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Intra-cardiac distribution of late gadolinium enhancement in cardiac sarcoidosis and dilated cardiomyopathy

World Journal of Cardiology 2016年第9期8卷 496-503页

作者： Makoto Sano Hiroshi Satoh kenichiro suwa Masao Saotome Tsuyoshi Urushida Hideki Katoh Hideharu Hayashi Takeji Saitoh Division of Cardiology Internal Medicine ⅢHam-mamatsu University School of Medicine Department of Emergency Medicine Hamamatsu University School of Medicine

Cardiac involvement of sarcoid lesions is diagnosed by myocardial biopsy which is frequently false-negative,and patients with cardiac sarcoidosis(CS) who have impaired left ventricular(LV) systolic function are sometimes diagnosed with dilated cardiomyopathy(DCM).Late gadolinium enhancement(LE) in magnetic resonance imaging is now a critical finding in diagnosing CS,and the novel Japanese guideline considers myocardial LE to be a major criterion of *** article describes the value of LE in patients with CS who have impaired LV systolic function,particularly the diagnostic and clinical significance of LE distribution in comparison with *** existed at all LV segments and myocardial layers in patients with CS,whereas it was localized predominantly in the midwall of basal to mid septum in those with ***(nodular),circumferential,and subepicardial and subendocardial LE distribution were highly specific in patients with CS,whereas the prevalence of striated midwall LE were high both in patients with CS and with *** sarcoidosis patients with LE have higher incidences of heart failure symptoms,ventricular tachyarrhythmia and sudden cardiac death,the analyses of extent and distribution of LE are crucial in early diagnosis and therapeutic approach for patients with CS.

关键词： Magnetic resonance imaging Late gado linium enhancement Sarcoidosis Dilated cardiomyo pathy Diagnosis

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Distribution of late gadolinium enhancement in various types of cardiomyopathies:Significance in differential diagnosis, clinical features and prognosis

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World Journal of Cardiology 2014年第7期6卷 585-601页

作者： Hiroshi Satoh Makoto Sano kenichiro suwa Takeji Saitoh Mamoru Nobuhara Masao Saotome Tsuyoshi Urushida Hideki Katoh Hideharu Hayashi Division of Cardiology Internal Medicine ⅢHamamatsu University School of Medicine

The recent development of cardiac magnetic resonance(CMR)techniques has allowed detailed analyses of cardiac function and tissue characterization with high spatial *** review characteristic CMR features in ischemic and non-ischemic cardiomyopathies(ICM and NICM),especially in terms of the location and distribution of late gadolinium enhancement(LGE).CMR in ICM shows segmental wall motion abnormalities or wall thinning in a particular coronary arterial territory,and the subendocardial or transmural *** in NICM generally does not correspond to any particular coronary artery distribution and is located mostly in the mid-wall to subepicardial *** analysis of LGE distribution is valuable to differentiate NICM with diffusely impaired systolic function,including dilated cardiomyopathy,end-stage hypertrophic cardiomyopathy(HCM),cardiac sarcoidosis,and myocarditis,and those with diffuse left ventricular(LV)hypertrophy including HCM,cardiac amyloidosis and Anderson-Fabry disease.A transient low signal intensity LGE in regions of severe LV dysfunction is a particular feature of stress *** arrhythmogenic right ventricular cardiomyopathy/dysplasia,an enhancement of right ventricular(RV)wall with functional and morphological changes of RV becomes ***,the analyses of LGE distribution have potentials to predict cardiac outcomes and response to treatments.

关键词： Cardiomyopathy Cardiac magnetic resonance Late gadolinium enhancement Cardiac function Clinical features Prognosis

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