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Comparative associations of non-alcoholic fatty liver disease and metabolic dysfunction-associated steatotic liver disease with risk of incident chronic kidney disease:a cohort study

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Hepatobiliary Surgery and Nutrition 2024年第5期13卷 801-813,I0003-I0005页

作者： Ji Hye Heo Mi Yeon Lee Seong Hwan kim Ming-Hua Zheng Christopher D.Byrne Giovanni Targher ki-chul sung Department of Internal Medicine Hallym University College of MedicineChuncheonRepublic of Korea Division of Biostatistics Department of R&D ManagementKangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoulRepublic of Korea Division of Cardiology Department of Internal MedicineKorea University Ansan HospitalAnsanRepublic of Korea MAFLD Research Center Department of HepatologyThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhouChina Wenzhou Key Laboratory of Hepatology WenzhouChina Institute of Hepatology Wenzhou Medical UniversityWenzhouChina Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province WenzhouChina Nutrition and Metabolism Faculty of MedicineUniversity of SouthamptonSouthamptonUK Southampton National Institute for Health and Care Research Biomedical Research CentreUniversity Hospital SouthamptonSouthamptonUK Metabolic Diseases Research Unit IRCCS Sacro Cuore-Don Calabria HospitalNegrar di ValpolicelleItaly Division of Cardiology Department of Internal MedicineKangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoulRepublic of Korea

Background:We examined the comparative associations between non-alcoholic fatty liver disease(NAFLD)and metabolic dysfunction-associated steatotic liver disease(MASLD)definitions with risk of developing chronic kidney disease(CKD)and abnormal ***:We conducted a cohort study of 214,145 Korean adults with normal kidney function at baseline who underwent liver *** were further subdivided into no steatotic liver disease(no-SLD),NAFLD-only,MASLD-only,both NAFLD and MASLD,and SLD not categorized as NAFLD or MASLD *** proportional hazards models were used to analyze the risk of incident CKD and ***:Compared with either the no-NAFLD or no-MASLD groups,the NAFLD and MASLD groups were associated with a higher risk of incident CKD(NAFLD:adjusted hazard ratio(HR),1.18[95%CI,1.01-1.38];MASLD:adjusted HR,1.21[95%CI,1.04-1.39]).Among the five subgroups,both NAFLD and MASLD group had the strongest association with risk of incident CKD(adjusted HR,1.21[95%CI,1.04-1.42]).The MASLD-only group had the strongest association with incident abnormal albuminuria,with an adjusted HR comparable to that of the both NAFLD and MASLD group(adjusted HR 1.96[95%CI,1.44-2.67]for the MASLD-only,and adjusted HR 1.98[95%CI,1.58-2.49]for the both NAFLD and MASLD group versus the no-SLD group).The NAFLD-only group was not independently associated with risk of CKD or abnormal ***:These findings suggest that MASLD definition identifies individuals at high risk of developing incident CKD or abnormal albuminuria better than NAFLD definition.

关键词： Metabolic dysregulation non-alcoholic fatty liver disease(NAFLD) metabolic syndrome chronic kidney disease(CKD) albuminuria

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高胰岛素血症和稳态模型评估胰岛素抵抗对发生高血压的预测作用:一个韩国人口样本中的5年随访研究

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中华高血压杂志 2012年第2期20卷 198-198页

作者： ki chul sung Soo Lim Robert S.Rosenson 罗冬梅叶鹏

该研究调查血浆胰岛素浓度和稳态模型评估的胰岛素抵抗指数（homeostasis model assessment of insulinresistance，HOMA—IR）是否在一个健康和相对消瘦的韩国成年人口样本中与高血压的发病率相关。方法：研究者从参与2003和2008年一... 详细信息

该研究调查血浆胰岛素浓度和稳态模型评估的胰岛素抵抗指数（homeostasis model assessment of insulinresistance，HOMA—IR）是否在一个健康和相对消瘦的韩国成年人口样本中与高血压的发病率相关。方法：研究者从参与2003和2008年一般健康状况评估，基础血压正常的个体15638人中选取受试者10894人。

关键词：健康状况评估胰岛素抵抗指数高胰岛素血症高血压随访研究预测作用样本人口

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A Rapid Adaptation Approach for Dynamic Air‑Writing Recognition Using Wearable Wristbands with Self‑Supervised Contrastive Learning

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Nano-Micro Letters 2025年第2期17卷 417-431页

作者： Yunjian Guo Kunpeng Li Wei Yue Nam‑Young kim Yang Li Guozhen Shen Jong‑chul Lee Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897South Korea Radio Frequency Integrated Circuit(RFIC)Bio Centre Kwangwoon UniversitySeoul 01897South Korea Department of Electronic Engineering Kwangwoon UniversitySeoul 01897South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China State Key Laboratory of Integrated Chips and Systems Fudan UniversityShanghai 200433People’s Republic of China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081People’s Republic of China

Wearable wristband systems leverage deep learning to revolutionize hand gesture recognition in daily *** existing approaches that often focus on static gestures and require extensive labeled data,the proposed wearable wristband with selfsupervised contrastive learning excels at dynamic motion tracking and adapts rapidly across multiple *** features a four-channel sensing array composed of an ionic hydrogel with hierarchical microcone structures and ultrathin flexible electrodes,resulting in high-sensitivity capacitance *** wireless transmission from a Wi-Fi module,the proposed algorithm learns latent features from the unlabeled signals of random wrist ***,only few-shot labeled data are sufficient for fine-tuning the model,enabling rapid adaptation to various *** system achieves a high accuracy of 94.9%in different scenarios,including the prediction of eight-direction commands,and air-writing of all numbers and *** proposed method facilitates smooth transitions between multiple tasks without the need for modifying the structure or undergoing extensive task-specific *** utility has been further extended to enhance human–machine interaction over digital platforms,such as game controls,calculators,and three-language login systems,offering users a natural and intuitive way of communication.

关键词： Wearable wristband Self-supervised contrastive learning Dynamic gesture Air-writing Human-machine interaction

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^(18)F-fluoro-2-deoxyglucose uptake on PET CT and glucose transporter 1 expression in colorectal adenocarcinoma

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World Journal of Gastroenterology 2012年第2期18卷 168-174页

作者： sung-chul Lim Department of Pathology and Research Center for Resistant cells Medical SchoolChosun UniversityGwangju 501-140South Korea

AIM:To evaluate the correlation between the level of 18 F-fluoro-2-deoxyglucose (18 F-FDG) uptake and glucose transporter 1 (GLUT1) expression in colorectal adenocarcinoma (CRA).METHODS:Forty four patients with resected CRA and preoperative 18 F-FDG positron emission tomography computed tomography data were investigated in this *** of maximum standardized uptake value (SUVmax) of the lesion was made with GLUT1 expression by immunohistochemistry and various clinicopathologic factors including tumor volume,invasion depth,gross finding,and lymph node ***:SUVmax was 14.45 ± 7.0 in negative GLUT1 expression cases,15.51 ± 5.7 in weak GLUT1 expression cases,and 16.52 ± 6.8 in strong GLUT1 expression cases,and there was no correlation between between GLUT1 expression and *** was significantly correlated with tumor volume (P < 0.001).However,there was no significant differences in SUVmax and GLUT1 expression among other clinicopathologic ***:GLUT1 expression does not correlates significantly with 18 F-FDG uptake in CRA.18 F-FDG uptake was increased with tumor volume,which is statistically significant.

关键词： 18^F-fluoro-2-deoxyglucose Glucose trans-porter 1, Colorectal cancer

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Cavity noise sensitivity analysis of tire contour design factors and application of contour optimization methodology

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Journal of Central South University 2012年第8期19卷 2386-2393页

作者： kiM Seong-rae sung ki-deug LEE Dong-woo HUH Sun-chul NEXEN Tire Corporation 30 Yusan-DongYangsan-SiKyungnam 626-230Korea Division of Automotive and Mechanical Engineering Changwon Moonsung University91Doodae-dongChangwon-si Kyungnam 641-771Korea Department of Energy and Mechanical Engineering Institute of Marine IndustryGyeongsang National University Cheondaeguk-Gil 38TongyeongGyeongnam 650-160Korea

Cavity resonance noise of passenger car tires is generated by interacting excitation between a tire structure and the fill gas (air), and generally lies in a frequency range of 200?250 Hz. As such, this noise is strongly perceived and may be a serious source of driver annoyance. Thus, many studies regarding the cavity noise mechanism and its reduction have already been conducted. In this work, a vibro-acoustic coupled analysis was conducted between a tire structure and air cavity. Using this analysis, we can more accurately simulate the tire noise performance in the region of the cavity resonance frequency. An analysis of the effects of variation of tire contour design factors was conducted, using design-of-experiments methods. Finally, a multi-objective optimization was performed using in-house codes to reduce the cavity noise level while minimizing the loss of other performances, such as diminished ride comfort and handling caused by the variations of contour. As a result of this optimization, an optimized contour shape was derived, which satisfied the multi-objective performances.

关键词： tire cavity noise vibro-acoustic coupled analysis finite element method boundary element method (BEM) sensitivity optimization

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Electrochemical and electronic properties of nitrogen doped fullerene and its derivatives for lithium-ion battery applications

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Journal of Energy Chemistry 2018年第2期27卷 528-534页

作者： Parveen Sood ki chul kim Seung Soon Jang School of Materials Science and Engineering Georgia Institute of Technology Atlanta CA 30332-0245. USA Department of Chemical Engineering Konkuk University Seoul 05029 Republic of Korea Institute for Electronics and Nonotechnology Georgia Institute of Technology Atlanta GA 30332-0245 USA Parker H. Petit Institute for Bioengineering and Bioscience Georgia Institute of Technology Atlanta GA 30332-0245 USA

We have studied the redox potentials and electronic properties of C60 and C59N using density functional theory method. It is found that doping C60 with one nitrogen atom results in a slight increase in redox potential. Next, we have also studied C59N functionalized with various redox-active oxygen containing functional groups and strongly electron withdrawing functional groups. It is found that the intrinsic electronic structure of the molecule is the major determinant of the redox potential. Our DFT calculations show that the electron affinity to redox potential of functionalized C59N is correlated with the LUMO of the systems very well. This is the first systematic study on the redox properties and electronic structures of N-doped C60 systems.

关键词： DFT Redox potential C60 Doping Li-ion battery

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Growth and Magnetic Properties of Sol-Gel Derived Co-Doped ZnO Thin Film

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Journal of Rare Earths 2006年第Z1期24卷 59-63页

作者： Young sung kim ki chul kim Won Pil Tae Dae Ho Yoon Tae Seok Park Su Jeong Suh Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Cambridge-ETRI Joint R&D Centre Electronics and Telecommunications Research Institute Daejeon 305-350 Korea Ulsan Industry Promotion Techno Park Ulsan 683-804 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea

Zn1-xCoxO films were grown on glass by sol-gel spin coating process. A homogeneous and stable Zn1-xCoxO sol was prepared by dissolving zinc acetate dihydrate, cobalt acetate tetrahydrate and aluminium chloride hexahydrate as solutes in solution of isopropanol and monoethanolamine. The films were postheated and vacuum annealed, and investigated for c-axis preferred orientation and electromagnetic properties. Zn1-xCoxO films with different Co concentrations were oriented well along the c-axis, especially the Zn1-xCoxO film with 10% Co(atom fraction) was highly c-axis oriented. The transmittance spectra show that Zn1-xCoxO films occur d-d transition and sp-d exchange interaction between Co2+ ions. The electrical resistivity of the films at 10% Co had the lowest value because the crystallite size became largest and the crystallinity of the c-axis was improved. X-ray photoelectron spectroscopy and alternating gradient magnetometer analyses indicated that no Co metal cluster was formed, and the ferromagnetism at room temperature appeared. The characteristics of the electrical resistivity and room temperature ferromagnetism of sol-gel derived Zn1-xCoxO films suggest a potential application of dilute magnetic semiconductor devices.

关键词： sol-gel Zn1-xCoxO thin film dilute magnetic semiconductor (DMS)

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Understanding microstructure and mechanical properties of(AlTa(0.76))xCoCrFeNi(2.1) eutectic high entropy alloys via thermo-physical parameters

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Journal of Materials Science & Technology 2020年第22期54卷 131-137页

作者： Min Jung kim Gyeol Chan Kang sung Hwan Hong Hae Jin Park Sang chul Muna Gian Song ki Buem kim Department of Nanotechnology and Advanced Materials Engineering Sejong University209 Neungdong-roCwangjin-guSeoul143-747South Korea Division of Advanced Materials Engineering Kongju National UniversityCheonanChungnam330-717South Korea

(AlTa(0.76))xCoCrFeNi(2.1)(x values in molar ratio,x=0.1,0.3,0.5,0.7,1.0,and 1.5) alloys were designed to investigate the microstructure and mechanical properties of the eutectic high entropy alloys(EHEAs)consisting of FCC,B2,and Laves *** on the compositional variatio,clear microstructural variation was observed,as follows:(1) Group 1:FCC dendrite+Laves interdendrite(x=0.1),(2) Group 2:FCC dendrite+fine-eutectic structure consisting of FCC and Laves phases(x=0.3,0.5 and 0.7),(3) Group 3:B2 dendrite+bimodal eutectic structure [FCC/B2+Laves](x=1.0),(4) Group 4:Laves dendrite+eutectic structure consisting of B2 and Laves phases(x=1.5).As the fraction of Laves or B2 phases increases,yield stress increases from 293 to 2336 MPa,while the plastic strain decreases from 50 % to 2%.Thermo-physical parameters,such as mixing entropy(△S(mix)),mixing enthalpy(△H(mix)),valence electron concentration(VEC),and atomic size difference(δr),were calculated to understand the microstructural *** criteria(δr-VEC and δr-△H(mix)) were utilized to elucidate the formation of the eutectic structures in the present EHEAs,revealing the usefulness of the thermo-physical parameters in the development of EHEAs.

关键词： High-entropy alloy Eutectic high-entropy alloy Microstructure Mechanical properties Thermo-physical parameter

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Granular cell tumor of the cecum with extensive hyalinization and calcification:A case report

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World Journal of Gastroenterology 2009年第26期15卷 3315-3318页

作者： Ran Hong sung-chul Lim Department of Pathology Chosun University School of Medicine Gwangju 501-140 South Korea Research Center for Resistant tells Chosun University School of Medicine Gwangju 501-140 South Korea

A granular cell tumor (GCT) is a benign neoplasm of unclear histogenesis that is generally believed to be of nerve sheath *** is not common and most often affects the tongue,skin and soft tissue,although it may occur anywhere in the *** experienced a case of GCT that arose in the cecum of a 55-yearold *** GCT was removed by laparoscopic *** addition to the tumor,endoscopic examination revealed the presence of a 5-mm-polyp in the descending colon and multiple tiny polyps in the sigmoid colon and *** examination demonstrated a cecal tumor 1.5 cm × 1.0 cm × 0.7 cm with a hard consistency;in cut sections,mixed cells with yellowish and whitish portions were *** tumor was located between the mucosa and subserosa,and was composed of plump histiocyte-like tumor cells with abundant granular eosinophilic cytoplasm,which were immunoreactive for S-100 protein,vimentin,neuron-specific enolase,inhibin-α and *** tumor showed extensive hyalinization and focal dystrophic *** profiles did not confirm any particular cell type for the histogenetic origin of the GCT,including a nerve sheath *** hyalinization and calcifi cation showing involution of tumor cells suggest benign clinical behavior of GCT.

关键词： Granular cell tumor Cecum Histogenesis Calcification

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UBVVI Surface Photometry of the Spiral Galaxy NGC 300 in the Sculptor Group

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Chinese Journal of Astronomy and Astrophysics 2004年第4期4卷 299-310页

作者： Sang chul kim Hwankyung sung Hong Soo Park Eon-Chang sung Korea Astronomy Observatory Taejon 305-348Republic of KoreaDepartment of Astronomy and Space ScienceSejong University98 Gunja-dongGwangjin-guSeoul 143-747Republic of KoreaAstronomy ProgramSEESSeoul National UniversitySeoul 151-742Republic of KoreaKorea Astronomy ObservatoryTaejon 305-348Republic of Korea

We present UBVI surface photometry over a 20.5' × 20.5' area of the late-type spiral galaxy NGC 300. We have derived isophotal maps, surface brightness profiles, ellipticity profiles, position angle profiles, and color profiles. By merging our I-band measurements with those of Boker et al. based on Hubble Space Telescope observations, we have obtained combined I-band surface brightness profiles for the region 0.02' < r < 500' and have decomposed the profiles into three components: a nucleus, a bulge, and an exponential disk.

关键词： galaxies: spiral - galaxies: photometry - galaxies: individual(NGC 300) - galaxies: nuclei

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