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Robust Malicious Executable Detection Using Host-Based Machine Learning Classifier

Computers, Materials & Continua 2024年第4期79卷 1419-1439页

作者： khaled soliman Mohamed Sobh Ayman M.Bahaa-Eldin Department of Computer and Systems Engineering Ain Shams UniversityCairo11517Egypt Department of Computer Engineering Technology ElSewedy University of TechnologyCairo44629Egypt

The continuous development of cyberattacks is threatening digital transformation endeavors worldwide and leadsto wide losses for various organizations. These dangers have proven that signature-based approaches are insufficientto prevent emerging and polymorphic attacks. Therefore, this paper is proposing a Robust Malicious ExecutableDetection (RMED) using Host-based Machine Learning Classifier to discover malicious Portable Executable (PE)files in hosts using Windows operating systems through collecting PE headers and applying machine learningmechanisms to detect unknown infected files. The authors have collected a novel reliable dataset containing 116,031benign files and 179,071 malware samples from diverse sources to ensure the efficiency of RMED approach.The most effective PE headers that can highly differentiate between benign and malware files were selected totrain the model on 15 PE features to speed up the classification process and achieve real-time detection formalicious executables. The evaluation results showed that RMED succeeded in shrinking the classification timeto 91 milliseconds for each file while reaching an accuracy of 98.42% with a false positive rate equal to 1.58. Inconclusion, this paper contributes to the field of cybersecurity by presenting a comprehensive framework thatleverages Artificial Intelligence (AI) methods to proactively detect and prevent cyber-attacks.

关键词： Portable executable malware intrusion detection cybersecurity zero-day threats Host IntrusionDetection System(HIDS) machine learning Anomaly-based Intrusion Detection System(AIDS) deep learning

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Life Time Attributable Cancer Risk Estimated Using Scanner Reported Dose Length Product during Chest Computed Tomography Imaging in Young Children

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Open Journal of Radiology 2024年第2期14卷 74-82页

作者： Mousa Bakkari khaled soliman Abdullah Alrushoud Marwan Fahad Alosaimi Hanaa Alsheikh Abdelwahed Alhejaili Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia Radiogiadnostic and Medical Imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia

This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coefficients multiplying the widely available scanner registered dose length products (DLP) displayed on the CT console and hence calculating the Effective Dose (ED). The ED is then multiplied by the International Commission on Radiological Protection (ICRP) published risk factor for LAR. The obtained LAR values are compared with the international literature. Factors that may affect the LAR value are reported and discussed. The study included one hundred twenty five chest CT examinations for both males and females aged from less than one year to fifteen years. The patients reported data are from one single medical institution and using two CT scanners from June 2022 to December 2023. The results of this study may serve as benchmark for institutional radiation dose reference levels and risk estimation.

关键词： Cancer Risk LAR Chest CT Pediatric Radiology Radiation Dose DLP

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Organ and function preservation in gastrointestinal cancer: Current and future perspectives on endoscopic ablation

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World Journal of Gastrointestinal Endoscopy 2024年第6期16卷 282-291页

作者： Youssef Yousry soliman Megan soliman Shravani Reddy James Lin Toufic Kachaamy Department of Gastroenterology City of Hope PhoenixGoodyearAZ 85338United States Department of Medicine Medical ConsultingGoodyearAZ 85395United States Department of Gastroenterology University of California IrvineIrvineCA 92697United States Department of Gastroenterology City of Hope National Medical CenterDuarteCA 91010United States

The escalating prevalence of gastrointestinal cancers underscores the urgency for transformative approaches.Current treatment costs amount to billions of dollars annually,combined with the risks and comorbidities associated with invasive surgery.This highlights the importance of less invasive alternatives with organ preservation being a central aspect of the treatment paradigm.The current standard of care typically involves neoadjuvant systemic therapy followed by surgical resection.There is a growing interest in organ preservation approaches by way of minimizing extensive surgical resections.Endoscopic ablation has proven to be useful in precursor lesions,as well as in palliative cases of unrese-ctable disease.More recently,there has been an increase in reports on the utility of adjunct endoscopic ablative techniques for downstaging disease as well as contributing to non-surgical complete clinical response.This expansive field within endoscopic oncology holds great potential for advancing patient care.By addressing challenges,fostering collaboration,and embracing technological advancements,the gastrointestinal cancer treatment paradigm can shift towards a more sustainable and patient-centric future emphasizing organ and function preservation.This editorial examines the evolving landscape of endoscopic ablation strategies,emphasizing their potential to improve patient outcomes.We briefly review current applications of endoscopic ablation in the esophagus,stomach,duodenum,pancreas,bile ducts,and colon.

关键词： Gastrointestinal cancer Endoscopic ablation Organ preservation Complete clinical response Neoadjuvant therapy Endoscopic oncology Palliative treatment

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Radiation Dose Survey of Pediatric Chest Computed Tomography Examinations: A Local Diagnostic Reference Levels Approach to Patient Safety

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Journal of Applied Mathematics and Physics 2023年第7期11卷 2137-2143页

作者： Turki Alruwaili Bani Alsubaie Salman Altimyat khaled soliman Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia Radiodiagnostic and Medical Imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia

Objectives: The aim of this work was to initially establish both age and weight driven pediatric diagnostic reference levels (DRLs) for chest computed tomography (CT) examinations performed at tertiary care medical institution. Another aim was to compare the presented data with internationally published ones. This initial data shall serve as basis for establishing a national DRLs values for pediatric diagnostic CT examinations. Methods: Dosimetric indexes were collected for the chest examination for 93 patients during the past 2 years in a tertiary care medical city. Results: The results are within and below the international reported levels for chest CT in several countries. Conclusion: Continuous monitoring of the radiation doses received by the patients in computed tomography is continuous and ongoing process in order to ensure compliance and to optimize clinical imaging protocols. More extensive data acquisition and analysis are required to allow better understanding of the contributing factors leading to less patient radiation dose while preserving the clinical image quality. .

关键词： Computed Tomography Chest CT Diagnostic Reference Levels Monitoring Optimization

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Relationship between Whole Body Iodine-131 Effective Half-Life and Estimated Glomerular Filtration Rate for Papillary Thyroid Cancer Patients Undergoing Radioactive Iodine Therapy

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Journal of Applied Mathematics and Physics 2023年第8期11卷 2472-2479页

作者： Asim Abualnaja Hanaa Alsheikh khaled soliman Meshal Alnefaie Abdulraheem Alsheri Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia Radiodiagnostics and Medical Imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia

Background: The aim of this work was to examine the relationship between the estimated glomerular filtration rate (eGFR) as indicator of renal efficiency potentially related to the ability to release radioactive iodine from the patients bodies and the radioactive iodine whole body effective half-life (WBEHL) defined as the time taken for the administered activity to decay to half of its value for papillary thyroid cancer (PTC) patients undergoing radioactive iodine therapy (RAIT) in a tertiary care medical Centre. Methods: This retrospective observational study included seventy nine patients, sixty females and nineteen males. The patients were divided in two subgroups, those who have WBEHL of less than 11 hours (n = 51) and those with more than 11 (n = 28) hrs based on k-means clustering technique. Results: Analysis of variance (ANOVA) was used to find out if there is a statistically significant difference between the two subgroups Conclusion: There was not a statistically significant difference between the short and the longer WBEHL patients’ groups analyzed in this study. .

关键词： GFR Thyroid Cancer Radioactive Iodine Therapy Renal Function

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Analysis of Local Diagnostic Reference Levels for Pediatric Patients Undergoing 18F-FDG PET/CT Imaging for Oncology

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Journal of Applied Mathematics and Physics 2023年第7期11卷 2144-2155页

作者： Saad Alqahtani khaled soliman Saad Alotaibi khaled Alnofaie Abdullah Alahmari Fahad Alyahya Abdullah Albdullah Rashed Alharbi Radiodiagnostic and Medical Imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia

Background: The PET/CT imaging studies have two doses components the dose from the PET radiopharmaceutical and the other from the low dose CT used for PET images attenuation correction. We have one PET/CT scanner at our institution a Philips Time of Flight scanner. Our local patient’s radiation protection rules requires continuous assessment of radiation doses delivered to our patients. Purposes: The objectives of this study are to develop a weight- based facility DRLs for paediatric F-18-FDG PET-CT imaging for oncology in a large tertiary hospital and to determine whether the calculated DRLs compares with internationally published DRLs. Materials & Methods: Radiation dose data and patient demographics of two-hundreds and sixteen paediatric PET-CT oncology patients imaging procedures from one large tertiary hospital were selected and analysed in order to establish a facility paediatric DRLs. Statistical analysis was performed. Results: The PET dose reference levels ranged between [62 - 525] MBq of injected activity for a range of pediatric age groups. The CTDIvol values were between 3.5 and 16.5 mGy for all age groups. Comparison with current EANM and SNMMI recommendations of patient’s dose are discussed. Conclusion: Our pediatric PET/CT reference levels are higher than the ones reported internationally with notable variations. .

关键词： Diagnostic Reference Levels PET/CT 18-F-FDG Pediatric Radiation Dose CTDIvol Oncology

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A Hybrid Cybersecurity Algorithm for Digital Image Transmission over Advanced Communication Channel Models

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Computers, Materials & Continua 2024年第4期79卷 201-241页

作者： Naglaa F.soliman Fatma E.Fadl-Allah Walid El-Shafai Mahmoud I.Aly Maali Alabdulhafith Fathi E.Abd El-Samie Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Electronics and Communications Faculty of EngineeringZagazig UniversityZagazig44519Egypt Security Engineering Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

The efficient transmission of images,which plays a large role inwireless communication systems,poses a significant challenge in the growth of multimedia technology.High-quality images require well-tuned communication standards.The Single Carrier Frequency Division Multiple Access(SC-FDMA)is adopted for broadband wireless communications,because of its low sensitivity to carrier frequency offsets and low Peak-to-Average Power Ratio(PAPR).Data transmission through open-channel networks requires much concentration on security,reliability,and integrity.The data need a space away fromunauthorized access,modification,or deletion.These requirements are to be fulfilled by digital image watermarking and encryption.This paper ismainly concerned with secure image communication over the wireless SC-FDMA systemas an adopted communication standard.It introduces a robust image communication framework over SC-FDMA that comprises digital image watermarking and encryption to improve image security,while maintaining a high-quality reconstruction of images at the receiver side.The proposed framework allows image watermarking based on the Discrete Cosine Transform(DCT)merged with the Singular Value Decomposition(SVD)in the so-called DCT-SVD watermarking.In addition,image encryption is implemented based on chaos and DNA encoding.The encrypted watermarked images are then transmitted through the wireless SC-FDMA system.The linearMinimumMean Square Error(MMSE)equalizer is investigated in this paper to mitigate the effect of channel fading and noise on the transmitted images.Two subcarrier mapping schemes,namely localized and interleaved schemes,are compared in this paper.The study depends on different channelmodels,namely PedestrianAandVehicularA,with a modulation technique namedQuadratureAmplitude Modulation(QAM).Extensive simulation experiments are conducted and introduced in this paper for efficient transmission of encrypted watermarked images.In addition,different variants of SC-FDMA based on the Discrete Wavelet Transform(DWT),Discre

关键词： Cybersecurity applications image transmission channel models modulation techniques watermarking and encryption

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A review of concrete bridge surface defect detection based on deep learning

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Optoelectronics Letters 2024年

作者： LIAO Yanna HUANG Chaoyang Abdel-Hamid soliman School of Electronic Engineering Xi'an University of Posts and Telecommunications School of Digital Technology Innovation and Business Staffordshire University

The detection of surface defects in concrete bridges using deep learning is of significant importance for reducing operational risks， saving maintenance costs， and driving the intelligent transformation of bridge defect detection. In contrast to the subjective and inefficient manual visual inspection， deep learning-based algorithms for concrete defect detection exhibit remarkable advantages， emerging as a focal point in recent research. This paper comprehensively analyzes the research progress of deep learning algorithms in the field of surface defect detection in concrete bridges in recent years. It introduces the early detection methods for surface defects in concrete bridges and the development of deep learning. Subsequently， it provides an overview of deep learning-based concrete bridge surface defect detection research from three aspects: image classification， object detection， and semantic segmentation. The paper summarizes the strengths and weaknesses of existing methods and the challenges they face. Additionally， it analyzes and prospects the development trends of surface defect detection in concrete bridges.

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Relationship between Patient-Dependent Parameters and Radiation Dose Rates Measured around Patients Undergoing PET/CT Imaging Using <sup>18</sup>F-FDG

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2018年第3期7卷 403-413页

作者： khaled soliman Saad Al Qahtani Ahmed Alenezi Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia Radiodiagnostic and Medical Imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia Faculty of Applied Medical Sciences King Saud University Riyadh Saudi Arabia

Objectives: Patients undergoing 18F-FDG PET/CT imaging are considered external radiation sources. Accurate dose rate estimates are important for conducting realistic risk assessments and performing dose reconstruction in cases of accidental exposures. The patient radiation self-attenuation factor is assumed to be a function of the patient’s body size metrics, but we can use these metrics to predict the dose rate around the patients with accuracy. The objective of this work was first to measure the patient attenuation factor by performing direct dose rate measurements from patients undergoing PET/CT imaging studies using 18F-FDG. The second objective was to study the possible correlation between the measured dose rate constant per unit activity from the patients and their body size metrics;five metrics were tested in this work. The last objective was to measure the patients’ voiding factor. Methods: We have measured dose rates at one meter from 57 patients and noted the patient’s height (H), weight (W) and calculated patient size metrics namely: Equivalent Cylindrical Diameter (ECD), Equivalent Spherical Diameter (ESD) and the Body Mass Index (BMI). Results: The measured average dose rate was 92.2 ± 14 μSv·h-1·GBq-1 measured at one meter. Therefore, the dose rate constant of 92 μSv·h-1·GBq-1 proposed by the AAPM, TG-108 report is adequate for radiation protection purposes. There was no statistically significant correlation between the dose rate constant per unit activity and the patient body size metrics. We have measured a patient voiding factor of 0.89 ± 0.06 in comparison with 0.85 recommended by the AAPM. Conclusions: The presented data can be used by medical physicist working in nuclear medicine in formulating more accurate risk estimations resulting from radiation exposure from patients undergoing 18F-FDG PET/CT imaging.

关键词： FDG Measured Dose Rate Patient Voiding Factor Patient Attenuation Factor Patient Size

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<i>In-Vivo</i>Dosimetry Method for Measuring Peak Surface Dose Using Radiochromic Films during Computed Tomography Scanning of the Sinus

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2018年第2期7卷 151-159页

作者： khaled soliman Salman Altimyat Abdullah Alrushoud Ahmed Alenezi Mohammed Alkhorayef Medical Physics Department Prince Sultan Military Medical City Riyadh KSA Department of Radiological Sciences College of Applied Medical Sciences King Saud University Riyadh KSA

Purpose: During computed tomography (CT) helical scanning mode the patient surface dose distribution is assumed to be non-uniform, therefore point dose measurement methods may lead to imprecise estimation of the radiation dose received by the patient skin in particular. We have used XRQA2 films as in-vivo dosimeters to measure the entrance skin dose during sinus exams. Methods: The films were placed under the patient head rest in order to sample the entrance surface dose in-vivo. We have performed in-vivo film irradiation on 23 patients in this study to verify the clinical suitability of the method and were found adequate. Results: The measured average ESD in the sinus exam was 11.7 ± 1.0 mGy, the PSD was 15.7 ± 1.7 mGy and the CTDI(vol) was 13.3 ± 0.1 mGy. The ratio of ESD/CTDI(vol) and PSD/CTDI(vol) was 0.88 and 1.18 respectively. The results indicate that the scanner registered CTDI(vol) underestimates the PSD and in the same time it overestimates the ESD by 18% and 13.6% respectively. Conclusion: The observed differences between the ESD, PSD and CTDI(vol) although seem small for the radiation dose range measured during CT of the sinus [13.2 - 13.4] mGy, but important for the medical physicist to know, since monitoring of patients’ doses from CT examinations is becoming more mandatory. The use of radiochromic film as in-vivo dosimeter does not interfere with the clinical radiological exam and does not produce any image artifacts. The method can be used to study other CT examinations specially the ones with large beam width, high pitch factor and high dose exams. The method allows measurement of the peak skin dose, examination of the CT dose profile and the 2D dose distribution in the XZ plan.

关键词： Radiochromic Films Sinus CT In-Vivo Dosimetry CTDI(Vol) Entrance Surface Dose

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