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Outpatient insulin use in type 2 diabetes mellitus and acute respiratory distress syndrome outcomes:A retrospective cohort study

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World Journal of Clinical Cases 2024年第17期12卷 2966-2975页

作者： Georges Khattar Samer Asmar Laurence Aoun Fares Saliba Shaza Almardini Saif Abu Baker Catherine Hong Carolla El Chamieh Fadi Haddadin Toni Habib Omar Mourad Zeina Morcos Fatema Arafa Jonathan Mina khalil El Gharib Mohammad Aldalahmeh Salman Khan Elie Bou Sanayeh Department of Medicine Holy Spirit University of KaslikJounieh 00000Lebanon Department of Internal Medicine Staten Island University HospitalStaten IslandNY 10305United States Public Heath and Biostatistics Independent ResearchBeirut 0000Lebanon Department of Medicine Lebanese UniversityBeirut 00000Lebanon Department of Medicine University of BalamandBeirut 00000Lebanon Department of Medicine Lebanese American UniversityBeirut 00000Lebanon Department of Medicine Northwell Health Staten Island University HospitalNew YorkNY 10305United States

BACKGROUND The impact of type 2 diabetes mellitus(T2DM)on acute respiratory distress syndrome(ARDS)is debatable.T2DM was suspected to reduce the risk and complications of ***,during coronavirus disease 2019(COVID-19),T2DM predisposed patients to ARDS,especially those who were on insulin at *** evaluate the impact of outpatient insulin use in T2DM patients on non-COVID-19 ARDS *** We conducted a retrospective cohort analysis using the Nationwide Inpatient Sample *** patients diagnosed with ARDS were stratified into insulin-dependent diabetes mellitus(DM)(IDDM)and non-insulindependent DM(NIDDM)*** applying exclusion criteria and matching over 20 variables,we compared cohorts for mortality,duration of mechanical ventilation,incidence of acute kidney injury(AKI),length of stay(LOS),hospitalization costs,and other clinical *** Following 1:1 propensity score matching,the analysis included 274 patients in each ***,no statistically significant differences emerged between the IDDM and NIDDM groups in terms of mortality rates(32.8%vs 31.0%,P=0.520),median hospital LOS(10 d,P=0.537),requirement for mechanical ventilation,incidence rates of sepsis,pneumonia or AKI,median total hospitalization costs,or patient disposition upon *** Compared to alternative anti-diabetic medications,outpatient insulin treatment does not appear to exert an independent influence on in-hospital morbidity or mortality in diabetic patients with non-COVID-19 ARDS.

关键词： Acute respiratory distress syndrome Type 2 diabetes mellitus Insulin Length of stay Mortality Endotracheal intubation Acute kidney injury Coronavirus disease 2019

Telecommunications reforms in Pakistan-lessons and suggestions for China

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China Communications 2007年第2期4卷 106-114页

作者： Muhammad khalil Shahid Tang Shou-lian School of Economics and Management Beijing University of Posts and TelecommunicationsBeijingChina

The worldwide strategy for the development of telecommunications has been the opening of the telecom sector to competition and private *** paper focuses on telecommunications reforms and its outcomes in Pakistan and discusses some lessons and suggestions for China who is still in the process of formulating telecom *** liberalization and deregulation,telecom industry in Pakistan is tremendously growing and is in a transition phase from the monopoly to the *** policies and independent regulator is playing critical role in this *** paper suggests that speed up formulation of Telecom Law,establishment of independent regulatory and antitrust agencies are need of time for the China telecom ***,China will have to give special attention to accommodate convergence in its coming model of telecommunications reforms.

关键词： Pakistan China reforms telecommunications regulations competition

Ameliorated effects of Lactobacillus delbrueckii subsp. lactis DSM 20076 and Pediococcus acidilactici NNRL B-5627 on Fumonisin B1-induced Hepatotoxicity and Nephrotoxicity in rats

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Asian Journal of Pharmaceutical Sciences 2016年第2期11卷 326-336页

作者： Amira A. Abdellatef Ashraf A. khalil Department of Protein Technology Institute of Genetic Engineering and Biotechnology City of Scientific Research and Technological ApplicationsBorg El-Arab

Oxidative stress has been implicated in a number of human regeneration and disease processes including atherosclerosis, pulmonary fibrosis, cancer, and different neurodegenerative *** aim of this study was to evaluate the protective effects of Lactobacillus delbrueckii subsp. lactis DSM 20076 (LL-DSM) and Pediococcus acidilactici NNRL B-5627 (PA-NNRL) against the hepatic-and nephro-toxicity of fumonisin B1 (FB1) in FB1-treated rats for an experimental period of 4-weeks. Eighty mature male Sprague-Dawley rats were divided to 12 groups: 1 untreated group;3 groups fed by a FB1-contaminated diet (50, 100 and 200 mg FB1/kg diet,respectively);1 group fed orally by LL-DSM(1 ml/d);1 group fed orally by PA-NNRL (1 ml/d);3 groups co-administered by FB1-contaminated diet and LL-DSM (1 ml/d), and 3 groups coadministered by FB1-contaminated diet and PA-NNRL(1 ml/d). Malonaldehyde (MDA) nitric oxide, glutathione content, SOD activity, total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) were determined. DPA assay was used to assess apoptosis in liver and kidney *** animals fed with FB1-contaminated diet showed a significant increase in oxidative stress markers and DNA fragmentation accompanied with significant decrease in GSH content, SOD activity, and TAC in liver and kidney tissues, especially at highdosage of FB1 (T200). Probiotics antioxidant strains (LL-DSM and PA-NNRL) relatively succeeded to restore almost all parameters investigated as well as to reduce DNA fragmentation in liver and kidney tissues. As a conclusion, probiotics may induce its protective role via increasing the antioxidant capacity, inhibition of lipid peroxidation, scavenging of free radicals and decreasing DNA lesions in liver and kidney of experimental animals tested.

关键词： Fumonisin B1 Lactic acid bacteria Oxidative stress Antioxidant activity Lipid peroxidation Apoptosis

Neural network control for earthquake structural vibration reduction using MRD

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Frontiers of Structural and Civil Engineering 2019年第5期13卷 1171-1182页

作者： Khaled ZIZOUNI Ley la FALI Younes SADEK Ismail khalil BOUSSERHANE ArcihPEL Laboratory University TAHRI MohammedBecharPB 417Algeria FIMAS Laboratory University TAHRJ MohammedBecharPB 417Algeria Laboratory of Smart-Grid and Renewable Energies University TAHRI MohammedBecharPB 417Algeria

Structural safety of building particularly that are intended for exposure to strong earthquake loads are designed and equipped with high technologies of control to ensure as possible as its protection against this brutal load. One of these technologies used in the protection of structures is the semi-active control using a Magneto Rheological Damper device. But this device need an adequate controller with a robust algorithm of current or tension adjustment to operate which is further discussed in the following of this paper. In this study, a neural network controller is proposed to control the MR damper to eliminate vibrations of 3-story scaled structure exposed to Tohoku 2011 and Boumerdes 2003 earthquakes. The proposed controller is derived from a linear quadratic controller designed to control an MR damper installed in the first floor of the structure. Equipped with a feedback law the proposed control is coupled to a clipped optimal algorithm to adapt the current tension required to the MR damper adjustment. To evaluate the performance control of the proposed design controller, two numerical simulations of the controlled structure and uncontrolled structure are illustrated and compared.

关键词： MR damper semi-active control earthquake vibration neural network linear quadratic control

The present state of complementary medicine regulation in Saudi Arabia

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Journal of Integrative Medicine 2019年第3期17卷 147-149页

作者： Tamer Aboushanab Mohamed khalil Yaser Al Ahmari National Center for Complementary and Alternative Medicine Ministry of Health

The prevalence of use of traditional and complementary medicine in the Saudi Arabia population has reached 75%. The most used therapies are religious healing, herbal medicine and cupping therapy. The National Center for Complementary and Alternative Medicine is the Saudi national reference for all activities regarding complementary medicine. This article briefly highlights the current state of complementary medicine regulation in Saudi Arabia.

关键词： Complementary medicine Integrative medicine Cupping Acupuncture Saudi Arabia

Carrier Density and Electric Field Dependent Nonlinear Transport of Chemical Vapor Deposition Graphene

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Chinese Physics Letters 2013年第3期30卷 127-130页

作者： khalil Hafiz M.W. KELEKCI Ozgur NOH Hwayong Department of Physics and Graphene Research Institute Sejong UniversitySeoul 143-747Korea

We report on the measurements of nonlinear current-voltage characteristics of graphene fabricated by chemical vapor *** current-voltage characteristic is described by a power law with a superlinear dependence of the current on the voltage,and the nonlinearity depends on the carrier density and the excitation *** nonlinearity is strongest at the Dirac point and becomes weaker as the carrier density *** the Dirac point,we also observe a crossover to a much stronger nonlinear transport when the electric field increases above 104 V/m.

关键词： deposition. nonlinearity nonlinear

Strain Geometry and Vorticity Analysis of the Deformed Radiolarian Rocks in the Abade-Tashk Area,the Zagros Suture Zone,Iran

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Journal of Earth Science 2022年第2期33卷 525-540页

作者： Roghyeh Tavakkoli khalil Sarkarinejad Saeede Keshavarz Seyed Rahim Hosseini Department of Earth Sciences School of ScienceShiraz UniversityShiraz ***Iran Department of Earth Sciences Graduate University of Advanced TechnologyKerman ***Iran

Deformation in the Zagros suture zone is a result of the oblique collision of the AfroArabian continent with the Central Iranian *** types of folding and faulting are characteristic features of the study area and indicate the performance of a high strain tectonic regime in this *** distinguish deformation geometry during the collisional events,strain measurements have been carried out,using the R_(f)/φ method on deformed radiolarian microfossils,in the Zagros suture *** on the results,the strain ellipsoid shape is in the range of general flattening to plane strain(K=0.16 – 1.12).Measured mean kinematic vorticity number(W_(m)) in the deformed radiolarian rocks ranges between 0.50 and 0.87,which implies that exhumation of the Abade-Tashk area was facilitated by a general shear flow(35%

关键词： transpression Zagros suture zone deformed radiolarian microfossils vorticity analysis Abade-Tashk area tectonicstranspression Zagros suture zone deformed radiolarian microfossils vorticity analysis Abade-Tashk area tectonics

Efficient Ru -catalyzed synthesis of 9-aryl-9H-xanthene-3,6-diols as precursors to fluorones

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Chinese Chemical Letters 2012年第2期23卷 165-168页

作者： khalil Tabatabaeian Alireza Khorshidi Ali Dadashi Milad Khoshnood Department of Chemistry Faculty of SciencesUniversity of GuilanP.O.Box 41335-1914Iran

Efficient condensation of resorcinol and various aromatic aldehydes in the presence of RuCl_3nH_2O as a homogeneous catalyst under reflux conditions was *** was found that a very simple method afforded good to excelle... 详细信息

关键词： Aldehyde Resorcinol Ruthenium Xanthenediol Fluorone

Aortic valve stenosis： treatments options in elderly high-risk patients

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Journal of Geriatric Cardiology 2016年第6期13卷 473-474页

作者： khalil Fattouch Sebastiano Castrovinci Patrizia Carita Cardiovascular Department Maria Eleonora Hospital Palermo Italy

In the last decades, a trend towards a worldwide aging has been reported and diseases which are common in the elderly people would have important implications in clinical practice. Aortic stenosis （AS） is perhaps the most common and most often cause of sudden death among valvular heart diseases. Its prevalence is low among adults aged 〈 60 years, but increases to almost 10% in adults ≥ 80 years.[2] Since the degenerative calcific disease represents the lead- ing cause of AS in developed countries, the improved understanding on its pathogenesis （atherosclerotic processes and/or skeleton key） may offer potentially new targets for preventing and inhibiting AS development and progres- sion.[3] Patients with AS are generally asymptomatic for a prolonged period and the development of symptoms is a critical point in the natural history. Indeed, the prognosis changes dramatically with the onset of symptoms of angina,

关键词： Aortic valve stenosis Elderly patients Minimaly invasive surgery Risck stratification Transcatheter aortic valve implantation