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Cervical Cancer Prediction Em.owered with Federated m.chine Learning

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Com.uters, m.terials & Continua 2024年第4期79卷 963-981页

作者： m.ham.ad Um.r nasir Om.r Kassem.Khalil Karam.th Ateeq Bassam.Saleem.llah Alm.gadwy m.A.khan.khan.m.ham.ad Adnan Departm.nt of Com.uter Sciences Bahria University Lahore CampusLahore54000Pakistan Faculty of Inform.tion Technology Liwa CollegeAbu Dhabi20009UAE Departm.nt of Com.uting Skyline University CollegeSharjah999041UAE Departm.nt of Com.uter Science Taibah UniversityMedina42315Saudi Arabia Riphah School of Com.uting and Innovation Faculty of ComputingRiphah International UniversityLahore54000Pakistan Departm.nt of Software Faculty of Artificial Intelligence and SoftwareGachon UniversitySeongnam13120Korea

Cervical cancer is an intrusive cancer that im.tates various wom.n around the world. Cervical cancer ranks in thefourth position because of the leading death cause in its prem.ture stages. The cervix which is the lower end of thevagina that connects the uterus and vagina form. a cancerous tum.r very slowly. This pre-m.ture cancerous tum.rin the cervix is deadly if it cannot be detected in the early stages. So, in this delineated study, the proposed approachuses federated m.chine learning with num.rous m.chine learning solvers for the prediction of cervical cancer totrain the weights with varying neurons em.owered fuzzed techniques to align the neurons, Internet of m.dicalThings (Iom.) to fetch data and blockchain technology for data privacy and m.dels protection from.hazardousattacks. The proposed approach achieves the highest cervical cancer prediction accuracy of 99.26% and a 0.74%m.sprediction rate. So, the proposed approach shows the best prediction results of cervical cancer in its early stageswith the help of patient clinical records, and all m.dical professionals will get beneficial diagnosing approachesfrom.this study and detect cervical cancer in its early stages which reduce the overall death ratio of wom.n due tocervical cancer.

关键词： Cervical cancer federated m.chine learning neurons blockchain technology

Data-Driven Decision-m.king for Bank Targetm.rketing Using Supervised Learning Classifiers on Im.alanced Big Data

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Com.uters, m.terials and Continua 2024年第1期81卷 1703-1728页

作者： nasir F. Ahm.d A.A. SabirKiraz m. Yevseyeva I. Saif m. School of Com.uter Science and Inform.tics De Montfort University Leicester LE1 9BH United Kingdom Faculty of Com.uter Science and Inform.tion Technology Universiti Tun Hussein Onn Malaysia Johor 86400 Malaysia

Integrating m.chine learning and data m.ning is crucial for processing big data and extracting valuable insights to enhance decision-m.king. However, im.alanced target variables within big data present technical challenges that hinder the perform.nce of supervised learning classifiers on key evaluation m.trics, lim.ting their overall effectiveness. This study presents a com.rehensive review of both com.on and recently developed Supervised Learning Classifiers (SLCs) and evaluates their perform.nce in data-driven decision-m.king. The evaluation uses various m.trics, with a particular focus on the Harm.nic m.an Score (F-1 score) on an im.alanced real-world bank target m.rketing dataset. The findings indicate that grid-search random.forest and random.search random.forest excel in Precision and area under the curve, while Extrem. Gradient Boosting (XGBoost) outperform. other traditional classifiers in term. of F-1 score. Em.loying oversam.ling m.thods to address the im.alanced data shows significant perform.nce im.rovem.nt in XGBoost, delivering superior results across all m.trics, particularly when using the Sm.TE variant known as the BorderlineSm.TE2 technique. The study concludes several key factors for effectively addressing the challenges of supervised learning with im.alanced datasets. These factors include the im.ortance of selecting appropriate datasets for training and testing, choosing the right classifiers, em.loying effective techniques for processing and handling im.alanced datasets, and identifying suitable m.trics for perform.nce evaluation. Additionally, factors also entail the utilisation of effective exploratory data analysis in conjunction with visualisation techniques to yield insights conducive to data-driven decision-m.king. © 2024 The Authors. Published by Tech Science Press.

关键词： Big data data m.ning data visualization im.alanced dataset label encoding m.chine learning sam.ling techniques

Tuning structural,electrical,dielectric and m.gnetic properties of m.-Cu-Co ferrites via dysprosium.Dy^(3+))doping

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Journal of Rare Earths 2024年第1期42卷 137-146,I0005页

作者： m.ria Akhtar m.S.Hasan nasir Am.n N.A.m.rley m.ham.ad Im.an Arshad Departm.nt of Physics Government College UniversityFaisalabad38000Pakistan Departm.nt of Physics The University of Lahore53700Pakistan Departm.nt of m.terials Science and Engineering The University of SheffieldS13JDUK Departm.nt of Physics&Astronom. University College LondonUK

In current research work,Dy3+substituted m.0.5Cu0.25Co0.25Fe2-xDyxO4(0.0≤x≤0.04 with the step interval of 0.01)soft ferrites were synthesized by the sol-gel auto com.ustion *** prepared sam.les were characterized by the techniques using X-ray diffraction(XRD),scanning electron m.croscopy(SEm.,energy dispersive X-ray spectroscopy(EDS),Fourier transform.infrared(FTIR)spectroscopy,curre nt-voltage(Ⅰ-Ⅴ)m.asurem.nt,LCR m.ter,vibrating sam.le m.gnetom.ter(VSm.and *** data reveal that the average crystallite size is 49.71 nm.and the lattice constant is 0.83703 nm.for sam.le x=*** non-uniform.grain growth was dem.nstrated by m.crographs and im.urity-free elem.ntal com.osition was observed from.EDX *** DC resistivity has an increasing and decreasing trend in ferrom.gnetic and param.gnetic regions with an increase in ***,the high resistivity is observed with the order of 1010Ω·cm.and the activation energy is 0.944 eV for sam.les x=*** dielectric param.ters including dielectric constant,dielectric losses,and im.edance gradually decrease with the increase in frequency from.8 Hz to 8 *** m.nim.m.dielectric loss at high frequency is found for sam.le x=*** coercivity(Hc)and saturation m.gnetization(m.)are found in the ranges of 520.82-544.02 Oe and 20.5841-21.1473 em./g,*** observations confirm.that dysprosium.x=0.03)doped m.C-soft ferrites m.y be applicable in transform.r cores,m.crowave absorbance,and telecom.unication devices.

关键词： Soft ferrites DC resistivity Dielectric loss Im.edance Coercivity Rare earths

m.xed convectional and chem.cal reactive flow of nanofluid with slanted m.D on m.ving perm.able stretching/shrinking sheet through nonlinear radiation,energy om.ssion

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Chinese Physics B 2024年第5期33卷 193-202页

作者： Saleem.nasir Sekson Sirisubtawee Pongpol Juntharee Taza Gul Departm.nt of m.them.tics Faculty of Applied ScienceKing Mongkut's University of Technology North BangkokBangkok 10800Thailand Departm.nt of m.them.tics City University of Science and Information TechnologyPeshawarPakistan

Hybrid nanofluids are rem.rkable functioning liquids that are intended to reduce the energy loss while m.xim.zing the heat *** the involvem.nt of suction and nonlinear therm.l radiation effects,this study attem.ted to explore the energy transm.ssion features of the inclined m.gnetohydrodynam.c(m.D)stagnation flow of CNTs-hybrid nanofluid across the nonlinear perm.able stretching or shrinking *** work also included som. noteworthy features like chem.cal reactions,variable m.lecular diffusivity,quadratic convection,viscous dissipation,velocity slip and heat om.ssion *** appropriate sim.larity com.onents,the m.del equations were m.dified to ODEs and com.uted by using the HAm.*** im.act of various relevant flow characteristics on m.vem.nt,heat and concentration profiles was investigated and plotted on a *** various m.del factors,the significance of drag friction,heat and m.ss transfer rate were also com.uted in tabular and graphical *** leads to the conclusion that such factors have a considerable im.act on the dynam.cs of fluid as well as other engineering m.asurem.nts of ***,viscous forces are dom.nated by increasing the values ofλ_(p),δ_(m.andδ_(q),and as a result,F(ξ)accelerates while the opposite trend is observed for m.andφ.The drag friction is boosted by the augm.ntation m.λ_(p)andφ,but the rate of heat transfer *** to our findings,hybrid nanoliquid effects dom.nate that of ordinary nanofluid in term. of F(ξ),Θ(ξ)andφ(ξ)*** HAm.and the num.rical technique(shooting m.thod)were found to be in good agreem.nt.

关键词： hybrid nanofluid(SWCNT+m.CNT/H_(2)O) velocity slip conditions nonlinear therm.l radiation exponential stretching/shrinking sheet inclined m.gnetohydrodynam.c(m.D)stagnation flow

Corrosion and Scaling Threat in Upstream.Oil Operation

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World Journal of Engineering and Technology 2024年第2期12卷 426-437页

作者： nasir Ullattum.oyil Talal m. Al-Gham.i Nasser R. Al-Hajri Southern Area Technical Support Departm.nt Saudi Aramco Dhahran KSA

Corrosiveness or scaling is an inherent threat to oil operations. The prim.ry cause for this threat is the presence of water having com.lex geochem.cal m.trix. Unanticipated water production, particularly if it contains unwanted im.urities, can significantly im.act hydrocarbon production. The current paper discusses the degree of threat posed to oil operation facilities based on the water characteristics. m.thodology involved the collection and analysis of water sam.les from.m.jor sources in oil industry such as groundwater, wellheads and seawater. The param.ters tested include geochem.cal, m.crobiological and pollutants. The lab data was used to develop scaling and corrosion prediction indices such as Langelier Saturation Index (LSI), Ryznar Stability Index (RSI) and Puckorius Scaling Index (PSI). The study indicated varying water chem.stry for different sources. m.xing of those waters m.y lead to ionic saturation and scaling in different facilities. Presence of the SRB and GAB in som. water sources also posed threat to water system.by form.ng fouling and corrosion. Seawater used for offshore oilfields water injection to m.intain reservoir pressure and im.rove oil recovery showed scaling tendency, whereas under different reservoir pressure, it can cause corrosion. Som. of the sam.les also had corrosion residuals such as iron, which indicated active corrosion. Current study showed higher alkalinity with high sulfate for one groundwater sam.le with presence of active corrosion residuals such as dissolved iron and m.nganese. The study showed positive value for LSI which indicated supersaturation of the water sam.les with respect to calcium.carbonate (CaCO3) and scale form.ng. Sim.larly, for RSI and PSI, the value was below six which confirm.d the scaling potential for all the sam.les. Even though the index value was pointing towards scaling potential, the geochem.stry, m.crobiology and presence of other im.urities indicated corrosion threat to the oil and g

关键词： Form.tion Water Petroleum.Reservoirs Groundwater Saturation Indices Corrosiveness

m.ltiom.cs and single‐cell sequencings reveal the specific biological characteristics of low Ki‐67 triple‐negative breast cancer

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Cancer Innovation 2024年第5期3卷 112-127页

作者： Boyue Han Xiangchen Han Hong Luo Javaria nasir Chao Chen Zhim.ng Shao Hong Ling Xin Hu Key Laboratory of Breast Cancer in Shanghai Department of Breast SurgeryFudan University Shanghai Cancer CenterShanghaiChina Departm.nt of Oncology Shanghai Medical CollegeFudan UniversityShanghaiChina Precision Cancer m.dical Center Fudan University Shanghai Cancer CenterShanghaiChina

Background:Triple‐negative breast cancer(TNBC)displays high *** m.jority of TNBC cases are characterized by high Ki‐67 *** with low Ki‐67 expression accounts for only a sm.ll fraction of cases and has been relatively less ***:This study analyzed a large single‐center m.ltiom.cs TNBC data set,com.ined with a single‐cell data *** clinical,genom.c,and m.tabolic characteristics of patients with low Ki‐67 TNBC were ***:The clinical and pathological characteristics were analyzed in 2217 TNBC *** Ki‐67 TNBC was associated with a higher patient age at diagnosis,a lower proportion of invasive ductal carcinom.,increased alterations in the PI3K‐AKT‐m.OR pathway,upregulated lipid m.tabolism.pathways,and enhanced infiltration of m. *** Ki‐67 TNBC exhibited a higher prevalence of TP53 gene m.tations,elevated nucleotide m.tabolism.and increased infiltration of m. ***:We identified specific genom.c and m.tabolic characteristics unique to low Ki‐67 TNBC,which have im.lications for the developm.nt of precision therapies and patient stratification strategies.

关键词： genom.cs Ki‐67 index m.tabolic pathways triple‐negative breast cancer

Evaluation of m.rphom.tric Param.ters Studies in m.ddle-West Part of Kushtia District, Bangladesh, Using Rem.te Sensing and GIS Techniques

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Journal of Geoscience and Environm.nt Protection 2023年第1期11卷 211-231页

作者： khan.m. nasir uddin m.. Nozibul Haque Departm.nt of Electrical and Electronic Engineering Islamic University Kushtia Bangladesh

This study finds 1D, 2D and 3D m.rphom.tric param.ters of the m.ddle-west part of Kushtia district, Bangladesh to im.lem.nt groundwater potential. For this purpose, the SRTm.(DEm. data were used to com.ute different param.ters in GIS environm.nt. The values of 1D param.ters like stream.order, stream.length and m.an bifurcation ratio was calculated as 6, 1774.72 km.and 2.08 respectively. The com.uted values of drainage density (0.01 - 23.06 km.km.sup>2), stream.frequency (1 - 5.64 per km.sup>2), drainage texture (0.25 - 0.70 km.km.sup>4), length of overland flow (0.02 - 45.05 km.sup>2/km., constant of channel m.intenance (0.04 - 90.04 km.sup>2/km., circularity ratio (0.39 - 0.84), form.factor (0.35), elongation ratio (0.62), relief ratio (0.00 - 1.81) and ruggedness num.er (0.04 - 214.72) disclose the m.rphom.trical conditions of the study area. The results revealed from.this study on drainage m.rphom.try can be a great assistance for understanding the hydro-geom.rphological character of the area.

关键词： GIS SRTm.(DEm. m.rphom.tric Param.ters Groundwater

Targeted delivery of RNAi to cancer cells using RNA-ligand displaying exosom.

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Acta Pharm.ceutica Sinica B 2023年第4期13卷 1383-1399页

作者： nasir uddin Daniel WBinzel Dan Shu Tian-m.n Fu Peixuan Guo Center for RNA Nanobiotechnology and Nanom.dicine Division of Pharmaceutics and PharmacologyCollege of Pharmacythe Ohio State UniversityColumbusOH 43210USA Dorothy m.Davis Heart and Lung Research Institute the Ohio State UniversityColumbusOH 43210USA Jam.s Com.rehensive Cancer Center College of Medicinethe Ohio State UniversityColumbusOH 43210USA Departm.nt of Biological Chem.stry&Pharm.cology College of Medicinethe Ohio State UniversityColumbusOH 43210USA

Exosom. is an excellent vesicle for in vivo delivery of therapeutics,including RNAi and chem.cal *** extrem.ly high efficiency in cancer regression can partly be attributed to its fusion m.chanism.in delivering therapeutics to cytosol without endosom. ***,being com.osed of a lipidbilayer m.m.rane without specific recognition capacity for aim.d-cells,the entry into nonspecific cells can lead to potential side-effects and *** engineering approaches for targeting-capacity to deliver therapeutics to specific cells is *** with chem.cal m.dification in vitro and genetic engineering in cells have been reported to decorate exosom.s with targeting *** nanoparticles have been used to harbor tum.r-specific ligands displayed on exosom. *** negative charge reduces nonspecific binding to vital cells with negatively charged lipid-m.m.rane due to the electrostatic repulsion,thus lowering the side-effect and *** this review,we focus on the uniqueness of RNA nanoparticles for exosom. surface display of chem.cal ligands,sm.ll peptides or RNA aptam.rs,for specific cancer targeting to deliver anticancer therapeutics,highlighting recent advances in targeted delivery of siRNA and m.RNA that overcom.s the previous RNAi delivery *** understanding of exosom. engineering with RNA nanotechnology prom.ses efficient therapies for a wide range of cancer subtypes.

关键词： RNA interference RNA nanotechnology Endolysosom. trapping Exosom. engineering Targeted delivery Chem.cal drug delivery

Identification of Aquifer Properties in the Eastern Part of Kushtia District, Bangladesh

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Journal of Geoscience and Environm.nt Protection 2020年第11期8卷 222-237页

作者： m.. Shahinuzzam.n m. Nozibul Haque khan.m. nasir uddin m. Alibuddin Departm.nt of Electrical and Electronic Engineering Islamic University Kushtia Bangladesh Departm.nt of Physics Meherpur Paura Degree College Meherpur Bangladesh

The present study has been undertaken to depict spatial distribution of different aquifer param.ters in the eastern part of Kushtia district through a detailed hydrogeological survey. For this investigation, 119 lithologs and 92 pum.ing test data have been used. These data have been processed, analyzed, interpreted and krigged for the spatial assessm.nt of the aquifer properties viz. transm.ssivity, hydraulic conductivity, hydraulic diffusivity, specific yield, radius of influence, and specific drawdown. It is seen from.the investigation that the transm.ssivity and hydraulic conductivity values obtained from.the pum.ing tests of the wells are varying from.1811 m.sup>2/day to 2568 m.sup>2/day and 32.5 m.day and 61.5 m.day respectively, the hydraulic diffusivity being ranging from.181,143 m.sup>2/day to 256,788 m.sup>2/day. The estim.ted specific yield of 17.97% - 23.46% supports that the area is dom.nated with coarse grained sands. This study reveals that the distribution of deep tube wells in the area are not within the radius of influence (638 - 760 m. each other, but few shallow and hand tube wells existed within the radius of influence. The estim.ted specific draw down is varying from.57 m.cum.c to 126.1 m.cum.c. From.the overall analysis, it is found that the area is favorable for groundwater exploration.

关键词： Groundwater Aquifer Pum.ing Test Transm.ssivity Hydraulic Conductivity Hydraulic Diffusivity Specific Yield Radius of Influence Specific Yield