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Genotoxicity of Synthetic Food Colorants

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Journal of Food Science and Engineering 2011年第2期1卷 128-134页

作者： V. R. Swaroop d. dinesh Roy T. Vii ayakumar School of Environmental Sciences Mahatma Gandhi University Kottayam Kerala 686560 India

A study was conducted to evaluate the genotoxicity, if any, of the permitted synthetic food colorants used in India. Eight synthetic food colorants namely Erythrosine （E 127）, Tartrazine （E 102）, Ponceau 4R （E 124）, Sunset Yellow FCF （E 110）, Brilliant Blue FCF （E133）, Fast Green FCF （E143）, Carmoisine （E122） and Indigo Carmine （E132） and their combination are used in sweets namely Ladu, Jilebi and Halwa in Calicut and suburban areas of Kerala, in India. The genotoxicity of the colorants alone and in combinations at different concentrations were evaluated by Cytokinesis Block Micronucleus （CBMN） Assay. It was observed that all the above colorants and their combinations could cause genotoxicity to human lymphocytes even at the permissible concentration of 100 ppm as per PFA （Prevention of Food Adulteration） Act of India. The toxicity varied from dye to dye and was proportional to their concentration. Combination of colors showed more toxicity than the individual components. Toxicity could be reduced drastically by reducing the concentration of the dyes at least 50% below the permissible limit. Permitted synthetic food colorants even at the permissible limit should be used with caution. This study demonstrated the need for redefining the permissible limit of the food colorants based on Admissible daily Intake （AdI） as being practiced in developed countries.

关键词： Synthetic food colorants genotoxicity CBMN (Cytokinesis Block Micronucleus) Assay somatic dNA damage foodadulteration AdI (Admissible daily Intake).

Investigation of lnter and Intra-fractional Uncertainties in Lung IMRT delivery

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Chinese Journal of Biomedical Engineering(English Edition) 2017年第1期26卷 1-4页

作者： Maria das KJ Arpita Agarwal Yoganathan SA Gowtharu Raj d Shaleen Kumar department of Radiotherapy Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknowIndia

Changes in the tumour position due to inter and intra-fractional motion introduce uncertainty in IMRT delivery. In this work, we experimentally evaluated the effect of inter and intra-fractional motion uncertainties in the IMRT delivery. A lung patient was planned with rive field dynamic IMRT for a total dose of60 Gy in 30 fractions using 6 MV photon beam at a dose rate of 400 MU/min. The plan was delivered on varian CL2100 Cd linear accelerator with millennium 120 MLC for a single fraction and measured using IMRT Matri XX placed on Quasar motion platform, aligned with respect to isocentre for planar as well as point dose measurements. This measurement was summated for 30 fractions and taken as a reference. 30 measurements were performed for each inter-fractional, intra-fractional and combined effect. The setup errors(Mean+Sd) used to simulate the inter-fractional displacements were RL:-0.10+0.27 mm, SI: 0.17+0.45 mm, AP:-0.04+0.38 mm and Rot: 0.02+0.86 degree. The intra-fractional motion was simulated using the motion platform parallel to the MLC leaf motion, for an amplitude of 1 cm and a period of 4 s. The planner fluence of inter, intra-fractional motion and combination of both was analyzed against the reference using gamma criteria of 3%/3 mm. Similarly, the point dose measurements were also compared. The maximum deviation in point dose during a single fraction was-3.8%, 3.1% and-5.9% for inter-fractional, intra-fractional and combined respectively. The same resulted in deviation of-0.4%,-0.3% and 0.1% respectively when summated for 30 *** percentage of pixels failing the gamma criteria during a single fraction was28.0%, 16.4% and 28.5% for inter-fractional, intra-fractional and combined respectively. The same revealed 11.4%, 12.4% and 19.2% respectively when summated. Though the point dose deviations were nullified over 30 fractions, the planner fluence variation was observed to be considerable.

关键词： MRT inter-fraction intra-fraction uncertainties

颅内肿瘤:脑池角作为中脑压迫的测量指标以评估肿瘤栓塞术后临床恶化风险

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国际医学放射学杂志 2009年第4期32卷 397-397页

作者： R. Gilad G.M. Fatterpekar C.d. gandhi H.R. Winn d.M. Johnson A.B. Patel 杨静（译）张雪宁（校） department of Neurosurgery Mount Sinai School of Medicine 1 Gustave Levy Pl New YorkNY 10029. 不详

目的确定预示颅内大的肿瘤行栓塞术后临床恶化的客观影像学特征。方法本回顾性研究符合HIPAA法案,并得到机构伦理委员会的批准,免除知情同意书。在12例颅内大的肿瘤并接受过栓塞术治疗的病人中,分析有可能预示栓塞术后神经系统病情急性... 详细信息

目的确定预示颅内大的肿瘤行栓塞术后临床恶化的客观影像学特征。方法本回顾性研究符合HIPAA法案,并得到机构伦理委员会的批准,免除知情同意书。在12例颅内大的肿瘤并接受过栓塞术治疗的病人中,分析有可能预示栓塞术后神经系统病情急性恶化的影像学特征。运用脑池角（沿大脑脚前缘划线和正中矢状面所形成的夹角）来计算巾脑压迫的程度。用血管造影来评估肿瘤栓塞术前和术后肿瘤染色的程度。对于栓塞术前、后病人的神经功能状态进行评估。

关键词：颅内肿瘤栓塞术后急性恶化脑压迫评估临床脑池机构伦理委员会

头颈部鳞癌:CT灌注有助于无创性预测瘤内微血管密度

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国际医学放射学杂志 2009年第4期32卷 381-381页

作者： L. Ash T.N. Teknos d. gandhi S. Patel S.K. Mukherji. 高光峰（译）夏爽（校） department of Radiology Division of Neuraradiology University of Michigan Health Systems 1500 E Medical Center Drive Ann Arbor M148109-0030 USA. 不详

目的在头颈部鳞癌评估中．确定CT灌注成像参数与瘤内微血管密度的相关性。方法此项符合HIPPA的前瞻性研究得到了当地伦理委员会批准，所有参加本研究的病人均签署知情同意书。13例进展期头颈部鳞癌病人（Ⅲ和Ⅳ期）进行了颈部CT增强、C... 详细信息

目的在头颈部鳞癌评估中．确定CT灌注成像参数与瘤内微血管密度的相关性。方法此项符合HIPPA的前瞻性研究得到了当地伦理委员会批准，所有参加本研究的病人均签署知情同意书。13例进展期头颈部鳞癌病人（Ⅲ和Ⅳ期）进行了颈部CT增强、CT灌注成像和原发肿瘤的内镜活检。病人的平均年龄为57．4岁（范围为41～78岁）。经小鼠抗人类Cd31抗体免疫染色后，检测瘤内微血管密度。记录每一标本在10个高倍视野（×400）下的平均染色微血管数目。

关键词：瘤内微血管密度 CT灌注成像头颈部鳞癌无创性预测免疫染色伦理委员会知情同意书成像参数

分析性评价:英迪拉·甘地国立开放大学对不利人群的影响

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中国远程教育 1999年第11期 17-19,62页

作者： d.B.纳吉印度英迪拉.甘地国立开放大学

India gandhi National Open University (IGNOU) has completed 13 years of its existence with over 0.5million students on roll. It is interesting to note that the total number of students belonging to ScheduledCaste (SC), Scheduled Tribe (ST) and women are settling at a level of around 6%,3% arid 25co respectively,though the main objective of the university is to provide education, among other things, to "large segment ofsociety" with special emphasis on the disadvantaged groups. In the present paper, the data has been collectedfrom various sources to analyse casual factor for low enrolment of SC,ST and women groups. This gives acontrary view and not in proportion to their demographic position in the society. Besides this, an attempt hasbeen made to offer some measures to improve the enrolment of these groups. In brief, the present paper intends to critically analyse the following aspects of IGNOU impact on the disadvantaged groups: *** ofenrolment of SC, ST and women groups in IGNOU *** of low enrolment. *** suggested for further improvement of education among the disadvantaged groups.

关键词：开放大学分析性对不利消除对妇女的歧视识字率印度妇女教育机构数量处于不利地位社会底层远程教育

Study of a crop-pest-natural enemy model with Z-type control——An approach to pest management

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International Journal of Biomathematics 2023年第4期16卷 175-207页

作者： dibyendu Sekhar Mandal Sudip Samanta Rana d.Parshad Abdennasser Chekroun Mohamed Helal Joydev Chattopadhyay department of Mathematics AmityUniversity Maharashtra Mumbai Maharashtra 410206India Agricultural and Ecological Research Unit Indian Statistical Institute 203B.T.Road Kolkata 700108India department of Mathematics Bankura University WestBengal722155India department of Mathematics Iowa State University AmesIA 50011USA Laboratoire d'Analyse Nonlineaire et Mathematiques Appliquees University of Tlemcen Tlemcen 13000Algeria Biomathematics Laboratory Universite Sidi Bel-Abbes P.B.8922000Algeria

In this study,the Z-type control method is applied to an intraguild crop-pest-natural enemy model,assuming that the natural enemy can predate on both crop and pest *** this purpose,the indirect Z-type controller is considered in the natural enemy *** providing the design function for the crop-pest-natural enemy model with Z-control,we find the analytical expression of the update *** findings indicate that the uncontrolled system can produce chaos through perioddoubling bifurcation due to crop over-consumption by the pest *** draw a Poincare map to confirm the occurrence of chaos and compute the maximum Lyapunov *** the observations further indicate that the pest population can be controlled by using an indirect Z-control mechanism in the natural enemy population,we postulate that,if natural enemy abundance can be governed by the update parameter,any desired pest population abundance can be achieved through the proposed Z-type controller,thus controlling the *** verify these assertions,extensive numerical simulations are performed to explore the potential for practical application of the proposed Z-type controller.

关键词： Crop-pest-natural enemy model Z-type control numerical simulations pest control

development of Multilevel Meteorological data Acquisition System for Radiation Emergency decision Support

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Journal of Earth Science and Engineering 2013年第8期3卷 545-553页

作者： d.N. Krishnakumar A. Bagavath Singh Anjukumari R. Baskaran M.T. Jose B. Venkatraman Radiological Safety division Indira Gandhi Centre for Atomic Research Kalpakkam 603102 Tamilnadu India

This paper describes a development of multilevel meteorological data acquisition system implemented at Kalpakkam coastal site for atmospheric dispersion and model validation studies. Meteorological data are one of the most important inputs into any air dispersion model. As a part of atmospheric dispersion modeling studies and developing a methodology to forecast the site-specific dispersion characteristics, the real time monitoring of meteorological parameters assumes significance. This is achieved by erecting met towers instrumented at multilevel and single level at different locations with sensors for measuring various meteorological parameters. Real-world data logging applications involve not only just acquiring and recording signals, but also combination of offline analysis, display, report generation and data sharing. This paper covers development of low cost compact MMdAS （modular meteorological data acquisition system）, its performance evaluation, field deployment test and data comparison analysis with fast response and high accuracy internationally acclaimed sonic anemometer. The system is based on embedded modules from Advantech and is designed to acquire analogue and digital signals from a multilevel instrumented met tower. The collected data are transferred from remote base station to central server for storage and further processing using wireless interface. MMdAS has many advantages like cost effectiveness, less complex signal conditioning electronics and easy maintenance. This system has good application during radiation emergency as well as site specific meteorological data collection and model validation studies.

关键词： Radiation emergency meteorological data acquisition MMdAS dispersion modeling sonic anemometer.

Phenotypic Characterization and Prevalence of Carbapenemase-Producing Acinetobacter baumanii Isolates in Four Health Facilities in Cameroon

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Certification Process of Imported Pacific White Shrimp Litopenaeus vannamei （Boone, 1931） at Aquatic Quarantine Facility, India

Open Journal of Medical Microbiology（医学微生物学） 2023年第3期

作者： Cécile Ingrid djuikoue Benhamed Nadjia Paule dana djouela djoulako Celianthe Guegang Cedric Seugnou Nana Hélène Valérie Same Njanjo Yemina Grace Kombeu Christiane Kiyang Possi Rodrigue Kamga Wouambo gandhi Ndieffouo Fosso Merimé Joel Tchinda Talokou Bianca Tchounga Chimi Olivier Pomte Agbor Michael Benjamin d.Thumamo Pokam Nicolas Antoine-Moussiaux

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Journal of Agricultural Science and Technology(B) 2011年第6期1卷 783-789页

作者： M. C. Remany dalyCyriac d. Kannanl, A. K. Panda Jaideep Kumar Y. C. Thampi Samraj Aquatic Quarantine Facility for L. vannamei Rajiv Gandhi Centre for Aquaculture TNFDC Hatchery Complex Neelankarai Chennai 600041 Tamil Nadu India Technology Transfer Training ＆ Administrative Complex Rajiv Gandhi Centre for Aquaculture Nagapattinam Sirkali 609109 Tamil Nadu India

The Aquatic Quarantine Facility （AQF） for Litopenaeus vannamei established under the department of Animal Husbandry, dairying and Fisheries, Ministry of Agriculture is located on the eastern coastal region of Chennai in Tamil Nadu, India. The facility is an approved quarantine premise for the SPF vannamei broodstock imported across India and is probably the only one of its kind to be established in Southeast Asia. The centre is managed and operated by Rajiv gandhi Centre for Aquaculture （RGCA）, a technical extension of the Marine Products Export development Authority （MPEdA）, Ministry of Commerce ＆ Industry, Government of India. The quarantine facility functions on the basis of strict biosecurity protocol and as per the guidelines stipulated in Standard Operating Procedures （SOP） framed by a team of experts. The facility ensures specific pathogen free status of the SPF L. vannamei broodstock imported to India, thus playing key role in restricting the entry of diseases to the Country. This article presents the SPF certification process of the imported L. vannamei carried out at the facility.

关键词： Aquatic quarantine facility specific pathogen free standard operating procedures L. vannamei broodstock and biosecurity.