检索结果-南通市图书馆

Regulation of embryo implantation by nitric oxide in mouse

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2002年第17期47卷 1461-1465页

作者： Zhang, X Wang, hm Lin, HY Li, QL Liu, DL Qian, D Liu, GY Zhu, C Chinese Acad Sci State Key Lab Reprod Biol Inst Zool Beijing 100080 Peoples R China

Intrauterine injection and zymography were used to investigate the effect of nitric oxide (NO) on embryo implantation in mice. On day 3, one uterine horn of female pregnant mice was injected intraluminally with various doses of nitric oxide synthase (NOS) inhibitor, N-nitro-L-arginine methyl ester (L-NAME), while the contralateral horn served as control. Animals were sacrificed by cervical dislocation on day 7 of gestation, and the number of implanted embryos in each horn was calculated. The results showed that lower doses (0.05mg L-NAME) did not inhibit implantation significantly (P > 0.05), but high doses (0.2 mg L- NAME) resulted in a significant reduction in the number of implanted embryos (P < 0.05). Co-administration of SNP, a generator of NO, with L-NAME would reverse the anti-implantation effect of L-NAME. To further understand the precise mechanism of NO in implantation, matrix metallo-proteinase (MMPs) activities were detected by gelatin zymography. The reduction in the number of implanted

关键词： mouse nitric oxide nitric oxide synthase embryo im-plantation matrix metalloproteinases.

Assessment of oxidative stress in chronic pancreatitis patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第35期12卷 5705-5710页

作者： Mariette Verlaan Hennie MJ Roelofs Annie van Schaik Geert JA Wanten Jan BMJ Jansen Wilbert hm Peters Joost PH Drenth Department of Gastroenterology Radboud University Nijmegen Medical Centre The Netherlands

AIM: To assess the levels of antioxidant capacity and oxidative damage in blood of chronic pancreatitis (CP) patients in comparison with those in healthy control sub- jects, by using several different analytical techniques. METHODS: Thirty-five CP patients and 35 healthy con- trol subjects were investigated prospectively with re- spect to plasma levels of thiols, ferric reducing ability of plasma (FRAP, i.e. antioxidant capacity), levels of protein carbonyls and thiobarbituric acid reactive substances (TBARS). Additionally, we evaluated the production of reactive oxygen species (ROS) in whole blood. RESULTS: The antioxidative thiols including cysteine, cysteinylglycine and glutathione were significantly lower in CP patients. In addition, the non-enzymatic antioxi- dant capacity was significantly lower in CP patients, which correlated with the amount of oxidative protein (protein carbonyls) and the extent of lipid damage (TBARS), both were significantly higher in CP patients. The ROS production in whole blood after stimulation with phorbol 12-myritate 13-acetaat, demonstrated a strong tendency to produce more ROS in CP patients. CONCLUSION: Oxidative stress may contribute to the pathogenesis of chronic pancreatitis by decreasing anti- oxidant capacity and increasing oxidative damage in CP patients may be a rationale for intervention with antioxi- dant therapy.

关键词： Chronic pancreatitis Oxidative stress Thiols Ferric reducing ability of plasma Protein carbonyls Thiobarbituric acid reactive substances Reactive oxygen species

Experimental study of gold distribution in the algae-organic matter-fluid system

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Science Bulletin 1997年第19期42卷 1640-1642页

作者： Xie, SC Yin, HF Wang, hm Zhou, XG Fu, JM Sheng, GY Zhang, HZ Lu, JL School of Geosciences China University of Geosciences Wuhan China Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou China

THE previous simulating experiments show that many algae can greatly accumulate goldfrom solution under some conditions. Some other experiments further indicate that organ-ic matter and crude oil can also play an important role in gold geochemistry processes such asleaching, migration, reduction and precipitation. However, these biometallogeneses are

关键词： gold algae organic matter fluid metallogenesis.

在线全文

学校读者我要写书评

暂无评论

IL－2对NOD鼠糖尿病的影响

中华微生物学和免疫学杂志 1994年第3期14卷 168-172页

作者：张志利 Geor.,hm 山西医学院第一附属医院

ＮＯＤ鼠是人类胰岛素依赖型糖尿病的动物模型，其发病与自身免疫有关。环磷酰胺（ＣＰ）可以加速这一过程，使ＮＯＤ鼠糖尿病的发病率提高或提前。一些研究表明：ＮＯＤ鼠的淋巴细胞在淋巴细胞混合反应中（ＭＬＲ），在有或无刺激物的... 详细信息

ＮＯＤ鼠是人类胰岛素依赖型糖尿病的动物模型，其发病与自身免疫有关。环磷酰胺（ＣＰ）可以加速这一过程，使ＮＯＤ鼠糖尿病的发病率提高或提前。一些研究表明：ＮＯＤ鼠的淋巴细胞在淋巴细胞混合反应中（ＭＬＲ），在有或无刺激物的存在下，白细胞介素２（ＩＬ－２）的产量均明显低于正常鼠的淋巴细胞。该实验对注射了一次大剂量的ＣＰ（３００ｍｇ／ｋｇ体重）后的ＮＯＤ鼠试用了ＩＬ－２治疗。结果显示：对于年幼的ＮＯＤ鼠ＩＬ－２治疗１４无可以明显减轻注射ＣＰ后的胰岛破坏加速。病理检查显示三组胰岛炎严重程度积分分别为２９；８１；８８。ＩＬ－２处理组明显低于ＣｏｎＡ处理组与对照组。这个研究还显示，对于１２周龄的ＮＯＤ鼠，经１４天的ＩＬ－２治疗，可以完全预防ＣＰ诱导的糖尿病的发生。糖尿病发病率在ＩＬ－２组为０／１２；对照组为７／１２。但对已发病的ＮＯＤ鼠自发性糖尿病ＩＬ－２不能使其缓解。

关键词：白细胞介素2 NOD 糖尿病

Etiological study for a case of multi-bacterial synergistic gangrene

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 1997年第6期42卷 511-517页

作者： Xu, JG Yang, hm Lai, XH Fu, XL Wu, JM Huang, LB Yu, XJ Wu, YP Wu, YJ Liu, BY Priority Laboratory of Molecular Medical Bacteriology Ministry of Health Institute of Epidemiology and Microbiology Chinese Academy for Preventive Medicine Beijing China Laboratory of Bacteriology Beijing Army General Hospital Beijing China

IN July of 1994, a 13-year old girl from Shandong Province, China, found a dark point on her middle finger of the right hand. She licked it with a needle, and washed clothes with pool water by hands afterwards. Intolerable pain was experienced about 10h later. The gangrene was developed in a week and spread gradually up to the right forearm and two fingers of the left hand. In November of 1994, she visited Beijing Army General Hospital, and radical amputations of the right forearm and two fingers of the left hand were carried out after 3d of

关键词： gangrene anaerobes antibiotics.

吸附柱出口温度随时间的变化规律及其数值模拟

在线全文

学校读者我要写书评

暂无评论

离子交换与吸附 2005年第1期21卷 17-26页

作者：李立清,唐新村,Hans-Jürgen Rhm 湖南大学环境科学与工程系中南大学化学化工学院 Department of Mechanical Engineering University Bochum Bochum44780 Germany 长沙410082 长沙4100823

在不同温度 (15℃、20℃、25℃) 下,测试了活性炭 C40/4 吸附有机气体丙酮的吸附热引起吸附柱出口温度的变化。理论分析了吸附过程的能量守恒模型,在其他物质守恒,动量守恒和吸附平衡数学模型的基础上,采取有限差分方法,并借助计算软件 ... 详细信息

在不同温度 (15℃、20℃、25℃) 下,测试了活性炭 C40/4 吸附有机气体丙酮的吸附热引起吸附柱出口温度的变化。理论分析了吸附过程的能量守恒模型,在其他物质守恒,动量守恒和吸附平衡数学模型的基础上,采取有限差分方法,并借助计算软件 ATHENA VIUALWORKBENCH 对模型进行了数值解。探讨了物质轴向扩散系数,吸附热对吸附柱出口温度随时间变化规律的影响,发现吸附质轴向扩散系数是一个很小的数,可忽略不计,从而简化了模型。数值计算结果与实验结果能很好地相吻合。为获得吸附过程中有效传热系数提供了有效的解决方法,并为吸附过程的设计、预测和优化提供支持。

关键词：活性炭丙酮吸附数值模拟吸附热

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

钢琴城堡唯美旋律精选集华丽版 5

MECHANISMS INVOLVED IN THE REDUCTION OF INFARCT SIZE BY ACE INHIBITIOR AFTER LEFT CORONARY ARTERY LIGATION IN RATS

2019年

作者： hm的钢琴城堡

本书是一本唯美旋律精选钢琴曲集。全书精选各大剧集的主题曲、插曲，并为有一定程度的琴友作还原编配，提供挑战难度。每首歌曲旁都有演奏视频可扫描二维码观看，建议先观看视频找到音乐感觉，再练习，更易上手。

ISBN: (纸本)9787540488963

关键词：钢琴曲世界选集

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

Chinese Medical Journal 1995年第3期 80-81页

作者： Zhu YC Stauss hm Redlich Th Adamiak D Mott A Unger Th Department of Pharmacology University of Heidelberg Heidelberg GermanyDepartment of Pharmacology University of Heidelberg Heidelberg GermanyDepartment of Pharmacology University of Heidelberg Heidelberg GermanyDepartment of Pharmacology University of Heidelberg Heidelberg GermanyDepartment of Pharmacology University of Heidelberg Heidelberg GermanyDepartment of Pharmacology University of Heidelberg Heidelberg Germany

The contribution of the inhibition of angiotensin Ⅱ (ANGⅡ) synthesis and bradykinin (BK) breakdown to the effects of ACE inhibition on infarct size, cardiac hypertrophy and blood supply to the marginal zone of the i... 详细信息

关键词： ACE BK MECHANISMS INVOLVED IN THE REDUCTION OF INFARCT SIZE BY ACE INHIBITIOR AFTER LEFT CORONARY ARTERY LIGATION IN RATS ATI LCA

在线全文

学校读者我要写书评

暂无评论

情报科学的发展

国外情报科学 1993年第4期11卷 4-6,22页

作者： Kibi.,hm 冉旭

无论怎么看,情报科学都在蓬勃发展着。工业倔国家矗。多年来经过深恿热虑,重新褥整了他们的情报基础结搀,以适应情报领域的新发展。人们对情报本身进行了深入研究并对情报与臣民经济的相互关系作了探讨e当然,作为情报处理的一种工具,计... 详细信息

无论怎么看,情报科学都在蓬勃发展着。工业倔国家矗。多年来经过深恿热虑,重新褥整了他们的情报基础结搀,以适应情报领域的新发展。人们对情报本身进行了深入研究并对情报与臣民经济的相互关系作了探讨e当然,作为情报处理的一种工具,计算机在这方面是非常重要的·另外,人机对话研究为研究情报现象提供了一块肥沃的土壤。[第一段]

关键词：情报学发展中国家