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Micropenis Associated or Not with Cryptorchidism in the Endocrinology Department of Yopougon University Hospital in Ivory Coast: Epidemiological, Clinical, Paraclinical and Therapeutic Aspects

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Open Journal of Endocrine and Metabolic Diseases 2024年第3期14卷 75-85页

作者： Adélaïde Hue kossi kodjo Michèle Fotso Jacko Abodo Department of Endocrinology Diabetology at Yopougon University Hospital Abidjan Ivory Coast Internal Medicine and Endocrinology Department of Sylvanus Olympio University Hospital Lomé Togo

Background: Congenital malformations such as micropenis and cryptorchidism do not have immediate dramatic consequences. However, the diagnosis is often unknown at birth, and therefore late. In Ivory Coast, there are few studies on cryptorchidism and micropenis. We conducted this study to identify the epidemiological, clinical, etiological and therapeutic characteristics of the micropenis associated or not with cryptorchidism at Yopougon University Hospital. Methods: We conducted a retrospective descriptive study in the Department of Endocrinology-Diabetology of the Yopougon University Hospital carried out over 13 years from January 2005 to December 2018. All patients were included regardless of the presence of a micropenis associated or not with cryptorchidism in the clinical or paraclinical examination. Results: A total of 14 micropenis were reported associated in 6 cases with cryptorchidism. It was unilateral cryptorchidism in 4 patients or 66.66% of cases. The average age of affected patients was 21.32 years with extremes ranging from 10 months to 48 years. The reason for consultation was micropenis in 12 out of 14 cases or 85.75%. The associated signs apart from cryptorchidism were obesity in 42.86% of cases, gynecomastia in 35.71% of cases. The aetiology was dominated by idiopathic causes. Treatment with testosterone enanthate was more effective in pre-pubertal children than in adults. Conclusion: The diagnosis of micropenis associated or not with cryptorchidism is late because of the frustrations, taboos and psycho-social states that it causes. However, drug treatment is effective when treatment is started early.

关键词： Micropenis Cryptorchidism Hospital Environment Ivory Coast

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Hyperprolactinemia in Hospitals in Lomé: Diagnostic and Therapeutic Aspects

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Open Journal of Internal Medicine 2024年第1期14卷 43-52页

作者： Tchamdja Toyi Djalogue Lihanimpo kodjo kossi Ganu Koudjo Kaaga Laconi Yéba Mossi Komi Edem M’bortché B. kodjo Djibril Mohaman Awalou Balaka Abago Internal Medicine Departement University de Kara Kara Togo Internal Medicine Departement Université of Lomé Lomé Togo

Introduction. Hyperprolactinemia represents a supraphysiological secretion of prolactin. In clinical practice, it is the most frequently encountered anterior pituitary disorder. However, its real prevalence is little known in Africa. The purpose of this study is to list all cases of hyperprolactinemia over the past four years and to make an inventory of the various etiologies found and their management. Methodology. This is a cross-sectional descriptive study on the files of patients who came for consultation in the internal medicine and endocrinology department with hyperprolactinemia retrospectively collected from January 2017 to December 2020. Included were patients followed or whose the diagnosis of hyperprolactinemia was established in endocrinological consultation during the study period. Results. This study recorded 26 cases of hyperprolactinemia. The female sex represented 73.08% (sex ratio M/F 0.37) and the average age was 33.92 years. The 40 - 50 age group was the most represented with 30.77%. In women, galactorrhea accounted for 73.07%, amenorrhea 57.69% of clinical pictures and infertility 23.08%. In men, infertility accounted for 7.69% of presentations, gynecomastia 11.54% and erectile dysfunction 15.38%. The duration of evolution of the signs was 4 months in 23.08% of the patients. The mean prolactinemia was 702.58 ng/ml. CT was performed in 80.85% of patients. The main etiologies were pituitary adenomas (77%). All our patients were treated with dopaminergic agonists. Cabergoline was prescribed in 77% of patients. The evolution was favorable in 96.25% of patients. Conclusion. Hyperprolactinemia is a pathology that exists in our regions. The main etiology remains pituitary adenomas and treatment with cabergoline.

关键词： Hyperprolactinemia Hospital Environment CHU SO Togo

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Compliance with Oral Anti-Diabetic Treatment in Lome

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Open Journal of Internal Medicine 2024年第1期14卷 53-63页

作者： Tchamdja Toyi Djalogue Lihanimpo kodjo kossi Kaaga Laconi Yéba Mossi Komi Edem M’bortché B. kodjo Ehon Ata Edem Djibril Mohaman Awalou Balaka Abago Internal Medicine Departement Université de Kara Kara Togo Internal Medicine Departement Université de Lomé Lomé Togo

Objective: The objective of this study was to assess adherence to antidiabetic therapy in type II diabetic patients and factors associated with Lomé. Method: This was a descriptive observational study conducted among diabetics in diabetes care centers from May 1, 2020 to October 1, 2020, for a period of 6 months. Results: A total of 300 patients were questioned. The mean age was 56.61 years (standard deviation = 11.7). The sex ratio was 0.6. All the patients were on drug treatment, 83.4% of whom were on metformin and 37.5% on Glibenclamide. In 58.3% of the cases, the patients were on dual therapy and 96.2% had an abovenormal glycated hemoglobin value. There was a medication adherence problem with poor adherence in 30.7%. Being aged 50 and over (ORC = 1.78, p = 0.048), playing sports (ORR = 1.87, p = 0.046), have reaching a higher level of education (ORR = 5.78, p = 0.005) significantly increased the chances of patients having a good/minimal problem of adherence. Conclusion: Diabetes affects in Togo, more women than men with a predominance of those aged 50 and over. Adherence to therapy remains a challenge.

关键词： Type II Diabetes Metformin Compliance Associated Factors

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Micropenis Associated or Not with Cryptorchidism in the Endocrinology Department of Yopougon University Hospital in Ivory Coast: Epidemiological,Clinical, Paraclinical and Therapeutic Aspects

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Open Journal of Endocrine and Metabolic Diseases（内分泌与新陈代谢疾病期刊） 2024年第3期 75页

作者： Adélaïde Hue kossi kodjo Michèle Fotso Jacko Abodo

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Compliance with Oral Anti-Diabetic Treatment in Lome

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Open Journal of Internal Medicine（内科学期刊） 2024年第1期 53页

作者： Tchamdja Toyi Djalogue Lihanimpo kodjo kossi Kaaga Laconi Yéba Mossi Komi Edem M’bortché B.kodjo Ehon Ata Edem Djibril Mohaman Awalou Balaka Abago

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Hyperprolactinemia in Hospitals in Lomé: Diagnostic and Therapeutic Aspects

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Open Journal of Internal Medicine（内科学期刊） 2024年第1期 43页

作者： Tchamdja Toyi Djalogue Lihanimpo kodjo kossi Ganu Koudjo Kaaga Laconi Yéba Mossi Komi Edem M’bortché B.kodjo Djibril Mohaman Awalou Balaka Abago

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Epidemiological, Clinical and Evolutive Profile of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in Togo

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Open Journal of Nephrology 2018年第4期8卷 117-123页

作者： Tsevi Yawovi Mawufemo Amekoudi Eyram Yoan Djagadou kodjo Agbeko Sabi kossi Akomola Nemi Komi Dzidzonu kodjo kossi Tona Komlan Georges Dolaama Badomta Attisso Eugene Hadabia D’daah Djibril Mohaman Awalou Department of Nephrology and Hemodialysis of the Sylvanus Olympio University Hospital of Lomé University of Lome Lomé Togo Internal Medicine Department of the Sylvanus Olympio University Hospital in Lome University of Lome Lomé Togo

Objective: To describe the epidemiological, clinical and evolutionary profile of ADPKD in Togo. Methods: A retrospective descriptive transversal study over a period of 8 years (2011-2018) which focused on the analysis of patients’ records diagnosed with ADPKD. The diagnosis of ADPKD was retained on the basis of the ultrasound criteria of PEI. Results: During the study period, 27 patients had polycystic kidney disease with a prevalence of 0.87%. The average age was 51.6 ± 16.4 years. There were 10 men (37%) and 17 women (63%), a sex ratio (M/F) of 0.58. The concept of family cystic kidney disease was found in 6 (22.2%) patients. The clinical presentations were dominated by arterial high blood pressure, abdominal pain and abdominal mass respectively in 77%, 63% and 63% of cases. Five patients (18.5%) had a glomerular filtration rate (GFR) greater than 90 ml/min, 17 (62.9%) had a GFR Conclusion: ADPKD is common in our department. It appears to be associated with a high rate of chronic renal failure.

关键词： Polycystic Kidney Disease CKD Togo

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Doppler Ultrasound Abnormalities of the Lower Limbs in Patients with Diabetic Foot at the Yopougon University Hospital in Ivory Coast

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Open Journal of Endocrine and Metabolic Diseases 2022年第5期12卷 113-121页

作者： kossi kodjo Mamadou Mansour Diallo Alpha Mamadou Diallo Koffi Pierre Dago Adelaide Hue Assita Yao Abodo Jacko Adrien Lokrou Department of Endocrinology and Diabetes Yopougon University Hospital Abidjan Ivory Coast Department of Internal Medicine and Endocrinology Sylvanus Olympio University Hospital of Lomé Faculty of Health Sciences University of Lomé Lomé Togo Department of Endocrinology Diabetology Donka Hospital University Hospital of Conakry Conakry Guinea

Background: Diabetic foot is a frequent complication of diabetes, of multifactorial origin, associating nervous and/or circulatory disorders to which infection is often added. Its care is multidisciplinary and requires coordination between different actors. In this context, arterial doppler ultrasound is essential in the diagnosis of diabetic arteriopathy and participates in therapeutic decision-making. The aim of this study was to describe the abnormalities found on Doppler ultrasonography of patients hospitalized for the diabetic foot in the Ivory Coast. Methods: We conducted a retrospective descriptive study including 235 patients hospitalized for the diabetic foot in the Endocrinology department of the Yopougon University Hospital from February 2002 to December 2015. All records of patients who performed arterial Doppler ultrasound of the lower limbs were selected and the various abnormalities were described. Results: The sex ratio (M/F) was 1.1 (124 men to 111 women). The predominant age group was 61.2 years. Type 2 diabetes was found in 97.4% of cases. The average evolution of diabetes was 8.9 years with extremes of 1 and 32 years. Wet gangrene was the most common type of lesion found in 75.8% of cases. On ultrasonography, 98.7% of the patients had an arterial abnormality of the lower limbs. It was bilateral in 62.2% of cases, dominated by atheromatous overloads and mediacalcosis in 46.4% and 43.8% of cases, respectively. Arterial stenosis was lesions hemodynamically found in 76.3% of cases and arterial occlusions in 32.7% of cases. The amputation rate was 72.7%. Conclusion: This study shows the high frequency of arterial abnormalities in patients with the diabetic foot with a predominantly distal involvement. Arterial Doppler ultrasound of the lower limbs remains an essential tool in the care of diabetic foot. This easily accessible, non-invasive examination has a key role in therapeutic decision-making.

关键词： Diabetes Arterial Doppler Ultrasound Arteriopathy Ivory Coast

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Renal Risk among Diabetic Patients in Togo

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Open Journal of Nephrology 2022年第3期12卷 249-261页

作者： kodjo kossi Tsevi Yawovi Mawufemo Dolaama Badomta Tona Komlan Georges Balaka Abago Yao K. Hubert Gnionsahe Daze Apollinaire Centre Hospitalier Universitaire Sylvanus Olympio Lome Togo Centre Hospitalier Universitaire de Treichville Abidjan Cote d’Ivoire Centre Nationale de Prévention et de Traitement de l’Insuffisance Renal Abidjan Cote d’Ivoire

Background: Diabetic patients have risk of kidney disease. The aim of this study was to assess the level of renal risk in our study population and to identify the associated predictive factors. Methods: It was a descriptive and analytical cross-sectional study carried out over 5 years (January 1, 2016 to December 31, 2020). All patients were included regardless of the duration of diabetes and having achieved at least one serum creatinine and at least two (2) proteinuria in the 24 hours over a period of at least three months. The level of renal risk was assessed using the KDIGO 2012 classification. Results: A total of 320 patient medical files were retained. The sex ratio M/F was 1.2. The average age was 57.2 ± 11.8 years. Hypertension was the most common comorbidity (84.4%). Diabetic nephropathy was found in 177 patients, a frequency of 42.8%. The very significant renal risk was found in 174 patients (54.4%). In multivariate logistic regression, the risk factors significantly associated with renal risk were: Male sex (OR = 2.50;95% CI = 1.29 - 4.84, p-value = 0.006);microangiopathy (OR = 5.54;95% CI = 1.82 - 16.85 p = 0.002) and beta-blockers (OR = 5.64;95% CI = 1.04 - 30.53 p = 0.004). The Oral Antidiabetes (OR = 0.23;95% CI = 0.10 - 0.55, p = 0.001), the blockers of Renin-Angiotensin system (OR = 0.58;95% CI = 0.41 - 0.90, p = 0.040) and the average socioeconomic level (OR = 0.50;95% CI = 0.25 - 0.98, p = 0.044) were rather the protective factors.

关键词： Diabetic Kidney Disease Kidney Risk Togo

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Knowledge, Attitudes and Practices of Diabetic Patients on Ocular Complications of Diabetes in Lomé(Togo)

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Open Journal of Endocrine and Metabolic Diseases 2022年第9期12卷 197-210页

作者： Kokou Vonor kossi kodjo Kwam Dodji Godwin Yaovi Tété Koffi Didier Ayéna Méba Banla Komi Patrice Balo Department of Ophthalmology Regional Hospital of Kara Kara Togo Departement of Ophthalmology Faculty of Health Sciences University of Lomé Togo Department of Internal Medicine and Endocrinology Sylvanus Olympio University Hospital of Lomé Lomé Togo

Introduction: The frequency and severity of eye complications from diabetes make patient education essential, which is the basis for adequate management. What is the level of education of diabetic patients in Lomé? The aim of this study was to assess the knowledge, attitudes and practices of diabetic patients on the ocular complications of diabetes in Lomé. Methods: We conducted a cross-sectional study by surveys on diabetic patients from April 1 to June 31, 2020, in 6 diabetes management centers in Lomé. The correct response rate was established for each component. Knowledge: poor (≤ 50%), low (50% - 65%), medium (65% - 85%) and good (≥ 85%). Attitudes: harmful (≤ 50%), erroneous (50% - 65%), approximate (65% - 85%) and fair (≥ 85%). Practice: harmful (≤ 50%), inadequate (50% - 65%) and adequate (>65%). Results: Over the study period, 150 patients were enrolled. The mean age was 56.98 ± 13.37 years with a sex ratio of 1.1 (79 men/71 women). The overall level of knowledge was insufficient (50.6%) with 65.5% for general knowledge about diabetes and 35.8% for ocular complications of diabetes. Attitudes were approximate (68.7%). In the case of hyperglycemia, 31.3% of patients would confide in a diabetologist and 22.0% in a general practitioner. If decrease in vision, 84.3% of patients would contact the ophthalmologist. The level of practice was harmful (20.4%). For diabetic follow-up, 36.7% of patients have already seen an ophthalmologist, 41.3% have performed a fundus examination, 17.3% retinal angiography, 4% laser retinal photocoagulation and 2.7% intravitreal injection (IVT). An awareness session on the ocular complications of diabetes was followed by 52.7% of patients and 50.7% of patients followed a therapeutic education session. Conclusion: This study has shown that the level of knowledge was poor, attitudes approximate and practices harmful. It is therefore important to raise awareness about diabetes and its ocular complications with the aim to change behavior.

关键词： Knowledge Attitudes Practices Eye Complications Diabetes Lomé

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