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英国地铁干线地上地铁列车

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国外铁道车辆 2017年第4期54卷 14-16页

作者： keith Barrow 张希

介绍了伦敦地铁d78车辆的改造方案及改造后的用途。

关键词：地铁车辆英国

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A JNK signaling pathway is involved in LPS-induced indoleamine 2,3-dioxygenase expression in an interferon-γ-independent manner in primary murine microglia

A JNK signaling pathway is involved in LPS-induced indoleami...

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中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Marcus A.Lawson Robert dantzer keith W.Kelley Integrative Immunology and Behavior Program department of Animal Sciences College of ACESUniversity of Illinois at Urbana-ChampaignUSA

＜正＞Chronic inflammation is often associated with clinical *** studies have focused on potential mechanisms that might link inflammation-induced depression to tryptophan metabolism,particularly in the brain,where a reduction in the bioavailability of tryptophan could affect serotoninergic neurotransmission and play a synergistic role in the induction of depressive symptoms.A pivotal protein that has recently been shown to be required for development of inflammation-induced depressive-like behavior in mice is indoleamine 2,3-dioxygenase（IdO）,the first rate-limiting tryptophan -degrading enzyme in the kynurenine *** of this enzyme by inflammatory signals leads to an increase in the kynurenine/tryptophan ratio in plasma and the generation of neuroactive mediators,including 3- hydroxykynurenine（3-HK） and quinolinic acid（QUIN）.High levels of 3-HK and QUIN induce neuronal damage via oxidative stress and over stimulation of N-memyl-d-aspartate（NMdA） *** we investigated the mechanism of IdO expression following acute activation of the innate immune system by lipopolysaccharide（LPS） in primary cultures of microglia derived from neonatal C57BL/6 ***（10 ng/ml） induced IdO transcripts that peaked at 8 h and enzymatic activity at 24 h,resulting in an increase in extracellular kynurenine,the catabolic product of IdO-induced tryptophan *** IdO induction by LPS was accompanied by synthesis and secretion of the proinflammatory cytokines TNFαand IL-6,but without detectable IFNγ*** explore the mechanism of LPS-induced IdO expression, microglia were pretreated with the c-Jun N-terminal kinase（JNK） inhibitor SP600125 for 30 min before LPS *** found that SP600125 blocked JNK phosphorylation and significantly decreased IdO expression induced by LPS,which was accompanied by a reduction of LPS-induced expression of TNFαand ***,these data extend to microglia the property that LPS induces IdO expression v

关键词： nitric oxide indoleamine 2,3-dioxygenase lipopoly saccharide kynurenine interferon-7 primary microglia

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3-d ANALYTIC SIGNAL IN THE INTERPRETATION OF TOTAL MAGNETIC FIELd dATA AT LOW MAGNETIC LATITUdES

3-D ANALYTIC SIGNAL IN THE INTERPRETATION OF TOTAL MAGNETIC ...

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理论与应用地球物理研讨会

作者： Ian N. MacLeod keith Jones Ting Fan nai Geosoft Inc. 85 Richmond St.W.8th Floor Toronto Ontario M5H-2C9 Canada Ashton Mining Limited 24 Outram Street West Perth Western Australia 6005

＜正＞ The interpretation of magnetic field data at low magnetic latitudes is difficult because the vector nature of the magnetic field increases the complexity of anomalies from magnetic rocks. The most obvious approach to this problem is to reduce the data to the magnetic pole, where the presumably vertical magnetization vector will simplify observed anomalies. However, RTP requires special treatment of North-South features in data observed in low magnetic latitudes due to high amplitude corrections of these features. Furthermore, RTP requires the assumption of induced magnetization with the result that anomalies from remanently and anisotropically magnetized bodies can be severely *** amplitude of the 3-d analytic signal of the total magnetic field produces maxima over magnetic contacts regardless of the direction of magnetization. The absence of magnetization direction in the shape of analytic signal anomalies is a particularly attractive characteristic for the interpretation of magnetic field data near the magnetic equator. Although the amplitude of the analytic signal is dependent on magnetization strength and the direction of geologic strike with respect to the magnetization vector, this dependency is easier to deal with in the interpretation of analytic signal amplitude than in the original total field data or pole reduced magnetic field. It is also straight forward to determine the depth to sources from the distance between inflection points of analytic signal anomalies.

关键词： analytic signal magnetic interpretation reduction to the pole magnetic depth

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在3d叠前深度偏移中考虑各向异性的影响——北海南部的一个研究实例

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石油物探译丛 2001年第5期 38-49页

作者： keith Hawkins 乔大军中原油田国际公司河南濮阳457001

本文介绍了对北海荷兰海域L10区块的地震资料进行3d各向异性叠前深度偏移(APS-dM)处理的实例研究结果.L10区块的产气层是该区典型的储集层,这是因为他们存在于赤底统地层的地垒和倾斜断块中.由于存在一个受到盐丘构造严重影响的复杂上... 详细信息

本文介绍了对北海荷兰海域L10区块的地震资料进行3d各向异性叠前深度偏移(APS-dM)处理的实例研究结果.L10区块的产气层是该区典型的储集层,这是因为他们存在于赤底统地层的地垒和倾斜断块中.由于存在一个受到盐丘构造严重影响的复杂上覆岩层,因此,对这些断块进行成像变得非常困难,尤其是上覆岩层中还包括速度快和垂向速度梯度大的白垩岩.

关键词：各向异性视各向异性 3d叠前深度偏移深度成像地震勘探

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Bright spots for inland fish and fisheries to guide future hydropower development

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Water Biology and Security 2022年第1期1卷 81-99页

作者： William M.Twardek Ian G.Cowx Nicolas W.R.Lapointe Craig Paukert T.douglas Beard Elena M.Bennett david Browne Andrew K.Carlson keith d.Clarke Zeb Hogan Kai Lorenzen Abigail J.Lynch Peter B.McIntyre Paulo Pompeu Mark Rogers Alexis Sakas William W.Taylor Taylor d.Ward Zeenatul Basher Steven J.Cooke Fish Ecology and Conservation Physiology Laboratory Department of Biology and Institute for Environmental StudiesCarleton University1125 Colonel By DrOttawaON K1S 5B6Canada Fisheries Institute at the University of Hull Cottingham RdHullHU67RXUnited Kingdom Canadian Wildlife Federation 350 Michael Cowpland DrKanataONK2M 2W1Canada U.S.Geological Survey Missouri Cooperative Fish and Wildlife Research UnitUniversity of MissouriColumbiaMO65211United States U.S.Geological Survey National Climate Adaptation Science Center12201 Sunrise Valley DriveMS-516RestonVA20192United States McGill School of Environment McGill University845 Sherbrooke St WMontrealQuebec H3A 0G4Canada Princeton Environmental Institute and department of Ecology and Evolutionary Biology Princeton UniversityM30 Guyot HallPrincetonNJ08544United States Ecological Sciences Section Science Branch Fisheries and Oceans CanadaCanadaPO Box/CP 5667St.John'sNewfoundland and LabradorA1C 5X1Canada University of Nevada Reno.4505 S Maryland PkwyLas VegasNV89154United States Fisheries and Aquatic Sciences School of Forest Resources and ConservationUniversity of Florida7922 NW 71st StreetGainesvilleFL32653United States department of Natural Resources Cornell UniversityIthacaNY14853United States departamento de Biologia Universidade Federal de LavrasAquenta SolLavrasState of Minas Gerais37200-900Brazil U.S.Geological Survey Tennessee Cooperative Fishery Research UnitTennessee tech UniversityCookevilleTN38505United States The Nature Conservancy 6375 Riverside DriveSuite 100DublinOH43017United States Michigan State University Department of Fisheries and WildlifeEast LansingMI48823United States

Hydropower production is one of the greatest threats to fluvial ecosystems and freshwater *** that we have entered the Anthropocene,there is an opportunity to reflect on what might constitute a‘sustainable’Anthropocene in the context of hydropower and riverine fish *** elements of existing practices that promote favorable social-ecological outcomes(i.e.,‘bright spots’)is timely given that there are plans to expand hydropower capacity in previously undammed rivers,intensify dam development in some of the world's largest river systems,and re-license existing *** approach this from a pragmatic perspective:for the foreseeable future,hydropower will likely remain an important source of renewable *** offer support for moving toward a more‘sustainable’Anthropocene,we provide syntheses of best practices during the siting,design,construction,operation,and compensation phases of hydropower development to minimize impacts on inland *** each phase,we offer positive examples(or what might be considered‘bright spots’)pertaining to some of the approaches described within our syntheses,acknowledging that these projects may not be viewed as without ecological and(or)societal detriment by all *** findings underscore the importance of protecting critical habitat and free-flowing river reaches through careful site selection and basinscale planning,infrastructure designs that minimize reservoir effects and facilitate safe passage of fish,construction of hydropower plants using best practices that minimize long-term damage,operating guidelines that mimic natural flow conditions,and compensation that is lasting,effective,inclusive,and locally *** from these‘bright spots’may require engagement of diverse stakeholders,professionals,and governments at scales that extend well beyond a given site,river,or even ***,environmental planning that integrates hydropower development into broader discussions

关键词： Migration dams Salmon Hydroelectric Flow Socioecological Fish passage Barriers Ecosystems

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苦海求生

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作者： (美)萧邦齐(R. keith Schoppa)

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The Effects of Heat Shock on the d-Values of <i>Listeria monocytogenes</i>on Selected Seafood Matrices

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Advances in Microbiology 2015年第8期5卷 580-585页

作者： Michael V. Wood Aswathy Sreedharan Rachael Silverberg Alina N. Balaguero keith R. Schneider department of Food Science and Human Nutrition University of Florida Gainesville FL USA

With more ready-to-eat foods and increased shelf-lives, prevention of Listeria monocytogenes contamination has become a necessity for the food industry. This study examined the effects of sublethal heat treatment on the decimal reduction time (d-values) of three L. monocytogenes serotypes (1/2a, 1/2b, 4c), and non-pathogenic L. innocua. The d70 (d-value at 70℃) values of heat-shocked (HS) and non-heat-shocked (NHS) Listeria grown in tryptic soy broth (TSB) were determined. The d70 values of HS L. monocytogenes serotype 1/2a and L. innocua were significantly higher compared to NHS cultures, although by 48 h, the values returned to NHS levels. When HS and NHS 1/2a and 1/2b were inoculated on crab meat and cooked shrimp, the d70 values of HS cultures were at least 2-fold higher, compared to when they were grown in TSB. This increase in heat resistance for the HS cultures may be attributed to the protective effect of the seafood matrix itself.

关键词： Listeria monocytogenes Ready-to-Eat Seafood Heat Shock d-Value

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空袭伊拉克美国航母飞行员自述 1版

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1998年

作者：（美）谢尔曼·鲍德温（Sherman baldwin）王振西等译

0409020304

ISBN: (数字)7800402975

ISBN: (纸本)7800402975

0409020304

关键词：政治、法律外交、国际关系国际关系

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尼泊尔农村地区孕期妇女补充维生素A对青春期前儿童肺功能的影响:一项随机、双盲、安慰剂对照的队列研究

尼泊尔农村地区孕期妇女补充维生素A对青春期前儿童肺功能的影响:...

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作者： William Checkly keith P West Robert Wise Matthew R baldwin Steven C LeClerq Lee Wu Parul Christian Joanne Tielsch Subaran Khatry Alfred Sommer 张喆庆 Instructor Division of Pulmonary and Critical CareSchool of MedicineThe Johns Hopkins University.1830 Monument StreetFifth FloorBaltimoreMD21205

背景和目的:维生素A(VA)对婴幼儿早期的肺功能发育具有非常重要的作用。母亲孕期VA缺乏将对下一代肺功能健康产生不良的影响。我们为长期处于VA摄入不足的妊娠妇女补充VA或β胡萝卜素(βC),拟验证母亲孕期补充VA与其孩子9～13岁时肺功...

背景和目的:维生素A(VA)对婴幼儿早期的肺功能发育具有非常重要的作用。母亲孕期VA缺乏将对下一代肺功能健康产生不良的影响。我们为长期处于VA摄入不足的妊娠妇女补充VA或β胡萝卜素(βC),拟验证母亲孕期补充VA与其孩子9～13岁时肺功能之间的相关性。方法:随访尼泊尔乡村部分年龄在9～13岁的青春前期

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困扰致密天然气勘探开发的岩石物理问题

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青海石油 2014年第4期32卷 35-42页

作者：彭晓群 Mike Miller keith Shanley 青海油田对外合作部美国西马莱克斯能源公司

很久以前美国能源界就认识到大量的天然气资源赋存于低渗透率岩层中。在上个世纪70年代晚期,美国联邦能源管理委员会(FERC)指定了针对渗透率低于0.1m d储层开发的税收优惠政策,优惠政策的出台加速了致密气资源的广泛开发。非常规气资源... 详细信息

很久以前美国能源界就认识到大量的天然气资源赋存于低渗透率岩层中。在上个世纪70年代晚期,美国联邦能源管理委员会(FERC)指定了针对渗透率低于0.1m d储层开发的税收优惠政策,优惠政策的出台加速了致密气资源的广泛开发。非常规气资源在美国天然气总产量中不断增长,引起了世界各大能源公司的关注。非常规气资源包括三种主要类型:致密砂岩气(低渗透率)、页岩气、煤层甲烷。致密天然气产量目前占美国除阿拉斯加和夏威夷以外48个州非常规天然气产量的35%。尽管经过30多年的工业开发并认识到非常规天然气是美国国内油气产量的不可或缺的组成部分,但致密气开发还是面临巨大的挑战。本文着重就一直困扰致密天然气勘探开发的几个基本岩石物理问题进行讨论。

关键词：致密天然气储层物性

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