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Inhibitory activities of microalgal fucoxanthin againstα-amylase,α-glucosidase, and glucose oxidase in 3T3-L1cells linked to type 2 diabetes

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Journal of Oceanology and Limnology 2019年第3期37卷 928-937页

作者： KAWEE-AI Arthitaya kim Aaron taehwan kim Sang Moo Department of Marine Food Science and Technology Gangneung-Wonju National UniversityGangneung 25457Republic of Korea Department of Biotechnology Chiang Mai UniversityChiang Mai 50200Thailand Department of Food Science and Biotechnology Kyung Hee UniversityYongin 17104Republic of Korea

Postprandial hyperglycemia is an early indication of type 2 diabetes and the target of many anti-diabetic and anti-obesity studies.α-Glucosidase and α-amylase are the crucial factors in regulating starch digestion and glucose absorption,making them key targets for many studies to treat postprandial *** studied the inhibitory activities of microalgal fucoxanthin against rat-intestinalα-glucosidase and pancreaticα-amylase along with the antidiabetic eff ect to induce diff erentiation in 3T3-L1 pre-adipocytes using Oil Red-O *** displayed strong hindrance activities towardα-amylase in a concentration-dependent manner,with an IC50 value of 0.68mmol/L,whereas weak inhibitory activity against α-glucosidase,with an IC 50 value of 4.75 mmol/*** also considerably elevated glucose oxidase activity in 3T3-L1 cells by 31.3%at 5μmol/*** adipocyte differentiation,fucoxanthin showed lipid accumulation in 3T3-L1 cells with no cytotoxicity up to 20μmol/***,fucoxanthin had no inhibitory activity on glucose-6-phosphate *** results suggest that fucoxanthin might be useful for the prevention of obesity or diabetes by inhibiting carbohydrate-hydrolyzing enzymes and lipid accumulation and be utilized as an ingredient for a functional food or dietary supplement.

关键词： α-glucosidase amylase diabetes fucoxanthin glucose oxidase microalgae

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Turbulent vortex trains in narrow square arrayed rod bundles of a dual-cooled nuclear reactor

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Science China(Technological Sciences) 2013年第9期56卷 2143-2149页

作者： kim taehwan kim Kyung Min BAE Ji-Yeul SHIN Chang Hwan IN Wang-Kee CHO Hyung Hee School of Mechanical Engineering Yonsei University Korea Atomic Energy Research Institute

The dual-cooled nuclear reactor is currently considered for improving the designs of current/future nuclear reactors. Investigation of the thermal-hydraulic characteristics of the nuclear reactor via experiments is essential for commercializing the dual-cooled nuclear reactor. In this paper, the turbulent flow in square arrayed six-rod bundles in the form of magnified copies of the dual-cooled and current OPR-1000 nuclear reactor is experimentally investigated by means of hot-wire anemometry and smoke-wire generation methods. Vortex trains which do not exist in an ordinary reactor subchannel are presented in the subchannel of the dual-cooled reactor. The vortices are induced by a span-wise velocity gradient. This flow pulsation phenomenon increases the inter-channel mixing of the subchannel. To understand the periodic feature of the pulsation, axial/cross velocities are measured and the periodic characteristic frequencies are obtained by a Fast Fourier Transform (FFT) analysis. The peak frequency that represents the quasi-periodic pulsation of the flow is increased with an increase in the axial velocity while the wavelength of the pulsation remains constant within a tested range of the Reynolds number (9000 51000). The vortex trains are highly synchronized with each other, as confirmed by means of visualization.

关键词：核反应堆旋涡列车棒束快速傅立叶变换脉动现象冷却阵列

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Laboratory Study on the Whitening Ability of A New Type of Toothpaste Against the Tobacco Stains on Teeth

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China Detergent & Cosmetics 2021年第1期6卷 54-59页

作者： Zhang Tao Maeng Yoojae kim taehwan PARK Sunkyu LG Household&Health Care R&D(Shanghai)Co. Ltd.China R&D Center LG Household&Health CareLtd.Korea

A whitening toothpaste containing pyrrolidone groups was *** the stain-removal experiment on the hydroxyapatite discs with tobacco stains,the stain-removal abilities of ammonium acryloyldimethyltaurate/VP copolymer and its toothpaste were *** results showed that the new toothpaste containing pyrrolidone groups had good whitening *** new whitening toothpaste had good safety and it had no damage to the soft and hard tissues.

关键词： toothpaste whitening tobacco stain ammonium acryloyldimethyltaurate

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灾害应对手册和系统

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2019年

主讲人： kim taehwan

本期讲座，kimtaehwan教授将为大家介绍了火灾、地震、洪灾、泥石流、矿难等各种自然灾害和人为灾害的预防、应急和救援措施，系统讲解了如何制定应对灾害的紧急预案，理论与实践并重，具有系统性和科学性，欢迎收看。

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超高层火灾安全

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2019年

主讲人： kim taehwan

目前，高楼火灾已经成为威胁城市公众安全和社会发展的主要灾害之一。高楼火灾具有火势蔓延快、疏散困难和扑救难度大的特点，由于高楼结构复杂、人员密集，一旦失火难以控制和逃离。无数高楼火灾案例表明，现有的高楼火灾救援手段不能...

目前，高楼火灾已经成为威胁城市公众安全和社会发展的主要灾害之一。高楼火灾具有火势蔓延快、疏散困难和扑救难度大的特点，由于高楼结构复杂、人员密集，一旦失火难以控制和逃离。无数高楼火灾案例表明，现有的高楼火灾救援手段不能适应高楼的建设发展。研究高楼火灾的特点，了解消防装备的技术状况，对于指导人们正确选择救援逃生设施，正确应对高楼火灾进行应急逃生，具有现实的意义。

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