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硅酸盐学报 1994年第5期22卷 427-433页

作者：孙雨南 kind.,ds 北京理工大学工程光学系

研制了几种由离子交换形成梯度折射率的铝－硼酸盐玻璃。通过Ｌｉ￣（＋）和Ｎａ￣（＋）离子交换分别获得了了负轴向折射率梯度。折射率差达０．０３，梯度Ａｂｂｅ数大于１００。

关键词：离子交换梯度折射率硼酸盐玻璃

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实时显示生成器

飞行器测控技术 1995年第1期14卷 74-78,73页

作者： kind.,ED 彭利文

伯利恒钢铁公司伯恩斯港厂为改进冷轧薄钢板表面质量的炼？…

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国外钢铁钒钛 1996年第2期9卷 103-113,123页

作者： kind.,DH 郭新春伯利恒钢铁公司

Deoxyelephantopin induces ROS-mediated autophagy and apoptosis in human colorectal cancer in vitro and in vivo

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Asian Pacific Journal of Tropical Biomedicine 2020年第3期10卷 120-135页

作者： Chim-Kei Chan kind.Leng Tong Pooi-Fong Wong Habsah Abdul Kadir Biomolecular Research Group Biochemistry ProgramInstitute of Biological SciencesFaculty of ScienceUniversity of Malaya50603 Kuala LumpurMalaysia Department of Pharmacology Faculty of MedicineUniversity of Malaya50603 Kuala LumpurMalaysia

Objective:To systematically map the stepwise events leading to deoxyelephantopin-induced cell death of HCT116 human colorectal cancer cells and evaluate the effectiveness of deoxyelephantopin in ***:HCT116 cells were treated with deoxyelephantopin at various concentrations and time *** was confirmed by the detection of autophagosomes and autophagosomal proteins by electron microscopy and Western blotting assays,respectively,and then validated by siRNA *** addition,apoptosis was confirmed by the detection of apoptosis-related *** intracellular reactive oxygen species(ROS)level was measured using flow *** growth inhibitory effect of deoxyelephantopin was further evaluated in vivo using a mouse xenograft ***:Deoxyelephantopin firstly elevated ROS production,which then triggered autophagic flux with the accumulation of autophagosomal proteins including LC3 A/B,ATG5,and ATG7,followed by the induction of apoptosis via the intrinsic and extrinsic ***-treatment with N-acetyl-L-cysteine,a ROS inhibitor,reversed both apoptosis and *** knockdown of LC3 prevented apoptosis induction which confirmed that deoxyelephantopin induced autophagy-dependent apoptosis in HCT116 *** of ROS also activated apoptosis via the mitogen-activated protein kinases signaling ***,deoxyelephantopin also inhibited the PI3 K/AKT/mTOR pathway,which then released the inhibition of *** vivo study further showed that deoxyelephantopin significantly suppressed the growth of HCT116 subcutaneous xenograft in nude ***:Our findings revealed that deoxyelephantopin elevates oxidative stress and induces ROS-dependent autophagy followed by apoptosis in HCT116 cells via the concerted modulation of multiple signaling *** findings further support the development of deoxyelephantopin as a therapeutic agent for colorectal cancer.

关键词： Deoxyelephantopin Autophagy PI3K mTOR Colorectal cancer MAPK

Current Trends in Tall Building Construction

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Current Trends in Tall Building Construction

分离三分量远震接收函数的多道最大或然性反褶积方法

国际桥梁2004年大会

作者： Steffen kind Prof. Dr.-Ing.University of Applied Sciences Darmstadt Germany Office for Structural Engineering Wiesbaden Germany

＜正＞ Essential tendencies in the international field of tall building construction are shown. The article gives details on the complexity of a variety of requirements originating from esthetics, functionality, economical feasibility and safety, as well as planning, erection, usage （and re-usage） and demolition. On the whole, the tendencies are described as follows: increasing flexibility, filigree full glass facades, integrative planning, improved room climate, modified vibration behaviour, optimised supporting complexes and materials, increased safety requirements.

关键词： tall buildings glass facades room-climate integrative planning vibration structures materials safety.

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地震地质 2004年第3期26卷 416-425页

作者：刘启元 Rainer kind 中国地震局地质研究所地震动力学国家重点实验室 GeoForschung Zentrum Potsdam Telegrafenberg14473 PotsdamGermany

迄今为止 ,广泛应用的分离接收函数方法主要基于单个台站的观测数据 ,并依赖等效震源假定的有效性。当地壳内存在明显的间断面时 ,等效震源假定不适于宽频带地震波形数据 ,接收函数的估计将在不同程度上遭到破坏。解决这个问题的出路在... 详细信息

迄今为止 ,广泛应用的分离接收函数方法主要基于单个台站的观测数据 ,并依赖等效震源假定的有效性。当地壳内存在明显的间断面时 ,等效震源假定不适于宽频带地震波形数据 ,接收函数的估计将在不同程度上遭到破坏。解决这个问题的出路在于避免使用等效震源假定。依据多道最大或然性反褶积原理 ,给出了利用多道观测数据分离接收函数的方法。我们的方法避免了等效震源假定 ,这对于在复杂构造环境条件下改善接收函数的估计具有实际价值。合成地震图的数值检验结果验证了给出的方法。利用该方法 ,我们得到了跨越大别山造山带 ,从江西大冶附近的大箕铺 (30°2 0′N ,1 1 5°0 3′E)到河南兰考附近的崔林 (34°4 0′N ,1 1 4°4 9′E) ,总长度约 5 0 0km的流动地震台阵剖面各台站的三分量接收函数估计。与基于单台数据的接收函数径向分量比较表明。

关键词：分离接收函数地震台站地震波形数据震源反褶积

Pharmacognostic standardization of stems of Thespesia lampas(Cav.)Dalz & Gibs

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Asian Pacific Journal of Tropical Biomedicine 2012年第5期2卷 357-363页

作者： Chumbhale ds Upasani CD Department of Pharmacognosy Amrutvahini College of Pharmacy SNJB'S Shriman Sureshdada Jain College of Pharmacy

Objective:To establish the standardization parameters for complete pharmacoguoslic evaluation of stems of Tlespesia lampas(***)(Cav.) Dalz & Gibs(Malvaceae),an important planl in the Indian system of ***:Morphological,microscopical,physico-chemical evaluations,florescence analysis of *** stems were investigated and preliminary phytochemical analysis,GO-MS analysis and HPTLC fingerprinting were carried out for qualitative phytochemical evaluation of various extracts of stems of ***:Chemomieroscopy revealed the presence of *** grains and calcium oxalate *** evaluation used to detennine numerical slandards showed a result with total ash(9.03± 0.05)%w/w,acid insoluble ash(1.50±0.01)%w/w,water soluble ash(2.51±0.02)%w/w,sulphated ash(7.50+0.01)%w/w,ethanol soluble extractive(0.24±0.02)%w/w,water soluble extractive(0.08 ±0.01)ds, starch,alkaloid,flavonoids and *** phytochemical analysis revealed presence of glycosides,phenolic compounds,tannins,steroids,saponins,flavonoids,carbohydrates and ***-MS analysis showed the presence of fatty acids such as dodecanoic acid, lelraclecanoic acid,n-hexadecanoic acid,9-lelradecenal and HPTLC fingerprinting revealed the presence of β-sitosterol and quercetin in stems of ***:The pharmacognostic standardization of *** is useful towards establishing standards for quality, purity and sample identification.

关键词： Thespesia lampas Stems Pharmacognosy Malvaceae Physicochemical analysis Preliminary phytochemical testing GC-MS analysis Phelloderm Periderm Xylem

Seismic signature of the collision between the east Tibetan escape flow and the Sichuan Basin

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Seismic signature of the collision between the east Tibetan ...

GENERALIZED RAY APPROXIMATE METHOD TO INVERSE MEDIUM PARAMETERS

中国科学院地质与地球物理研究所第十届(2010年度)学术年会

作者： Rainer kind Deutsches GeoForschungsZentrum GFZ Telegrafenberg14473 PotsdamGermany Freie Universitat Berlin Germany

GPS displacement vectors show that the crust in east Tibet is being squeezed in an easterly direction by the northward motion of the Indian plate,and the Sichuan Basin is resisting this stream and redirecting it mainly towards *** Longmen Shan,containing the steepest rise to the high plateau anywhere in Tibet, results from the strong interaction between the east Tibetan escape flow and the rigid Yangtze block (Sichuan Basin),but the kinematics and dynamics of this interaction are still the subject of some *** herein present results from a dense passive-source seismic profile from the Sichuan Basin into eastern Tibet in order to study the deep structure of this collision *** P and S receiver function images we observe a sudden rise of the Lithosphere-Asthenosphere Boundary(LAB) from 120 to 150 km beneath the Sichuan Basin and from 70 to 80 km beneath eastern *** contrast,the depth of the crust-mantle boundary (Moho) increases from 36 to 40 km beneath the Sichuan Basin and from 55 to 60 km beneath eastern Tibet. The 410km discontinuity is depressed below eastern Tibet by about 30 km,although the 660 remains at nearly the same depth throughout the *** these observations,we conclude that the mode of collision that occurs between Tibet and the Sichuan Basin is very different to that found between India and *** southern Tibet,we observe in essence the subduction of the Indian plate,which penetrates northwards for several hundred kilometers under central *** very thin mantle part of the lithosphere beneath eastern Tibet may indicate delamination or removal of the bottom of the lithosphere by hot asthenospheric escape *** process leads to the exceptionally steep topography at the eastern Tibetan margin as a result of gravitational *** view is supported by the very unusual depression of the 410 km discontinuity beneath eastern Tibet,which could be caused by the dynamics of the sub-vertical downward asthenospheric f

关键词： east Tibetan escape flow Sichuan Basin receiver function imaging mantle transition zone

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Acta Mechanica Solida Sinica 1996年第1期9卷 59-65页

作者： Niu, YQ Du, ds Ma, XG Huang, WH HARBIN INST TECHNOL DEPT ASTRONAUT & MECHHARBIN 150001PEOPLES R CHINA HARBIN INST TECHNOL DEPT ASTRONAUT & MECHHARBIN 150001PEOPLES R CHINA

In this paper, the inverse problem of the medium parameters in an inhomogeneous medium is studied and a generalized ray approximate form of the total wave field is described. First, the acoustic wave equation derived from the elastic wave equation is studied, the referential variables and perturbational variables are introduced, and the integral equation of the medium perturbational parameters is obtained. Then from the point of view of the local principles of the wave function in an inhomogeneous medium, a generalized ray approximate form of the total wave field in an inhomogeneous medium is described, and attention is focused on the Fredholm integral equation of the first kind. Finally, the medium parameters in half-plane are inversed. Numerical examples show when the perturbations of the medium parameters are about 0.5, this method can effectively inverse its variation. Apparently, this method is better than the conventional Born weak scattering approximation.

关键词： integral equation generalized ray approximation medium parameters function integral transform

基于芯片的直接进样质谱法和气相色谱-质谱测定莱茵衣藻中的极性脂类

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化学学报 2013年第4期71卷 663-669页

作者：杨大伟范晓蕾 kind.Tobias Fiehn Oliver 郭荣波中国科学院青岛生物能源与过程研究所生物燃料重点实验室青岛266101 中国科学院研究生院北京100039 美国加州大学戴维斯分校-基因组中心戴维斯95616

目前微藻的脂类分析主要侧重于脂肪酸酯、甘油三酯以及细胞内总脂的分析,忽视了极性脂类的分析.本研究建立了一个基于芯片的全自动电喷雾进样系统联用线性离子阱质谱的技术,用于分析莱茵衣藻中的极性脂类.通过数据库Lipidblast鉴定出了3... 详细信息

目前微藻的脂类分析主要侧重于脂肪酸酯、甘油三酯以及细胞内总脂的分析,忽视了极性脂类的分析.本研究建立了一个基于芯片的全自动电喷雾进样系统联用线性离子阱质谱的技术,用于分析莱茵衣藻中的极性脂类.通过数据库Lipidblast鉴定出了35种不同种类的极性脂类,并首次鉴定出20种甜菜碱脂类.同时利用了GC/TOF-MS来检测莱茵衣藻中的游离脂肪酸,发现亚油酸、亚麻酸和棕榈酸是莱茵衣藻中含量最丰富的三种脂肪酸.建立的脂类分析方法为微藻脂类种类全面综合的分析提供了方法上的参考.

关键词：极性脂类莱茵衣藻直接进样质谱法气相色谱-质谱游离脂肪酸