检索结果-南通市图书馆

流程工业 2013年第1期 42-43页

作者： jens-Peter Kraus klaus Peter Mont Kumpugdee Vollrath 柏林Beuth枝术学院柏林Libel工程技术公司

在某一合作项目中，Beuth技术学院研发设计了一台新型的、利用喷雾技术生产较大面积薄膜的实验室设备。这一设备使得在实验室辊涂机外，通过重复生产对保护膜的形成和性能进行检验成为可能。本文介绍了这一设备的结构设计和首次测试的... 详细信息

在某一合作项目中，Beuth技术学院研发设计了一台新型的、利用喷雾技术生产较大面积薄膜的实验室设备。这一设备使得在实验室辊涂机外，通过重复生产对保护膜的形成和性能进行检验成为可能。本文介绍了这一设备的结构设计和首次测试的结果。

关键词：实验室设备制膜压铸喷膜喷雾技术结构设计合作项目辊涂机

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

杂砂岩碱集料反应特征

硅酸盐学报 2008年第10期36卷 1385-1389页

作者：莫祥银景颖杰 HUNGER klaus-jurgen 康彩荣沈健南京师范大学分析测试中心＆江苏省生物功能材料重点实验室南京210097 Faculty for Architecture Civil Engineeringnd Urban Planning Brandenburg University of Technology Cottbus Cottbus 03046 Germany 南京工业大学材料科学与工程学院南京210009

杂砂岩集料所含的石英组分是引起碱集料反应的主要活性来源,研究该集料中的石英溶出及其在碱溶液中的行为特征,结果发现:石英颗粒尺寸和相应的硅溶出速度之间存在着一定的相关性,即:石英颗粒尺寸越小,其比表面积越大,同等条件下相应的... 详细信息

杂砂岩集料所含的石英组分是引起碱集料反应的主要活性来源,研究该集料中的石英溶出及其在碱溶液中的行为特征,结果发现:石英颗粒尺寸和相应的硅溶出速度之间存在着一定的相关性,即:石英颗粒尺寸越小,其比表面积越大,同等条件下相应的硅溶出速度越大;石英颗粒的结构特征变化规律与杂砂岩试样本身的碱活性大小之间不存在相关性。集料中的铝主要来源于γ-Al2O3纳米相、黑云母和白云母,其对溶液中硅溶出的影响机理不同。集料中的铝溶出生成铝硅酸盐从而引起溶液中溶出硅含量的降低,砂浆或混凝土碱集料反应膨胀率的大小与溶液中所谓的"自由硅"含量有关,即"自由硅"含量越大,同等条件下的碱集料反应膨胀越大。这些相关性对于实际工程应用非常重要,由此可望建立评价杂砂岩碱活性敏感性的直接测试方法。研究还发现通过添加高铝粉可抑制碱集料反应产生的膨胀。

关键词：碱集料反应砂岩铝溶出过程化学测试方法

在线全文

学校读者我要写书评

暂无评论

先进机身结构和材料设计

航空制造技术 2009年第15期52卷 26-29页

作者： jens Hinrichsen Paul Marks klaus Drechsler Leslie Cohen 德国航天咨询责任有限公司美国雅奇国际有限公司德国斯图加特大学飞机设计研究所美国HITCO碳复合材料公司

由于大型商用飞机机身结构的复杂性,其碳纤维复合材料部件的设计、制造和取证都不能借用现有的制造维修基本经验。碳纤维复合材料机身壁板超越了现代化金属技术,对应力应变的保守限制要求必须保证将具有损伤容限的机身结构交付到航空公... 详细信息

由于大型商用飞机机身结构的复杂性,其碳纤维复合材料部件的设计、制造和取证都不能借用现有的制造维修基本经验。碳纤维复合材料机身壁板超越了现代化金属技术,对应力应变的保守限制要求必须保证将具有损伤容限的机身结构交付到航空公司。这样,碳纤维复合材料壁板技术的应用至少限制了新飞机家族第一代成员的重量。

关键词：机身结构材料设计碳纤维复合材料复合材料部件商用飞机航空公司损伤容限应力应变

Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology

在线全文

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2011年第7期17卷 922-925页

作者： Mikkel Malham SΦren Peter jΦrgensen Peter Ott jΦrgen Agnholt Hendrik Vilstrup Mette Borre jens F Dahlerup Department of Medicine V (Hepatology and Gastroenterology) Aarhus University Hospital

AIM: To examine the vitamin D status in patients with alcoholic cirrhosis compared to those with primary biliary cirrhosis. METHODS: Our retrospective case series comprised 89 patients with alcoholic cirrhosis and 34 patients with primary biliary cirrhosis who visited our outpatient clinic in 2005 and underwent a serum vitamin D status assessment. RESULTS: Among the patients with alcoholic cirrhosis, 85% had serum vitamin D levels below 50 nmol/L and 55% had levels below 25 nmol/L, as compared to 60% and 16% of the patients with primary biliary cirrhosis, respectively (P < 0.001). In both groups, serum vitamin D levels decreased with increasing liver disease severity, as determined by the Child-Pugh score. CONCLUSION: Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology, with lower levels of vitamin D in alcoholic cirrhosis than in primary biliary cirrhosis.

关键词： Alcoholic liver cirrhosis Child-Pugh score Primary biliary cirrhosis Vitamin D deficiency

互补音系学——对一个对话声学资料库进行标记的理论框架

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

当代语言学 1995年第1期 34-36页

作者： klaus j.Kohler 曹剑芬中国社会科学院语言研究所

1.科学上的互补性概念 1927年左右,Niels Bohr将互补性的见解引入了物理学。他是出于这样一种考虑,即一些古典的物理学概念已不足以胜任对核子物理现象的描写。例如,由于不同的实验设计,光在一种情况下以“波场”的面目出现,而在另一种... 详细信息

1.科学上的互补性概念 1927年左右,Niels Bohr将互补性的见解引入了物理学。他是出于这样一种考虑,即一些古典的物理学概念已不足以胜任对核子物理现象的描写。例如,由于不同的实验设计,光在一种情况下以“波场”的面目出现,而在另一种情况下则作为一种“粒子云”出现。按照古典物理学的概念,这两个方面是互相排斥的。

关键词：音系学资料库行标记物理学声学超音段音段音位国际音标标音典型形式

SNOWY COTYLEDON 2 Promotes Chloroplast Development and Has a Role in Leaf Variegation in Both Lotus japonicus and Arabidopsis thaliana

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2017年第5期10卷 721-734页

作者： Nicola Zagari Omar Sandoval-lbanez Niels Sandal junyi Su Manuel Rodriguez-Concepcion jens Stougaard Mathias Pribil Dario Leister Pablo Pulido Plant Molecular Biology Department of Biology I Ludwig-Maximilians-Universitat Munchen 82152 Planegg-Martinsried Germany Copenhagen Plant Science Center University of Copenhagen 1871 Frederiksberg C Denmark Research and Innovation Center Fondazione Edmund Mach via E. Mach 1 38010 San Michele all'Adige Italy Centre for Carbohydrate Recognition and Signalling Department of Molecular Biology and Genetics Aarhus University Gustav Wieds Vej 10 8000 Aarhus C Denmark Centre for Research in Agricultural Genomics (CRAG) CSIC-IRTA-UAB-UB Campus UAB Bellaterra 08193 Barcelona Spain

Plants contain various factors that transiently interact with subunits or intermediates of the thylakoid multiprotein complexes, promoting their stable association and integration. Hence, assembly factors are essential for chloroplast development and the transition from heterotrophic to phototrophic growth. Snowy cotyledon 2 （SCO2） is a DNAj-like protein involved in thylakoid membrane biogenesis and interacts with the light-harvesting chlorophyll-binding protein LHCBI. In Arabidopsis thaliana, SCO2 function was previ- ously reported to be restricted to cotyledons. Here we show that disruption of SC02 in Lotus japonicus results not only in paler cotyledons but also in variegated true leaves. Furthermore, smaller and pale- green true leaves can also be observed in A. thaliana sco2 （atsco2） mutants under short-day conditions. In both species, SCO2 is required for proper accumulation of PSlI-LHCll complexes. In contrast to other variegated mutants, inhibition of chloroplastic translation strongly affects L. japonicus sco2 mutant devel- opment and fails to suppress their variegated phenotype. Moreover, inactivation of the suppressor of variegation AtClpR1 in the atsco2 background results in an additive double-mutant phenotype with variegated true leaves. Taken together, our results indicate that SCO2 plays a distinct role in PSll assembly or repair and constitutes a novel factor involved in leaf variegation.

关键词： SCO2 DNAj-like photosynthesis assembly factor variegation chloroplast development

Brain changes in diabetes mellitus patients withgastrointestinal symptoms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Diabetes 2016年第2期7卷 14-26页

作者： Anne M Drewes Eirik Søfteland Georg Dimcevski Adam D Farmer Christina Brock jens B Frøkjær klaus Krogh Asbjørn M Drewes Department of Medicine Haukeland University Hospital5021 BergenNorway Centre for Digestive Diseases Blizard Institute of Cell and Molecular ScienceWingate Institute of NeurogastroenterologyBarts and the London School of Medicine and DentistryQueen Mary University of LondonLondon E1 2AJUnited Kingdom Department of Gastroenterology University Hospitals of North MidlandsStoke on TrentStraffordshire ST4 6QGUnited Kingdom Mech-Sense Department of Gastroenterology and Hepatology and Clinical InstituteAalborg University Hospital9100 AalborgDenmark Department of Radiology Aalborg University Hospital9100 AalborgDenmark Neurogastroenterology Unit Department of Hepatology and GastroenterologyAarhus University Hospital8000 AarhusDenmark

Diabetes mellitus is a common disease and its prevalence is increasing worldwide. In various studies up to 30%-70% of patients present dysfunction and complications related to the gut. To date several clinical studies have demonstrated that autonomic nervous system neuropathy and generalized neuropathy of the central nervous system(CNS) may play a major role. This systematic review provides an overview of the neurodegenerative changes that occur as a consequence of diabetes with a focus on the CNS changes and gastrointestinal(GI) dysfunction. Animal models where diabetes was induced experimentally support that the disease induces changes in CNS. Recent investigations with electroencephalography and functional brain imaging in patients with diabetes confirm these structural and functional brain changes. Encephalographic studies demonstrated that altered insular processing of sensory stimuli seems to be a key player in symptom generation. In fact one study indicated that the more GI symptoms the patients experienced, the deeper the insular electrical source was located. The electroencephalography was often used in combination with quantitative sensory testingmainly showing hyposensitivity to stimulation of GI organs. Imaging studies on patients with diabetes and GI symptoms mainly showed microstructural changes,especially in brain areas involved in visceral sensory processing. As the electrophysiological and imaging changes were associated with GI and autonomic symptoms they may represent a future therapeutic target for treating diabetics either pharmacologically or with neuromodulation.

关键词： Diabetes mellitus Gastrointestinal Electroencephalogram Magnetic resonance imaging Brain

Feeding Bacillus-based probiotics to gestating and lactating sows is an efficient method for improving immunity,gut functional status and biofilm formation by probiotic bacteria in piglets at weaning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Nutrition 2023年第2期13卷 361-372页

作者： PawełKonieczka Karolina Ferenc jens Njørgensen Lea HBHansen Romuald Zabielski jarosław Olszewski Zdzisław Gajewski Magdalena Mazur-Kusnirek Dominika Szkopek Natalia Szyrynska Krzysztof Lipinski Department of Poultry Science University of Warmia and Mazury in OlsztynOlsztynPoland Department of Animal Nutrition The Kielanowski Institute of Animal Physiology and Nutrition Polish Academy of SciencesJabłonnaPoland Center for Translational Medicine Warsaw University of Life SciencesWarszawaPoland Chr.Hansen A/S Animal Health and NutritionHoersholmDenmark Department of Animal Nutrition and Feed Science University of Warmia and Mazury in OlsztynOlsztynPoland Department of Histology and Embryology Faculty of Veterinary MedicineUniversity of Warmia and Mazury in OlsztynOlsztynPoland

The effects of dietary probiotic supplementation with viable Bacillus subtilis and Bacillus amyloliquefaciens spores on sow performance,immunity,gut functional status and biofilm formation by probiotic bacteria in piglets at weaning were ***-six sows reared in a continuous farrowing system for one full cycle were fed gestation diets during the first 90 d of pregnancy and lactation diets until the end of *** sows were fed a basal diet without probiotics(control;n=48)or a diet supplemented with viable spores(1.1×10^(9)CFU/kg of feed)(probiotic;n=48).At 7 d of age,sucking piglets(n=12/group)were provided prestarter creep feed until weaning at 28 d of *** piglets in the probiotic group were supplemented with the same probiotic and dosage as their *** and colostrum collected from sows and ileal tissues collected from piglets on the day of weaning were used for *** increased the weight of piglets(P=0.077),improved the weaning weight(P=0.039)and increased both the total creep feed consumption(P=0.027)and litter gain(P=0.011).Probiotics also improved the faecal score in the second(P=0.013)week of *** immunoglobulin G(IgG)concentrations in sow blood at farrowing and the IgM concentrations in piglet blood at weaning were higher in the probiotic group than in the control group(P=0.046).The piglets from the probiotic-treated sows showed a higher IgM concentration in the ileal mucosa(P=0.050)and a lower IgG concentration in the ileal mucosa(P=0.021)compared with the piglets from control *** probiotic-treated piglets had a thicker ileal mucosa(P=0.012)due to the presence of longer villi and larger Peyer's patches(P<0.001).*** and *** were detected in the probiotic-treated piglets but not the control piglets;these bacteria were present in the digesta and villus structures and formed structures resembling ***,Bacillus-based probiotic supplementation improves the health indices of sows

关键词： Probiotic Gut function Immune status Biofilm Piglet Sow

IPM Strategies and Their Dilemmas Including an Introduction to www. ***

在线全文

学校读者我要写书评

暂无评论

journal of Integrative Agriculture 2014年第2期13卷 265-281页

作者： Lise Nistrup jφrgensen Mogens Stφvring Hovmφller jens Grφnbk Hansen Poul Lassen Bill Clark Rosemary Bayles Bernd Rodemann Kerstin Flath Margot jahn Tomas Goral jerzy Czembor j Philip Cheyron Claude Maumene Claude De Pope Rita Ban Ghita Cordsen Nielsen Gunilla Berg Depar tment of Agroecology Aarhus UniversityFlakkebjergFors?gsvej 1Slagelse 4200Denmark Aarhus University FoulumBlichers Allé 20Tjele 8830Denmark NIAB/TAG Huntingdon RoadCambridge CB3 0LEUnited Kingdom julius Kuehn Institute Messerweg 11Braunsweig 38104Germany julius Kuehn Institute Stahndorfer Damm 81Kleinmachnow14532Germany Plant Breeding and Acclimatization Institute IHAR-PIB RadzikowBlonie 05-870Poland Arvalis du Vegetal Boigneville 91720France Institut National de la Recherche Agronomique (INRA) Thiverval Grinon 78850France Szent István University Pater K.Street 1Godollo 2100Hungary Knowledge Centre for Agriculture SkejbyAarhus N 8200Denmark Swedish Board of Agriculture Plant Protection CentreAlnarp 23053Sweden

Information about disease management in winter wheat （Triticum aestiva） in eight European countries was collated and analysed by scientists and extension workers within the European Network for the Durable Exploitation of Crop Protection Strategies （ENDURE）. This included information about specific disease thresholds, decision support systems, host varieties, disease prevalence and pathogen virulence. Major differences in disease prevalence and economic importance were observed. Septoria tritici blotch （Mycosphaerella graminicola） was recognized as the most yield reducing disease in countries with intensive wheat production, but also rust diseases （Puccinia striiformis and Puccinia triticina）, powdery mildew （Blumeria graminis） and Fusarium head blight （Fusarium spp.） were seen as serious disease problems. Examples of current integrated pest management （IPM） strategies in different countries have been reported. Disease management and fungicide use patterns showed major differences, with an average input equivalent to 2.3 full dose rates （TFI） in the UK and a TFI of 0.6 in Denmark. These differences are most likely due to a combination of different cropping systems, climatic differences, disease prevalence, and socio-economic factors. The web based information platform *** was used for dissemination of information and results including information on control thresholds, cultural practices which can influence disease attack, fungicide efficacy, fungicide resistance, and pathogen virulence, which are all elements supporting 1PM for disease control in wheat. The platform is open to all users. The target groups of EuroWheat information are researchers, advisors, breeders, and similar partners dealing with disease management in wheat.

关键词： winter wheat IPM fungicides diseases cultural methods

Adjuvant effects of different TLR agonists on the induction of allergen-specific Th2 responses

在线全文

学校读者我要写书评

暂无评论

Open journal of Immunology 2012年第1期2卷 17-24页

作者： Matthias j. Duechs james E. Brunt Florian Gantner klaus j. Erb Respiratory Diseases Research Boehringer Ingelheim Pharma GmbH & Co. KG Biberach an der Riss Germany

Currently different Toll-like receptor (TLR) agonists are tested in humans for their ability to enhance the efficacy of specific immunotherapy (SIT). Recent clinical data suggest that this may be achieved by increasing allergen-specific Th1 responses. However, it is not clear which TLR agonist is best suited to be used in combination with SIT. We tested the ability of five TLR agonists, LTA, poly(I:C), LPS, R848, and CpG-ODN, activating TLR2, 3, 4, 7, and 9, to induce allergen-specific Th1 and suppress allergen-specific Th2 responses in a preclinical setting. Mice were immunized by intraperitoneal injection of ovalbumin (OVA)/Al(OH)3 together with different doses (0.0025, 0.025, 0.25, and 2.5 mg/kg) of agonists followed by two OVA aerosol challenges. The results of these experiments showed, that the suppression of allergen-specific Th2 responses and the induction of Th1 responses dependedon the dose and the agonists used. All TLR agonists increased allergen-specific IgG2a, and with the exception of poly(I:C), reduced allergen-specific IgE levels in the serum. Allergic cutaneous anaphylaxis was also suppressed in mice when LPS or CpG was given together with OVA/alum. The strongest Th1 responses were induced by CpG and poly(I:C), characterized by the presence of IFN-g in the BAL and the highest OVA-specific IgG2a levels in the serum. This study suggests that the TLR9 agonist CpG-ODN and TLR4 agonist LPS have the strongest suppressive effects on the development of aller-gen-specific Th2 responses in mice and CpG-ODN induces the strongest allergen-specific Th1 responses. Therefore these two TLR agonists may be good candidates to combine with allergen in novel SIT formulations in humans.

关键词： Asthma TLR-Agonists Innate-Inflammation Inhibition