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Neoadjuvant chemoradiotherapy followed by D2 gastrectomy in locally advanced gastric cancer

World Journal of Gastroenterology 2015年第9期21卷 2711-2718页

作者： Mi Sun kim Joon Seok Lim Woo Jin Hyung Yong Chan Lee Sun Young Rha ki chang keum Woong Sub Koom Department of Radiation Oncology Yonsei University College of MedicineSeoul 120-752South Korea Department of Radiology Yonsei University College of MedicineSeoul 120-752South Korea Department of Surgery Yonsei University College of MedicineSeoul 120-752South Korea Department of Internal Medicine Yonsei University College of MedicineSeoul 120-752South Korea Department of Medical Oncology Yonsei University College of MedicineSeoul 120-752South Korea

AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy(NACRT) for resectability of locally advanced gastric cancer(LAGC).METHODS:Between November 2007 and January 2014,29 patients with LAGC(clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT followed by D2 gastrectomy were included in this *** was evaluated with radiologic and endoscopic exams before and after *** threedimensional conformal radiotherapy,patients received 45 Gy,with a daily dose of 1.8 *** entire tumor extent and the regional metastatic lymph nodes were included in the gross tumor *** presenting with a resectable tumor after NACRT received a total or subtotal gastrectomy with D2 *** pathologic tumor response was evaluated using Japanese Gastric Cancer Association histologic evaluation *** morbidity was evaluated using the National Cancer Institute-Common Terminology Criteria for Adverse Events version *** survival(OS) and progression-free survival(PFS) rates were estimated using a Kaplan-Meier analysis and compared using the log-rank ***:All patients were assessed as unresectable ***-four patients(24/29; 82.8%) showed LAGC on positron emission tomography-computed tomography(CT) and contrast-enhanced CT,whereas four patients(4/29; 13.8%) with vague invasion orabutment to an adjacent organ underwent diagnostic *** patient(1/29; 3.4%),initially assessed as a resectable case,underwent an "open and closure" after the tumor was found to be *** to an adjacent organ(34.5%) was the most common reason for *** clinical response rate one month after NACRT was 44.8%.After NACRT,69%(20/29) of patients had a resectable *** the 20 patients with a resectable tumor,18 patients(62.1%) underwent a D2 *** R0 resection rate was 94.4% and two patients(2/18; 11.1%) showed a complete *** median follow-

关键词： Advanced gastric cancer D2 gastrectomy Neoadjuvant

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Analysis of the Clinical Effect of Laparoscopic Total Mesorectal Excision for the Treatment of Middle and Low Rectal Cancer

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Advances in Modern Oncology Research 2019年第6期5卷 10-14页

作者： ki chang keum Lisa Cooper Hiwa Cancer and Hematology Hospital Iraq-Sulaymaniyah-Qirga QuarterIraq Department of Radiation Oncology Gangnam Severance HospitalYonsei University College of MedicineSeoulKorea

The purpose of this study was to analyze the clinical efficacy of laparoscopic total mesorectal excision for the treatment of middle and low rectal ***,30 patients who received treatment in the hospital from March 2013 to May 2018 were randomly selected as the laparotomy group to receive laparotomy.30 patients who received treatment in the hospital from March 2013 to May 2018 were randomly selected as the laparoscopic group to receive laparoscopic *** postoperative and complications of total rectal mesorectal excision were compared between the two *** results showed that the amount of blood loss during laparoscopy was(169.36±106.96)mL,and that during laparoscopy was(180.65±153.22)mL,which was significantly lower than that of the open group(209.65±186.65)mL and(356.54±170.32)*** blood loss in laparoscopic patients was significantly lower than that in the open group,and the difference was statistically significant(t=2.95,2.87,P<0.05).The duration of anal sparing surgery in the laparoscope group was(232.65±56.35)min,which was longer than that in the laparoscope group(227.65±68.65)*** duration of non-sparing anal surgery in the laparoscopic group was(246.95±52.65)min,which was significantly shorter than that in the open group(299.65±64.32)*** was no statistically significant difference in the duration of operation between the laparoscopic group and the open *** recovery time of intestinal function in the laparoscopic group was(2.11±1.82)days,which was significantly shorter than that in the open group(4.63±1.52)*** postoperative hospital stay in the laparoscopic group was(11.32±10.01)d,which was significantly shorter than that in the open group(26.62±12.43 d).The recovery time of intestinal function and postoperative hospital stay of patients in the laparoscopic group were shorter than those in the open group,with statistically significant differences(T=2.31,2.43,P<0.05).The tumor diameter was(4.03±1.20)cm in the

关键词： Laparoscope Total mesangial rectal resection Middle and low rectal cancer

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Synthesis of crosslinked polystyrene particles by seeded batch polymerization with monomer absorption

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 153-159页

作者： ki-chang LEE Han-Ah WI Department of Polymer Science and Engineering Engineering Research Institute Gyeongsang National University

A highly crosslinked, monodispersed polystyrene（PS） particle was prepared by a seeded batch dispersion polymerization with a monomer absorption method. Prior to polymerization, 1,9 lam monodispersed PS seed particles were treated under an optimum condition of monomer absorption. The effects of divinylbenzebe（DVB） concentration and polymerization temperature were examined for styrene（in PS seed）/styrene（in the second stage） mass ratio of 1：1 in the medium range of EtOH/water mass ratio of 100/0-80/20 and 2.3 μm uniform crosslinked PS particles containing 15%-20% （mass fraction） DVB were prepared at 60-70 ℃. The results show that monomer absorption before the second stage of polymerization is more effective to prepare highly crosslinked monodispersed PS particles.

关键词： crosslinked polystyrene particle seeded batch dispersion polymerization monomer absorption divinylbenzene (DVB)

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Local Meteorological and Synoptic Characteristics of Fogs Formed over Incheon International Airport in the West Coast of Korea

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Advances in Atmospheric Sciences 2010年第4期27卷 761-776页

作者： chang ki kiM Seong Soo YUM Department of Atmospheric Sciences Yonsei University 134 Shinchon-dong Seodaemun-gu Seoul 120-749 Korea

Fogs observed over Incheon international airport （IIA） in the west coast of Korea from January 2002 to August 2006 are classified into categories of coastal fog, cold sea fog, and warm sea fog based on the areal extent of the fogs and the difference between the air temperature （T ） and the SST, i.e., cold sea fog if TSST = T -SST 〉 0~0C and warm sea fog if TSST 〈 0~0C. The numbers of coastal, cold, and warm sea fog cases are 64, 26, and 9. Coastal fogs form most frequently in winter, while cold sea fogs occur mostly in summer and warm sea fogs are observed from January to May but not in November and December. On average the air gets colder by 1.6~0C during the three hours leading up to the coastal fog formation, and an additional cooling of 1.1~0C occurs during the fog. The change in the dew point temperature （T_d） is minimal except during the fog （0.6~0C）. Decreases in T for the cold and warm sea fogs are relatively smaller. The average Td is higher than SST during the cold sea fog periods but this T_d is more than 4~0C higher than that for the corresponding non-fog days, suggesting that cold sea fogs be formed by the cooling of already humid air （i.e., T_d〉SST）. Increases of T_d are significant during the warm sea fog periods （1.4~0C）, implying that effcient moisture supply is essential to warm sea fog formation. Four major synoptic patterns are identified in association with the observed fogs. The most frequent is a north Pacific high that accounts for 38% of cases. Surface or upper inversions are present in 77%, 69%, and 81% of the fog periods for coastal, cold, and warm sea fogs, respectively.

关键词： costal fogs sea fogs west coast of Korea meteorological and synoptic characteristics

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Early Cretaceous Tectonism and Diatoms in Korea

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Acta Geologica Sinica(English Edition) 2008年第6期82卷 1179-1184页

作者： ki-Hong chang Sun-Ok PARK Department of Geology Kyungpook National UniversityDaeguKorea

The Early Cretaceous Sindong Group, a non-marine molasse, unconformably overlies the folded earliest Cretaceous Myogok Formation. The tectonism that folded the Jaseong Synthem including the Myogok and other formations is here called the Nakdong-Jaeryeonggang （N-J） tectonism. The Oknyeobong and Dabokni Formations are discussed to show that they belong to the Jaseong Synthem. The Dabokni Formation yielded fossil diatoms whose age has been referred as the ＂earliest Cretaceous＂ based on the geologically constrained age of the fossil-bearing deposit. The age of the N-J tectonism appears Barremian as it is between the Hauterivian Myogok Formation and the Aptian Sindong Group with the TPN （Trigonioides-Plicatounio-Nippononaia） fauna. The N-J tectonism, an orogeny, quite deformed pre-Aptian strata in Korea, but can hardly find its reported equivalent in NE China. A revised correlation table shows that the Jaseong- Sindong sequence corresponds to the Jehol Group of China. The Sindong-Hayang transition was characterized by basin migration and dextral rotation probably caused by the Tan-Lu fault system in a broad sense.

关键词： Early Cretaceous Late Jurassic Dabokni Formation Jaseoung Synthem Nakdong- Jaeryeonggang tectonism Archaic fresh-water diatoms

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Optimal allocation of random access period for wireless body area network

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Journal of Central South University 2013年第8期20卷 2195-2201页

作者： Jin hyuk kiM chang ki HONG Sang bang CHOI Department of Electronic Engineering Inha University

A wireless body area network (WBAN) allows integration of low power, invasive or noninvasive miniaturized sensors around a human body. WBAN is expected to become a basic infrastructure element for human health monitoring. The Task Group 6 of IEEE 802.15 is formed to address specific needs of body area network. It defines a medium access control layer that supports various physical layers. In this work, we analyze the efficiency of simple slotted ALOHA scheme, and then propose a novel allocation scheme that controls the random access period and packet transmission probability to optimize channel efficiency. NS-2 simulations have been carried out to evaluate its performance. The simulation results demonstrate significant performance improvement in latency and throughput using the proposed MAC algorithm.

关键词： wireless body area network channel efficiency quality of service low latency

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Unilateral foveomacular retinitis resembling solar retinopathy among young soldiers in Korean army and associated multimodal imaging findings

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International Journal of Ophthalmology(English edition) 2020年第1期13卷 112-119页

作者： chang ki Yoon Kyu Hyung Park Se Joon Woo Department of Ophthalmology Seoul National University College of MedicineSeoul National University Bundang HospitalSeongnam 13620Korea Department of Ophthalmology Hallym University College of MedicineHallym University Kangnam Sacred Heart HospitalSeoul 07441Korea

AIM: To describe the clinical features and multimodal images of unilateral foveomacular retinitis in young Korean soldiers. METHODS: Ten patients having foveomacular retinitis were included. Fluorescein angiography, fundus autofluorescence(FAF), infrared reflectance(IR), and spectral-domain optical coherence tomography(SD-OCT) were ***: All patients were young males experienced insidious visual decline without exposure to bright light. Initial and final vision ranged from hand movement to 20/20(median 20/200) and 20/2000 to 20/20(median 20/500), respectively. Vision decreased in 6 patients while improved in two. Typical macular abnormality was yellow granular spots. SD-OCT showed ellipsoid zone(EZ) or interdigitation zone(IZ) disruption of fovea. The degree of EZ/IZ damage correlated with vision. Lesions were clearly visualized through IR and matched with SD-OCT ***: This is the first case series of foveomacular retinitis diagnosed with multimodal imaging. Foveomacular retinitis should be suspected in sudden unilateral visual decline especially in young soldiers. SD-OCT is the most important diagnostic modality.

关键词： foveomacular retinitis Korean multimodal imaging solar retinopathy soldiers unilateral

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Memristive Devices Based on Two-Dimensional Transition Metal Chalcogenides for Neuromorphic Computing

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Nano-Micro Letters 2022年第4期14卷 29-58页

作者： ki chang Kwon Ji Hyun Baek Kootak Hong Soo Young kim Ho Won Jang Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoul 08826Republic of Korea Interdisciplinary Materials Measurement Institute Korea Research Institute of Standards and Science(KRISS)Daejeon 34133Republic of Korea Department of Materials Science and Engineering Institute of Green Manufacturing TechnologyKorea UniversitySeoul 02841Republic of Korea Advanced Institute of Convergence Technology Seoul National UniversitySuwon 16229Korea

Two-dimensional(2D)transition metal chalcogenides(TMC)and their heterostructures are appealing as building blocks in a wide range of electronic and optoelectronic devices,particularly futuristic memristive and synaptic devices for brain-inspired neuromorphic computing *** distinct properties such as high durability,electrical and optical tunability,clean surface,flexibility,and LEGO-staking capability enable simple fabrication with high integration density,energy-efficient operation,and high *** review provides a thorough examination of high-performance memristors based on 2D TMCs for neuromorphic computing applications,including the promise of 2D TMC materials and heterostructures,as well as the state-of-the-art demonstration of memristive *** challenges and future prospects for the development of these emerging materials and devices are also *** purpose of this review is to provide an outlook on the fabrication and characterization of neuromorphic memristors based on 2D TMCs.

关键词： Two-dimensional materials Memristors Neuromorphic computing Artificial synapses Transition metal chalcogenides

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Effect of citrulline on post-exercise rating of perceived exertion,muscle soreness,and blood lactate levels:A systematic review and meta-analysis

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Journal of Sport and Health Science 2020年第6期9卷 553-561页

作者： Hye chang Rhim Sung Jong kim Jewel Park ki-Mo Jang College of Medicine Korea UniversitySeoul 02842Republic of Korea Department of Orthopaedic Surgery Anam HospitalKorea University College of MedicineSeoul 02841Republic of Korea

Background:Citrulline is one of the non-essential amino acids that is thought to improve exercise performance and reduce post-exercise muscle *** conducted a systematic review and meta-analysis to determine the effect of citrulline supplements on the post-exercise rating of perceived exertion(RPE),muscle soreness,and blood lactate ***:A random effects model was used to calculate the effect sizes due to the high variability in the study design and study populations of the articles included.A systematic search of PubMed,Web of Science,and *** was *** for study inclusion was limited to studies that were randomized controlled trials involving healthy individuals and that investigated the acute effect of citrulline supplements on RPE,muscle soreness,and blood lactate *** supplementation time frame was limited to 2 h before *** types and number of participants,types of exercise tests performed,supplementation protocols for L-citrulline or citrulline malate,and primary(RPE and muscle soreness)and secondary(blood lactate level)study outcomes were extracted from the identified ***:The analysis included 13 eligible articles including a total of 206 *** most frequent dosage used in the studies was 8 g of citrulline *** supplementation significantly reduced RPE(n=7,p=0.03)and muscle soreness 24-h and 48-h after post-exercise(n=7,p=0.04;n=6,p=0.25,respectively).However,citrulline supplementation did not significantly reduce muscle soreness 72-h post-exercise(n=4,p=0.62)or lower blood lactate levels(n=8,p=0.17).Conclusion:Citrulline supplements significantly reduced post-exercise RPE and muscle soreness without affecting blood lactate levels.

关键词： Amino acids Dietary supplements Ergogenic aid Nitric oxide Watermelon juice

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Xenos peckii vision inspires an ultrathin digital camera

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Light(Science & Applications) 2018年第1期7卷 272-278页

作者： Dongmin keum Kyung-Won Jang Daniel S.Jeon Charles S.H.Hwang Elke K.Buschbeck Min H.kim ki-Hun Jeong Department of Bio and Brain Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Korea School of Computing Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Korea Department of Biological Sciences University of CincinnatiCincinnatiOH 45221-0006USA

Increased demand for compact devices leads to rapid development of miniaturized digital ***,conventional camera modules contain multiple lenses along the optical axis to compensate for optical aberrations that introduce technical challenges in reducing the total thickness of the camera ***,we report an ultrathin digital camera inspired by the vision principle of Xenos peckii,an endoparasite of paper *** male Xenos peckii has an unusual visual system that exhibits distinct benefits for high resolution and high sensitivity,unlike the compound eyes found in most insects and some *** biologically inspired camera features a sandwiched configuration of concave microprisms,microlenses,and pinhole arrays on a flat image *** camera shows a field-of-view(FOV)of 68 degrees with a diameter of 3.4mm and a total track length of *** biologically inspired camera offers a new opportunity for developing ultrathin cameras in medical,industrial,and military fields.

关键词： camera sandwich digital

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