of cathode biofilms demonstrated that some cathodophilic microbes could adapt to low temperature and play a key role in CAP degradation. The resilient biocathode BES has a potential for the treatment of CAP-containing wastewater in temperature fluctuating environments.

关键词： Chloramphenicol degradation Biocathode Dechloridation Temperature switchover

Anaerobic biodegradation of trimethoprim with sulfate as an electron acceptor

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Frontiers of Environmental Science & Engineering 2019年第6期13卷 59-68页

作者： Bin Liang deyong kong Mengyuan Qi Hui Yun Zhiling Li Ke Shi E Chen Alisa SVangnai Aijie Wang Shenyang Academy of Environmental Sciences Shenyang 110167China Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life ScienceLanzhou UniversityLanzhou 730000China The Environmental Monitoring Center of Gansu Province Lanzhou 730020China Department of Biochemistry Faculty of ScienceChulalongkorn UniversityBangkok 10330Thailand Center of Excellence on Hazardous Substance Management(HSM) Chulalongkorn UniversityBangkok 10330Thailand

Trimethoprim(TMP)is an antibiotic frequently detected in various *** are the main drivers of emerging antibiotic contaminant degradation in the ***,the feasibility and stability of the anaerobic biodegradation of TMP with sulfate as an electron acceptor remain poorly ***,TMP-degrading microbial consortia were successfully enriched from municipal activated sludge(AS)and river sediment(RS)as the initial *** acclimated consortia were capable of transforming TMP through demethylation,and the hydroxyl-substituted demethylated product(4-desmethyl-TMP)was further *** biodegradation ofTMP followed a 3-parameter sigmoid kinetic *** potential degraders(Acetobacterium,Desulfovibrio,Desulfbbulbus,and unidentified Peptococcaceae)and fermenters(Lentimicrobium and Petrimonas)were significantly enriched in the acclimated *** AS-and RS-acclimated TMP-degrading consortia had similar core *** anaerobic biodegradation ofTMP could be coupled with sulfate respiration,which gives new insights into the antibiotic fate in real environments and provides a new route for the bioremediation of antibiotic-contaminated environments.

关键词： Trimethoprim(TMP)biodegradation Demethylation Sulfate reduction Core microbiome Antibiotic fate

Discussion on the teaching method of foreign language translation course

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校园英语 2016年第36期 45-46页

作者： kong deyong Public English Department Henan University

This paper discusses the characteristics of foreign advanced teaching material "Beyond the Target", and fully exploit the use of this set of textbooks in teaching on students’ learning strategy training practice.

关键词： "beyond the target" the cultivation of learning strategies

An Attempt to Date the Salt-mounds in the Lop Nor Playa

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Acta Geologica Sinica(English Edition) 2014年第S1期88卷 231-232页

作者： MA Lichun TANG Qingfeng ZHANG Qi kong deyong MLR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesCAGS Beijing Centre for Physical & Chemical Analysis

1 Introduction The Lop Nor playa,located in the eastern end of the Tarim Basin,capped with a thick salt crust covering an area of approximately 5,500 km2(Ma 2007)that closely resembles a"Great Ear"in satellite *** the... 详细信息

关键词： An Attempt to Date the Salt-mounds in the Lop Nor Playa

Regulatory Effect of JAK2/STAT3 on the Immune Function of Endotoxin-tolerant Dendritic Cells and its Involvement in Acute Liver Failure

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Journal of Clinical and Translational Hepatology 2022年第5期10卷 879-890页

作者： Yukai Chen Chaochen Hou Naibin Yang Yanyan Yang Youran Chen deyong kong Yuchun Jiang Minghao Lin Sijie Zheng Shanshan Li Mingqin Lu Ningbo Puji Hospital NingboZhejiangChina Department of Infectious Diseases The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Infectious Diseases Ningbo First HospitalNingboZhejiangChina

Background and Aims:Acute liver failure(ALF)is a potentially fatal clinical syndrome with no effective *** study aimed to explore the role of Janus kinase 2/signal transducer and activator of transcription 3(JAK2/STAT3)pathway in modulating the phenotype and immune function of endotoxin-tolerant dendritic cells(ETDCs).In addition,we explored the use of EDTCs in an experimental model of ALF and investigated the associated ***:In the in vitro experiment,ETDCs were transfected with adenovirus to induce SOCS1^(+/+)ETDCs and SOCS1^(−/−)***,costimulatory molecules and mixed lymphocyte reaction were *** mice were randomly divided into normal control,ALF,ALF+mock-ETDCs,ALF+SOCS1^(+/+)ETDCs,ALF+AG490,and ALF+AG490+SOCS1^(+/+)ETDCs *** examined the therapeutic effect of adoptive cellular immunotherapy by tail-vein injection of target ETDCs 12 h before ALF ***490,a JAK2/STAT3 inhibitor,was used in the in vivo experiment to further explore the protective mechanism of SOCS1^(+/+)***:Compared with control ETDCs,SOCS1^(+/+)ETDCs had lower expression of costimulatory molecules,weaker allostimulatory ability,lower levels of IL-6 and TNF-αexpression and higher IL-10 ***1^(−/−)ETDCs showed the opposite *** the in vivo experiments,the ALF+SOCS1^(+/+)ETDCs and ALF+AG490+SOCS1^(+/+)ETDCs groups showed less pathological damage and suppressed activation of JAK2/STAT3 *** changes were more pronounced in the ALF+AG490+SOCS1^(+/+)ETDCs *** of SOCS1^(+/+)ETDCs had a protective effect against ALF possibly via inhibition of JAK2 and STAT3 ***:The SOCS1 gene had an important role in induction of endotoxin ***1^(+/+)ETDCs alleviated lipopolysaccharide/D-galactosamine-induced ALF by downregulating the JAK2/STAT3 signaling pathway.

关键词： Liver failure Acute Janus kinase 2/signal transducers and activators of transcription 3(JAK2/STAT3) Endotoxin tolerance Dendritic cells

Water Absorption Capcapability and Moisture Content Seasonal Changing of Salt-Crust in Lop Nur Dry Lake

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Acta Geologica Sinica(English Edition) 2014年第S1期88卷 183-184页

作者： kong deyong LI Baoguo MA Lichun JIANG Ping'an WU Hongqi LIU Hongpeng College of Resources and Environment China Agricultural University Institute of Mineral Resources Chinese Academy of Geological Sciences College of Grassland and Environment Science Xinjiang Agricultural University

The Lop Nur dry salt lake,Xinjiang province,is charactered by typical physiognomy salt-crust,located *** and *** thickness of salt-crust is about from 20 cm to 100 cm,and

关键词： Lop Nur Dry Lake Salt-Crust Moisture Content Water Absorption Capcapability

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新时代农民获得感与乡村制度体系供给

中共天津市委党校学报 2020年第6期22卷 56-65页

作者：孔德永天津师范大学马克思主义学院天津300387

农业农村农民问题是关系国计民生的根本性问题,“三农”问题的核心是农民问题。党的十八大以来,广大农民的获得感得到了大幅提升,但还不平衡不持续。最主要原因是乡村制度体系供给不充分与运转不顺畅,新时代农民需求与制度供给之间存在... 详细信息

农业农村农民问题是关系国计民生的根本性问题,“三农”问题的核心是农民问题。党的十八大以来,广大农民的获得感得到了大幅提升,但还不平衡不持续。最主要原因是乡村制度体系供给不充分与运转不顺畅,新时代农民需求与制度供给之间存在一些错位。提升新时代农民获得感需要充分发挥乡村制度体系供给的系统集成作用,从保障农民经济利益和政治权利的制度设计理念出发,坚持党领导农村工作的根本制度,不断优化农村基本经营制度、农村治理制度与城乡融合制度等基本制度体系,进一步完善农村合作医疗制度与农村养老制度等重要制度体系。

关键词：新时代农民获得感乡村制度体系供给精准对接

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社会主义制度认同的历史经验

河南社会科学 2019年第3期27卷 17-23页

作者：孔德永天津师范大学马克思主义学院天津300387

社会主义制度确立以来,走过了一段艰辛的历程,社会主义运动与实践给我们留下了宝贵的历史经验。要赢得人民群众对社会主义制度的认同,需要提高社会主义制度的认知水平;要认真开展对社会主义污名化现象的斗争,增强社会主义意识形态的价... 详细信息

社会主义制度确立以来,走过了一段艰辛的历程,社会主义运动与实践给我们留下了宝贵的历史经验。要赢得人民群众对社会主义制度的认同,需要提高社会主义制度的认知水平;要认真开展对社会主义污名化现象的斗争,增强社会主义意识形态的价值认同;全面从严治党,提升社会主义制度的形象认同;要让人民群众享有实实在在的获得感,培育社会主义制度的情感认同。人民群众对社会主义制度的认知、认同是一个动态的历史过程,社会主义制度的确立、成熟到定型不是一蹴而就的,只有始终坚持人民的主体地位,改革与完善社会主义体制与机制,不断创新,才能提升人民群众对社会主义制度的认同度,才能坚定人民群众走社会主义道路的道路自信。

关键词：社会主义制度认同历史经验

制度-效能:基层党建引领社区治理的创新实践——以天津市“战区制、主官上、权下放”模式为例

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中共天津市委党校学报 2020年第1期22卷 16-24页

作者：师林孔德永天津师范大学马克思主义学院天津300387 天津美术学院思政课部

基层党建引领社区治理是实现制度优势向治理效能转化的重要路径。部分基层党组织缺乏组织力、领导力,街道与社区等社区治理主体职责界定不明晰、治理载体单一,导致以党建推动社区治理制度向效能转化存在困境。天津市“战区制、主官上、... 详细信息

基层党建引领社区治理是实现制度优势向治理效能转化的重要路径。部分基层党组织缺乏组织力、领导力,街道与社区等社区治理主体职责界定不明晰、治理载体单一,导致以党建推动社区治理制度向效能转化存在困境。天津市“战区制、主官上、权下放”模式着力强化基层党组织建设、明确街道与社区作为社区治理“主战区”、强调领导干部这个“关键少数”的主体责任、坚持治理重心下沉,有效推动了党建引领基层治理的体制机制创新。新时代提高社区治理效能必须坚持以党建为引领、以基层为主体、以人民为中心、以问题为导向、以创新为手段、以制度为保障,构建基层社会治理新格局。

关键词：基层党建社区治理基层治理“主战区” 领导责任制治理重心下沉

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我国城市治理改革趋向

开放导报 2015年第3期 7-12页

作者：陈文孔德勇深圳大学广东深圳518060

我国城市治理面临着治理理念滞后、治理体制局限、依法治理能力不足、市民参与欠缺、治理方式粗陋、大都市协同治理机制缺失等困境,亟需完善城市治理立法体系,健全城市管理执法体制,压缩城市管理层级,建立健全部门协调联动机制,促进居... 详细信息

我国城市治理面临着治理理念滞后、治理体制局限、依法治理能力不足、市民参与欠缺、治理方式粗陋、大都市协同治理机制缺失等困境,亟需完善城市治理立法体系,健全城市管理执法体制,压缩城市管理层级,建立健全部门协调联动机制,促进居民有序参与,提高城市治理的精细化和信息化水平,完善城市群协同治理机制。

关键词：城市治理现实困境改革趋向