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Infection control in severely burned patients

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World Journal of Critical Care Medicine 2012年第4期1卷 94-101页

作者： Yusuf kenan Coban Burn Unit Department of Plastic Reconstructive and Aesthetic Surgery Turgut Ozal Medical Centre Inonu üniversity Medical Faculty

In the last two decades, much progress has been made in the control of burn wound infection and nasocomial infections(NI) in severely burned patients. The continiually changing epidemiology is partially related to greater understanding of and improved techniques for burn patient management as well as effective hospital infection control measures. With the advent of antimicrobial chemotherapeutic agents, infection of the wound site is now not as common as, for example, urinary and blood stream infections. Universal application of early excision of burned tissues has made a substantial improvement in the control of wound-related infections in burns. Additionally, the development of new technologies in wound care have helped to decrease morbidity and mortality in severe burn victims. Many examples can be given of the successful control of wound infection, such as the application of an appropriate antibiotic solution to invasive wound infection sites with simultaneous vacuum-assisted closure, optimal preservation of viable tissues with waterjet debridement systems, edema and exudate controlling dressings impregnated with Ag(Silvercel, Aquacell-Ag). The burned patient is at high risk for NI. Invasive interventions including intravenous and urinary chateterization, and entubation pose a further risk of NIs. The use of newly designed antimicrobial impregnated chateters or silicone devices may help thecontrol of infection in these immunocomprimised patients. Strict infection control practices(physical isolation in a private room, use of gloves and gowns during patient contact) and appropriate empirical antimicrobial therapy guided by laboratory surveillance culture as well as routine microbial burn wound culture are essential to help reduce the incidance of infections due to antibiotic resistant microorganisms.

关键词： Severe burn injury Infection control Wound care Infection control programs Survelliance

Rhabdomyolysis, compartment syndrome and thermal injury

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World Journal of Critical Care Medicine 2014年第1期3卷 1-7页

作者： Yusuf kenan Coban Burn Unit and Department of Plastic Surgery Inonu University Turgut Ozal Medical Centre 44280 Malatya Turkey

Rhabdomyolysis(RML) after electrical burns and crush injuries is a well-known clinical entity, but its occurrence following thermal injury has not gained so much attention. Capillary leak syndrome and following polycompartmental syndrome are devastating end results of major thermal injuries. In the current review, polycompartment syndrome within the clinical picture of systemic oedema and its relationship to RML is discussed along with its management and prevention.

关键词： Capillary leak syndrome Rhabdomyolysis Thermal injury

Clinical management and survival outcomes of patients withdifferent molecular subtypes of diffuse gliomas in China(2011–2017):a multicenter retrospective study from CGGA

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Cancer Biology & Medicine 2022年第10期19卷 1460-1476页

作者： kenan Zhang Xing Liu Guanzhang Li Xin Chang Shouwei Li Jing Chen Zheng Zhao Jiguang Wang Tao Jiang Ruichao Chai Department of Molecular Pathology Beijing Neurosurgical InstituteCapital Medical UniversityBeijing 100070China Department of Neuropathology Beijing Neurosurgical InstituteCapital Medical UniversityBeijing 100070China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Department of Neurosurgery Beijing Sanbo Brain HospitalCapital Medical UniversityBeijing 100093China Division of Life Science and State Key Laboratory of Molecular Neuroscience Department of Chemical and Biological EngineeringThe Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SAR 999077China Hong Kong Center for Neurodegenerative Diseases Hong Kong Science ParkHong Kong SAR 999077China HKUST Shenzhen-Hong Kong Collaborative Innovation Research Institute FutianShenzhen 518057China

Objective:We aimed to summarize the clinicopathological characteristics and prognostic features of various molecular subtypes of diffuse gliomas(DGs)in the Chinese ***:In total,1,418 patients diagnosed with DG between 2011 and 2017 were classified into 5 molecular subtypes according to the 2016 WHO classification of central nervous system *** IDH mutation status was determined by immunohistochemistry and/or DNA sequencing,and 1p/19q codeletion was detected with fluorescence in situ *** median clinical follow-up time was 1,076 days.T-tests and chi-square tests were used to compare clinicopathological ***‒Meier and Cox regression methods were used to evaluate prognostic ***:Our cohort included 15.5%lower-grade gliomas,IDH-mutant and 1p/19q-codeleted(LGG-IDHm-1p/19q);18.1%lowergrade gliomas,IDH-mutant(LGG-IDHm);13.1%lower-grade gliomas,IDH-wildtype(LGG-IDHwt);36.1%glioblastoma,IDHwildtype(GBM-IDHwt);and 17.2%glioblastoma,IDH-mutant(GBM-IDHm).Approximately 63.3%of the enrolled primary gliomas,and the median overall survival times for LGG-IDHm,LGG-IDHwt,GBM-IDHwt,and GBM-IDHm subtypes were 75.97,34.47,11.57,and 15.17 months,*** 5-year survival rate of LGG-IDHm-1p/19q was 76.54%.We observed a significant association between high resection rate and favorable survival outcomes across all subtypes of primary *** also observed a significant role of chemotherapy in prolonging overall survival for GBM-IDHwt and GBM-IDHm,and in prolonging post-relapse survival for the 2 recurrent GBM ***:By controlling for molecular subtypes,we found that resection rate and chemotherapy were 2 prognostic factors associated with survival outcomes in a Chinese cohort with DG.

关键词： Diffuse glioma IDH 1p/19q molecular pathology temozolomide

Not just a capillary hemangioma

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世界儿科杂志:英文版 2016年第2期12卷 249-249页

作者： Mehmet kenan Kanburoglu Department of Pediatrics Division of NeonatologyDr.Nafi z Korez Sincan Governmental HospitalAnkaraTurkey

A four-day-old female infant with jaundice was admitted to our *** her examination,a capillary hemangioma with a pigmented nevus and a Mongolian spot was noticed(Fig.1).Ultrasound examination revealed spinal dysraphis... 详细信息

关键词： capillary admitted examination

Does Living Abroad Give You a Creative Edge?

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ChinAfrica 2012年第10期4卷 56-57页

作者： Li kenan Jonathan Gandari

Studying Abroad Helps Cultivate Critical Thinking by Li kenan Thinking critically means to discover possibilities outside of those things we take for granted in our lives. Most people live in very confined locations in their whole lives; the particular culture, religion, ideology and classism of our homes construct our stereotyped understandings of the world and block the way of alternative views and innovative thought.

关键词： Li Does Living Abroad Give You a Creative Edge

早期原发性开角型青光眼与帕金森患者SD-OCT检查结果的比较

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国际眼科杂志 2021年第5期21卷 750-756页

作者： kenan Dagdelen Semra Ari Sevingil Eskisehir Yunus Emre State医院眼科土耳其埃斯基谢希尔26190 Eskisehir Yunus Emre State医院神经内科土耳其埃斯基谢希尔26190

目的:使用光学相干断层扫描(SD-OCT)比较早期帕金森病(PD)和原发性开角型青光眼(POAG)患者黄斑和视网膜神经纤维层(RNFL)厚度参数。方法:回顾性分析。选取48例早期POAG患者、34例早期PD患者和37例年龄及性别相匹配的健康志愿者(对照组)... 详细信息

目的:使用光学相干断层扫描(SD-OCT)比较早期帕金森病(PD)和原发性开角型青光眼(POAG)患者黄斑和视网膜神经纤维层(RNFL)厚度参数。方法:回顾性分析。选取48例早期POAG患者、34例早期PD患者和37例年龄及性别相匹配的健康志愿者(对照组),使用SD-OCT分别测量RNFL和9个象限的黄斑厚度(ETDRS分区)。本研究纳入的早期POAG患者视野检测MD0.05)。PD组患者病程、UPDRS评分与黄斑厚度和RNFL厚度均呈负相关。结论:通过SD-OCT对早期POAG和PD患者黄斑和RNFL厚度参数进行检测,发现两者出现相似的变薄现象,而在早期POAG组这种现象更为明显,推测青光眼引起的黄斑神经退行性变比PD更具破坏性,但PD患者黄斑中央凹区变薄更为显著。

关键词：帕金森病青光眼光学相干断层扫描黄斑视网膜神经纤维层

Lower extremity lymphedema and vascularized lymph node transfer recipient sites:a review of the current literature

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Plastic and Aesthetic Research 2023年第1期10卷 701-709页

作者： kenan Tawaklna David Chi Jordan G.Bruce Austin Y.Ha Rachel Anolik Division of Plastic and Reconstructive Surgery Department of SurgeryWashington University in St.LouisSt.LouisMO 63110USA

Vascularized lymph node transfer is a surgical treatment for lower extremity lymphedema aimed at restoring physiological lymphatic *** variation exists in determining the appropriate donor site from which to harvest lymph nodes as well as the optimal recipient site to anastomose the new lymph *** article reviews the underlying principles of free vascularized lymph node transfer and discusses patient-specific,disease-specific and surgery-specific factors in considering recipient sites from the proximal,middle,and distal lower *** clinical outcomes of published studies in lymphatic surgery for lower extremity lymphedema are *** omental flap to the middle lower extremity(mid-thigh,popliteal fossa,or medial calf)is then recommended due to the abundance of lymphatic tissue,proximity to pooled lymph fluid,and avoidance of added bulk or poor cosmesis of the distal lower ***,additional clinical outcomes studies are needed and represent an area of further investigation.

关键词： Lower extremity lymphedema vascularized lymph node transfer physiologic procedure lymph node flap lymphatic flap lymph node donor lymph node recipient lymphangiogenesis

Managing Social Performance A Case of Microfinance

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Chinese Business Review 2011年第10期10卷 906-923页

作者： Muamer Halilbasic kenan Crnkic University of Sarajevo Sarajevo Bosnia and Herzegovina

Global financial crises might and should be recognized as a potential chance to introduce changes in managing our business, both in financial and other important private and/or public sectors. The prevailing opinion is that a lack of corporative social responsibility is one of the major reasons that lead to global crises occurrence. Nowadays, it is crucial to use the experiences of other industries and sectors which from their very beginning managed to balance finance and social goals at the same time. Microfinance sector is exactly one such sector. This paper is organized as follows： First, we give some overview of different approaches to measuring social performance of microfinance institutions. In this part of the paper we also accent the specifics of microfinance institutions-management within the context of double bottom line. In the second part we focus our analysis on practical implementation of ＂double bottom line management in Prizma MCO, one of the world pioneers in social performance management, by using their revolutionary poverty scorecard system. Then, we analyze how these social performance data are used in decision-making and how it affects overall performance of the organization. The paper is finished with some conclusions and lessons learned.

关键词： social performance management microfinance scorecard

A Novel Multi-Points Laser Monitoring of Building Settlement and Its Risk Evaluation

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Wuhan University Journal of Natural Sciences 2019年第5期24卷 442-454页

作者： CHAI Caiping WU Zejian WANG Huifeng GUAN Limin HUANG He MU kenan CUI Wenfen HAO Ting School of Highway & Railway Engineering Shaanxi College of Communication Technology Xi'an 714018 ShaanxiChina School of Electronic & Control Engineering Chang'an University Xi'an 710064 Shaanxi China

Aiming at the defects of routine settlement measurement methods, such as complicated procedures, time-consuming and labor-intensive, high cost and low measurement accuracy, based on the analysis of existing engineering measurement technical requirements and specifications, a multi-point high precision and high efficiency based on laser reference is proposed. The automatic building settlement real-time monitoring system program gives the principle and system model of single-point settlement observation. The model of multi-point scanning settlement monitoring system and the model of multi-point network settlement monitoring system are designed, and their advantages and disadvantages are analyzed. We focus on the networked multi-point settlement monitoring system for network cumulative error analysis, and propose related evaluation and correction methods. The hardware schematic and software block diagram of the laser reference measurement and measurement system of the single point settlement acquisition system are given. Finally, the risk of subsidence state is quantitatively evaluated based on multi-point settlement monitoring data. The measurement error of this method is less than 300 μm, which can realize the monitoring and evaluation of the overall settlement.

关键词： measurement technology laser reference settlement chain linear array Charge-Coupled Device(CCD)