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Hand-assisted laparoscopic restorative proctocolectomy for ulcerative colitis

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World Journal of Gastrointestinal Surgery 2016年第8期8卷 578-582页

作者： Norimitsu Shimada Hiroki Ohge Raita Yano Naoki Murao Norifumi Shigemoto Shinnosuke Uegami Yusuke Watadani kenichiro uemura Yoshiaki Murakami Taijiro Sueda Depart-ment of Surgery Hiroshima University Graduate School of Biomedical and Health Sciences

AIM To evaluate the utility of hand-assisted laparoscopic restorative proctocolectomy(HALS-RP) compared with the conventional open procedure(OPEN-RP).METHODS Fifty-one patients who underwent restorative total proctocolectomy with rectal mucosectomy and ileal pouch anal anastomosis between January 2008 and July 2015 were retrospectively *** patients in the HALS-RP group and twentyfour patients in the OPEN-RP group were *** patients who had purely laparoscopic surgery were *** total proctocolectomy was performed with mucosectomy and a hand-sewn ilealpouch-anal *** comorbidities,intraoperative factors such as blood loss and operative time,postoperative complications,and postoperative course were compared between two *** Patients in both groups were matched with regards to patient age,gender,and American Society of Anesthesiologists *** were no significant differences in extent of colitis,indications for surgery,preoperative comorbidities,and preoperative medications in the two *** median operative time for the HALS-RP group was 369(320-420) min,slightly longer than the OPEN-RP group at 355(318-421) min; this was not statistically *** loss was significantly less in HALS-RP [300(230-402) m L] compared to OPEN-RP [512(401-1162) m L,P = 0.003].Anastomotic leakage was noted in 3 patients in the HALS-RP group and 2 patients in the OPEN-RP group(13% vs 8.3%,NS).The rates of other postoperative complications and the length of hospital stay were not different between the two *** HALS-RP can be performed with less blood loss and smaller skin *** procedure is a feasible technique for total proctocolectomy for ulcerative colitis.

关键词： Hand-assisted laparoscopic surgery Ulcerative colitis Laparoscopic surgery Proctocolectomy

On Exit Time from Balls of Jump-type Symmetric Markov Processes

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Acta Mathematica Sinica,English Series 2010年第1期26卷 185-192页

作者： Toshihiro uemura Department of Mathematics Faculty of Engineering Science Kansai University

We obtain upper and lower bounds of the exit times from balls of a jump-type symmetric Markov process. The proofs are delivered separately. The upper bounds are obtained by using the Levy system corresponding to the process, while the precise expression of the （L^2-）generator of the Dirichlet form associated with the process is used to obtain the lower bounds.

关键词： symmetric Dirichlet form jump-type Markov process Levy system exit times from balls

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Eastern Asian endemic seed plant genera and their paleogeographic history throughout the Northern Hemisphere

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Journal of Systematics and Evolution 2009年第1期47卷 1-42页

作者： Steven R.MANCHESTER Kazuhiko uemura Florida Museum of Natural History University of Florida National Museum of Nature and Science

We review the fossil history of seed plant genera that are now endemic to eastern Asia. Although the majority of eastern Asian endemic genera have no known fossil record at all, 54 genera, or about 9%, are reliably known from the fossil record. Most of these are woody (with two exceptions), and most are today either broadly East Asian, or more specifically confined to Sino-Japanese subcategory rather than being endemic to the Sino-Himalayan area. Of the "eastern Asian endemic" genera so far known from the fossil record, the majority formerly occurred in Europe and/or North America, indicating that eastern Asia served as a late Tertiary or Quaternary refugium for taxa. Hence, many of these genera may have originated in other parts of the Northern Hemisphere and expanded their ranges across continents and former sea barriers when tectonic and climatic conditions al- lowed, leading to their arrival in eastern Asia. Although clear evidence for paleoendemism is provided by the gymnosperms Amentotaxus, Cathaya, Cephalotaxus, Cunninghamia, Cryptomeria, Glyptostrobus, Ginkgo, Ketel-eeria, Metasequoia, Nothotsuga, Pseudolarix, Sciadopitys, and Taiwania, and the angiosperms Cercidiphyllum, Choerospondias, Corylopsis, Craigia, Cyclocarya, Davidia, Dipelta, Decaisnea, Diplopanax, Dipteronia, Em-menopterys, Eucommia, Euscaphis, Hemiptelea, Hovenia, Koelreuteria, Paulownia, Phellodendron, Platycarya, Pteroceltis, Rehderodendron, Sargentodoxa, Schizophragma, Sinomenium, Tapiscia, Tetracentron, Toricellia, Trapella, and Trochodendron, we cannot rule out the possibility that neoendemism plays an important role especially for herbaceous taxa in the present-day flora of Asia, particularly in the Sino-Himalayan region. In addition to reviewing paleobotanical occurrences from the literature, we document newly recognized fossil occurrences that expand the geographic and stratigraphic ranges previously known for Dipelta, Pteroceltis, and Toricellia.

关键词： Cretaceous eastern Asia endemic paleobotany phytogeography Tertiary

Articulating Consciousness:Brentano and Husserl on Descriptive Analysis

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Frontiers of Philosophy in China 2020年第3期15卷 352-379页

作者： Genki uemura Graduate School of Humanities and Social Sciences Okayama UniversityOkayama 700-8530Japan

The paper aims at reconstructing the conception of descriptive analysis shared by Brentano and the early *** to this shared conception,the descriptive analysis consists in the articulation of the multi-layered part-whole structure of *** on the problem of intentional reference,the paper shows how they make different distinctions among parts of consciousness to carry out the descriptive analyses thus ***,it shows how such a difference is closely connected to the two philosophers'views on the nature of intentional reference.

关键词： Brentano Husserl descriptive psychology phenomenology method consciousness intentionality parts and wholes existential dependence

Fulminant gastrointestinal graft-versus-host disease concomitant with cytomegalovirus infection:Case report and literature review

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World Journal of Gastroenterology 2013年第4期19卷 597-603页

作者： Hidetaka Okubo Naoyoshi Nagata Naomi uemura Department of Gastroenterology and Hepatology National Center for Global Health and MedicineTokyo 162-8655Japan Department of Gastroenterology and Hepatology Kohnodai HospitalIchikawa 272-0827ChibaJapan

Here,we report a case of fulminant gastrointestinal graft-versus-host disease(GI-GVHD) with cytomegalovirus(CMV) infection in 44-year-old *** the difficulties associated with the treatment of GIGVHD and GI-CMV disease,the mucosal findings and the clinical course showed marked improvements during long-term clinical *** endoscopic findings were remarkable,with diffuse sloughing mucosa in the stomach and highly active inflammation and deep discrete ulcers throughout the *** in the CMV quantitative polymerase chain reaction results were correlated with the endoscopic mucosal findings and were useful for assessing the efficacy of the *** a definite diagnosis of GI-GVHD is generally made by endoscopy with biopsy,the gross appearance of this disease can vary depending on the *** this paper,we also conduct a literature review of patients with GI-GVHD.

关键词： Acute gastrointestinal graft-versus-host disease Allogenic stem-cell transplantation Cytomegalovirus gastrointestinal disease Cytomegaloviruspolymerase chain reaction Endoscopy

Two-dimensional self-assembly of melem and melemium cations at pH-controlled aqueous solution-Au（111） interfaces under electrochemical control

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Frontiers of Chemical Science and Engineering 2016年第2期10卷 294-300页

作者： Shinobu uemura Kenki Sakata Masashi Aono Yusuke Nakamura Masashi Kunitake Department of Advanced Materials Sciences Faculty of Engineering Kagawa University Kagawa 761-0396 Japan Graduate School of Science and Technology Kumamoto University Kumamoto 860-8555 Japan

Two-dimensional self-assembly of melem at pH-controlled aqueous solution-Au（111） interfaces has been investigated by electrochemical scanning tunneling microscopy. In the solutions with pH 〉 pKbl of melem, two ordered self-assembled structures （honeycomb and close-packed structures） and one disordered fibrillar structure were observed as a function of the surface coverage ofmelem controlled by the electrode potential. In contrast, in the acidic solution with pH 〈 pKbl of melem, only the self-assembled honeycomb network was observed in a relatively wide potential range probably due to the presence of monoprotonated melem cations. Dots attrib- uted to counteranions were frequently observed in the pores of the honeycomb network. The lack of close-packed and fibrillar structures at low pH （〈 pKbl） is attributed to ionic repulsion of melemium cations.

关键词： self-assembly scanning tunneling micro-scopy electrochemistry structural phase transition melem

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Estimating harvest costs and projecting quantities of logging residues for small-scale forestry in Nasushiobara, Tochigi Prefecture, Japan

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Journal of Forestry Research 2014年第4期25卷 965-974页

作者： Chikara Nakahata Ryo uemura Masashi Saito Kanae Kanetsuki Kazuhiro Aruga Department of Forest Science Faculty of Agriculture Utsunomiya University 350 Mine Utsunomiya 321-8505 Japan Frontier Agriscience and Technology Center Faculty of Agriculture Shinshu University Nagano 399-4598 Japan Nasunogahara Land Improvement Districts Tochigi 329-2807 Japan

We used GIS on a regional scale to estimate and compare supply potentials and costs of small-scale logging systems, a mini-forwarder and a 4-ton truck operated by private logging contractors, and manual logging and a light truck operated by individual forest own- ers, with the mechanized operational system of the Forest Owners＇ Asso- ciation. Total potential yields of timber and logging residues were esti- mated as 418,895 m3 and 254,962 m3, respectively. The economic bal- ances were estimated and available amounts were projected as supply potentials from profitable sub-compartments. As a result, available amounts of timber and logging residues were estimated at 375,466 m3 （89.9%） and 203,850 m3 （80.0%）, respectively. Because their transport expenses were lower than for other systems the most profitable sub-compartments were operated by private logging contractors who sold logging residues at a plant. The profitable sub-compartments operated by individual forest owners were few because the extracting distances were usually greater than 20 m. Raising logging residue prices from 3,000 yen·m-3 to 4,080 yen·m-3 or 6,800 yen·m-3, and establishing forest roads, which reduced some extracting distances to less than 20 m, increased the number and area of profitable sub＊compartments, and increased available amounts of logging residues.

关键词： GIS supply potentials private logging contractor individual

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Statin as a therapeutic agent in gastroenterological cancer

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World Journal of Gastrointestinal Oncology 2022年第1期14卷 110-123页

作者： Norio uemura Hiromitsu Hayashi Hideo Baba Department of Gastroenterological Surgery Graduate School of Medical SciencesKumamoto UniversityKumamoto 860-8556Japan

Statins inhibit 3-hydroxy-3-methylglutaryl-CoA reductase,the rate-limiting enzyme of the mevalonate pathway,and are widely used as an effective and safe approach handle *** mevalonate pathway is a vital metabolic pathway that uses acetyl-CoA to generate isoprenoids and sterols that are crucial to tumor growth and *** studies have indicated that statins improve patient prognosis in various *** research on the mechanisms underlying the antitumor effects of statins is *** development of new anti-cancer drugs is progressing,but increasing medical costs from drug development have become a major *** available,inexpensive and well-tolerated drugs like statins have not yet been successfully repurposed for cancer *** the cancer patients that may benefit from statins is key to improved patient *** review summarizes recent advances in statin research in cancer and suggests important considerations for the clinical use of statins to improve outcomes for cancer patients.

关键词： Statin HMG CoA reductase inhibitor Mevalonate pathway Cancer

Assessing the supercooling of fresh-cut onions at−5℃ using electrical impedance analysis

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Food Quality and Safety 2020年第2期4卷 55-58页

作者： Shoji Koide Ami Yoneyama Takahiro Orikasa Matsuo uemura Faculty of Agriculture Iwate UniversityMoriokaJapan Iwate Agri-Innovation Center Iwate UniversityMoriokaJapan

We supercooled fresh-cut onion at−5℃ for 12 *** supercooling,the electric impedance properties of the samples were evaluated by electrical impedance spectroscopy over the frequency range of 42 Hz−5 *** time-temperature profiles of samples indicated that the freezing point and supercooling point were−2.3℃±0.7℃ and−6.9℃±1.0℃,*** results indicated that 34 of the 36 supercooled samples exhibited a definite circular arc in the Cole-Cole plot,which suggested that the cell membrane remained intact during *** the other two samples which did not exhibit a definite circular arc,the cell membrane had sustained serious damage during ***,there was large difference in drip loss percentage between supercooled samples exhibited a definite circular arc in the Cole-Cole plot and samples not exhibiting a definite circular *** results suggest that fresh-cut onions can be supercooled at−5℃.

关键词： supercooling fresh-cut onion electrical impedance Cole-Cole plot supercooling point