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Journal of Contemporary Educational Research 2024年第8期8卷 88-94页

作者： keren pan Technological University of the Philippines Manila1000Philippines Nanning Vocational and Technical University Nanning 530008Guangxi Zhuang Autonomous RegionChina

Reinforcement theory is a behavioral psychology theory proposed by Skinner,which has been widely applied in various fields such as management and *** reinforcement and negative reinforcement are the two types of *** adopting these two different reinforcement methods appropriately,human behavior can develop in a positive *** the review stage of English teaching and learning in Chinese higher vocational and technical colleges,the use of different reinforcement methods based on various classes,individuals,conditions,and environments can effectively promote or change the behavior of teachers and students,thereby improving the effectiveness of the review.

关键词： Reinforcement theory Higher vocational and technical colleges English teaching and learning Review Effectiveness

Large circuit models: opportunities and challenges

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Science China(Information Sciences) 2024年第10期67卷 25-66页

作者： Lei CHEN Yiqi CHEN Zhufei CHU Wenji FANG Tsung-Yi HO Ru HUANG Yu HUANG Sadaf KHAN Min LI Xingquan LI Yu LI Yun LIANG Jinwei LIU Yi LIU Yibo LIN Guojie LUO Hongyang pan Zhengyuan SHI Guangyu SUN Dimitrios TSARAS Runsheng WANG Ziyi WANG Xinming WEI Zhiyao XIE Qiang XU Chenhao XUE Junchi YAN Jun YANG Bei YU Mingxuan YUAN Evangeline F.Y.YOUNG Xuan ZENG Haoyi ZHANG Zuodong ZHANG Yuxiang ZHAO Hui-Ling ZHEN Ziyang ZHENG Binwu ZHU keren ZHU Sunan ZOU Huawei Noah’s Ark Lab School of Integrated Circuits Peking University Faculty of Electrical Engineering and Computer Science Ningbo University Department of Electronic and Computer Engineering Hong Kong University of Science and Technology Department of Computer Science and Engineering The Chinese University of Hong Kong School of Integrated Circuits Southeast University Huawei HiSilicon Peng Cheng Laboratory School of Computer Science Peking University School of Microelectronics State Key Laboratory of Integrated Chips and System Fudan University School of Artificial Intelligence Shanghai Jiao Tong University

Within the electronic design automation(EDA) domain, artificial intelligence(AI)-driven solutions have emerged as formidable tools, yet they typically augment rather than redefine existing methodologies. These solutions often repurpose deep learning models from other domains, such as vision, text, and graph analytics, applying them to circuit design without tailoring to the unique complexities of electronic circuits. Such an “AI4EDA” approach falls short of achieving a holistic design synthesis and understanding,overlooking the intricate interplay of electrical, logical, and physical facets of circuit data. This study argues for a paradigm shift from AI4EDA towards AI-rooted EDA from the ground up, integrating AI at the core of the design process. Pivotal to this vision is the development of a multimodal circuit representation learning technique, poised to provide a comprehensive understanding by harmonizing and extracting insights from varied data sources, such as functional specifications, register-transfer level(RTL) designs, circuit netlists,and physical layouts. We champion the creation of large circuit models(LCMs) that are inherently multimodal, crafted to decode and express the rich semantics and structures of circuit data, thus fostering more resilient, efficient, and inventive design methodologies. Embracing this AI-rooted philosophy, we foresee a trajectory that transcends the current innovation plateau in EDA, igniting a profound “shift-left” in electronic design methodology. The envisioned advancements herald not just an evolution of existing EDA tools but a revolution, giving rise to novel instruments of design-tools that promise to radically enhance design productivity and inaugurate a new epoch where the optimization of circuit performance, power, and area(PPA) is achieved not incrementally, but through leaps that redefine the benchmarks of electronic systems' capabilities.

关键词： AI-rooted EDA large circuit models (LCMs) multimodal circuit representation learning circuit optimization

Quantum second-order optimization algorithm for general polynomials

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Science China(Physics,Mechanics & Astronomy) 2021年第10期64卷 54-63页

作者： pan Gao keren Li Shijie Wei Gui-Lu Long State Key Laboratory of Low-Dimensional Quantum Physics and Department of Physics Tsinghua UniversityBeijing 100084China Shenzhen JL Computational Science and Applied Research Institute Shenzhen 518109China Beijing Academy of Quantum Information Sciences Beijing 100193China Beijing National Research Center for Information Science and Technology and School of Information Tsinghua UniversityBeijing 100084China Frontier Science Center for Quantum Information Beijing 100084China

Quantum optimization algorithms can outperform their classical counterpart and are key in modern technology. The second-order optimization algorithm(the Newton algorithm) is a critical optimization method, speeding up the convergence by employing the second-order derivative of loss functions in addition to their first derivative. Here, we propose a new quantum second-order optimization algorithm for general polynomials with a computational complexity of O(poly(log d)). We use this algorithm to solve the nonlinear equation and learning parameter problems in factorization machines. Numerical simulations show that our new algorithm is faster than its classical counterpart and the first-order quantum gradient descent algorithm. While existing quantum Newton optimization algorithms apply only to homogeneous polynomials, our new algorithm can be used in the case of general polynomials, which are more widely present in real applications.

关键词： quantum computation quantum algorithm optimization

基于Markov过程天气预测的共享单车调度优化研究

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温州大学学报（自然科学版） 2024年第3期45卷 30-41页

作者：孟英豪王启阳王柯人魏来陈益丰潘晓铭温州大学机电工程学院浙江温州325035

针对某大学城共享单车资源分配不平衡问题,建立了与调度成本和用户满意度相关的单目标数学规划模型,对现有共享单车调度策略进行分析,并制定改善方案.通过调查问卷分析单车调度过程中存在的问题,利用Python获取单车的相关数据.在此基础... 详细信息

针对某大学城共享单车资源分配不平衡问题,建立了与调度成本和用户满意度相关的单目标数学规划模型,对现有共享单车调度策略进行分析,并制定改善方案.通过调查问卷分析单车调度过程中存在的问题,利用Python获取单车的相关数据.在此基础上,基于齐次Markov过程对天气状况进行预测,采用LSTM时间序列对区域内未来单车数量的变化情况进行预测,利用遗传算法求解最优调度路径和调度数量,提出优化方案.通过敏感性分析验证本文所提方案的可行性.结果表明,优化后的调度方案缩短了单次调度时间并提高了用户的满意度,对共享单车管理部门具有指导意义.

关键词：单车调度单目标规划 Markov过程遗传算法 LSTM 敏感性分析

Profiling the Bisecting N-acetylglucosamine Modification in Amniotic Membrane via Mass Spectrometry

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Genomics, Proteomics & Bioinformatics 2022年第4期20卷 648-656页

作者： Qiushi Chen Yuanliang Zhang keren Zhang Jie Liu Huozhen pan Xinran Wang Siqi Li Dandan Hu Zhilong Lin Yun Zhao Guixue Hou Feng Guan Hong Li Siqi Liu Yan Ren BGI-Shenzhen Shenzhen 518083China Joint International Research Laboratory of Glycobiology and Medical Chemistry College of Life SciencesNorthwest UniversityXi’an 710069China Shenzhen Seventh People's Hospital Shenzhen 518081China Institute of Interdisciplinary Integrative Medicine Research Shanghai University of Traditional Chinese MedicineShanghai 201203China

Bisecting N-acetylglucosamine(GlcNAc),a GlcNAc linked to the coreβ-mannose residue via aβ1,4 linkage,is a special type of N-glycosylation that has been reported to be involved in various biological processes,such as cell adhesion and fetal *** N-glycan structure is abundant in human trophoblasts,which is postulated to be resistant to natural killer cellmediated cytotoxicity,enabling a mother to nourish a fetus without *** this study,we hypothesized that the human amniotic membrane,which serves as the last barrier for the fetus,may also express bisected-type *** test this hypothesis,glycomic analysis of the human amniotic membrane was performed,and bisected N-glycans were ***,our proteomic data,which have been previously employed to explore human missing proteins,were analyzed and the presence of bisecting GlcNAc-modified peptides was confirmed.A total of 41glycoproteins with 43 glycopeptides were found to possess a bisecting GlcNAc,and 25 of these glycoproteins were reported to exhibit this type of modification for the first *** results provide insights into the potential roles of bisecting GlcNAc modification in the human amniotic membrane,and can be beneficial to functional studies on glycoproteins with bisecting GlcNAc modifications and functional studies on immune suppression in human placenta.

关键词： Glycan Glycoprotein Amniotic membrane Bisecting N-acetylglucosamine Mass spectrometry

Challenges and opportunities toward fully automated analog layout design

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Journal of Semiconductors 2020年第11期41卷 71-80页

作者： Hao Chen Mingjie Liu Xiyuan Tang keren Zhu Nan Sun David Z.pan Department of Electrical and Computer Engineering The University of Texas at AustinAustin 78712USA

Realizing the layouts of analog/mixed-signal(AMS)integrated circuits(ICs)is a complicated task due to the high design flexibility and sensitive circuit *** with the advancements of digital IC layout automation,analog IC layout design is still heavily manual,which leads to a more time-consuming and error-prone *** recent years,significant progress has been made in automated analog layout design with emerging of several open-source *** paper firstly reviews the existing state-of-the art AMS layout synthesis frameworks with focus on the different approaches and their individual *** then present recent research trends and opportunities in the ***,we summaries the paper with open questions and future directions for fully-automating the analog IC layout.

关键词： VLSI integrated circuit ASIC EDA analog ic design physical design

Cortical thickness abnormalities in patients with first episode psychosis:a meta-analysis of psychoradiologic studies and replication in an independent sample

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Psychoradiology 2021年第4期1卷 185-198页

作者： keren Wen Youjin Zhao Qiyong Gong Ziyu Zhu Qian Li Nanfang pan Shiqin Fu Joaquim Radua Eduard Vieta Poornima Kumar Graham J.Kemp Bharat B.Biswal Huaxi MR Research Center(HMRRC) Department of RadiologyWest China Hospital of Sichuan UniversityChengdu 610041SichuanChina Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengdu 610041SichuanChina Functional and Molecular Imaging Key Laboratory of Sichuan Province Chengdu 610041SichuanChina Institut d’Investigacions Biom`ediques August Pi i Sunyer(IDIBAPS) Mental Health Research Networking Center(CIBERSAM)Barcelona 08036CataloniaSpain Centre for Psychiatric Research and Education Department of Clinical NeuroscienceKarolinska InstitutetSolna 171-77StockholmSweden Department of Psychosis Studies Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK Barcelona Bipolar Disorders and Depressive Unit Hospital ClinicInstitute of NeurosciencesUniversity of BarcelonaBarcelona 08036CataloniaSpain Center for Depression Anxiety and Stress ResearchMcLean HospitalBelmont 02478MAUSA Department of Psychiatry Harvard Medical SchoolBoston 02115MAUSA Liverpool Magnetic Resonance Imaging Centre(LiMRIC)and Institute of Life Course and Medical Sciences University of LiverpoolLiverpool L693GEUK Department of Biomedical Engineering New Jersey Institute of TechnologyNewark 07102NJUSA The Clinical Hospital of Chengdu Brain Science Institute MOE Key Laboratory for NeuroinformationUniversity of Electronic Science and Technology of ChinaChengdu 610054SichuanChina

Background:Abnormalities of cortical thickness(CTh)in patients with their first episode psychosis(FEP)have been frequently reported,but findings are ***:To define the most consistent CTh changes in patients with FEP by meta-analysis of publishedwholebrain ***:The meta-analysis used seed-based dmapping(SDM)software to obtain the most prominent regional CTh changes in FEP,and meta-regression analyses to explore the effects of demographics and clinical *** meta-analysis results were verified in an independent sample of 142 FEP patients and 142 age-and sex-matched healthy controls(HCs),using both a vertex-wise and a region of interest analysis,with multiple comparisons ***:The meta-analysis identified lower CTh in the rightmiddle temporal cortex(MTC)extending to superior temporal cortex(STC),insula,and anterior cingulate cortex(ACC)in FEP compared with *** significant correlations were identified between CTh alterations and demographic or clinical *** results were replicated in the independent dataset ***:This study identifies a robust pattern of cortical abnormalities in FEP and extends understanding of gray matter abnormalities and pathological mechanisms in FEP.

关键词： psychoradiology first episode psychosis early psychosis cortical thickness meta-analysis seed-based d mapping

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基于序列图像时间稳定性特征的背景估计技术

清华大学学报（自然科学版） 2005年第5期45卷 601-605页

作者：郑军张伟马兆瑞施克仁潘际銮清华大学机械工程系先进成形制造重点实验室北京100084

针对背景的缓变特性和实时图像处理的需求,该文提出了一种基于序列图像时间稳定性特征的背景估计技术。采用一个时间矩阵来监视序列图像的稳定性特征,利用背景在时间上的缓变特性来实现对背景的提取和更新。结果表明:该方法具有简单有... 详细信息

针对背景的缓变特性和实时图像处理的需求,该文提出了一种基于序列图像时间稳定性特征的背景估计技术。采用一个时间矩阵来监视序列图像的稳定性特征,利用背景在时间上的缓变特性来实现对背景的提取和更新。结果表明:该方法具有简单有效、实时性能好、内存消耗少、背景提取速度快等特点,并对突变背景具有自动感知能力;时间矩阵对于运动目标的分布和轨迹分析也具有参考价值;该方法特别适合静止摄像机的背景估计,在背景配准后也适用于移动摄像机的背景估计。

关键词：图像处理背景估计序列图像运动目标

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虾青素的生理功能及其制剂技术的研究进展

河南工业大学学报（自然科学版） 2019年第6期40卷 123-129页

作者：潘丽常振刚陈娟谷克仁河南工业大学粮油食品学院河南郑州450001 河南金谷实业发展有限公司河南郑州450003 中央储备粮郑州直属库有限公司河南郑州450001

虾青素具有抗氧化、增强免疫力、抗肿瘤、抗炎症以及光保护等生理功能,已引起科研人员的极大关注。然而,虾青素性质不稳定,在水中溶解性较差,生物利用率低,使得虾青素在应用中受到极大的限制,选择合适的制剂技术以拓宽虾青素的应用范围... 详细信息

虾青素具有抗氧化、增强免疫力、抗肿瘤、抗炎症以及光保护等生理功能,已引起科研人员的极大关注。然而,虾青素性质不稳定,在水中溶解性较差,生物利用率低,使得虾青素在应用中受到极大的限制,选择合适的制剂技术以拓宽虾青素的应用范围显得尤为重要。综述了虾青素的生理功能,对近年来国内外虾青素制剂技术的发展进行了归纳介绍。

关键词：虾青素生理功能制剂稳定性水溶性生物利用率

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溶血磷脂的制备、分离、检测及应用研究进展

中国油脂 2018年第6期43卷 132-136,143页

作者：李招谷克仁张海臣潘丽康世宗河南工业大学化学化工与环境学院郑州450001 吉林工程技术学院吉林四平136001 哈尔滨商业大学食品工程学院哈尔滨150076

溶血磷脂(Lysophospholipids)是磷脂在自然降解或磷脂酶的作用下从1位或2位酯键断裂产生的单链脂肪酰磷脂衍生物,是一类仅含有1条脂肪酸链的甘油磷脂。溶血磷脂具有良好的表面活性、乳化性等性能,应用于食品、医药等行业,也作为信号分... 详细信息

溶血磷脂(Lysophospholipids)是磷脂在自然降解或磷脂酶的作用下从1位或2位酯键断裂产生的单链脂肪酰磷脂衍生物,是一类仅含有1条脂肪酸链的甘油磷脂。溶血磷脂具有良好的表面活性、乳化性等性能,应用于食品、医药等行业,也作为信号分子参与生命活动。我国在溶血磷脂方面的研究未达到世界先进水平。综述了溶血磷脂的制备方法、分离提取方法、检测方法以及应用的研究进展,以期对溶血磷脂的研究有所帮助。

关键词：溶血磷脂制备分离提取检测应用