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作者： khalil ahmed saleh al-mekhlafi（哈里力）东北师范大学

学位级别：硕士

With the development of Internet technology, methods, and tools of the development of information systems, especially in electronic commerce field, leads to make theoretical and practical studies for developing electronic commerce systems. Since Yemen is a developing country, we have to pay a great deal of attention to the great role that the Internet plays in the world of business. This thesis presents study of the state of development information systems in Yemen especially in E-Commerce information systems, also focusing on the methods and tools which were used in the developing information systems in Yemen, and the rate of using Object-Oriented Software Engineering in the universities and software companies of Yemen through developing information systems. The study showed that about 95% of information systems in Yemen were developed by using traditional software engineering, only about 5% of information systems were developed by using Object-Oriented software engineering. Since Yemeni government is moving towards E-Commerce & E-Government and Based on the above results, this thesis also presents case study of developing electronic commerce information system of Online Bookstore System (OBS) for sales the books through the Internet.On one hand , the Online Bookstore System has been developed by using the Object-Oriented technology as software engineering methodology based on Coad & Yourdon method for Object-Oriented Analysis model which has five layers and Object-Oriented Design model which has four components, because the Coad & Yourdon method is easy to study and apply. The case study can be seen as 3-Tier Architecture E-Commerce System which has become popular today. On the other hand, every developer, programmer, and who interested in developing information systems especially in electronic commerce systems and software engineering can make use of such kind of this thesis.

关键词： Object-Oriented Analysis Object-Oriented Design E-Commerce C/S Structure B/S Structure

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Blockchain for secure and decentralized artificial intelligence in cybersecurity: A comprehensive review

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Blockchain(Research and Applications) 2024年第3期5卷 184-208页

作者： ahmed M.Shamsan saleh Department of Information Technology University of TabukTabuk47512Saudi Arabia

As the use of artificial intelligence (AI) grows within the field of cybersecurity, so does the demand for secure and decentralized AI systems to protect against potential cyber threats. Blockchain technology has emerged as the ideal approach for increasing both the security and privacy of AI systems since it provides decentralized and immutable data storage. This systematic literature review focuses on the integration of blockchain technology with decentralized AI within cybersecurity. It provides a comprehensive taxonomy of blockchain technology and decentralized AI for cybersecurity, serving as the starting point for the study. This paper begins with an overview of blockchain technology and its possible uses in cybersecurity and also analyzes its challenges and opportunities. Decentralized AI is also covered in the study, along with its potential advantages and difficulties in decentralized AI cybersecurity. Building on that foundation, this study provides convincing findings highlighting the beneficial relationships between blockchain technology and decentralized AI for cybersecurity, contributing to a nuanced comprehension of their integration. Moreover, it offers real-world uses of blockchain-enabled, decentralized AI to discuss its usefulness in tackling cybersecurity concerns. Finally, this paper discusses future research directions for blockchain-enabled decentralized AI in cybersecurity, including potential applications and implications of this technology in the field, emphasizing the potential of blockchain-enabled decentralized AI in cybersecurity to enhance security, privacy, and trust in AI systems.

关键词： Blockchain Artificial intelligence Decentralized Cybersecurity

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The necessity to expand mycorrhizal boundaries:Including the fungal endophytes that possess key mycorrhizal criteria

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Pedosphere 2024年第2期34卷 520-523页

作者： khalil KARIMAN Zed RENGEL Rodica PENA saleh RAHIMLOU Mark TIBBETT UWA School of Agriculture and Environment The University of Western AustraliaPerth WA 6009Australia Department of Sustainable Land Management&Soil Research Centre School of AgriculturePolicy and DevelopmentUniversity of ReadingReading RG66ARUK Department of Ecology and Evolutionary Biology University of MichiganAnn Arbor MI 48109USA

Dear editor,This letter aims to urge the necessity to expand the boundaries of mycorrhizal symbiosis to include certain root fungal *** conventional classification of mycorrhizal associations emphasizes specialized fu... 详细信息

关键词： editor specialized interface

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The interplay mechanism between IDH mutation, MGMT-promoter methylation, and PRMT5 activity in the progression of grade 4 astrocytoma: unraveling the complex triad theory

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Oncology Research 2024年第6期32卷 1037-1045页

作者： MAHER KURDI alAA alKHOTANI ABDULRAHMAN SABBAGH EYAD FAIZO ahmed I.LARY ahmed K.BAMAGA MAJID alMANSOURI BADR HAFIZ THAMER alSHARIF saleh BAEESA Department of Pathology Faculty of MedicineKing Abdulaziz UniversityRabighSaudi Arabia Department of Pathology College of MedicineUmm Al-Qura UniversityMakkahSaudi Arabia Department of Surgery Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Surgery Faculty of MedicineUniversity of TabukTabukSaudi Arabia Section of Neurosurgery Department of SurgeryKing Abdulaziz Medical CityJeddahSaudi Arabia Department of Pediatrics Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Clinical Biochemistry Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Neurosciences King Faisal Specialist Hospital and Research CenterJeddahSaudi Arabia Department of Surgery King Abdulaziz Specialist HospitalTaifSaudi Arabia

Background:The dysregulation of Isocitrate dehydrogenase(IDH)and the subsequent production of 2-Hydroxyglutrate(2HG)may alter the expression of epigenetic proteins in Grade 4 *** interplay mechanism between IDH,O-6-methylguanine-DNA methyltransferase(MGMT)-promoter methylation,and protein methyltransferase proteins-5(PRMT5)activity,with tumor progression has never been ***:A retrospective cohort of 34 patients with G4 astrocytoma is classified into IDH-mutant and IDH-wildtype *** groups were tested for MGMT-promoter methylation and PRMT5 through methylation-specific and gene expression PCR ***-cohort statistical significance was ***:Both IDH-mutant WHO grade 4 astrocytomas(n=22,64.7%)and IDH-wildtype glioblastomas(n=12,35.3%)had upregulated PRMT5 gene expression except in one *** of the 22 IDH-mutant tumors,10(45.5%)tumors showed MGMT-promoter methylation and 12(54.5%)tumors had unmethylated *** IDH-wildtype tumors had unmethylated *** was a statistically significant relationship between MGMT-promoter methylation and IDH in G4 astrocytoma(p-value=0.006).Statistically significant differences in progression-free survival(PFS)were also observed among all G4 astrocytomas that expressed PRMT5 and received either temozolomide(TMZ)or TMZ plus other chemotherapies,regardless of their IDH or MGMT-methylation status(p-value=0.0014).Specifically,IDH-mutant tumors that had upregulated PRMT5 activity and MGMT-promoter methylation,who received only TMZ,have exhibited longer ***:The relationship between PRMT5,MGMT-promoter,and IDH is not ***,accumulation of D2-hydroxyglutarate(2-HG),which partially activates 2-OG-dependent deoxygenase,may not affect their *** IDH-wildtype glioblastomas,the 2HG-2OG pathway is typically inactive,leading to PRMT5 *** alone,compared to TMZ-plus,can increase PFS in upregulated PRMT5 ***,using a PRMT5 inhibitor in G4

关键词： Grade 4 astrocytoma Glioblastoma Isocitrate dehydrogenase(IDH) O-6-methylguanine-DNA methyltransferase(MGMT) Protein methyltransferase proteins-5(PRMT5) Progression-free survival(PFS)

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Kaoline-based catalyst for a high stability desulfurization of sour heavy naphtha in a three-phase oscillatory baffled reactor

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Particuology 2024年第1期84卷 249-260页

作者： Hassan M.Hmood Saba A.Gheni Safaa M.R.ahmed Mudheher M.ali Hamid Yonis saleh Mohammed H.Mohammed Awad E.Mohammed Marwan A.Mahomood Hiba R.Mohammed ahmed A.Hassan Adam Harvey North Refineries Company Ministry of OilIraq Chemical Engineering Department Tikrit UniversityIraq Ministry of Oil Iraq al-Hawija Technical Institute Northern Technical UniversityMoselIraq School of Engineering Newcastle UniversityUK

To meet the rapidly increasing demand for energy and the dramatic depletion of conventional crude oil,it is imperative to utilize sour *** no coke being produced,oxidative desulfurization(ODS)of naphtha lowers its sulfur content and average molecular *** this article,we outline a method for heavy naphtha non-extractive ODS using a very stable *** technique involves the use of a solid catalyst with oxygen gas as the *** necessitated relatively high mixing intensities;hence a three-phase Oscillatory Baffled Reactor(OBR)was *** catalyst was based on the zeolite ZSM-5,prepared from natural kaolin by a series of delamination and activation steps and impregnated with Fe.A TiO2 nanolayer was applied,using the sol-gel method,to prevent rapid *** reactor performance was evaluated to minimize the sulfur content in the naphtha *** to the protective coating,the sulfur conversion stabilized at 90%.The results of this work establish the use of natural clay-based catalysts in a continuous,three-phase ODS,particularly with regard to proving long-term *** also showed that modest ODS can be achieved using an environmentally friendly oxidant,at mild operating conditions,whilst maintaining stability.

关键词： Natural kaoline Desulfurization Three-phase Oscillatory baffled reactor

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Delayed Grafting as a Valid Technique in Burn Management: Experience from a Burn Unit in Oman

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Modern Plastic Surgery 2024年第1期14卷 9-14页

作者： Taif alsafy Joe Jacob Anish Thadathil Elias ahmed Salah El Din Salim Mohammed Ghawas Majid Tariq Saud albusaidi ahmed al Jabri al Anood al Hadhrami Mutazz Obeid al Khaldi Moath Abdelhamid Shummo Karim Mohamed Haridi Aml Eid saleh Said al-Busaidi Department of Plastic and Reconstructive Surgery Sultan Qaboos Hospital Salalah Oman ENT Department Al Nahdha Hospital Muscat Oman Department of Plastic Reconstructive and Craniofacial Surgery Khoula Hospital Muscat Oman

Background: Early excision and grafting has been the preferred method of managing major burns around the world since 1970. Considering the advances in health care and the development of new antibiotics over the past 50 years, delayed grafting as a technique for the management of burns over 15%-20% of total body surface area (TBSA) could have comparable results to that of early excision. This study aims to highlight the outcomes of practicing delayed grafting in burn patients. Methods: A case series analysis was performed of 51 patients who were admitted to the burns unit in Sultan Qaboos Hospital Salalah with over 20% TBSA between January 2014 and December 2019. The patients received prophylactic antibiotics and silver sulphadiazine dressing until the burn eschar had completely separated, followed by grafting. Results: Two patients were lost during the entire duration of the study. The mortality rate was comparable to that of early excision, while the rate of hypertrophic scarring was lower than the range reported by other studies. Conclusion: In the management of patients with over 20% TBSA, delayed grafting after complete separation of eschar is still a valid technique.

关键词： Burns Burn Units Burn Management Delayed Grafting Major Burns Treatment Efficacy

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加速康复外科对初次全膝关节置换术后血液管理的影响：倾向评分匹配分析

加速康复外科对初次全膝关节置换术后血液管理的影响：倾向评分匹...

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作者： Mogalli Abdullah saleh Hussein ahmed 吉林大学

学位级别：硕士

背景:全膝关节置换术(TKA)是缓解慢性膝关节炎患者关节疼痛和增强关节功能的重要手段。TKA的并发症常常与大量失血相关,并直接导致术后血红蛋白水平下降,从而高达69%的患者需要异体输血来应对术后贫血。这已被证明是增加不良结果风险的... 详细信息

背景:全膝关节置换术(TKA)是缓解慢性膝关节炎患者关节疼痛和增强关节功能的重要手段。TKA的并发症常常与大量失血相关,并直接导致术后血红蛋白水平下降,从而高达69%的患者需要异体输血来应对术后贫血。这已被证明是增加不良结果风险的独立因素,包括延长住院时间和增加术后感染的易感性。由丹麦学者Henrik Kehlet于1997年首次提出的加速康复外科(ERAS)已成为现代外科实践中的一个关键方法。ERAS最初在腹部手术中实施,逐渐扩展到包括骨科和泌尿科在内的各个医学专业。然而,尽管ERAS方案的采用日益增加,系统评估关节置换术后的血液指标仍然有限。这种多方面的策略在减轻手术压力、加速术后恢复、减少住院时间和提高整体功能结果方面发挥着重要作用,同时保持低并发症率。之前的研究已证明ERAS在减少失血和优化全髋关节置换术结果方面的有效性。问题是这些发现是否也适用于TKA。THA和TKA之间的关键区别,包括患者人口统计学、手术时间和软组织损伤程度,强调了优化每项手术中患者护理的需要。TKA患者通常比THA患者平均年龄更大,皮肤对皮肤时间更长,并且由于股骨和胫骨截骨术,软组织损伤增加。ERAS方案有效控制围手术期失血量。ERAS组术后CRP和ESR水平较低,表明炎症和凝血活动减少,这可能归因于ERAS计划提供的全面护理,其中包括人性化和以患者为中心的干预措施,以减轻焦虑。ERAS手术已显示出相当大的好处,例如通过利用术前优化、术中程序和术后管理等循证策略,最大限度地减少围手术期失血、降低并发症和改善营养状况。WOMAC、OKS和SF-12的理想结果表明ERAS方案有利于改善术后短期内的短期恢复和生活质量结果。目的:评估在加速康复外科(ERAS)下进行单侧全膝关节置换术(TKA)的患者的血液指标管理效果。材料与方法:回顾性研究了2019年1月至2023年10月在我们医院接受单侧TKA的患者。通过使用0.2校准器进行倾向评分匹配后,这些病例被分为两组:非ERAS组(n=51)接受标准护理,ERAS组(n=51)接受全面ERAS管理。术后比较了主要血液参数/血液指标,同时在第3个月随访时也评估了临床结果。结果:ERAS组术后Hb明显高于非ERAS组(Palb明显少于非ERAS组(P<0.05)。WOMAC和OKS得分在第1个月和第3个月均在ERAS组。结论:ERAS方案在术后第一天到第三个月的术后期间提供了良好且现实的临床和功能结果,对接受单侧初次TKA的患者满意度很高。此外,ERAS方案已被证明可以有效减少围手术期失血、最大限度地减少术后并发症并维持这些患者的最佳营养水平。

关键词：全膝关节置换术快速康复血液管理住院时间并发症随访

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Takotsubo Cardiomyopathy Triggered by Acute Pancreatitis: A Case Report

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Case Reports in Clinical Medicine 2024年第4期13卷 87-94页

作者： Ketevan Kapanadze Elene Shengelia Keti Solomnishvili ahmed saleh Abdelkader Maha Kassem Internal Medicine and Intensive Therapy Department Tbilisi Central Hospital Tbilisi Georgia Internal Medicine Residency Program Tbilisi State Medical University Tbilisi Georgia School of Medicine New Vision University Tbilisi Georgia

Takotsubo cardiomyopathy is a heart condition that is widely known to be caused by stress. It presents with symptoms that are similar to a myocardial infarction even though the coronary arteries are clear. This case report details the clinical characteristics, diagnostic assessment, and management plan of a 55-year-old male patient with a past medical history of alcoholism who arrived at the emergency department with the typical symptoms of acute pancreatitis. The case demonstrates the progression of Takotsubo cardiomyopathy, which was triggered by acute pancreatitis in the context of alcoholism, and underlines the significance of early detection and management to enhance the patient’s outcomes.

关键词： Takotsubo Cardiomyopathy Acute Pancreatitis alcoholism Epigastric Pain

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Challenges to establishing and maintaining kidney transplantation programs in developing countries:What are the coping strategies?

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World Journal of Methodology 2024年第2期14卷 1-16页

作者： Rabea ahmed Gadelkareem Amr Mostafa Abdelgawad Nasreldin Mohammed Mohammed ali Zarzour Mahmoud khalil ahmed Reda Hisham Mokhtar Hammouda Department of Urology Assiut Urology and Nephrology HospitalFaculty of MedicineAssiut UniversityAssiut 71515Egypt

Kidney transplantation(KT)is the optimal form of renal replacement therapy for patients with end-stage renal ***,this health service is not available to all patients,especially in developing *** deceased donor KT programs are mostly absent,and the living donor KT centers are ***-center studies presenting experiences from developing countries usually report a variety of *** review addresses these challenges and the opposing strategies by reviewing the single-center experiences of developing *** financial challenges hamper the infrastructural and material availability,coverage of transplant costs,and qualification of medical *** sociocultural challenges influence organ donation,equity of beneficence,and regular follow-up *** interests and motives for transplantation may result from high medicolegal responsibilities in KT practice,intense potential psychosocial burdens,complex qualification protocols,and low productivity or compensation for KT *** medical literacy about KT advantages is prevalent among clinicians,patients,and the *** inefficient organizational and regulatory oversight is translated into inefficient healthcare systems,absent national KT programs and registries,uncoordinated job descriptions and qualification protocols,uncoordinated on-site investigations with regulatory constraints,and the prevalence of commercial KT *** challenges resulted in noticeable differences between KT services in developed and developing *** coping strategies can be summarized in two main mechanisms:The first mechanism is maximizing the available resources by increasing the rates of living kidney donation,promoting the expertise of medical personnel,reducing material consumption,and supporting the establishment and maintenance of KT *** latter warrants the expansion of the public sector and the elimination of non-ethical KT *** second mechanism is recru

关键词： Challenges Coping strategies Developing countries Kidney transplantation Low resources Single-center

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Off-Pump Coronary Artery Bypass Grafting in Patients with Left Ventricular Dysfunction: Short-Term Results from a Single Center in Bangladesh

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World Journal of Cardiovascular Surgery 2024年第9期14卷 145-156页

作者： Muhit Abdullah Md. Abir Tazim Chowdhury Satyajit Sharma Rehana Akther Munama Magdum Munjerin Refat Synthee Md. Zafar-al-Nimari Saikat Das Gupta saleh ahmed Samir Kumar Biswas M. Quamrul Islam Talukder Farooque ahmed Department of Cardiac Surgery National Heart Foundation Hospital and Research Institute (NHFH&RI) Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Dhaka Bangladesh Ispahani Islamia Eye Institute & Hospital Khamarbari Dhaka Bangladesh National Institute of Preventive and Social Medicine Dhaka Bangladesh Square Hospital Dhaka Bangladesh

Background: Off-pump coronary artery bypass grafting (OPCAB) is considered a safer alternative to on-pump surgery, especially in patients with left ventricular dysfunction (LVD). Objectives: This study assessed short-term outcomes and functional improvements in LVD patients post-OPCAB. Methods: The study included 200 coronary artery disease patients who underwent isolated off-pump coronary artery bypass grafting (OPCAB) at the National Heart Foundation Hospital and Research Institute between January 2019 and June 2020. Patients were categorized into Group 1, with a left ventricular ejection fraction (LVEF) of 30% - 39%, and Group 2, with an LVEF of 40% or higher. Echocardiographic assessments of left ventricular dimensions and ejection fraction were performed preoperatively, at discharge, and one month postoperatively. Results: In Group 1, preoperative left ventricular internal dimensions during diastole (LVIDd) and systole (LVIDs) were 53.48 ± 4.40 mm and 44.23 ± 3.93 mm, respectively, with a left ventricular ejection fraction (LVEF) of 35.28% ± 2.26%. At discharge, these values improved to 51.58 ± 4.04 mm (LVIDd), 41.23 ± 5.30 mm (LVIDs), and 39.25% ± 3.75% (LVEF). One month postoperatively, further improvements were observed: 46.29 ± 3.76 mm (LVIDd), 37.45 ± 3.68 mm (LVIDs), and 43.22% ± 4.67% (LVEF). Group 2 showed similar positive outcomes, with preoperative values of 47.09 ± 5.06 mm (LVIDd), 35.11 ± 5.25 mm (LVIDs), and 50.13% ± 7.25% (LVEF), improving to 42.37 ± 4.18 mm (LVIDd), 31.05 ± 4.19 mm (LVIDs), and 55.33% ± 7.05% (LVEF) at one month postoperatively. Both groups demonstrated significant improvements in left ventricular function and NYHA class, with most patients moving from class III/IV to I/II. Complications were minimal, and no mortality was observed. Conclusion: OPCAB is safe and effective for patients with LVEF 30% - 39% and LVEF ≥ 40%, providing significant short-term functional improvements without increased risk.

关键词： Off-Pump Coronary Artery Bypass Grafting Left Ventricular Dysfunction (LVD) Short-Term Outcomes

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