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Chinese Medical Journal 2015年第21期128卷 2932-2937页

作者： Joon Ha Park jeong Hwi Cho In Hye kim Ji Hyeon Ahn Jae-Chul Lee Bai Hui Chen Bich-Na Shin Hyun-Jin Tae ki-Yeon Yoo SeongKweon Hong II Jun Kang Moo-Ho Won Jong-Dai kim Department of Neurobiology School of Medicine Kangwon National University Chuncheon 200-701 South Korea Department of Physiology College of Medicine Hallym University Chuncheon 200-702 South Korea Department of Biomedical Science Research Institute of Bioscience and Biotechnology Hallym University Chuncheon 200-702 South Korea Department of Oral Anatomy College of Dentistry and Research Institute of Oral Science Gangneung-Wonju National University Gangneung 210-702 South Korea Department of Surgery School of Medicine Kangwon National University Chuncheon 200-701 South Korea Department of Food Science and Nutrition Hallym University Chuncheon 200-702 South Korea Division of Food Biotechnology School of Biotechnology Kangwon National University Chuncheon 200-701 South Korea

Background： Water dropwort （Oenanthejavanica） as a popular traditional medicine in Asia shows various biological properties including antioxidant activity. In this study, we firstly examined the neuroprotective effect of Oenanthejavanica extract （OJE） in the hippocampal comus ammonis 1 region （CA 1 region） of the gerbil subjected to transient cerebral ischemia. Methods： Gerbils were established by the occlusion of common carotid arteries for 5 min. The neuroprotective effect of OJE was estimated by cresyl violet staining. In addition, 4 antioxidants （copper, zinc superoxide dismutase [SOD], manganese SOD, catalase, and glutathione peroxidase） immunoreactivities were investigated by immunohistochemistry. Results： Pyramidal neurons in the CA1 region showed neuronal death at 5 days postischemia; at this point in time, all antioxidants immunoreactivities disappeared in CA1 pyramidal neurons and showed 100 mg/kg, OJE protected CA 1 pyramidal neurons from ischemic damage in many nonpyramidal cells. Treatment with 200 mg/kg, not In addition, 200 mg/kg OJE treatment increased or maintained antioxidants immunoreactivities. Especially, among the antioxidants, glutathione peroxidase immunoreactivity was effectively increased in the CA 1 pyramidal neurons of the OJE-treated sham-operated and ischemia-operated groups. Conclusion： Our present results indicate that treatment with OJE can protect neurons from transient ischemic damage and that the neuroprotective effect may be closely associated with increased or maintained intracellular antioxidant enzymes by OJE.

关键词： Antioxidant Enzymes Hippocampal Comus Ammonis 1 Region: Neuroprotection, Oenanthe Javanica Extract: TransientCerebral Ischemia

Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases

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Journal of Geriatric Cardiology 2015年第3期12卷 208-217页

作者： Kwang Sun Ryu Hyun Woo Park Soo Ho Park Ho Sun Shon Keun Ho Ryu Dong Gyu Lee Mohamed EA Bashir Ju Hee Lee Sang Min kim Sang Yeub Lee Jang Whan Bae Kyung Kuk Hwang Dong Woon kim Myeong Chan Cho Young Keun Ahn Myung Ho jeong Chong Jin kim Jong Seon Park Young Jo kim Yang Soo Jang Hyo Soo kim ki Bae Seung Database and Bioinformatics Laboratory School of Electrical and Computer Engineering Chungbuk National University Cheongju Chungbuk South Korea Human Genome Center Institute of Medical Science University of Tokyo Minatoku Tokyo Japan Faculty of Computer Science and Information Technology University of Meddcal Sciences and Technology Khartoum Sudan Regional Curdiovcascular Disease Center Chungbuk National University Ho spital Cheonglu Chungbuk South Korea Division of Cardiology Department of Internal Medicine College of Medicine Chungbuk National University Cheongju Chungbuk South Korea Department of Cardiology Chonnam National University Hospital Donggu Gwangju South Korea Department of Internal Medicine Kyunghee University Gangdong Hospital Seoul South Korea Department of Internal Medicine Yeungnam University Hospital Medical Center Daegu South Korea Division of Cardiology Yonsei University Severance Hospital Seoul South Korea Cardiovascular Center and Department of Internal Medicine Seoul National University Hospital Seoul South Korea Department of Cardiovascular Medicine Catholic University St. Mary's Hospital Seoul South Korea

Background The clinical significance of complete revascularization for ST segment elevation myocardial infarction （STEMI） pa- tients during admission is still debatable. Methods A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention （PPCI） were analyzed. We used propensity score matching （PSM） to control differences of baseline characteristics between culprit only intervention （CP） and multivessel percutaneous coronary interventions （MP）, and between double vessel disease （DVD） and triple vessel disease （TVD）. The major adverse cardiac event （MACE） was analyzed for one year after discharge. Results TVD patients showed higher incidence of MACE （14.2% vs. 8.6%, P = 0.01）, any cause of revascularization （10.6% vs. 5.9%, P - 0.01）, and repeated PCI （9.5% vs. 5.7%, P = 0.02）, as compared to DVD patients during one year after discharge. MP reduced MACE effectively （7.3% vs. 13.8%, P = 0.03）, as compared to CP for one year, but all cause of death （1.6% vs. 3.2%, P= 0.38）, Ml （0.4% vs. 0.8%, P = 1.00）, and any cause ofrevascularization （5.3% vs. 9.7%, P = 0.09） were comparable in the two treatment groups. Conclusions STEMI patients with TVD showed higher rate of MACE, as compared to DVD MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.

关键词： Culprit only intervention Multivessel intervention Multivessel coronary disease Myocardial infarction Primary percutaneous coronary intervention

X-ray Spectra Calculations for Inspection of Semiconductors with Different Target/Filter Combinations Using MCNPX

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Journal of Physical Science and Application 2016年第4期6卷 8-12页

作者： jeong-Ho kim Hye-Min Park ki-Hyun Park Chan-Jong Park Seung-Ho Lee Dong-Sung kim Joong-Suk Youn Seing-Won Jeon Koan-Sik Joo Department of Physics University of Myongji Yongin KS009 Korea SEC111 Saneop-ro 155 beon-gil Gwonseon-gu Suwon KS002 Korea

X-rays are commonly used for inspecting semiconductors. However, excessive radiation dose could damage semiconductors. Therefore, unnecessary exposure needs to be reduced. The ray quality, which is influenced by the tube voltage and filter, determines the exposure. We designed an X-ray tube for inspecting semiconductors with different target/filter combinations and calculated X-ray spectra using the MCNPX （Monte Carlo n-particle extended） code. The target material was W, and the filters were made of Mo, W, and Zr. The W/W combination showed the lowest flux. The MCNPX code can reduce the development time and cost of the target/filter combination for inspecting semiconductors.

关键词： Inspection semiconductor damage filter MCNPX.

Analysis of Skin Parameters of Korean Men According to the Parts of the Body for Integumentary Physiotherapy Research

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Health 2018年第4期10卷 467-486页

作者： So-Jung kim Ju-Hyun kim jeong-Uk Lee Mee-Young kim Lim-Kyu Lee Byoung-Sun Park Seung-Min Yang Won-deok Lee Ji-Woong Noh Yong-Sub Shin Doo-Ho kim Il-Hyun kim Junghwan kim Laboratory of Health Science & Nanophysiotherapy Department of Physical Therapy Graduate School Yongin University Yongin South Korea Department of Physical Therapy College of Health Welfare Wonkwang Health Science University Iksan South Korea Department of Physical Therapy College of Health Science Honam University Gwangju South Korea The Team of Safety and Quality Management Yeongwol Combined Cycle Power Plant Division Korea Southern Power Plant Busan South Korea Department of Physical Therapy College of Public Health & Welfare Yongin University Yongin South Korea

Studies have demonstrated that some cutaneous biophysical properties vary with the part of the body. The results to date of skin conditions in human skin of multiple parts of the body have not yet been well established. In this study, we assessed the differences in the skin’s sebum, moisture, pores, wrinkles, pigmentation, and elasticity of each body part in Korean men in their 20s. A total of 34 healthy men were enrolled. A Skin Diagnosis Meter was used to measure the skin’s surface sebum, moisture, pores, wrinkles, pigmentation, and elasticity of each body part. The sebum content was significantly higher on the face than at other sites. Moisture was significantly high on the feet. Pores were significantly high on the face. Wrinkles were significantly high on the face. Pigmentation was high on the face and neck, but not significantly. Elasticity was significantly high on the hands. In the correlation analysis results, sebum and pore were positively correlated, but sebum and moisture and wrinkle and elasticity were negatively correlated. For nearly the first time, this study resulted in systematic reference values for standardized biophysical measuring methods and body parts reflecting the skin physiology of healthy South Korean men. The results show that skin’s surface sebum, moisture, pores, wrinkles, pigmentation, and elasticity vary with the part of the body.

关键词： Sebum Moisture Pores Wrinkles Pigmentation Elasticity Total Body

Characteristic Dermatologic Changes in the Condition of Skin after Ultrasonic Stimulation in Healthy Korean Men

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Journal of Cosmetics, Dermatological Sciences and Applications 2018年第4期8卷 195-206页

作者： So-Jung kim Seung-Min Yang Ju-Hyun kim jeong-Uk Lee Mee-Young kim Lim-Kyu Lee Byoung-Sun Park Won-deok Lee Ji-Woong Noh Yong-Sub Shin Doo-Ho kim Il-Hyun kim Junghwan kim Laboratory of Health Science & Nanophysiotherapy Department of Physical Therapy Graduate School Yongin University Yongin Republic of Korea Department of Physical Therapy College of Health Welfare Wonkwang Health Science University Iksan Republic of Korea Department of Physical Therapy College of Health Science Honam University Gwangsan-gu Republic of Korea The Team of Safety and Quality Management Yeongwol Combined Cycle Power Plant Division Korea Southern Power Plant Yeongwol-gun Republic of Korea Department of Physical Therapy College of Public Health & Welfare Yongin University Yongin Republic of Korea

The aim of our study was to recognize different skin conditions of the face and neck using six biophysical parameters and to show the changes after the application of ultrasonic stimulation (US). We assessed the differences in the sebum, moisture, pores, wrinkles, pigmentation, and elasticity of the skin in the face and neck regions. A total of 30 healthy men in their 20s were enrolled. We used a skin diagnosis meter to assess the state of the skin. The sebum and pores of the face were more significant than in the neck. The amount of moisture in the U-zone was significantly higher than in other areas. Statistical differences were found between the pre-and post-measure-ment values in the sebum, moisture, wrinkles and pigmentation. Wrinkles and pigmentation were positively correlated. Our data showed that the changes in skin condition are associated with external stimulants. The effect of US on skin may differ depending on the part of the body, and some biophysical properties of skin vary depending on the location on the body.

关键词： Ultrasonic Stimulation Korean Men Skin

Analysis of Interferential Current Therapy-Induced Skin Changes in Healthy Korean Men

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Natural Science 2018年第11期10卷 436-447页

作者： So-Jung kim Seung-Min Yang Ju-Hyun kim jeong-Uk Lee Mee-Young kim Lim-Kyu Lee Byoung-Sun Park Won-deok Lee Ji-Woong Noh Yong-Sub Shin Doo-Ho kim Il-Hyun kim Kong-Sook Noh Junghwan kim Laboratory of Health Science & Nanophysiotherapy Department of Physical Therapy Graduate School Yongin Uni-versity Yongin-si Republic of Korea Department of Physical Therapy College of Health Welfare Wonkwang Health Science University Iksan-si Republic of Korea Department of Physical Therapy College of Health Science Honam University Gwangju-si Republic of Korea The Team of Safety and Quality Management Yeongwol Combined Cycle Power Plant Division Korea Southern Pow-er Plant Yeongwol-gun Republic of Korea Department of Physical Therapy College of Public Health & Welfare Yongin University Yongin-si Republic of Korea

We examined the changes in numerous skin conditions before and after the ap-plication of interferential current therapy to various regions of healthy male bodies. In this study, we assessed the differences in the skin’s sebum, moisture levels, pores, wrinkles, pigmentation, and elasticity on the shoulders, lower back, and the knees of Korean males in their 20s. A total of 30 healthy males were in-cluded in the study. We used a skin diagnosis meter as a device for measuring the state of the skin. A statistical difference was found when comparing the pre- and post-measurement values in regards to the moisture levels, wrinkles, and pig-mentation. In the correlation analysis results, the sebum and pigmentation, moisture levels and wrinkles, moisture levels and pigmentation, and moisture levels and elasticity were all positively correlated, respectively. The results of this study partially suggest that a change in skin condition is associated with ex-ternal stimulation. The study also found that the effects of the application of in-terferential current therapy on the various skin conditions may differ depending on the region of the body that the application is conducted as well.

关键词： Interferential Current Therapy Korean Men Skin

Sex-based differences in histology,staging,and prognosis among 2983 gastric cancer surgery patients

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World Journal of Gastroenterology 2022年第9期28卷 933-947页

作者： Yonghoon Choi Nayoung kim ki Wook kim Hyeong Ho Jo Jaehyung Park Hyuk Yoon Cheol Min Shin Young Soo Park Dong Ho Lee Hyeon jeong Oh Hye Seung Lee Young Suk Park Sang-Hoon Ahn Yun-Suhk Suh Do Joong Park Hyung-Ho kim Ji-Won kim Jin Won kim Keun-Wook Lee Won Chang Ji HoonPark Yoon Jin Lee Kyoung Ho Lee Young Hoon kim Department ofInternal Medicine Seoul National University Bundang HospitalSeongnam 13620South Korea Nayoung Department of Internal Medicine Seoul National University College of MedicineSeoul 03080South Korea Department of Pathology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Pathology Seoul National University College of MedicineSeoul 03080South Korea Department of Surgery Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Surgery Seoul National University College of MedicineSeoul 03080South Korea Department of Radiology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Radiology Seoul National University College of MedicineSeoul 03080South Korea

BACKGROUND Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer(GC).AIM To analyze the differences in GC characteristics according to sex in patients who underwent surgical treatment for *** A total of 2983 patients diagnosed with gastric adenocarcinoma who received surgical treatment at the Seoul National University Bundang Hospital between 2003 and 2017 were *** clinicopathological characteristics, histologic type of GC, overall and GC-specific survival rates, and associated risk factors were *** Among the 2983 patients, 2005(67.2%) and 978(32.8%) were males and females, *** average age of the female group(59.36 years) was significantly younger than that of the male group(61.66 years;P < 0.001).Cancer of the gastric body(P < 0.001) and diffuse-type histology(P < 0.001) were more common in females than in *** trend was more prominent in females younger than 60 years of age, with a significantly higher proportion of diffuse-type cancer than in the male *** of sex, diffuse-type GC was more common in younger patients, and the proportion of intestinal-type GC increased with *** overall survival rate was significantly higher in females(P < 0.001).However, this difference disappeared for GC-specific survival(P = 0.168), except for the poor GC-specific survival rate in advanced-stage cancer(stage Ⅲ or above) in females(P = 0.045).The risk factors for GC-related mortality were older age, upper location of GC, and diffuse-or mixed-type *** terms of comorbidities, more males died from diseases other than GC, including other malignancies such as lung cancer, hepatocellular carcinoma, and pancreatic cancer, and respiratory diseases such as interstitial lung disease and chronic obstructive pulmonary disease, while there were relatively more cardiovascular or cerebrovascular deaths in *** Sex-based differences in GC were

关键词： Gastric cancer Histology Prognosis Sex difference Survival

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韩国基于风险的大坝安全管理研究现状

大坝与安全 2015年第6期29卷 75-79页

作者： Dong-Hoon Shin ki-Young kim jeong-Yeol Lim 崔弘毅许传桂 Korea Water Resources Corporation 不详

大坝一旦完建,大坝业主和大坝工程师的首要职责就是通过实施检查和安全评估对大坝进行合理的维护,这也是相关条例、法规和法案的要求。之前,韩国的大坝安全评估都是基于规范和定性的方法,没有考虑自然的不确定性。最近,基于风险的大坝... 详细信息

大坝一旦完建,大坝业主和大坝工程师的首要职责就是通过实施检查和安全评估对大坝进行合理的维护,这也是相关条例、法规和法案的要求。之前,韩国的大坝安全评估都是基于规范和定性的方法,没有考虑自然的不确定性。最近,基于风险的大坝安全管理被认为是大坝安全管理下一代范例中真正可靠的选择。笔者介绍了目前传统的制度体系在大坝安全管理中是如何运作的,以及基于风险的大坝安全管理是如何作为一种新的大坝安全范例来引进的。笔者还会介绍一些大坝安全导则和法规来追述韩国大坝安全管理的变化历史。最后,笔者将简要介绍某大坝在大坝风险评估方面开展的工作,这是新的大坝安全范例。

关键词：韩国大坝安全管理风险

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采用ITO纳米粒子喷墨印刷制备透明电极

中国印刷与包装研究 2010年第6期2卷 77-79页

作者： jeong Jin-A LEE Jinho kiM Hongdoo kiM Han-ki NA Seok-In 王晓芳(编译) Department of Advanced Materials Engineering for Information and Electronics Kyung Hee University 1Seocheon-dongYongin-si Gyeonggi-do 446-701 South Korea Korea Institute of Science and Technology ( kiST) 864 - 9 Dunsan-ri Bongdong-eup Wanju-gun Jeollabuk-do 565 -902 Republic of Korea 不详

本文讨论了喷墨印刷氧化铟锡(ITO)电极在有机太阳能电池(OSCs)中的应用。利用纳米ITO晶体进行喷墨印刷并在450℃时迅速退火,可以直接获得平均透光率为84.14%、方块电阻为202.7Ω/□的ITO电极。由喷墨印刷直接制造的ITO电极制备的有机太... 详细信息

本文讨论了喷墨印刷氧化铟锡(ITO)电极在有机太阳能电池(OSCs)中的应用。利用纳米ITO晶体进行喷墨印刷并在450℃时迅速退火,可以直接获得平均透光率为84.14%、方块电阻为202.7Ω/□的ITO电极。由喷墨印刷直接制造的ITO电极制备的有机太阳能电池具有0.57V的开路电压、8.47mA/cm^2的短路电流、44%的填充因子以及2.13%的能量转换率。这表明从有机太阳能电池印刷成本效益来讲,相对于溅射工艺,由于无须光刻工艺且ITO材料的利用率更高,直接利用喷墨印刷制备ITO电极成为一种可行的选择。

关键词： ITO 喷墨印刷直接图形透明度有机太阳能电池