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世界核心医学期刊文摘（胃肠病学分册） 2006年第3期2卷 55-56页

作者： Ryozawa S. kitoh h. Gondo T. 程妍 Department of Gastroenterology and h.patology Yamaguchi University School of Medicine 1-1-1 Minamikogushi Ube 755-8505 Japan

Background: Endoscopic ultrasonograph.-guided fine-nee-dle aspiration biopsy (EUS-FNAB) h.s come into widespread use, mainly in Western countries, as an efficient and safe meth.d for th. cytologic or h.stologic diagnosis of pancreatic cancer. h.wever, it still h.s received relatively little attention in Japan. To evaluate th. clinical status of EUS-FNAB in Japan, we retrospectively analyzed th. results with.regard to th. ability of EUS-FNAB to diagnose pancreatic cancer, as well as its safety. Meth.ds: A total of 52 patients (37 male, 15 female; mean age, 62.5 years; range, 33-85 years) with.focal pancreatic lesions underwent EUS-FNAB at our group of h.spitals in one region of Japan. Final diagnosis was confirmed by h.stologic examination of surgical specimens or clinical follow-up. Results: Th. final diagnoses were malignant tumors in 32 patients and benign ones in 20. Insertion of th. needle into th. lesion was successful in 50 of th. 52 patients (96.2%). Adequate specimens were obtained by EUS-FNAB from 47 of th. 50 pancreatic lesions (94.0%). With.five false-negative and no false-positive results, th. accuracy, sensitivity, specificity, and positive and negative predictive values were 89.4%, 82.1%, 100%, 100%, and 79.2%, respectively. No complications occurred. Conclusions: EUS-FNAB is an efficient and safe meth.d for th. h.stologic diagnosis of pancreatic cancer. It sh.uld be considered as one of th. indispensable modalities for th. h.stological diagnosis of pancreatic cancer in Japan, as it is in Western countries.

关键词：细针抽吸活检超声内镜组织学检查良性肿瘤患者组织学诊断活检标本活组织检查确诊依据假阴性

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