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Unilateral branch retinal artery occlusion in association with COVID-19:a case report

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 777-782页

作者： Kunihiko Hirosawa Takenori Inomata Jaemyoung Sung Yuki Morooka Tianxiang Huang Yasutsugu Akasaki Yuichi okumura Ken Nagino Kaho Omori Shintaro Nakao Department of Ophthalmology Juntendo University Graduate School of Medicine2-1-1 HongoBunkyo-kuTokyo 113-0033Japan Department of Digital Medicine Juntendo University Graduate School of Medicine2-1-1 HongoBunkyo-kuTokyo 113-0033Japan Department of Telemedicine and Mobile Health Juntendo University Graduate School of Medicine2-1-1 HongoBunkyo-kuTokyo 113-0033Japan Department of Hospital Administration Juntendo University Graduate School of Medicine2-1-1 HongoBunkyo-kuTokyo 113-0033Japan AI Incubation Farm Juntendo University Graduate School of Medicine2-1-1 HongoBunkyo-kuTokyo 113-0033Japan Department of Ophthalmology Tulane University School of MedicineNew OrleansLA 70112USA

Dear Editor,I am Kunihiko Hirosawa of the Department of Ophthalmology at Juntendo University Hospital.I am writing to present a case of concomitant Coronavirus Disease 2019(COVID-19)with branch retinal artery occlusion(BRAO).BRAO presents as a sudden,painless loss of vision on the afflicted side and is most often focal in nature[1].

关键词： branch COV occlusion

Re:Association between intestinal neoplasms and celiac disease-beyond celiac disease and more

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World Journal of Gastrointestinal Oncology 2022年第3期14卷 746-747页

作者： Kenji okumura Department of Surgery Westchester Medical Center/New York Medical CollegeValhallaNY 10595United States

The association between celiac disease and enteropathy-associated T cell lymphoma has been *** pathogenesis of the development of malignant neoplasms remains *** addition to celiac disease,we believe that other underl... 详细信息

关键词： Celiac disease Entropathy-associated T cell lymphoma c-MYC JAK-STAT

Analysis for Effects of Temperature Rise of PV Modules upon Driving Distance of Vehicle Integrated Photovoltaic Electric Vehicles

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Energy and Power Engineering 2024年第4期16卷 131-150页

作者： Masafumi Yamaguchi Yasuyuki Ota Taizo Masuda Christian Thiel Anastasios Tsakalidis Arnulf Jaeger-Waldau Kenji Araki Kensuke Nishioka Tatsuya Takamoto Takashi Nakado Kazumi Yamada Tsutomu Tanimoto Yosuke Tomita Yusuke Zushi Kenichi okumura Takashi Mabuchi Akinori Satou Kyotaro Nakamura Ryo Ozaki Nobuaki Kojima Yoshio Ohshita Toyota Technological Institute Nagoya Japan Faculty of Engineering Miyazaki University Miyazaki Japan Toyota Motor Corporation Susono Japan European Commission— Joint Research Centre Ispra Italy Sharp Corporation Nara Japan Toyota Motor Corporation Toyota Japan Nissan Motor Corporation Yokosuka Japan

The development of vehicle integrated photovoltaics-powered electric vehicles (VIPV-EV) significantly reduces CO2 emissions from the transport sector to realize a decarbonized society. Although long-distance driving of VIPV-EV without electricity charging is expected in sunny regions, driving distance of VIPV-EV is affected by climate conditions such as solar irradiation and temperature rise of PV modules. In this paper, detailed analytical results for effects of climate conditions such as solar irradiation and temperature rise of PV modules upon driving distance of the VIPV-EV were presented by using test data for Toyota Prius and Nissan Van demonstration cars installed with high-efficiency InGaP/GaAs/InGaAs 3-junction solar cell modules with a module efficiency of more than 30%. The temperature rise of some PV modules studied in this study was shown to be expressed by some coefficients related to solar irradiation, wind speed and radiative cooling. The potential of VIPV-EV to be deployed in 10 major cities was also analyzed. Although sunshine cities such as Phoenix show the high reduction ratio of driving range with 17% due to temperature rise of VIPV modules, populous cities such as Tokyo show low reduction ratio of 9%. It was also shown in this paper that the difference between the driving distance of VIPV-EV driving in the morning and the afternoon is due to PV modules’ radiative cooling. In addition, the importance of heat dissipation of PV modules and the development of high-efficiency PV modules with better temperature coefficients was suggested in order to expand driving range of VIPV-EV. The effects of air-conditioner usage and partial shading in addition to the effects of temperature rise of VIPV modules were suggested as the other power losses of VIPV-EV.

关键词： Vehicle Integrated Photovoltaics (VIPV) VIPV-Powered Electric Vehicles Driving Distance PV Modules Solar Irradiation Temperature Rise Radiative Cooling

聚合物稳定的金纳米簇催化:理论计算与实验的相互影响（英文）

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Chinese Journal of Catalysis 2016年第10期37卷 1588-1593页

作者： Hiroaki Koga Yoshinori Ato Akihide Hayashi kohei Tada Mitsutaka okumura 京都大学催化剂与电池元素战略研究基地大阪大学科学研究院化学系

平均粒径为2–10 nm的聚合物稳定的Au纳米簇(NCs)表现出独特的催化性能.多个研究表明,影响聚合物稳定的AuNCs催化活性的主要因素为:AuNC尺寸的控制、聚合物的选择以及反应条件的优化.这是由于聚合物稳定的AuNCs在多个催化反应中表现出... 详细信息

平均粒径为2–10 nm的聚合物稳定的Au纳米簇(NCs)表现出独特的催化性能.多个研究表明,影响聚合物稳定的AuNCs催化活性的主要因素为:AuNC尺寸的控制、聚合物的选择以及反应条件的优化.这是由于聚合物稳定的AuNCs在多个催化反应中表现出明显的尺寸效应,其催化活性也因所采用的聚合物和反应条件的不同而不同.为了阐明影响聚合物稳定的AuNCs催化活性的内在原因,众多研究者关注于聚合物稳定的AuNCs催化中的理论计算与实验的相互影响.本文主要总结了聚合物稳定的AuNCs中这种相互影响的研究进展.

关键词：聚合物稳定的金纳米簇醇的有氧氧化理论计算和实验的相互影响金纳米簇的尺寸效应聚合物的作用

Acute kidney injury and the compensation of kidney function after nephrectomy in living donation

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World Journal of Transplantation 2022年第8期12卷 223-230页

作者： Kenji okumura Holly Grace Hiroshi Sogawa Shigeyoshi Yamanaga Department of Surgery Westchester Medical Center/New York Medical CollegeValhallaNY 10595United States Department of Surgery New York Medical CollegeValhallaNY 10595United States Department of Surgery Japanese Red Cross Kumamoto HospitalKumamoto 861-8520Japan

Acute kidney injury(AKI)incidence is growing rapidly,and AKI is one of the predictors of inpatient *** nephrectomy,all the patients have decreased kidney function with AKI and recover from ***,the characteristic and behavior of AKI is different from usual AKI and compensatory kidney function has been well known in the postoperative setting,especially in living *** this review,we have focused on the compensation of kidney function after nephrectomy in living *** discuss factors that have been identified as being associated with kidney recovery in donors including age,sex,body mass index,remnant kidney volume,estimated glomerular filtration rate,and various comorbidities.

关键词： Acute kidney injury Kidney transplant donor Compensation Kidney function

Mechanism of Tonal Noise Generation from Circular Cylinder with Spiral Fin

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Journal of Thermal Science 2014年第6期23卷 552-557页

作者： Ryo Yamashita Hidechito Hayashi Tetsuya okumura Hiromitsu Hamakawa Department of Mechanical Engineering Nagasaki University1-14 Bunkyo machiNagasaki852-8521Japan Department of Mechanical Engineering Oita University700 Dannoharu Oita870-1192Japan

The pitch of the spiral finned tube influences seriously to the acoustic resonance in the heat *** this research,the flow characteristics in relating to the aeolian tone from the finned cylinder are studied by the numerical *** is observed that the tonal noise generated from the finned tube at two pitch *** ratio of the fin pitch to the cylinder diameter is changed at 0.11 and *** tone level increases and the frequency decreases with the pitch *** separation flow from the cylinder generates the span-wise vortices,Karman vortices,and the separation flow from the fin generates the stream-wise *** the fin pitch ratio is small,the stream-wise vortices line up to span-wise and become weak *** the Karman vortices are remained and integrate in *** the Karman vortex became *** causes the low frequency and the large aeolian tone.

关键词：螺旋翅片管噪声产生音调卡门涡流机制圆柱卡门旋涡热交换器

Function of pioneer neurons specified by the basic helix-loop-helix transcription factor atonal in neural development

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Neural Regeneration Research 2016年第9期11卷 1394-1395页

作者： Misako okumura Takahiro Chihara Department for Evolutionary Biology Max-Planck Institute for Developmental Biology Department of Biological Science Graduate School of ScienceHiroshima University

Basic helix-loop-helix （bHLH） transcription factors regulate the differentiation of various tissues in a vast diversity of species. The bHLH protein Atonal was first identified as a proneural gene involved in the formation of mechanosensory cells and photoreceptor cells in Drosophila （larman et al., 1993, 1994）. Atonal is expressed in sensory organ precursors and is required and sufficient for the development of chordotonal organs （Jar- man et al., 1993）. Moreover, Atonal expression is observed in the developing eye and is essential for the differentiation of R8 photoreceptors, which are the first photoreceptors that appear during development. Atonal is not involved in the formation of other photoreceptors （R1-R7） directly. However, R8 photore- ceptors recruit other photoreceptors from the surrounding cells （Jarman et al., 1994）.

关键词： ORN Function of pioneer neurons specified by the basic helix-loop-helix transcription factor atonal in neural development

The roles of tubulin-folding cofactors in neuronal morphogenesis and disease

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Neural Regeneration Research 2015年第9期10卷 1388-1389页

作者： Misako okumura Masayuki Miura Takahiro Chihara Department of Genetics Graduate School of Pharmaceutical Sciences The University of Tokyo Core Research for Evolutional Science and Technology Japan Science and Technology Agency

Microtubules play important roles in neuronal morphogenesis, including cellular polarization, neurite growth, and branching. A microtubule is a polymer of a- and β-tubulin heterodimers that are formed by a multistep process assisted by at least five tubulin-fold- ing cofactors （TBCA-E）（Lopez-Fanarraga et al., 2001）. Newly syn- thesized α- and β-tubulins associate with the cytosolic chaperonin complex （CCT）, and then the quasi-native tubulins interact with five tubulin-folding cofactors. The α- and β-tubulins first interact with TBCB and TBCA, which are further transferred to TBCE and TBCD, respectively. The α- and β-tubulins, TBCC, TBCD, and TBCE form a supercomplex, and guanosine triphosphate （GTP） hydrolysis occurs within the supercomplex, releasing a tubulin heterodimer. In addition to their functions in tubulin folding and tubulin heterodimer formation, excess amounts of TBCD or TBCE may interact with tubulin heterodimers, leading to their degrada- tion. Thus, tubulin-folding cofactors may play a role in both the synthesis and degradation of tubulin heterodimers.

关键词： The roles of tubulin-folding cofactors in neuronal morphogenesis and disease Figure

Inferior outcomes of liver transplantation for hepatocellular carcinoma during early-COVID-19 pandemic in the United States

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World Journal of Hepatology 2023年第4期15卷 554-563页

作者： Inkyu S Lee Kenji okumura Ryosuke Misawa Hiroshi Sogawa Gregory Veillette Devon John Thomas Diflo Seigo Nishida Abhay Dhand Department of Surgery Westchester Medical CenterValhallaNY 10595United States Department of Medicine Westchester Medical CenterValhallaNY 10595United States

BACKGROUND Early in the coronavirus disease 2019(COVID-19)pandemic,there was a significant impact on routine medical care in the United States,including in fields of transplantation and *** To analyze the impact and outcomes of early COVID-19 pandemic on liver transplantation(LT)for hepatocellular carcinoma(HCC)in the United *** WHO declared COVID-19 as a pandemic on March 11,*** retrospectively analyzed data from the United Network for Organ Sharing(UNOS)database regarding adult LT with confirmed HCC on explant in 2019 and *** defined pre-COVID period from March 11 to September 11,2019,and early-COVID period as from March 11 to September 11,*** Overall,23.5%fewer LT for HCC were performed during the COVID period(518 vs 675,P<0.05).This decrease was most pronounced in the months of March-April 2020 with a rebound in numbers seen from May-July *** LT recipients for HCC,concurrent diagnosis of non-alcoholic steatohepatitis significantly increased(23 vs 16%)and alcoholic liver disease(ALD)significantly decreased(18 vs 22%)during the COVID *** age,gender,BMI,and MELD score were statistically similar between two groups,while waiting list time decreased during the COVID period(279 days vs 300 days,P=0.041).Among pathological characteristics of HCC,vascular invasion was more prominent during COVID period(P<0.01),while other features were the *** the donor age and other characteristics remained same,the distance between donor and recipient hospitals was significantly increased(P<0.01)and donor risk index was significantly higher(1.68 vs 1.59,P<0.01)during COVID *** outcomes,90-day overall and graft survival were the same,but 180-day overall and graft were significantly inferior during COVID period(94.7 vs 97.0%,P=0.048).On multivariable Coxhazard regression analysis,COVID period emerged as a significant risk factor of post-transplant mortality(Hazard ratio 1.85;95%CI:1.28-2.68,P=0.001).CONCLUSION Durin

关键词： Liver transplantation Hepatocellular carcinoma COVID-19 Mortality Graft failure United Network for Organ Sharing database