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Dipeptidyl peptidase-4 inhibitor for steroid-induced diabetes

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World Journal of Diabetes 2010年第3期1卷 99-100页

作者： Hidekatsu Yanai Yoshinori masui Reo Yoshikawa Junwa Kunimatsu Hiroshi Kaneko Department of Internal Medicine Kohnodai Hospital National Center for Global Health and Medicine Department of Rheumatology Kohnodai Hospital National Center for Global Health and Medicine

The addition of the dipeptidyl peptidase-4 (DDP-4) inhibitor has been reported to achieve greater improvements in glucose metabolism with fewer adverse events compared to increasing the metformin dose in type 2 diabetic patients. We present a patient with steroid-induced diabetes whose blood glucose levels were ameliorated by the use of the DPP-4 inhibitor, showing that the DPP-4 inhibitors may be an effective and safe oral anti-diabetic drug for steroid-induced diabetes.

关键词： Dipeptidyl peptidase-4 Nateglinide Sitagliptin Steroid-induced diabetes

Mutual Experiences of Japanese Parents and Their Children When Late School-Age Children Engage in Meal-Related Family Routines: A Qualitative Analysis of Parent and Child Dyads

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Open Journal of Nursing 2022年第6期12卷 444-458页

作者： Saeko Ando Tae Kawahara Nagisa Yasui Maiko Yasuzato Marie Tabayashi Yui masui Akemi Yamazaki Department of Nursing Faculty of Nursing and Rehabilitation Konan Women’s University Kobe Japan Division of Health Sciences Graduate School of Medicine at Osaka University Osaka Japan

Purpose: The objective of the present study was to identify the type of experiences that parents and their children have with each other when late-school age children take on roles in family routines related to daily meals. Methods: A grounded theory approach was used. The participants were children in the 4th, 5th, and 6th grades of elementary school and their main caregivers. First, 10 parent and child dyads were interviewed using a semi-structured schedule. Next, online group interviews were conducted for 17 parent and child dyads to deductively confirm the categories. Results: The average age of the subjects was 41.9 years for parents and 10.4 years for children in parent-child interviews, and 41.1 years for parents and 9.6 years for children in group interviews. Six categories emerged with nineteen subcategories. Conclusions: Experiences mutually nurtured by parents and their children included experiences in which children used negotiation and conversation skills to consensually engage in family routines related to meals. It also included experiences that socialized the children in family life and fostered good communication. The six categories will be useful for healthcare professionals and school authorities in providing health guidance that addresses health functions of late school-age children and their families.

关键词： Family Meals Late School Age Children Family Role Family Communication

Selective Monoprotection of Symmetrical Diols in a Flow Reactor

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International Journal of Organic Chemistry 2018年第2期8卷 264-271页

作者： Hisashi masui Masaru Takizawa Yuki Sakai Yasuhiro Kajiwara Kiyofumi Wanibuchi Mitsuru Shoji Takashi Takahashi Department of Pharmaceutical Sciences Yokohama University of Pharmacy Yokohama Japan

Desymmetrization reactions provide a powerful approach for the construction of complex molecules. Various methods have been developed for the selective monoprotection of symmetrical diols;however, their application to large-scale operations is limited. In this study, the monotetrahydropyranylation of symmetrical diols in a flow reactor has been developed, whereby the length of the flow reactor tube and the amount of acid were optimized. A higher selectivity for the monoprotected derivative was observed when the reaction was performed in a flow reactor compared with that observed in a conventional batch experiment. The efficient flow method developed herein can be applied to large-scale synthesis by numbering up the flow reactor without affecting the selectivity and yield. Since monoprotection can be achieved without using a large excess of diol, our developed flow method is effective when expensive diol must be used.

关键词： Desymmetrization Selective Monoprotection Flow Synthesis Diols Tetrahydropyranylation

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熔化石英球体体积的确定

宇航计测技术 1991年第6期10卷 23-27页

作者： K.Fujii R.masui S.Seino 冷德梅

描述了对水的密度进行绝对测量的熔化石英球体体积的确定。此球体的直径用光学干涉仪测量,即将此球体放置在两个平行标准板之间,而其间距的精确值已知。通过测量每块标准板表面到球体之间的间隙而测得其直径。为了使用精确的分数法,采... 详细信息

描述了对水的密度进行绝对测量的熔化石英球体体积的确定。此球体的直径用光学干涉仪测量,即将此球体放置在两个平行标准板之间,而其间距的精确值已知。通过测量每块标准板表面到球体之间的间隙而测得其直径。为了使用精确的分数法,采用了两种波长:频率稳定的 He-Ne 激光器为633nm 及 He-Cd 激光器为441nm。详细阐述了为干涉仪克服熔化石英表面的低反射性而采取的特殊安排。同时,也介绍了一种消除由于石英球体的透明性而引起的伪效应的方法。此直径(大约85mm)测得值的标准偏差为5～12nm,体积上就相当于0.16～0.43ppm(1ppm=1×10^(-6)),此体积的总不确定度估计为0.26～0.48ppm。

关键词：熔化石英球体体积干涉仪

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住友可变凸度轧辊系统的发展

常冶科技通讯 1989年第1期 31-40页

作者： masui.,T 顾俭

新杀菌剂Befran(iminoctadine)

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世界农药 1987年第3期 59-61页

作者： Masaaki masui 茹仲贤大日本油墨化学公司

Befran是大日本油墨化学公司开发的一种新型的广谱杀菌剂。在日本,该药剂不仅作为果树休眠期喷洒药剂,而且作为谷类作物的叶面喷洒剂,进行了广泛的试验。Befran的有效成份是一种醋酸双胍盐。双胍盐是大约在1968年开发的杀菌剂,目前主要... 详细信息

Befran是大日本油墨化学公司开发的一种新型的广谱杀菌剂。在日本,该药剂不仅作为果树休眠期喷洒药剂,而且作为谷类作物的叶面喷洒剂,进行了广泛的试验。Befran的有效成份是一种醋酸双胍盐。双胍盐是大约在1968年开发的杀菌剂,目前主要在欧洲用于防治谷类种子病害和收获后柑橘贮藏期病害。这类双胍盐含有不规则的1,8-二氨基辛烷及更高级的齐聚物,例如:二辛基甲撑三胺、三辛基甲撑四胺等胍盐。

关键词：有效成份液剂 iminoctadine Befran 柑橘绿霉病柑橘青霉病苹果腐烂病可湿性粉剂农药剂型农业实验站双肌离体试验油墨糊剂苹果花腐病

南海海槽东部首个天然气生产试验站位含水合物浊积岩储层的力学性质

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海洋地质 2016年第2期32卷 1-18页

作者： Jun Yoneda Akira masui Yoshihiro Konno 杨振不详广州海洋地质调查局

研究海底沉积物力学性质对于地质灾害（如：海底滑坡、海底沉降）发生的预测和海洋工业海底施工的设计都具有重要的意义。本次研究，对含天然气水合物的砂质和泥质一粉砂质沉积物进行了三轴应力测试。在南海海槽东部，通过保压取心获得... 详细信息

研究海底沉积物力学性质对于地质灾害（如：海底滑坡、海底沉降）发生的预测和海洋工业海底施工的设计都具有重要的意义。本次研究，对含天然气水合物的砂质和泥质一粉砂质沉积物进行了三轴应力测试。在南海海槽东部，通过保压取心获得了这些沉积物，同时该区域也是日本第一个海洋水合物生产试验区。对沉积物进行了各种属性测试，其中孔隙度约为40％-50％，并随着距海底深度的增加而逐渐减小。泥质．粉砂质沉积物的粒度小于10μm，而砂质沉积物的粒度约100μm。渗透率的估算是利用三轴应力试验的固结过程和X射线衍射分析等技术手段，取决于云母、高岭石和蒙脱石等细粒沉积物的含量。对于泥质-粉砂质沉积物进行含水压力测试的结果显示，其远大于各种条件下所测试的孔隙压力值。这一力学行为表明所取得的岩心样品为正常固结沉积物。脱水压力测试的结果表明，砂质沉积物的强度和刚度随水合物饱和度的增加而增加。此外，水合物储层的体积应变从压缩变为膨胀。结果显示水合物饱和度值超过70％。南海海槽东部水合物浊积岩储集层的剪切强度为围压的函数。

关键词：含水合物砂层三轴应力试验保压取心力学性质水合物饱和度

Laparoscopic Gastrectomy with Preservation of the Vagus Nerve Accompanied by Lymph Node Dissection for Early Gastric Carcinoma

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Laparoscopic Gastrectomy with Preservation of the Vagus Nerv...

Irsogladine maleate and rabeprazole in non-erosive reflux disease: A double-blind, placebo-controlled study

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作者： Ichiro Uyama Yoichi Sakurai Yoshiyuki Komori Yasuko Nakamura Mitsutaka Syoji Syuhei Tonomura Ikuo Yoshida Toshihiko masui Masahiro Ochiai Department of Surgery Fujita Health UniversitySchool of MedicineDengakugakuboKutsukake-choToyoakeAichiJapan MD Department of Surgery Fujita Health UniversitySchool of MedicineDengakugakuboKutsukake-choToyoakeAichiJapan MD FACS

Various types of function-preserving gastrectomy and limited gastrectomy have been performed in attempts to improve postoperative quality of life for early gastric *** with preservation of the vagus nerve, which is one of the noteworthy procedures, is performed in Japan to reduce occurrence of cholelithiasis and minimize loss of digestive and absorptive function. Because it is less invasive, the laparoscopic approach is used to treat early gastric *** are few reports in the English literature of laparoscopic

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World Journal of Gastroenterology 2015年第16期21卷 5023-5031页

作者： Takayoshi Suzuki Masashi Matsushima Aya masui Shingo Tsuda Jin Imai Jun Nakamura Yoko Tsukune Tetsufumi Uchida Hiroki Yuhara Muneki Igarashi Jun Koike Tetsuya Mine Division of Gastroenterology and Hepatology Department of Internal MedicineTokai University School of Medicine

AIM:To evaluate the efficacy of adding irsogladine maleate(IM) to proton-pump inhibitor(PPI) therapy in non-erosive reflux disease(NERD) ***:One hundred patients with NERD were recruited and randomized to receive rabeprazole plus IM(group I) or rabeprazole plus placebo(group P).The efficacy of the treatment was assessed using the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease(FSSG) and the short form(SF)-36 quality of life questionnaires after four weeks of *** also assessed whether patients with NERD with minimal changes(grade M) had different responses to the therapies compared with patients who did not have minimal changes(grade N).RESULTS:Group I and group P showed significant improvements in their FSSG scores after the treatment(from 17.9 ± 7.9 to 9.0 ± 7.6, and from 17.7 ± 7.3 to 11.2 ± 7.9, respectively, P = 0.0001), but there was no statistically significant difference between the FSSG scores in group I and those in group *** analysis showed that significant improvements in the FSSG scores occurred in the patients in group I who had NERD grade N(modified Los Angeles classification)(7.8 ± 7.4 vs 12.5 ± 9.8, P = 0.041).The SF-36 scores for patients with NERD grade N who had received IM and rabeprazole were significantly improved in relation to their vitality and mental health ***:The addition of IM to rabeprazole significantly improves gastroesophageal reflux diseasesymptoms and the quality of the lives of patients with NERD grade N.

关键词： Irsogladine maleate Rabeprazole Nonerosivereflux disease Randomized controlled trial Frequency scale for the symptoms of gastroesophagealreflux disease Quality of life