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Medication beliefs predict medication adherence in ambulatory patients with decompensated cirrhosis

World Journal of Gastroenterology 2017年第40期23卷 7321-7331页

作者： kelly l hayward Patricia C Valery Jennifer H Martin Antara Karmakar Preya J Patel leigh U Horsfall Caroline J Tallis Katherine A Stuart Penny l Wright David D Smith Katharine M Irvine Elizabeth E Powell W Neil Cottrell Pharmacy Department Princess Al-exandra Hospital The Centre for Liver Disease Research Translational Research Institute The University of Queensland Cancer and Chronic Disease Research Group QIMR Berghofer Medical Research Institute School of Medicine and Public Health The University of Newcastle The Centre for liver Disease Research Translational Research Institute The University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital The Centre for Liver Disease Research Translational Research Institute The University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital Statistics Unit QIMR Berghofer Medical Research Institute School of Pharmacy The University of Queensland

AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated *** One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky Medication Adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = *** Medication adherence was " High " in 42 % o f participants, "Medium" in 37%, and "low" in 21%. Compared to patients with "High" adherence, those with "Medium" or "low" adherence were more likely to report difficulty affording their medications(P lower perception of treatment helpfulness(P = 0.003) and stronger medication concerns relative to medication necessity beliefs(P = 0.003). People with "low" adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of "low"*** The association between "low" adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explor

关键词： Medication adherence Medication beliefs Illness perceptions Quality of life liver cirrhosis

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用于小型计算机的不归零制记录

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微电子学与计算机 1983年第5期 42-43页

作者： l.hayward 刘建生

大多数小型计算机的磁记录系统采用堪萨斯城盒式磁带记录格式,数据速率限于几百波特。l. hayward为Nascoml和Nascom2计算机提出了一种不归零制记录系统(它所用的电路对于其它机器也是适用的),并且与堪萨斯城标准所用的方法进行了性能比较。

关键词：盒式磁带录音机小型计算机斯密特触发器盒式磁带机磁头磁记录器堪萨斯城波特磁带计算机外围设备

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早期和晚期乳癌治疗现状

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国际肿瘤学杂志 1987年第6期14卷 358-360页

作者： hayward J l ,Rubens R D ,谭景莹

1986年4月,国际抗癌联盟在美国根西召开会议,就近年来乳腺癌防治研究进展及今后研究方向进行了讨论,现综合报道如下。早期乳癌一、预后因素治疗原发性乳癌之首要目标是为每位患者选择适宜的治疗方案,并将腋窝淋巴结状态和肿瘤大小作为... 详细信息

1986年4月,国际抗癌联盟在美国根西召开会议,就近年来乳腺癌防治研究进展及今后研究方向进行了讨论,现综合报道如下。早期乳癌一、预后因素治疗原发性乳癌之首要目标是为每位患者选择适宜的治疗方案,并将腋窝淋巴结状态和肿瘤大小作为预后指征。其他病理学标准为恶性程度级别、淋巴浸

关键词：乳癌局部晚期淋巴结肿瘤大小原发性乳岩淋巴组织乳房切除术内分泌治疗三苯氧胺腋窝

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Tissue culture tools for selenium hyperaccumulator Neptunia amplexicaulis for development in phytoextraction

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Natural Products and Bioprospecting 2022年第1期12卷 409-417页

作者： Billy O’Donohue Jayeni Hiti-Bandaralage Madeleine Gleeson Chris O’Brien Maggie-Anne Harvey Antony van der Ent Katherine Pinto Irish Neena Mitter Alice hayward Centre for Horticultural Science Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandBrisbaneQLDAustralia Centre for Mined land Rehabilitation Sustainable Minerals InstituteThe University of QueenslandBrisbaneQLDAustralia

Neptunia amplexicaulis is an herbaceous legume endemic to the Richmond area in central Queensland,Australia and is one of the strongest known Selenium hyperaccumulators on earth,showing significant potential to be utilised in Se phytoextraction *** a protocol was established for in vitro micropropagation of Se hyperaccumula-tor *** using nodal segments from in vitro-germinated *** multiplication was achieved on Murashige and Skoog(MS)basal media supplemented with various concentrations of 6-Benzylaminopurine(BA)(1.0,2.0,3.0 mg l^(−1))alone or in combination with low levels of Naphthaleneacetic acid(NAA)(0.1,0.2,0.3 mg l^(−1)),with 2.0 mg l^(−1) BA+0.2 mg l^(−1) NAA found to be most *** shoots were rooted in vitro using NAA,with highest root induction rate of 30%observed at 0.2 mg l^(−1) *** 95%of the in vitro rooted shoots survived *** propagated plantlets were dosed with selenate/selenite solution and assessed for Se tissue concentrations using Inductively Coupled Plasma Atomic Emission Spectroscopy(ICP-AES)and found to retain their ability to *** protocol developed for this study has potential to be optimised for generating clonal plants of *** for use in research and phytoextraction industry applications.

关键词： Micropropagation Hyperaccumulation Phytoextraction Selenium Tissue culture Neptunia amplexicaulis

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B-A电离真空计中反X射线电流

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真空 1965年第6期 27-32页

作者： W.H.hayward ,R.l.JEPSEN ,P.A.REDHEAD 加拿大喔太华国家研究会

产生在Ｂ－Ａ规管栅极的软Ｘ射线，引起规管壁发射光电子。如果离子收集极工作电位接近管壁，一部分光电子将有能力到达收集极。一小部份穿过栅极实际上到达收集，因此增加一个与普通Ｘ射线电流方向相反的残余电流分量，引起规管Ｘ射线... 详细信息

产生在Ｂ－Ａ规管栅极的软Ｘ射线，引起规管壁发射光电子。如果离子收集极工作电位接近管壁，一部分光电子将有能力到达收集极。一小部份穿过栅极实际上到达收集，因此增加一个与普通Ｘ射线电流方向相反的残余电流分量，引起规管Ｘ射线限制的减小。只要规管几何形伏和工作电压配合得当，将净Ｘ射线限制可以降到零甚至可能是负的。

关键词：规管限制几何形 B-A 电流

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克鲁郡的导弹

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汽车与运动 2014年第9期 22-23页

作者： Matthew hayward 马爽

宾利欧陆GT3-R的双涡轮增压发动机可以爆发出427kW的最大功率,得益于轻量化管理,车身减重100kg。3.8s的0~100km/h加速成绩使其成为了宾利最快的量产车在今年的古德伍德赛车节上,宾利欧陆GT3-R正式亮相。该车0~100km/h加速是目前宾利量... 详细信息

宾利欧陆GT3-R的双涡轮增压发动机可以爆发出427kW的最大功率,得益于轻量化管理,车身减重100kg。3.8s的0~100km/h加速成绩使其成为了宾利最快的量产车在今年的古德伍德赛车节上,宾利欧陆GT3-R正式亮相。该车0~100km/h加速是目前宾利量产车中最快的,同时也是最具活力的。它的设计灵感来自在宝珀耐力赛第二站银石赛道比赛中取得冠军的欧陆GT3赛车。在发动机盖下面的是一台来自欧陆GT的4.0l双涡轮增压V8发动机,由于增加了涡轮增压器的进气压力。

关键词：宾利量产车古德伍德涡轮增压发动机涡轮增压器量化管理克鲁车节最大功率双涡轮增压

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分子的建筑术

分子的建筑术

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作者：波林(l. Pauling) R.·海沃德(R. hayward)

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Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATlAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios l. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.l. Alberghi J. Albert P. Albicocco G.l. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo l. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines l. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli l.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal l. Barak M. Barakat E.l. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATlAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATlAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATlAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATlAS JET QUARK GlUON TAGGING

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Tropical forest canopies and their relationships with climate and disturbance： results from a global dataset of consistent field-based measurements

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Forest Ecosystems 2018年第1期5卷 77-90页

作者： marion pfeifer alemu gonsamo william woodgate luis cayuela andrew r.marshall alicia ledo timothy c.e.paine rob marchant andrew burt kim calders colin courtney-mustaphi aida cuni-sanchez nicolas j.deere dereje denu jose gonzalez de tanago robin hayward alvaro lau manuel j.macía pieter i.olivier petri pellikka hamidu seki deo shirima rebecca trevithick beatrice wedeux charlotte wheeler pantaleo k.t.munishi thomas martin abdul mustari philip j.platts school of natural and environmental sciences newcastle universityUpon TyneNewcastle NE1 7RUUK department of geography and planning university of torontoONCanada land and water commonwealth scientific and industrial research organisationYarralumlaACTAustralia school of mathematical and geospatial sciences rmit universityGPO Box 2476VMelbourneVIC 3001Australia department of biology geologyphysics and inorganic chemistryuniversidad rey juan carlosE-28933 MostolesMadridSpain tropical forest and peopleresearch centre university of the sunshine coastsippy DownsAustralia environment department university of yorkYorkUK flamingo land ltd. MaltonUK the institute of biological and environmental sciences environmental modelling groupuniversity of aberdeenAberdeenUK biological and environmental sciences university of stirlingStirling FK9 4L AUK york institute for tropical ecosystems environment departmentuniversity of yorkYork YO10 5NGUK department of geography university college londonGower StreetLondon WC1E 6BTUK earth observation climate and optical groupnational physical laboratoryHampton RoadTeddingtonMiddlesex TW11 0LWUK department of archaeology and ancient history uppsala universitetP.O.Box 256-751 05 UppsalaSESweden center for macroecology evolution and climateuniversity of copenhagenUniversitetsparken 152100 CopenhagenDKDenmark durrell institute of conservation and ecology(dice) school of anthropology and conservationuniversity of kentCanterbury CT2 7NRUK department of biology college of natural sciencesjimma universityJimmaEthiopia wageningen university&research laboratory of geo-information science and remote sensingDroevendaalsesteeg 36708 PB Wageningenthe Netherlands center for international forestry research(cifor) Situ GedeSindang BarangBogor 16680Indonesia departamento de biología área de botánicauniversidad autónoma de madridcalle Darwin 2-28049 MadridESSpain conservation ecology research unit university of pretoriaHatfieldPretoriaSouth Af

Background： Canopy structure, defined by leaf area index （lAI）, fractional vegetation cover （FCover） and fraction of absorbed photosynthetically active radiation （fAPAR）, regulates a wide range of forest functions and ecosystem services. Spatially consistent field-measurements of canopy structure are however lacking, particularly for the tropics. Methods： Here, we introduce the Global lAI database： a global dataset of field-based canopy structure measurements spanning tropical forests in four continents （Africa, Asia, Australia and the Americas）. We use these measurements to test for climate dependencies within and across continents, and to test for the potential of anthropogenic disturbance and forest protection to modulate those dependences. Results： Using data collected from 887 tropical forest plots, we show that maximum water deficit, defined across the most arid months of the year, is an important predictor of canopy structure, with all three canopy attributes declining significantly with increasing water deficit. Canopy attributes also increase with minimum temperature, and with the protection of forests according to both active （within protected areas） and passive measures （through topography）. Once protection and continent effects are accounted for, other anthropogenic measures （e.g. human population） do not improve the model. Conclusions： We conclude that canopy structure in the tropics is primarily a consequence of forest adaptation to the maximum water deficits historically experienced within a given region. Climate change, and in particular changes in drought regimes may thus affect forest structure and function, but forest protection may offer some resilience against this effect.

关键词： leaf area index Fractional vegetation cover Fraction of absorbed photosynthetically active radiation,Human population pressure Protected areas Drought Climate change

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Spontaneous immortalization of human dermal microvascular endothelial cells

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World Journal of Stem Cells 2010年第5期2卷 114-120页

作者： laura DeBusk Suzanne Fernandez Douglas W Strand Simon W hayward P Charles lin Department of Radiation Oncology Vanderbilt University Medical Center Department of Urologic Surgery Vanderbilt University Medical Center Center for Cancer Research National Cancer Institute

AIM:To establish and characterize a spontaneously immortalized human dermal microvascular endothelial cell line,***:We developed a spontaneous immortalization *** approach is based on the application of optimized culture media and culture conditions without addition of any exogenous oncogenes or *** this approach,we have successfully established a microvascular endothelial cell line,iHDME1,from primary human dermal microvascular endothelial ***1 cells have been maintained in culture dishes for more than 50 passages over a period of 6 *** a GFP expressing retrovirus,we generated a GFP-stable cell line(iHDME1-GFP).RESUlTS:iHDME1 retain endothelial morphology and uniformly express endothelial markers such as VEGF receptor 2 and VE-cadherin but not α-smooth muscle actin(α-SM-actin) and cytokeratin 18,markers for smooth muscle cells and epithelial cells *** cells retain endothelial properties,migrate in response to VEGF stimulation and form 3-D vascular structures in Matrigel,similar to the parental *** is no signif icant difference in cell cycle prof ile between the parental cells and iHDME1 *** analysis indicates enhanced stemness in iHDME1 cells compared to parental ***1 cells display elevated expression of CD133 and ***:iHDME1 cells will be a valuable source for studying angiogenesis.

关键词： Spontaneous immortalization Angiogenesis Endothelial cell

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