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Congenital Cervical Teratoma

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Surgical Science 2019年第1期10卷 44-48页

作者： Fatogoma Issa koné Amal Hajjij Naouma Cissé Siaka Soumaoro Abdoul Wahabhaidara Samba Karim Timbo Mohamed amadou Keita Department of Head and Neck Surgery Gabriel Touré University Hospital Bamako Mali Department of Head and Neck Surgery University of Health Sciences (UM6SS) International University Hospital Mohamed VI Casablanca Morocco

Introduction: The word “Teratoma” derives from the Greek word “teratos” including the meaning show. Teratoid tumors derived from the transformation of multipotent germ cells. They are composed of ectodermal, endodermic and mesodermal tissues in variable proportions;hence the term “embryonic tumor”. Objectives: We are reporting the case of a mature teratoma discovered in a young child whose delivery was vaginally performed. Through this case we put in diagnostic and therapeutic highlight and we made a literature review. Case report: Patient 17 months admitted for the anterior compartment mass associated with inspiratory dyspnea. No anomaly/abnormality was detected during the follow-up of the pregnancy. The Patient with dyspnea grade 2 was admitted according to Chevaleir-Jackson classification. No abnormalities of stature ponderal developments were noted. Surgery of excision was our therapeutic alternative. Through the pathological examination a mature teratoma was found. Conclusion: Teratoma is a rare condition. Proper management of mature teratoma helps to prevent recurrence.

关键词： Mature Teratoma Congenital Neck Surgery

Synchronous Volvulus of the Sigmoid Colon and the Transverse Colon: A Case Report at Gabriel Toure University Hospital in Mali

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Surgical Science 2021年第9期12卷 313-318页

作者： Traoré amadou konaté Madiassa Diarra Abdoulaye Tounkara Idrissa Saye Zakari Doumbia Arouna Bah amadou Sidibé Boubacar Yoro Maïga amadou koné Tani Thiam Souleymane Karembé Boubacar Kelly Bouréima Traoré Kadia Kéita koniba Bouaré Yacouba koné Assitan Diakité Ibrahim Diakité Ibrahim Dembélé Bakary Tientigui Traoré Alhassane Togo Adégné General Surgery Department Gabriel Touré University Hospital Bamako Mali Surgery Department Kati University Hospital Kati Mali Reference Health Center of Commune III Bamako Mali

Synchronous transverse and sigmoid colon volvulus are very rare. We report the case of a 23-year-old man who underwent emergency surgery for sigmoid colon volvulus. An intraoperative finding of transverse colon volvulus associated with sigmoid colon volvulus was made. Left and transverse colectomy was performed followed by colorectal anastomosis. The postoperative period was uneventful. Synchronous volvulus of the transverse and sigmoid colon is a surgical emergency. The clinical signs are not specific and the discovery is often intraoperative. It is necessary to know how to evoke the diagnosis in a case of sigmoid colon volvulus, to avoid inadequate management with dramatic consequences.

关键词： Volvulus Synchronous Colon Sigmoid Transverse Surgery Mali

Antioxidant Activity and Phenolic Compounds Content of Extracts from Ceratotheca sesamoides Endl and Striga hermonthica (Delille) Benth Used as Antheminthic in Burkina Faso

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Journal of Biosciences and Medicines 2022年第11期10卷 203-213页

作者： Dicko amadou Kam Eric Sami Hadidjatou Belem konaté Almamy Tindano Basile Meda Roland Nâg-Tiéro Ahoua Angora Rémi Constant koné Mamidou Witabouna Kaboré Adama Traoré amadou Bayala Balé Tamboura Hamidou Hamadou Laboratoire de Biologie et Santé Animale (LaBioSA) Centre National de recherche Scientifique et Technologique (CNRST)/Institut de l’Environnement et de Recherches Agricoles (INERA) Ouagadougou Burkina Faso Laboratoire de Recherche et d’Enseignement en Santé et Biotechnologies Animales Unité de Formation et de Recherches en Sciences et Technique Université Nazi BONI Bobo Dioulasso Burkina Faso Laboratoire de Physiologie Animale (LaPA) Unité de Formation et de Recherches en Sciences de la vie et de la Terre Université Joseph KI-ZERBO Ouagadougou Burkina Faso Laboratoire de Botanique et Valorisation de la Diversité Végétale (LaBVDIV) Université Nangui Abrogoua Abidjan C&ocirc te d’Ivoire Centre Suisse de Recherche en Cô te d’Ivoire Abidjan C&ocirc te d’Ivoire

The revaluation of medicinal plants in the veterinary pharmacopoeia is essential for the development of livestock in Burkina Faso. In order to justify the use of C. sesamoides and S. hermonthica in the treatment of gastrointestinal parasitosis of small ruminants, a quantification of phenolic compounds as well as antioxidant activity and acute toxicité evaluation of both plants were performed. Acute toxicity was evaluated by administering a single dose of 2000 mg/kg body weight of aqueous extract of both plants to mice. The highest total polyphenol content for C. sesamo?des was obtained in the ethyl acetate fraction with 47.236 ± 2.57 mgEAG/100mg while that of S. hermonthica was 74.871 ± 2.57 mgEAG/100mg obtained with the n-butanol Fraction. The dichloromethane extract of S. hermonthica obtained the highest total flavonoid content with 7.31 ± 0.48 mgEQ/100 while the highest total flavonoid content of C. sesamo?des was obtained with ethyl acetate fraction with 5.4273 ± 0.35 mgEQ/100mg. The aqueous extract of C. sesamo?des obtained the highest content of condensed tannins with 3.028 ± 0.13 mgEAT/100mg. Both plant’s extracts did not show any signs of toxicity in NMRI mice after administration of the dose of 2000 mg/kg. The antioxidant activity by DPPH, FRAP and ABTS methods was good compared to those of Quercetin and Trolox taken as standard.

关键词： C. sesamoides S. hermonthica Polyphénols Content Flavonoids Content Condensed Tannins Antioxidant Activity

Bladder Cancer: Epidemiological, Clinical and Histopathological Aspects at the University Hospital Point G, Mali

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Open Journal of Urology 2021年第10期11卷 343-350页

作者： Honoré Jean Gabriel Berthé Dramane Cissé Moussa Salifou Diallo amadou Kassogué Alkadri Diarra Mamadou Tidiani Coulibaly Mamadou Lamine Diakité Modibo Coulibaly Mory koné Université des Sciences des Techniques et des Technologies de Bamako Bamako Mali CHU du Point G Bamako Bamako Mali Hô pital Sominé DOLO de Mopti Mopti Mali CHU Kati Kati Mali CHU Luxembourg Bamako Mali CHU Gabriel TOURE Bamako Bamako Mali

Introduction: Bladder cancer is a new tissue formation most often of urothelial origin with potential for local, locoregional and distant invasion. Among its risk factors, urinary bilharzia is endemic in our study area. The aim of our study was to present the epidemiological, clinical and histopathological aspects of bladder cancer in our department. Patients and method: This was a descriptive cross-sectional study over a 12-month period from January 1 to December 31, 2019. The study took place in the urology department of the university hospital Point “G”. It included all patients hospitalized for bladder cancer. The epidemiological, clinical and histopathological characteristics have been sought and described. Results: A total of 74 patients were included in the study. Bladder cancer was the leading cause of cancer, accounting for 57.9% of all urological cancers. The mean age of the patients was 52.8 ± 16.25 years. A slight male predominance was observed with a sex-ratio of 1.2. Housewives were the most represented with 43.2% followed by farmers with 24.3%. Hematuria was the reason for consultation in 87.8% cases. The main risk factors found were urinary schistosomiasis (48.6%) and smoking (31.1%). These two factors were associated in 23.0% of cases. At diagnosis, 85.7% of patients were classified as T3 or T4 stage. Squamous cell carcinoma with 58.2% was the most common histological type followed by urothelial carcinoma in 26.0% of cases. Conclusion: Bladder cancer is very common of cancer in hospitalized patients in our department. Diagnosis is more often made at an advanced stage. The most common histological type is squamous cell carcinoma.

关键词： Bladder Cancer Epidemiology Clinic Histopathology

Routine Screening for Cervical Cancer

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Open Journal of Obstetrics and Gynecology 2021年第7期11卷 922-928页

作者： Alassane Traoré Aphou Sallé koné Sima Mamadou amadou Bocoum Mamadou Bakary Coulibaly koninba Diabaté Adama Diakité Kanté Ibrahim Seydou Mariko Idrissa Mama Diarra Service de gynécologie H&ocirc pital du Mali Bamako Mali Service de radiothérapie H&ocirc pital du Mali Bamako Mali Service de gynécologie-obstétrique Centre hospitalier et universitaire du Point G Bamako Mali Service de gynécologie-obstétrique Centre hospitalier et universitaire Gabriel Touré Bamako Mali

Objective: To describe the screening for uterine cancer by visual methods. Method: We conducted a prospective and descriptive study over a period of 12 months from January to December 2020. Direct observation of providers and interview of patients were performed for data collection. Results: Out of 3400 patients, 1024 were enrolled for the study, or 30.11%. The average age of the patients was 41 years with the extremes of 17 to 87 years. Women aged 40 to 45 were the most represented with 58.78%, (n = 602). Housewives 85.83% (n = 879), they had a primary education level in 71.09% of cases (n = 728), the vast majority were married 92.28% (n = 945). Multiparous represented 58.78% (n = 602) of the sample, nulliparous 18.26% (n = 187), women living in rural areas 30.17% (n = 309), in urban areas 69.82% (n = 715). The test was positive in 43 patients (4.19%) but squamocylindrical junction was not visible in 17% of cases. The preparation of acetic acid and lugol: good preparation in 100% of cases;

Treatment of Operative Pain in Visceral Cancer Surgery at CHU Gabriel Toure

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Surgical Science 2017年第1期8卷 47-51页

作者： Dembélé Bakary Tientigui Traoré Alhassane Togo Adégné Kante Lassana Diakité Ibrahim konate Madiassa Traore amadou Diakité Boubacar Bah amadou Sidibé Yoro koné Tany Diop Thiorno Madani Django Djibo Diallo Gangaly Department of General Surgery CHU Gabriel-Touré Bamako Mali

The objectives were to determine the frequency of pain in cancer patients and its intensity in cancer pathologies and to evaluate the evolution of pain intensity after analgesic treatment;the effectiveness of its management study involved 121 cases of operated gastrointestinal cancers, which accounted for 85.82% (141) of operated cancers and 16.78% (721) of all operated patients;the average age of our patients was 49.93 years with extremes 17 and 78 years. Standard deviation: 15.75;with a sex ratio of 1.46. The majority of our patients had WHO III (54/121) or 44.6%;46.3% (56/121) of patients were in stage IV of the TNM classification. The main digestive cancers were cancer of the esophagus 4 cases (3.3%);of the stomach 61 cases (50.4%);of the pancreas 7 cases (5.8%);of the liver 4 cases (3.3%);gall bladder 2 cases (1.6%);colon 33 cases (27.3%);rectum 6 cases (4.9%) and hail 4 cases (3.3%). The average pain intensities were 3 to 6 hour;2 to 24 hour;1.6 to 48 hour;and 1.2 to 72 hour. The majority of our patients had a treatment protocol involving nefopam, and paracetamol was 58%. The pain was exacerbated especially during exercise. Vomiting and vein burning were the main side effects encountered.

关键词： Pain Cancer Bamako Surgery Mali

Takayasu Disease Revealed by Arterial Hypertension in a 47-Year-Old Man

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World Journal of Cardiovascular Diseases 2023年第7期13卷 341-348页

作者： Bah Mamadou Bassirou Baldé Thierno Hamidou Wann Thierno amadou Baldé Elhadj Yaya Baldé Aissatou Tiguidanké koné Alpha Doumbouya amadou Diouldé Diallo Hafsatou Barry Ibrahima Sory Samoura Sana Diakité Souleymane Béavogui Mariam Baldé Mamadou Dadhi Cardiology Department Ignace Deen Hospital Conakry Guinea Department of Imaging Ignace Deen Hospital Conakry Guinea Department of Internal Medicine Donka Hospital Conakry Guinea Cardiology Department Donka Hospital Conakry Guinea

Takayasu disease is a chronic vasculitis of the large vessels. It is rare in sub- Saharan Africa and probably under-diagnosed. Arterial hypertension (AH) is a frequent finding. We report the case of a 46-year-old man with Takayasu disease revealed by hypertension. The American College of Rheumatology (ACR) criteria were used for diagnosis, with 4 out of 6 criteria. Echodoppler and angioscanner showed signs of left subclavian stenosis and circumferential, regular arterial thickening. He had a biological inflammatory syndrome. He was treated with prednisone and amlodipine. After 6 months of follow-up, he was diagnosed with tuberculosis and put on anti-tuberculosis treatment.

关键词： Takayasu Disease Hypertension Man

Deafness: Epidemiological, Clinical and Therapeutic Aspects in 15 Year Olds and over at the University Hospital Center Gabriel Toure of Bamako

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第4期11卷 202-210页

作者： Kassim Diarra N’faly konaté Yaya Dembele Ismael Berthé Drissa Kaloga Bagayoko Boubacary Guindo Fatogoma Issa koné Siaka Soumaoro Doumbia Kadidiatou Singare Mohamed amadou Keita ENT and Head and Neck Surgery Department university hospital Gabriel Toure Bamako Mali Armies Polyclinic of the Kati Bamako Mali Department of Anesthesia Resuscitation CHU Mother-Child “Luxembourg” Bamako Mali

Objective: To study the epidemiological, clinical and therapeutic aspects of hearing loss in 15-year-olds and over at the CHU GT of Bamako. Materials and Method: This is a longitudinal prospective study carried out in the ENT department of the University hospital Gabriel Toure in Bamako over 13 months (from September 2018 to September 2019). We carried out an exhaustive sampling of all the patients who consulted in the department for hearing loss and whose deafness was confirmed at pure tone audiometry with age greater than or equal to 15 years. The exclusion criteria were all patients under the age of 15 as well as a hearing loss related to earwax or foreign bodies and refusals to participate in the study. Results: Two hundred and thirty (230) patients were collected during the study. Dominated by the male sex with a sex ratio of 1.5 or 3 men for 2 women, with an average age of 38.16 ± 19 years with extremes ranging from 15 to 86 years. Among our patients, 37.40% had unilateral deafness, progressive installation evolving more than 12 weeks with a rate of cases had headaches 41% and had a history of chronic otitis media (CMO) 27%. There were a few cases of mixed type deafness, 30% had mild deafness, 22% moderate deafness and 40% severe deafness, according to the BIAP classification. Among our patients, 22.16% had conductive hearing loss, and those with sensorineural hearing loss accounted for 15.24%. Conclusion: Pure tone audiometry remains essential in the diagnosis of deafness. It not only makes it possible to confirm or invalidate the deafness, but also to define the type of deafness and especially to classify the deafness according to the degree of the average hearing loss established by the BIAP.

关键词： Pure Tone Audiometry Deafness BIAP

Postoperative Occlusion of the Small Bowel with Flanges and/or Adhesions in General Surgery of Kati BSS CHU

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Surgical Science 2018年第9期9卷 293-299页

作者： Abdoulaye Diarra koniba Keita amadou Traore Assitan koné Issa Traore Idrissa Tounkara Abdoulaye Kante Fadima K.Tall Daouda Diallo Moustaph Issa Magané Madiassa konate Aboubacar koné Deborah Sanra Sanogo Ismael konare Alhassane Traoré General Surgery Department KatiMali Anesthesia Service and Resuscitation Department KatiMali Gastroenterology Department KatiMali

Objectives were to determine the frequency, describe the epidemiological and clinical aspects, therapeutic and analyze the postoperative course. Methodology: This was a retrospective study that covered 08 years (January 2009-December 2017). Inclusion criteria: all patients operated for obstruction of the small bowel by hail and/or flanging. Exclusion criteria: other types of occlusion and non-operated patients. Result: We recorded a total of 162 cases of hail obstruction by adhesions and/or flanges at 2.87%. The average age was 32.04, the sex ratio was 1.2. The average consultation time was 4 days. Abdominal pain associated with stopping of material and gas was present in all our patients. X-ray of the abdomen without preparation carried out in all the patients made it possible to objectify in 150 patients (92.6%) of the hydro-hail levels. Inoperative occlusion of hail on flange was present in 80 patients (49.4%). Occlusion of the small bowel on flange and adhesion was present in 69 patients. Adhesion obstruction of hail accounted for 6.8% (11 cases). The most commonly used surgical technique was flange resection in 91 patients (56.2%). The follow-up was simple in 151 patients (93.2%). Mortality was 1.2% of cases, i.e. 2 deaths. The average duration of hospitalization was 6 days. Conclusion: Occlusion of the small bowel by flanging and/or adherence is a surgical emergency whose prognosis depends on early management.

关键词： Postoperative Occlusion Hail Bridle/Adherence Mali